{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,4,23]],"date-time":"2024-04-23T16:13:37Z","timestamp":1713888817914},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2013,2,27]],"date-time":"2013-02-27T00:00:00Z","timestamp":1361923200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dig Dis Sci"],"published-print":{"date-parts":[[2013,7]]},"DOI":"10.1007\/s10620-013-2587-z","type":"journal-article","created":{"date-parts":[[2013,2,26]],"date-time":"2013-02-26T06:47:53Z","timestamp":1361861273000},"page":"1891-1898","source":"Crossref","is-referenced-by-count":3,"title":["The Mechanism of the Down-Regulation of Hepatic Transporters in Rats with Indomethacin-Induced Intestinal Injury"],"prefix":"10.1007","volume":"58","author":[{"given":"Nobuhiro","family":"Fujiyama","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshihisa","family":"Shitara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshiharu","family":"Horie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2013,2,27]]},"reference":[{"key":"2587_CR1","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1053\/gast.1997.v112.pm9041264","volume":"112","author":"JL Wallace","year":"1997","unstructured":"Wallace JL. Nonsteroidal anti-inflammatory drugs and gastroenteropathy: the second hundred years. Gastroenterology. 1997;112:1000\u20131016.","journal-title":"Gastroenterology"},{"key":"2587_CR2","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/BF01213310","volume":"32","author":"NM Davies","year":"1997","unstructured":"Davies NM, Wallace JL. Nonsteroidal anti-inflammatory drug-induced gastrointestinal toxicity: new insights into an old problem. J Gastroenterol. 1997;32:127\u2013133.","journal-title":"J Gastroenterol"},{"key":"2587_CR3","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0016-5085(97)70225-7","volume":"112","author":"BK Reuter","year":"1997","unstructured":"Reuter BK, Davies NM, Wallace JL. Nonsteroidal anti-inflammatory drug enteropathy in rats: role of permeability, bacteria, and enterohepatic circulation. Gastroenterology. 1997;112:109\u2013117.","journal-title":"Gastroenterology"},{"key":"2587_CR4","doi-asserted-by":"crossref","first-page":"G576","DOI":"10.1152\/ajpcell.1999.276.3.C576","volume":"276","author":"H Koga","year":"1999","unstructured":"Koga H, Aoyagi K, Matsumoto T, Iida M, Fujishima M. Experimental enteropathy in athymic and euthymic rats: synergistic role of lipopolysaccharide and indomethacin. Am J Physiol. 1999;276:G576\u2013G582.","journal-title":"Am J Physiol"},{"key":"2587_CR5","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1053\/gast.2000.16497","volume":"119","author":"PL Beck","year":"2000","unstructured":"Beck PL, Xavier R, Lu N, et al. Mechanisms of NSAID-induced gastrointestinal injury defined using mutant mice. Gastroenterology. 2000;119:699\u2013705.","journal-title":"Gastroenterology"},{"key":"2587_CR6","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.1016\/0016-5085(95)90708-4","volume":"108","author":"I Bjarnason","year":"1995","unstructured":"Bjarnason I, MacPherson A, Hollander D. Intestinal permeability: an overview. Gastroenterology. 1995;108:1566\u20131581.","journal-title":"Gastroenterology"},{"key":"2587_CR7","doi-asserted-by":"crossref","first-page":"1740","DOI":"10.1053\/gast.2000.20231","volume":"119","author":"EJ Irvine","year":"2000","unstructured":"Irvine EJ, Marshall JK. Increased intestinal permeability precedes the onset of Crohn\u2019s disease in a subject with familial risk. Gastroenterology. 2000;119:1740\u20131744.","journal-title":"Gastroenterology"},{"key":"2587_CR8","doi-asserted-by":"crossref","first-page":"13","DOI":"10.14712\/18059694.2019.51","volume":"45","author":"Z Cervinkova","year":"2002","unstructured":"Cervinkova Z, Radvakova D, Kohout P. Liver response to indomethacin-induced intestinal injury. Acta Med (Hradec Kralove). 2002;45:13\u201318.","journal-title":"Acta Med (Hradec Kralove)"},{"key":"2587_CR9","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1053\/gast.2002.31886","volume":"122","author":"Y Masubuchi","year":"2002","unstructured":"Masubuchi Y, Masuda E, Horie T. Multiple mechanisms in indomethacin-induced impairment of hepatic cytochrome P450 enzymes in rats. Gastroenterology. 2002;122:774\u2013783.","journal-title":"Gastroenterology"},{"key":"2587_CR10","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1248\/bpb.30.556","volume":"30","author":"N Fujiyama","year":"2007","unstructured":"Fujiyama N, Shitara Y, Ito K, Masubuchi Y, Horie T. Down-regulation of hepatic transporters for BSP in rats with indomethacin-induced intestinal injury. Biol Pharm Bull. 2007;30:556\u2013561.","journal-title":"Biol Pharm Bull"},{"key":"2587_CR11","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/S0169-409X(02)00173-4","volume":"55","author":"KN Faber","year":"2003","unstructured":"Faber KN, Muller M, Jansen PL. Drug transport proteins in the liver. Adv Drug Deliv Rev. 2003;55:107\u2013124.","journal-title":"Adv Drug Deliv Rev"},{"key":"2587_CR12","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1124\/pr.55.3.1","volume":"55","author":"N Mizuno","year":"2003","unstructured":"Mizuno N, Niwa T, Yotsumoto Y, Sugiyama Y. Impact of drug transporter studies on drug discovery and development. Pharmacol Rev. 2003;55:425\u2013461.","journal-title":"Pharmacol Rev"},{"key":"2587_CR13","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1096\/fasebj.3.1.2642868","volume":"3","author":"LJ Ignarro","year":"1989","unstructured":"Ignarro LJ. Endothelium-derived nitric oxide: actions and properties. FASEB J. 1989;3:31\u201336.","journal-title":"FASEB J"},{"key":"2587_CR14","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1023\/A:1015926119947","volume":"6","author":"LJ Ignarro","year":"1989","unstructured":"Ignarro LJ. Endothelium-derived nitric oxide: pharmacology and relationship to the actions of organic nitrate esters. Pharm Res. 1989;6:651\u2013659.","journal-title":"Pharm Res"},{"key":"2587_CR15","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1007\/s10787-007-0013-x","volume":"15","author":"JN Sharma","year":"2007","unstructured":"Sharma JN, Al-Omran A, Parvathy SS. Role of nitric oxide in inflammatory diseases. Inflammopharmacology. 2007;15:252\u2013259.","journal-title":"Inflammopharmacology"},{"key":"2587_CR16","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/S0014-2999(01)01327-9","volume":"429","author":"SM Evans","year":"2001","unstructured":"Evans SM, Whittle BJ. Interactive roles of superoxide and inducible nitric oxide synthase in rat intestinal injury provoked by non-steroidal anti-inflammatory drugs. Eur J Pharmacol. 2001;429:287\u2013296.","journal-title":"Eur J Pharmacol"},{"key":"2587_CR17","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S0304-4165(02)00480-4","volume":"1619","author":"TE Akiyama","year":"2003","unstructured":"Akiyama TE, Gonzalez FJ. Regulation of P450 genes by liver-enriched transcription factors and nuclear receptors. Biochim Biophys Acta. 2003;1619:223\u2013234.","journal-title":"Biochim Biophys Acta"},{"key":"2587_CR18","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1038\/nm815","volume":"9","author":"RG Tirona","year":"2003","unstructured":"Tirona RG, Lee W, Leake BF, et al. The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4. Nat Med. 2003;9:220\u2013224.","journal-title":"Nat Med"},{"key":"2587_CR19","doi-asserted-by":"crossref","first-page":"8835","DOI":"10.1074\/jbc.275.12.8835","volume":"275","author":"LA Denson","year":"2000","unstructured":"Denson LA, Auld KL, Schiek DS, McClure MH, Mangelsdorf DJ, Karpen SJ. Interleukin-1beta suppresses retinoid transactivation of two hepatic transporter genes involved in bile formation. J Biol Chem. 2000;275:8835\u20138843.","journal-title":"J Biol Chem"},{"key":"2587_CR20","doi-asserted-by":"crossref","first-page":"2908","DOI":"10.1074\/jbc.M109326200","volume":"277","author":"HR Kast","year":"2002","unstructured":"Kast HR, Goodwin B, Tarr PT, et al. Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor. J Biol Chem. 2002;277:2908\u20132915.","journal-title":"J Biol Chem"},{"key":"2587_CR21","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1053\/gast.2002.34758","volume":"123","author":"LA Denson","year":"2002","unstructured":"Denson LA, Bohan A, Held MA, Boyer JL. Organ-specific alterations in RAR alpha:RXR alpha abundance regulate rat Mrp2 (Abcc2) expression in obstructive cholestasis. Gastroenterology. 2002;123:599\u2013607.","journal-title":"Gastroenterology"},{"key":"2587_CR22","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1124\/jpet.301.2.551","volume":"301","author":"N Li","year":"2002","unstructured":"Li N, Hartley DP, Cherrington NJ, Klaassen CD. Tissue expression, ontogeny, and inducibility of rat organic anion transporting polypeptide 4. J Pharmacol Exp Ther. 2002;301:551\u2013560.","journal-title":"J Pharmacol Exp Ther"},{"key":"2587_CR23","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1124\/jpet.300.1.206","volume":"300","author":"GL Guo","year":"2002","unstructured":"Guo GL, Choudhuri S, Klaassen CD. Induction profile of rat organic anion transporting polypeptide 2 (oatp2) by prototypical drug-metabolizing enzyme inducers that activate gene expression through ligand-activated transcription factor pathways. J Pharmacol Exp Ther. 2002;300:206\u2013212.","journal-title":"J Pharmacol Exp Ther"},{"key":"2587_CR24","first-page":"694","volume":"66","author":"N Li","year":"2004","unstructured":"Li N, Klaassen CD. Role of liver-enriched transcription factors in the down-regulation of organic anion transporting polypeptide 4 (oatp4; oatplb2; slc21a10) by lipopolysaccharide. Mol Pharmacol. 2004;66:694\u2013701.","journal-title":"Mol Pharmacol"},{"key":"2587_CR25","doi-asserted-by":"crossref","first-page":"1756","DOI":"10.1124\/dmd.106.010033","volume":"34","author":"E Jigorel","year":"2006","unstructured":"Jigorel E, Le Vee M, Boursier-Neyret C, Parmentier Y, Fardel O. Differential regulation of sinusoidal and canalicular hepatic drug transporter expression by xenobiotics activating drug-sensing receptors in primary human hepatocytes. Drug Metab Dispos. 2006;34:1756\u20131763.","journal-title":"Drug Metab Dispos"},{"key":"2587_CR26","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1016\/j.bcp.2003.12.012","volume":"67","author":"C Fang","year":"2004","unstructured":"Fang C, Yoon S, Tindberg N, Jarvelainen HA, Lindros KO, Ingelman-Sundberg M. Hepatic expression of multiple acute phase proteins and down-regulation of nuclear receptors after acute endotoxin exposure. Biochem Pharmacol. 2004;67:1389\u20131397. doi: 10.1016\/j.bcp.2003.12.012 .","journal-title":"Biochem Pharmacol"},{"key":"2587_CR27","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1016\/S0024-3205(02)01795-2","volume":"71","author":"F Gao","year":"2002","unstructured":"Gao F, Horie T. A synthetic analog of prostaglandin E(1) prevents the production of reactive oxygen species in the intestinal mucosa of methotrexate-treated rats. Life Sci. 2002;71:1091\u20131099.","journal-title":"Life Sci"},{"key":"2587_CR28","doi-asserted-by":"crossref","first-page":"G42","DOI":"10.1152\/ajpgi.00416.2003","volume":"287","author":"K Ito","year":"2004","unstructured":"Ito K, Koresawa T, Nakano K, Horie T. Mrp2 is involved in benzylpenicillin-induced choleresis. Am J Physiol Gastrointest Liver Physiol. 2004;287:G42\u2013G49.","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"2587_CR29","doi-asserted-by":"crossref","first-page":"3209","DOI":"10.1002\/(SICI)1521-3773(19991102)38:21<3209::AID-ANIE3209>3.0.CO;2-6","volume":"38","author":"H Kojima","year":"1999","unstructured":"Kojima H, Urano Y, Kikuchi K, Higuchi T, Hirata Y, Nagano T. Fluorescent indicators for imaging nitric oxide production. Angew Chem Int Ed Engl. 1999;38:3209\u20133212.","journal-title":"Angew Chem Int Ed Engl"},{"key":"2587_CR30","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1053\/j.gastro.2008.06.006","volume":"135","author":"K Geddes","year":"2008","unstructured":"Geddes K, Philpott DJ. A new role for intestinal alkaline phosphatase in gut barrier maintenance. Gastroenterology. 2008;135:8\u201312.","journal-title":"Gastroenterology"},{"key":"2587_CR31","doi-asserted-by":"crossref","first-page":"G804","DOI":"10.1152\/ajpcell.1996.270.4.C1096","volume":"270","author":"T Yamada","year":"1996","unstructured":"Yamada T, Hoshino M, Hayakawa T, et al. Bile secretion in rats with indomethacin-induced intestinal inflammation. Am J Physiol. 1996;270:G804\u2013G812.","journal-title":"Am J Physiol"},{"key":"2587_CR32","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1124\/dmd.32.7.734","volume":"32","author":"NJ Cherrington","year":"2004","unstructured":"Cherrington NJ, Slitt AL, Li N, Klaassen CD. Lipopolysaccharide-mediated regulation of hepatic transporter mRNA levels in rats. Drug Metab Dispos. 2004;32:734\u2013741.","journal-title":"Drug Metab Dispos"},{"key":"2587_CR33","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1248\/bpb.31.412","volume":"31","author":"K Aoki","year":"2008","unstructured":"Aoki K, Nakajima M, Hoshi Y, et al. Effect of aminoguanidine on lipopolysaccharide-induced changes in rat liver transporters and transcription factors. Biol Pharm Bull. 2008;31:412\u2013420.","journal-title":"Biol Pharm Bull"},{"key":"2587_CR34","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1093\/toxsci\/kfm261","volume":"101","author":"Y Tanaka","year":"2008","unstructured":"Tanaka Y, Chen C, Maher JM, Klaassen CD. Ischemia-reperfusion of rat livers decreases liver and increases kidney multidrug resistance associated protein 2 (Mrp2). Toxicol Sci. 2008;101:171\u2013178. doi: 10.1093\/toxsci\/kfm261 .","journal-title":"Toxicol Sci"},{"key":"2587_CR35","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1038\/labinvest.2009.104","volume":"90","author":"LM Lopez-Sanchez","year":"2010","unstructured":"Lopez-Sanchez LM, Corrales FJ, Barcos M, Espejo I, Munoz-Castaneda JR, Rodriguez-Ariza A. Inhibition of nitric oxide synthesis during induced cholestasis ameliorates hepatocellular injury by facilitating S-nitrosothiol homeostasis. Lab Invest. 2010;90:116\u2013127. doi: 10.1038\/labinvest.2009.104 .","journal-title":"Lab Invest"}],"container-title":["Digestive Diseases and Sciences"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-013-2587-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10620-013-2587-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-013-2587-z","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,9]],"date-time":"2019-07-09T23:53:07Z","timestamp":1562716387000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10620-013-2587-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2,27]]},"references-count":35,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2013,7]]}},"alternative-id":["2587"],"URL":"https:\/\/doi.org\/10.1007\/s10620-013-2587-z","relation":{},"ISSN":["0163-2116","1573-2568"],"issn-type":[{"value":"0163-2116","type":"print"},{"value":"1573-2568","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,2,27]]}}}