{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T18:33:48Z","timestamp":1790620428701,"version":"4.1.0"},"reference-count":53,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2013,7,2]],"date-time":"2013-07-02T00:00:00Z","timestamp":1372723200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dig Dis Sci"],"published-print":{"date-parts":[[2013,10]]},"DOI":"10.1007\/s10620-013-2767-x","type":"journal-article","created":{"date-parts":[[2013,7,1]],"date-time":"2013-07-01T08:47:08Z","timestamp":1372668428000},"page":"2777-2783","source":"Crossref","is-referenced-by-count":17,"title":["Helicobacter pylori and Gastritis: The Role of Extracellular Matrix Metalloproteases, Their Inhibitors, and the Disintegrins and Metalloproteases\u2014A Systematic Literature Review"],"prefix":"10.1007","volume":"58","author":[{"given":"Clara L.","family":"Sampieri","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,7,2]]},"reference":[{"key":"2767_CR1","first-page":"426","volume":"118","author":"W Bartnik","year":"2008","unstructured":"Bartnik W. Clinical aspects of Helicobacter pylori infection. Pol Arch Med Wewn. 2008;118:426\u2013430.","journal-title":"Pol Arch Med Wewn"},{"key":"2767_CR2","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1002\/jcb.21375","volume":"102","author":"P Vogiatzi","year":"2007","unstructured":"Vogiatzi P, Cassone M, Luzzi I, et al. Helicobacter pylori as a class I carcinogen: physiopathology and management strategies. J Cell Biochem. 2007;102:264\u2013273.","journal-title":"J Cell Biochem"},{"key":"2767_CR3","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1111\/j.1349-7006.2005.00130.x","volume":"96","author":"M Hatakeyama","year":"2005","unstructured":"Hatakeyama M, Higashi H. Helicobacter pylori CagA: a new paradigm for bacterial carcinogenesis. Cancer Sci. 2005;96:835\u2013843.","journal-title":"Cancer Sci"},{"key":"2767_CR4","doi-asserted-by":"crossref","first-page":"9999","DOI":"10.1073\/pnas.0603784103","volume":"103","author":"JD Oh","year":"2006","unstructured":"Oh JD, Kling-Backhed H, Giannakis M, et al. The complete genome sequence of a chronic atrophic gastritis Helicobacter pylori strain: evolution during disease progression. Proc Natl Acad Sci USA. 2006;103:9999\u201310004.","journal-title":"Proc Natl Acad Sci USA"},{"key":"2767_CR5","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1136\/gut.40.6.701","volume":"40","author":"JC Atherton","year":"1997","unstructured":"Atherton JC. The clinical relevance of strain types of Helicobacter pylori. Gut. 1997;40:701\u2013703.","journal-title":"Gut"},{"key":"2767_CR6","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/0140-6736(91)90477-7","volume":"338","author":"JE Crabtree","year":"1991","unstructured":"Crabtree JE, Taylor JD, Wyatt JI, et al. Mucosal IgA recognition of Helicobacter pylori 120\u00a0kDa protein, peptic ulceration, and gastric pathology. Lancet. 1991;338:332\u2013335.","journal-title":"Lancet"},{"key":"2767_CR7","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1016\/j.biocel.2007.12.006","volume":"40","author":"IM Clark","year":"2008","unstructured":"Clark IM, Swingler TE, Sampieri CL, et al. The regulation of matrix metalloproteinases and their inhibitors. Int J Biochem Cell Biol. 2008;40:1362\u20131378.","journal-title":"Int J Biochem Cell Biol"},{"key":"2767_CR8","doi-asserted-by":"crossref","first-page":"3719","DOI":"10.1242\/jcs.00063","volume":"115","author":"AH Baker","year":"2002","unstructured":"Baker AH, Edwards DR, Murphy G. Metalloproteinase inhibitors: biological actions and therapeutic opportunities. J Cell Sci. 2002;115:3719\u20133727.","journal-title":"J Cell Sci"},{"key":"2767_CR9","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.mam.2008.08.001","volume":"29","author":"DR Edwards","year":"2008","unstructured":"Edwards DR, Handsley MM, Pennington CJ. The ADAM metalloproteinases. Mol Aspects Med. 2008;29:258\u2013289.","journal-title":"Mol Aspects Med"},{"key":"2767_CR10","doi-asserted-by":"crossref","first-page":"34651","DOI":"10.1074\/jbc.M604574200","volume":"281","author":"P Kundu","year":"2006","unstructured":"Kundu P, Mukhopadhyay AK, Patra R, et al. Cag pathogenicity island-independent up-regulation of matrix metalloproteinases-9 and -2 secretion and expression in mice by Helicobacter pylori infection. J Biol Chem. 2006;281:34651\u201334662.","journal-title":"J Biol Chem"},{"key":"2767_CR11","doi-asserted-by":"crossref","first-page":"2868","DOI":"10.1074\/jbc.M511053200","volume":"281","author":"S Krueger","year":"2006","unstructured":"Krueger S, Hundertmark T, Kalinski T, et al. Helicobacter pylori encoding the pathogenicity island activates matrix metalloproteinase 1 in gastric epithelial cells via JNK and ERK. J Biol Chem. 2006;281:2868\u20132875.","journal-title":"J Biol Chem"},{"key":"2767_CR12","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1038\/nrc745","volume":"2","author":"M Egeblad","year":"2002","unstructured":"Egeblad M, Werb Z. New functions for the matrix metalloproteinases in cancer progression. Nat Rev Cancer. 2002;2:161\u2013174.","journal-title":"Nat Rev Cancer"},{"key":"2767_CR13","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1517\/13543784.14.6.591","volume":"14","author":"BB Zhou","year":"2005","unstructured":"Zhou BB, Fridman JS, Liu X, et al. ADAM proteases, ErbB pathways and cancer. Expert Opin Investig Drugs. 2005;14:591\u2013606.","journal-title":"Expert Opin Investig Drugs"},{"key":"2767_CR14","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/2046-4053-2-4","volume":"2","author":"A Booth","year":"2013","unstructured":"Booth A, Clarke M, Dooley G, et al. PROSPERO at one year: an evaluation of its utility. Syst Rev. 2013;2:4\u201311.","journal-title":"Syst Rev"},{"key":"2767_CR15","doi-asserted-by":"crossref","first-page":"5111","DOI":"10.1158\/0008-5472.CAN-06-0383","volume":"66","author":"JY Wu","year":"2006","unstructured":"Wu JY, Lu H, Sun Y, et al. Balance between polyoma enhancing activator 3 and activator protein 1 regulates Helicobacter pylori-stimulated matrix metalloproteinase 1 expression. Cancer Res. 2006;66:5111\u20135120.","journal-title":"Cancer Res"},{"key":"2767_CR16","doi-asserted-by":"crossref","unstructured":"Sokolova O, Vieth M, Naumann M. Protein kinase C isozymes regulate matrix metalloproteinase-1 expression and cell invasion in Helicobacter pylori infection. Gut. 2013;62:358\u2013367.","DOI":"10.1136\/gutjnl-2012-302103"},{"key":"2767_CR17","doi-asserted-by":"crossref","first-page":"G823","DOI":"10.1152\/ajpgi.2001.281.3.G823","volume":"281","author":"M Gooz","year":"2001","unstructured":"Gooz M, Gooz P, Smolka AJ. Epithelial and bacterial metalloproteinases and their inhibitors in H. pylori infection of human gastric cells. Am J Physiol Gastrointest Liver Physiol. 2001;281:G823\u2013G832.","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"2767_CR18","doi-asserted-by":"crossref","first-page":"18722","DOI":"10.1074\/jbc.M703022200","volume":"282","author":"MH Pillinger","year":"2007","unstructured":"Pillinger MH, Marjanovic N, Kim SY, et al. Helicobacter pylori stimulates gastric epithelial cell MMP-1 secretion via CagA-dependent and -independent ERK activation. J Biol Chem. 2007;282:18722\u201318731.","journal-title":"J Biol Chem"},{"key":"2767_CR19","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1111\/j.1083-4389.2004.00232.x","volume":"9","author":"PJ Bergin","year":"2004","unstructured":"Bergin PJ, Anders E, Sicheng W, et al. Increased production of matrix metalloproteinases in Helicobacter pylori-associated human gastritis. Helicobacter. 2004;9:201\u2013210.","journal-title":"Helicobacter"},{"key":"2767_CR20","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1111\/j.1523-5378.2007.00527.x","volume":"12","author":"FJ Kubben","year":"2007","unstructured":"Kubben FJ, Sier CF, Schram MT, et al. Eradication of Helicobacter pylori infection favourably affects altered gastric mucosal MMP-9 levels. Helicobacter. 2007;12:498\u2013504.","journal-title":"Helicobacter"},{"key":"2767_CR21","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1080\/07853890802482452","volume":"41","author":"HI Rautelin","year":"2009","unstructured":"Rautelin HI, Oksanen AM, Veijola LI, et al. Enhanced systemic matrix metalloproteinase response in Helicobacter pylori gastritis. Ann Med. 2009;41:208\u2013215.","journal-title":"Ann Med"},{"key":"2767_CR22","doi-asserted-by":"crossref","first-page":"492","DOI":"10.3109\/00365513.2010.520732","volume":"70","author":"H Rautelin","year":"2010","unstructured":"Rautelin H, Tervahartiala T, Lauhio A, et al. Assessment of systemic matrix metalloproteinase and their regulator response in children with Helicobacter pylori gastritis. Scand J Clin Lab Invest. 2010;70:492\u2013496.","journal-title":"Scand J Clin Lab Invest"},{"key":"2767_CR23","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.1007\/s10620-009-0926-x","volume":"55","author":"YC Yeh","year":"2010","unstructured":"Yeh YC, Sheu BS, Cheng HC, et al. Elevated serum matrix metalloproteinase-3 and -7 in H. pylori-related gastric cancer can be biomarkers correlating with a poor survival. Dig Dis Sci. 2010;55:1649\u20131657.","journal-title":"Dig Dis Sci"},{"key":"2767_CR24","doi-asserted-by":"crossref","first-page":"5957","DOI":"10.4049\/jimmunol.178.9.5957","volume":"178","author":"R Caruso","year":"2007","unstructured":"Caruso R, Fina D, Peluso I, et al. IL-21 is highly produced in Helicobacter pylori-infected gastric mucosa and promotes gelatinases synthesis. J Immunol. 2007;178:5957\u20135965.","journal-title":"J Immunol"},{"key":"2767_CR25","doi-asserted-by":"crossref","first-page":"34888","DOI":"10.1074\/jbc.M607067200","volume":"281","author":"MJ Oliveira","year":"2006","unstructured":"Oliveira MJ, Costa AC, Costa AM, et al. Helicobacter pylori induces gastric epithelial cell invasion in a c-Met and type IV secretion system-dependent manner. J Biol Chem. 2006;281:34888\u201334896.","journal-title":"J Biol Chem"},{"key":"2767_CR26","doi-asserted-by":"crossref","first-page":"3197","DOI":"10.3748\/wjg.v11.i21.3197","volume":"11","author":"CY Wu","year":"2005","unstructured":"Wu CY, Wang CJ, Tseng CC, et al. Helicobacter pylori promote gastric cancer cells invasion through a NF-kappaB and COX-2-mediated pathway. World J Gastroenterol. 2005;11:3197\u20133203.","journal-title":"World J Gastroenterol"},{"key":"2767_CR27","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1111\/j.1523-5378.2011.00851.x","volume":"16","author":"YH Nam","year":"2011","unstructured":"Nam YH, Ryu E, Lee D, et al. CagA phosphorylation-dependent MMP-9 expression in gastric epithelial cells. Helicobacter. 2011;16:276\u2013283.","journal-title":"Helicobacter"},{"key":"2767_CR28","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1111\/j.1574-695X.2007.00349.x","volume":"52","author":"PJ Bergin","year":"2008","unstructured":"Bergin PJ, Raghavan S, Svensson H, et al. Gastric gelatinase B\/matrix metalloproteinase-9 is rapidly increased in Helicobacter felis-induced gastritis. FEMS Immunol Med Microbiol. 2008;52:88\u201398.","journal-title":"FEMS Immunol Med Microbiol"},{"key":"2767_CR29","doi-asserted-by":"crossref","first-page":"e16306","DOI":"10.1371\/journal.pone.0016306","volume":"6","author":"P Kundu","year":"2011","unstructured":"Kundu P, De R, Pal I, et al. Curcumin alleviates matrix metalloproteinase-3 and -9 activities during eradication of Helicobacter pylori infection in cultured cells and mice. PLoS ONE. 2011;6:e16306.","journal-title":"PLoS ONE"},{"key":"2767_CR30","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1007\/s00726-010-0689-x","volume":"41","author":"T Klein","year":"2011","unstructured":"Klein T, Bischoff R. Physiology and pathophysiology of matrix metalloproteases. Amino Acids. 2011;41:271\u2013290.","journal-title":"Amino Acids"},{"key":"2767_CR31","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1136\/jcp.2007.048058","volume":"61","author":"K Bodger","year":"2008","unstructured":"Bodger K, Ahmed S, Pazmany L, et al. Altered gastric corpus expression of tissue inhibitors of metalloproteinases in human and murine Helicobacter infection. J Clin Pathol. 2008;61:72\u201378.","journal-title":"J Clin Pathol"},{"key":"2767_CR32","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1080\/00365520802130209","volume":"43","author":"YW Chang","year":"2008","unstructured":"Chang YW, Oh HC, Jang JY, et al. IL-1beta and IL-8, matrix metalloproteinase 3, and pepsinogen secretion before and after H. pylori eradication in gastroduodenal phenotypes. Scand J Gastroenterol. 2008;43:1184\u20131193.","journal-title":"Scand J Gastroenterol"},{"key":"2767_CR33","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1136\/gut.52.9.1250","volume":"52","author":"M Gooz","year":"2003","unstructured":"Gooz M, Shaker M, Gooz P, et al. Interleukin 1beta induces gastric epithelial cell matrix metalloproteinase secretion and activation during Helicobacter pylori infection. Gut. 2003;52:1250\u20131256.","journal-title":"Gut"},{"key":"2767_CR34","doi-asserted-by":"crossref","first-page":"41417","DOI":"10.1074\/jbc.M107121200","volume":"276","author":"YS Lopez-Boado","year":"2001","unstructured":"Lopez-Boado YS, Wilson CL, Parks WC. Regulation of matrilysin expression in airway epithelial cells by Pseudomonas aeruginosa flagellin. J Biol Chem. 2001;276:41417\u201341423.","journal-title":"J Biol Chem"},{"key":"2767_CR35","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1038\/nrc703","volume":"2","author":"RM Peek Jr","year":"2002","unstructured":"Peek RM Jr, Blaser MJ. Helicobacter pylori and gastrointestinal tract adenocarcinomas. Nat Rev Cancer. 2002;2:28\u201337.","journal-title":"Nat Rev Cancer"},{"key":"2767_CR36","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1136\/gut.2009.199794","volume":"59","author":"Y Yin","year":"2010","unstructured":"Yin Y, Grabowska AM, Clarke PA, et al. Helicobacter pylori potentiates epithelial:mesenchymal transition in gastric cancer: links to soluble HB-EGF, gastrin and matrix metalloproteinase-7. Gut. 2010;59:1037\u20131045.","journal-title":"Gut"},{"key":"2767_CR37","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1016\/S0016-5085(03)01206-X","volume":"125","author":"HC Crawford","year":"2003","unstructured":"Crawford HC, Krishna US, Israel DA, et al. Helicobacter pylori strain-selective induction of matrix metalloproteinase-7 in vitro and within gastric mucosa. Gastroenterology. 2003;125:1125\u20131136.","journal-title":"Gastroenterology"},{"key":"2767_CR38","doi-asserted-by":"crossref","first-page":"3017","DOI":"10.1242\/jcs.00518","volume":"116","author":"LE Wroblewski","year":"2003","unstructured":"Wroblewski LE, Noble PJ, Pagliocca A, et al. Stimulation of MMP-7 (matrilysin) by Helicobacter pylori in human gastric epithelial cells: role in epithelial cell migration. J Cell Sci. 2003;116:3017\u20133026.","journal-title":"J Cell Sci"},{"key":"2767_CR39","doi-asserted-by":"crossref","first-page":"1754","DOI":"10.1053\/j.gastro.2006.02.031","volume":"130","author":"C McCaig","year":"2006","unstructured":"McCaig C, Duval C, Hemers E, et al. The role of matrix metalloproteinase-7 in redefining the gastric microenvironment in response to Helicobacter pylori. Gastroenterology. 2006;130:1754\u20131763.","journal-title":"Gastroenterology"},{"key":"2767_CR40","doi-asserted-by":"crossref","first-page":"4110","DOI":"10.1091\/mbc.E08-03-0283","volume":"19","author":"SR Ogden","year":"2008","unstructured":"Ogden SR, Wroblewski LE, Weydig C, et al. p120 and Kaiso regulate Helicobacter pylori-induced expression of matrix metalloproteinase-7. Mol Biol Cell. 2008;19:4110\u20134121.","journal-title":"Mol Biol Cell"},{"key":"2767_CR41","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1089\/dna.2008.0842","volume":"28","author":"BR Achyut","year":"2009","unstructured":"Achyut BR, Ghoshal UC, Moorchung N, et al. Transforming growth factor-B1 and matrix metalloproteinase-7 promoter variants induce risk for Helicobacter pylori-associated gastric precancerous lesions. DNA Cell Biol. 2009;28:295\u2013301.","journal-title":"DNA Cell Biol"},{"key":"2767_CR42","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1158\/0008-5472.CAN-09-2899","volume":"70","author":"SR Ogden","year":"2010","unstructured":"Ogden SR, Noto JM, Allen SS, et al. Matrix metalloproteinase-7 and premalignant host responses in Helicobacter pylori-infected mice. Cancer Res. 2010;70:30\u201335.","journal-title":"Cancer Res"},{"key":"2767_CR43","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1080\/00365520410003245","volume":"39","author":"S Koyama","year":"2004","unstructured":"Koyama S. Significance of cell-surface expression of matrix metalloproteinases and their inhibitors on gastric epithelium and infiltrating mucosal lymphocytes in progression of Helicobacter pylori-associated gastritis. Scand J Gastroenterol. 2004;39:1046\u20131053.","journal-title":"Scand J Gastroenterol"},{"key":"2767_CR44","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1086\/338191","volume":"185","author":"T Yoshimura","year":"2002","unstructured":"Yoshimura T, Tomita T, Dixon MF, et al. ADAMs (a disintegrin and metalloproteinase) messenger RNA expression in Helicobacter pylori-infected, normal, and neoplastic gastric mucosa. J Infect Dis. 2002;185:332\u2013340.","journal-title":"J Infect Dis"},{"key":"2767_CR45","doi-asserted-by":"crossref","first-page":"3500","DOI":"10.1016\/j.yexcr.2009.07.029","volume":"315","author":"W Schirrmeister","year":"2009","unstructured":"Schirrmeister W, Gnad T, Wex T, et al. Ectodomain shedding of E-cadherin and c-Met is induced by Helicobacter pylori infection. Exp Cell Res. 2009;315:3500\u20133508.","journal-title":"Exp Cell Res"},{"key":"2767_CR46","unstructured":"Yan F, Cao H, Chaturvedi R, et al. Epidermal growth factor receptor activation protects gastric epithelial cells from Helicobacter pylori-induced apoptosis. Gastroenterology. 2009;136:1297\u20131307, e1\u2013e3."},{"key":"2767_CR47","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1053\/j.gastro.2010.03.036","volume":"139","author":"A Saha","year":"2010","unstructured":"Saha A, Backert S, Hammond CE, et al. Helicobacter pylori CagL activates ADAM17 to induce repression of the gastric H, K-ATPase alpha subunit. Gastroenterology. 2010;139:239\u2013248.","journal-title":"Gastroenterology"},{"key":"2767_CR48","unstructured":"IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Schistosomes, liver flukes and Helicobacter pylori. Lyon, 7\u201314 June 1994. IARC Monogr Eval Carcinog Risks Hum. 1994;61:1\u2013241."},{"key":"2767_CR49","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1007\/PL00011698","volume":"3","author":"Y Yonemura","year":"2000","unstructured":"Yonemura Y, Endou Y, Fujita H, et al. Role of MMP-7 in the formation of peritoneal dissemination in gastric cancer. Gastric Cancer. 2000;3:63\u201370.","journal-title":"Gastric Cancer"},{"key":"2767_CR50","doi-asserted-by":"crossref","unstructured":"Xing X, Tang YB, Yuan G, et al. The prognostic value of E-cadherin in gastric cancer: a meta-analysis. Int J Cancer. 2013;132:2589\u20132596.","DOI":"10.1002\/ijc.27947"},{"key":"2767_CR51","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1053\/j.gastro.2006.04.031","volume":"131","author":"L Friis-Hansen","year":"2006","unstructured":"Friis-Hansen L, Rieneck K, Nilsson HO, et al. Gastric inflammation, metaplasia, and tumor development in gastrin-deficient mice. Gastroenterology. 2006;131:246\u2013258.","journal-title":"Gastroenterology"},{"key":"2767_CR52","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1186\/1741-7015-10-51","volume":"10","author":"DG Altman","year":"2012","unstructured":"Altman DG, McShane LM, Sauerbrei W, et al. Reporting recommendations for tumor marker prognostic studies (REMARK): explanation and elaboration. BMC Med. 2012;10:51.","journal-title":"BMC Med"},{"key":"2767_CR53","doi-asserted-by":"crossref","first-page":"3429","DOI":"10.1021\/pr200021n","volume":"10","author":"HM Moore","year":"2012","unstructured":"Moore HM, Kelly AB, Jewell SD, et al. Biospecimen reporting for improved study quality (BRISQ). J Proteome Res. 2012;10:3429\u20133438.","journal-title":"J Proteome Res"}],"container-title":["Digestive Diseases and Sciences"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-013-2767-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10620-013-2767-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-013-2767-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,16]],"date-time":"2019-07-16T17:12:52Z","timestamp":1563297172000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10620-013-2767-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7,2]]},"references-count":53,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2013,10]]}},"alternative-id":["2767"],"URL":"https:\/\/doi.org\/10.1007\/s10620-013-2767-x","relation":{},"ISSN":["0163-2116","1573-2568"],"issn-type":[{"value":"0163-2116","type":"print"},{"value":"1573-2568","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7,2]]}}}