{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,5]],"date-time":"2025-04-05T22:05:29Z","timestamp":1743890729446},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2015,7,22]],"date-time":"2015-07-22T00:00:00Z","timestamp":1437523200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"Korean Health Technology R&D Project","award":["A111428, A120176"],"award-info":[{"award-number":["A111428, A120176"]}]},{"name":"Ministry of Health & Welfare, Republic of Korea","award":["HI13C1345"],"award-info":[{"award-number":["HI13C1345"]}]},{"name":"faculty research grant of Yonsei University College of Medicine for 2012","award":["6-2012-0135"],"award-info":[{"award-number":["6-2012-0135"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Dig Dis Sci"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1007\/s10620-015-3799-1","type":"journal-article","created":{"date-parts":[[2015,7,21]],"date-time":"2015-07-21T00:14:26Z","timestamp":1437437666000},"page":"3721-3727","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Postoperative Effects of Thiopurines in Patients with Intestinal Beh\u00e7et\u2019s Disease"],"prefix":"10.1007","volume":"60","author":[{"given":"Hye Won","family":"Lee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jae Hee","family":"Cheon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyun Jung","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soo Jung","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung Pil","family":"Hong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tae Il","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Won Ho","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2015,7,22]]},"reference":[{"key":"3799_CR1","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1007\/s00535-007-2090-4","volume":"42","author":"K Kobayashi","year":"2007","unstructured":"Kobayashi K, Ueno F, Bito S, et al. Development of consensus statements for the diagnosis and management of intestinal Behcet\u2019s disease using a modified Delphi approach. J Gastroenterol. 2007;42:737\u2013745.","journal-title":"J Gastroenterol"},{"key":"3799_CR2","doi-asserted-by":"crossref","first-page":"2904","DOI":"10.1007\/s10620-009-1095-7","volume":"55","author":"CM Moon","year":"2010","unstructured":"Moon CM, Cheon JH, Shin JK, et al. Prediction of free bowel perforation in patients with intestinal Behcet\u2019s disease using clinical and colonoscopic findings. Dig Dis Sci. 2010;55:2904\u20132911.","journal-title":"Dig Dis Sci"},{"key":"3799_CR3","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1097\/00004836-200003000-00006","volume":"30","author":"Y Bayraktar","year":"2000","unstructured":"Bayraktar Y, Ozaslan E, Van Thiel DH. Gastrointestinal manifestations of Behcet\u2019s disease. J Clin Gastroenterol. 2000;30:144\u2013154.","journal-title":"J Clin Gastroenterol"},{"key":"3799_CR4","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/s10620-008-0337-4","volume":"54","author":"EC Ebert","year":"2009","unstructured":"Ebert EC. Gastrointestinal manifestations of Behcet\u2019s disease. Dig Dis Sci. 2009;54:201\u2013207.","journal-title":"Dig Dis Sci"},{"key":"3799_CR5","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1002\/ibd.21757","volume":"18","author":"YS Jung","year":"2012","unstructured":"Jung YS, Cheon JH, Hong SP, et al. Clinical outcomes and prognostic factors for thiopurine maintenance therapy in patients with intestinal Behcet\u2019s disease. Inflamm Bowel Dis. 2012;18:750\u2013757.","journal-title":"Inflamm Bowel Dis"},{"key":"3799_CR6","doi-asserted-by":"crossref","first-page":"155","DOI":"10.5217\/ir.2013.11.3.155","volume":"11","author":"HW Lee","year":"2013","unstructured":"Lee HW, Kim WH, Cheon JH. The medical treatments of intestinal Beh\u00e7et\u2019s disease: an update. Intest Res. 2013;11:155\u2013160.","journal-title":"Intest Res"},{"key":"3799_CR7","first-page":"81","volume":"38","author":"I Sayek","year":"1991","unstructured":"Sayek I, Aran O, Uzunalimoglu B, et al. Intestinal Behcet\u2019s disease: surgical experience in seven cases. Hepatogastroenterology. 1991;38:81\u201383.","journal-title":"Hepatogastroenterology"},{"key":"3799_CR8","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1001\/archsurg.1980.01380060057016","volume":"115","author":"LL Ketch","year":"1980","unstructured":"Ketch LL, Buerk CA, Liechty D. Surgical implications of Behcet\u2019s disease. Arch Surg. 1980;115:759\u2013760.","journal-title":"Arch Surg"},{"key":"3799_CR9","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1097\/BOR.0000000000000125","volume":"27","author":"JH Cheon","year":"2015","unstructured":"Cheon JH, Kim WH. An update on the diagnosis, treatment, and prognosis of intestinal Behcet\u2019s disease. Curr Opin Rheumatol. 2015;27:24\u201331.","journal-title":"Curr Opin Rheumatol"},{"key":"3799_CR10","doi-asserted-by":"crossref","first-page":"1594","DOI":"10.1002\/ibd.21517","volume":"17","author":"YS Jung","year":"2011","unstructured":"Jung YS, Yoon JY, Lee JH, et al. Prognostic factors and long-term clinical outcomes for surgical patients with intestinal Behcet\u2019s disease. Inflamm Bowel Dis. 2011;17:1594\u20131602.","journal-title":"Inflamm Bowel Dis"},{"key":"3799_CR11","unstructured":"Pearson DC, May GR, Fick G, et al. Azathioprine for maintaining remission of Crohn\u2019s disease. Cochrane Database Syst Rev. 2000:Cd000067."},{"key":"3799_CR12","doi-asserted-by":"crossref","first-page":"2089","DOI":"10.1038\/ajg.2009.301","volume":"104","author":"L Peyrin-Biroulet","year":"2009","unstructured":"Peyrin-Biroulet L, Deltenre P, Ardizzone S, et al. Azathioprine and 6-mercaptopurine for the prevention of postoperative recurrence in Crohn\u2019s disease: a meta-analysis. Am J Gastroenterol. 2009;104:2089\u20132096.","journal-title":"Am J Gastroenterol"},{"key":"3799_CR13","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1007\/BF02235590","volume":"43","author":"IJ Choi","year":"2000","unstructured":"Choi IJ, Kim JS, Cha SD, et al. Long-term clinical course and prognostic factors in intestinal Behcet\u2019s disease. Dis Colon Rectum. 2000;43:692\u2013700.","journal-title":"Dis Colon Rectum"},{"key":"3799_CR14","doi-asserted-by":"crossref","first-page":"2492","DOI":"10.1038\/ajg.2009.331","volume":"104","author":"JH Cheon","year":"2009","unstructured":"Cheon JH, Kim ES, Shin SJ, et al. Development and validation of novel diagnostic criteria for intestinal Behcet\u2019s disease in Korean patients with ileocolonic ulcers. Am J Gastroenterol. 2009;104:2492\u20132499.","journal-title":"Am J Gastroenterol"},{"key":"3799_CR15","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1111\/apt.12743","volume":"39","author":"GR Jones","year":"2014","unstructured":"Jones GR, Kennedy NA, Lees CW, et al. Systematic review: The use of thiopurines or anti-TNF in post-operative Crohn\u2019s disease maintenance\u2013progress and prospects. Aliment Pharmacol Ther. 2014;39:1253\u20131265.","journal-title":"Aliment Pharmacol Ther"},{"key":"3799_CR16","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1002\/ibd.21313","volume":"17","author":"JH Cheon","year":"2011","unstructured":"Cheon JH, Han DS, Park JY, et al. Development, validation, and responsiveness of a novel disease activity index for intestinal Behcet\u2019s disease. Inflamm Bowel Dis. 2011;17:605\u2013613.","journal-title":"Inflamm Bowel Dis"},{"key":"3799_CR17","first-page":"374","volume":"23","author":"P Nos","year":"2000","unstructured":"Nos P, Hinojosa J, Aguilera V, et al. Azathioprine and 5-ASA in the prevention of postoperative recurrence of Crohn\u2019s disease. Gastroenterol Hepatol. 2000;23:374\u2013378.","journal-title":"Gastroenterol Hepatol"},{"key":"3799_CR18","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1053\/j.gastro.2004.06.002","volume":"127","author":"SB Hanauer","year":"2004","unstructured":"Hanauer SB, Korelitz BI, Rutgeerts P, et al. Postoperative maintenance of Crohn\u2019s disease remission with 6-mercaptopurine, mesalamine, or placebo: a 2-year trial. Gastroenterology. 2004;127:723\u2013729.","journal-title":"Gastroenterology"},{"key":"3799_CR19","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1053\/j.gastro.2004.06.051","volume":"127","author":"S Ardizzone","year":"2004","unstructured":"Ardizzone S, Maconi G, Sampietro GM, et al. Azathioprine and mesalamine for prevention of relapse after conservative surgery for Crohn\u2019s disease. Gastroenterology. 2004;127:730\u2013740.","journal-title":"Gastroenterology"},{"key":"3799_CR20","first-page":"1525","volume":"55","author":"H Herfarth","year":"2006","unstructured":"Herfarth H, Tjaden C, Lukas M, et al. Adverse events in clinical trials with azathioprine and mesalamine for prevention of postoperative recurrence of Crohn\u2019s disease. Gut. 2006;55:1525\u20131526.","journal-title":"Gut"},{"key":"3799_CR21","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1038\/ajg.2009.673","volume":"105","author":"P Papay","year":"2010","unstructured":"Papay P, Reinisch W, Ho E, et al. The impact of thiopurines on the risk of surgical recurrence in patients with Crohn\u2019s disease after first intestinal surgery. Am J Gastroenterol. 2010;105:1158\u20131164.","journal-title":"Am J Gastroenterol"},{"key":"3799_CR22","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1097\/MIB.0000000000000119","volume":"20","author":"VC Kariyawasam","year":"2014","unstructured":"Kariyawasam VC, Selinger CP, Katelaris PH, et al. Early use of thiopurines or methotrexate reduces major abdominal and perianal surgery in Crohn\u2019s disease. Inflamm Bowel Dis. 2014;20:1382\u20131390.","journal-title":"Inflamm Bowel Dis"},{"key":"3799_CR23","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.crohns.2009.09.009","volume":"4","author":"G Assche Van","year":"2010","unstructured":"Van Assche G, Dignass A, Reinisch W, et al. The second European evidence-based Consensus on the diagnosis and management of Crohn\u2019s disease: Special situations. J Crohns Colitis. 2010;4:63\u2013101.","journal-title":"J Crohns Colitis"},{"key":"3799_CR24","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.3349\/ymj.2013.54.5.1084","volume":"54","author":"JJ Park","year":"2013","unstructured":"Park JJ, Kim WH, Cheon JH. Outcome predictors for intestinal Behcet\u2019s disease. Yonsei Med J. 2013;54:1084\u20131090.","journal-title":"Yonsei Med J"},{"key":"3799_CR25","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1053\/j.gastro.2008.07.010","volume":"135","author":"GR D\u2019Haens","year":"2008","unstructured":"D\u2019Haens GR, Vermeire S, Van Assche G, et al. Therapy of metronidazole with azathioprine to prevent postoperative recurrence of Crohn\u2019s disease: a controlled randomized trial. Gastroenterology. 2008;135:1123\u20131129.","journal-title":"Gastroenterology"},{"key":"3799_CR26","doi-asserted-by":"crossref","first-page":"1804","DOI":"10.1001\/archinte.167.16.1804","volume":"167","author":"D Sorrentino","year":"2007","unstructured":"Sorrentino D, Terrosu G, Avellini C, et al. Infliximab with low-dose methotrexate for prevention of postsurgical recurrence of ileocolonic Crohn disease. Arch Intern Med. 2007;167:1804\u20131807.","journal-title":"Arch Intern Med"},{"key":"3799_CR27","first-page":"591.e591","volume":"8","author":"D Sorrentino","year":"2010","unstructured":"Sorrentino D, Paviotti A, Terrosu G, et al. Low-dose maintenance therapy with infliximab prevents postsurgical recurrence of Crohn\u2019s disease. Clin Gastroenterol Hepatol.. 2010;8:591.e591\u2013599.e591. quiz e578\u2013e599.","journal-title":"Clin Gastroenterol Hepatol."},{"key":"3799_CR28","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1111\/j.1365-2036.2011.04577.x","volume":"33","author":"L Peyrin-Biroulet","year":"2011","unstructured":"Peyrin-Biroulet L, Oussalah A, Roblin X, et al. The use of azathioprine in Crohn\u2019s disease during pregnancy and in the post-operative setting: a worldwide survey of experts. Aliment Pharmacol Ther. 2011;33:707\u2013713.","journal-title":"Aliment Pharmacol Ther"}],"container-title":["Digestive Diseases and Sciences"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-015-3799-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10620-015-3799-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-015-3799-1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,30]],"date-time":"2019-05-30T15:49:53Z","timestamp":1559231393000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10620-015-3799-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,7,22]]},"references-count":28,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["3799"],"URL":"https:\/\/doi.org\/10.1007\/s10620-015-3799-1","relation":{},"ISSN":["0163-2116","1573-2568"],"issn-type":[{"type":"print","value":"0163-2116"},{"type":"electronic","value":"1573-2568"}],"subject":[],"published":{"date-parts":[[2015,7,22]]}}}