{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T13:17:12Z","timestamp":1762867032248,"version":"3.41.0"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2017,1,21]],"date-time":"2017-01-21T00:00:00Z","timestamp":1484956800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Dig Dis Sci"],"published-print":{"date-parts":[[2017,4]]},"DOI":"10.1007\/s10620-017-4454-9","type":"journal-article","created":{"date-parts":[[2017,1,21]],"date-time":"2017-01-21T07:05:33Z","timestamp":1484982333000},"page":"1016-1024","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Sulfasalazine in Prevention of Pouchitis After Proctocolectomy with Ileal Pouch\u2013Anal Anastomosis for Ulcerative Colitis"],"prefix":"10.1007","volume":"62","author":[{"given":"Eleonora","family":"Scaioli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Sartini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisa","family":"Liverani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard John","family":"Digby","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giampaolo","family":"Ugolini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giancarlo","family":"Rosati","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gilberto","family":"Poggioli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Davide","family":"Festi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franco","family":"Bazzoli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Belluzzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,1,21]]},"reference":[{"key":"4454_CR1","doi-asserted-by":"crossref","first-page":"4839","DOI":"10.3748\/wjg.v20.i17.4839","volume":"20","author":"G Rizzo","year":"2014","unstructured":"Rizzo G, Pugliese D, Armuzzi A, Coco C. Anti-TNF alpha in the treatment of ulcerative colitis: a valid approach for organ-sparing or an expensive option to delay surgery? World J Gastroenterol. 2014;20:4839\u20134845.","journal-title":"World J Gastroenterol"},{"key":"4454_CR2","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1038\/ajg.2012.127","volume":"107","author":"LE Targownik","year":"2012","unstructured":"Targownik LE, Singh H, Nugent Z, Bernstein CN. The epidemiology of colectomy in ulcerative colitis: results from a population-based cohort. Am J Gastroenterol. 2012;107:1228\u20131235.","journal-title":"Am J Gastroenterol"},{"key":"4454_CR3","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1016\/j.cgh.2008.05.022","volume":"6","author":"J Allison","year":"2008","unstructured":"Allison J, Herrinton LJ, Liu L, Yu J, Lowder J. Natural\u00a0history of severe ulcerative colitis in a community-based health plan. Clin Gastroenterol Hepatol. 2008;6:999\u20131003.","journal-title":"Clin Gastroenterol Hepatol"},{"key":"4454_CR4","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/0016-5085(94)90054-X","volume":"107","author":"E Langholz","year":"1994","unstructured":"Langholz E, Munkholm P, Davidsen M, Binder V. Course of ulcerative colitis: analysis of changes in disease activity over years. Gastroenterology. 1994;107:3\u201311.","journal-title":"Gastroenterology"},{"key":"4454_CR5","doi-asserted-by":"crossref","first-page":"1856","DOI":"10.1016\/0016-5085(94)90832-X","volume":"107","author":"WJ Sandborn","year":"1994","unstructured":"Sandborn WJ. Pouchitis following ileal pouch-anal anastomosis: definition, pathogenesis, and treatment. Gastroenterology. 1994;107:1856\u20131860.","journal-title":"Gastroenterology"},{"key":"4454_CR6","doi-asserted-by":"crossref","first-page":"1538","DOI":"10.1016\/j.cgh.2013.03.033","volume":"11","author":"B Shen","year":"2013","unstructured":"Shen B. Pouchitis: what every gastroenterologist needs to know. Clin Gastroenterol Hepatol. 2013;11:1538\u20131549.","journal-title":"Clin Gastroenterol Hepatol"},{"key":"4454_CR7","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1111\/j.1365-2036.2008.03643.x","volume":"27","author":"SD Mclaughlin","year":"2008","unstructured":"Mclaughlin SD, Clarks SK, Tekkis PP, Ciclitira PJ, Nicholls RJ. Review article: restorative proctocolectomy, indications, management of complications and follow-up- a guide for gastroenterologists. Aliment Pharmacol Ther. 2008;27:895\u2013909.","journal-title":"Aliment Pharmacol Ther"},{"key":"4454_CR8","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1038\/nrgastro.2012.58","volume":"9","author":"B Shen","year":"2012","unstructured":"Shen B. Acute\u00a0and chronic\u00a0pouchitis\u2013pathogenesis, diagnosis and treatment. Nat Rev Gastroenterol Hepatol. 2012;9:323\u2013333.","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"4454_CR9","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1136\/gutjnl-2011-301957","volume":"62","author":"AD Tyler","year":"2013","unstructured":"Tyler AD, Milgrom R, Stempak JM, et al. The NOD2insC polymorphism is associated with worse outcome following ileal pouch-anal anastomosis for ulcerative colitis. Gut. 2013;62:1433\u20131439.","journal-title":"Gut"},{"key":"4454_CR10","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1007\/s10350-004-6187-z","volume":"45","author":"M Duffy","year":"2002","unstructured":"Duffy M, O\u2019Mahony L, Coffey JC, et al. Sulfate\u2014reducing bacteria colonize formed for ulcerative colitis but not for familial adenomatous polyposis. Dis Col Rectum. 2002;45:384\u2013388.","journal-title":"Dis Col Rectum"},{"key":"4454_CR11","first-page":"51","volume-title":"Trends in Inflammatory Bowel Disease 1996","author":"WJ Sandborn","year":"1997","unstructured":"Sandborn WJ. Pouchitis: definition, risk factors, frequency, natural history, classification and public health perspectives. In: McLeod RS, Martin F, Sutherland LR, Wallace JL, Williams CN, eds. Trends in Inflammatory Bowel Disease 1996. Lancaster: Kluwer Academic Publishers; 1997:51\u201363."},{"key":"4454_CR12","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/S0025-6196(12)61634-6","volume":"69","author":"WJ Sandborn","year":"1994","unstructured":"Sandborn WJ, Tremaine WJ, Batts KP, Pemberton JH, Phillips SF. Pouchitis after ileal pouch\u2014anal anastomosis: a pouchitis disease activity index. Mayo Clin Pro. 1994;69:409\u2013415.","journal-title":"Mayo Clin Pro"},{"key":"4454_CR13","first-page":"CD001176","volume":"11","author":"S Singh","year":"2015","unstructured":"Singh S, Stroud AM, Holubar SD, Sandborn WJ, Pardi DS. Treatment and prevention of\u00a0pouchitis\u00a0after ileal pouch-anal anastomosis for chronic ulcerative colitis. Cochrane Database Syst Rev. 2015;11:CD001176.","journal-title":"Cochrane Database Syst Rev"},{"key":"4454_CR14","volume-title":"Goodman & Gilman\u2019s The Pharmacological Basis of Therapeutics","author":"WA Petri Jr","year":"2011","unstructured":"Petri WA Jr. Sulfonamides, trimethoprim-sulfamethoxazole, quinolones, and agents for urinary tract infections, Chapter 52. In: Brunton LL, Chabner BA, Knollmann BC, eds. Goodman & Gilman\u2019s The Pharmacological Basis of Therapeutics. 12th ed. New York: The McGraw-Hill Companies; 2011.","edition":"12"},{"key":"4454_CR15","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1111\/j.0954-6820.1942.tb06841.x","volume":"110","author":"N Svartz","year":"1942","unstructured":"Svartz N. Salazopyrin: a new sulfanilamide preparation. Acta Med Scand. 1942;110:578\u2013598.","journal-title":"Acta Med Scand"},{"key":"4454_CR16","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0140-6736(65)90972-4","volume":"i","author":"JJ Misiewicz","year":"1965","unstructured":"Misiewicz JJ, Connell AM, Lennard Jones JE, Baron JH, Avery Jones F. Controlled trial of sulphasalazine in maintenance therapy of ulcerative colitis. Lancet. 1965;i:185\u2013188.","journal-title":"Lancet"},{"key":"4454_CR17","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1111\/j.1365-2036.2009.04163.x","volume":"31","author":"A Belluzzi","year":"2010","unstructured":"Belluzzi A, Serrani M, Roda G, et al. Pilot study: the use of sulfasalazine for the treatment of acute\u00a0pouchitis. Aliment Pharmacol Ther. 2010;31:228\u2013232.","journal-title":"Aliment Pharmacol Ther"},{"key":"4454_CR18","first-page":"1474","volume-title":"Master of Surgery","author":"FH Remzi","year":"2007","unstructured":"Remzi FH, Fazio VW. Ileoanal pouch procedure for ulcerative colitis and familial adenomatous polyposis. In: Fischer JE, ed. Master of Surgery. Philadelphia: Wolters Kluwer Health\/Lippincott Williams & Wilkins; 2007:1474\u20131488."},{"key":"4454_CR19","doi-asserted-by":"crossref","unstructured":"Fazio VW1, Kiran RP, Remzi FH, et al. Ileal pouch anal anastomosis: analysis of outcome and quality of life in 3707 patients. Ann Surg. 2013;257:679\u2013685.","DOI":"10.1097\/SLA.0b013e31827d99a2"},{"key":"4454_CR20","doi-asserted-by":"crossref","unstructured":"Chapman JR1, Larson DW, Wolff BG, et al. Ileal pouch-anal anastomosis: does age at the time of surgery affect outcome? Arch Surg. 2005;140:534\u2013539 (discussion 539-40).","DOI":"10.1001\/archsurg.140.6.534"},{"key":"4454_CR21","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1002\/ibd.20278","volume":"14","author":"M Ferrante","year":"2008","unstructured":"Ferrante M, Declerck S, De Hertogh G, et al. Outcome after proctocolectomy with ileal pouch-anal anastomosis for ulcerative colitis. Inflamm Bowel Dis. 2008;14:20\u201328.","journal-title":"Inflamm Bowel Dis"},{"key":"4454_CR22","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.cgh.2005.10.004","volume":"4","author":"B Shen","year":"2006","unstructured":"Shen B, Fazio VW, Remzi FH, et al. Risk factors for diseases of ileal pouch-anal anastomosis after restorative proctocolectomy for ulcerative colitis. Clinical Gastroenterology and Hepatology. 2006;4:81\u201389.","journal-title":"Clinical Gastroenterology and Hepatology"},{"key":"4454_CR23","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1007\/BF02054692","volume":"39","author":"D St\u00e5hlberg","year":"1996","unstructured":"St\u00e5hlberg D, Gullberg K, Liljeqvist L, Hellers G, L\u00f6fberg R. Pouchitis following pelvic pouch operation for ulcerative colitis. Incidence, cumulative risk, and risk factors. Dis Colon Rectum. 1996;39:1012\u20131018.","journal-title":"Dis Colon Rectum"},{"key":"4454_CR24","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1097\/00000658-199805000-00006","volume":"227","author":"CM Schmidt","year":"1998","unstructured":"Schmidt CM, Lazenby AJ, Hendrickson RJ, Sitzmann JV. Preoperative terminal ileal and colonic resection histopathology predicts risk of pouchitis in patients after ileoanal pull-through procedure. Ann Surg. 1998;227:654\u2013662. (discussion 663-5).","journal-title":"Ann Surg"},{"key":"4454_CR25","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1016\/S0016-5085(03)00171-9","volume":"124","author":"P Gionchetti","year":"2003","unstructured":"Gionchetti P, Rizzello F, Helwig U, et al. Prophylaxis of pouchitis onset with probiotic therapy: a double-blind, placebo-controlled trial. Gastroenterology. 2003;124:1202\u20131209.","journal-title":"Gastroenterology"},{"key":"4454_CR26","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1002\/ibd.20369","volume":"14","author":"A Pronio","year":"2008","unstructured":"Pronio A, Montesani C, Butteroni C, et al. Probiotic administration in patients with ileal pouch-anal anastomosis for ulcerative colitis is associated with expansion of mucosal regulatory cells. Inflamm Bowel Dis. 2008;14:662\u2013668.","journal-title":"Inflamm Bowel Dis"},{"key":"4454_CR27","doi-asserted-by":"crossref","first-page":"S465","DOI":"10.1053\/j.gastro.2004.02.027","volume":"126","author":"SJ Brown","year":"2004","unstructured":"Brown SJ, Megan J, Smith S, Matchet D, Elliott R. Bifidobacterium longum BB-536 and prevention of acute pouchitis. Gastroenterology. 2004;126:S465.","journal-title":"Gastroenterology"},{"key":"4454_CR28","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1080\/00365520152584815","volume":"36","author":"M Joelsson","year":"2001","unstructured":"Joelsson M, Andersson M, Bark T, et al. Allopurinol as prophylaxis against pouchitis following ileal pouch-anal anastomosis for ulcerative colitis. A randomized placebo-controlled double-blind study. Scand J Gastroenterol. 2001;36:1179\u20131184.","journal-title":"Scand J Gastroenterol"},{"key":"4454_CR29","first-page":"S69","volume":"138","author":"CY Ha","year":"2010","unstructured":"Ha CY, Bauer JJ, Lazarev M, et al. Early institution of tinidazole may prevent pouchitis following ileal-pouch anal anastomosis (IPAA) surgery in ulcerative colitis (UC) patients. Gastroenterology. 2010;138:S69.","journal-title":"Gastroenterology"},{"key":"4454_CR30","doi-asserted-by":"crossref","first-page":"2146","DOI":"10.1128\/AEM.56.7.2146-2151.1990","volume":"56","author":"F Rafii","year":"1990","unstructured":"Rafii F, Franklin W, Cerniglia CE. Azoreductase activity of anaerobic bacteria isolated from human intestinal microflora. Appl Environ Microbiol. 1990;56:2146\u20132151.","journal-title":"Appl Environ Microbiol"},{"key":"4454_CR31","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/S0022-3565(25)29238-2","volume":"181","author":"MA Peppercorn","year":"1972","unstructured":"Peppercorn MA, Goldman P. The role of intestinal bacteria in the metabolism of salicylazosulfapyridine. J Pharmacol Exp Ther. 1972;181:555\u2013562.","journal-title":"J Pharmacol Exp Ther"},{"key":"4454_CR32","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1136\/gut.34.1.101","volume":"34","author":"NA Shepherd","year":"1993","unstructured":"Shepherd NA, Healey CJ, Warren BF, Richman PI, Thomson WH, Wilkinson SP. Distribution of mucosal pathology and an assessment of colonic phenotypic change in the pelvic ileal reservoir. Gut. 1993;34:101\u2013105.","journal-title":"Gut"},{"key":"4454_CR33","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1136\/jcp.40.6.601","volume":"40","author":"NA Shepherd","year":"1987","unstructured":"Shepherd NA, Jass JR, Duval I, Moskowitz RL, Nicholls RJ, Morson BC. Restorative proctocolectomy with ileal reservoir: pathological and histochemical study of mucosal biopsy specimens. J Clin Pathol. 1987;40:601\u2013607.","journal-title":"J Clin Pathol"},{"key":"4454_CR34","doi-asserted-by":"crossref","first-page":"1803","DOI":"10.1002\/ibd.21022","volume":"15","author":"MW Johnson","year":"2009","unstructured":"Johnson MW, Rogers GB, Bruce KD, et al. Bacterial community diversity in cultures derived from healthy and inflamed ileal pouches after restorative proctocolectomy. Inflamm Bowel Dis. 2009;15:1803\u20131811.","journal-title":"Inflamm Bowel Dis"},{"key":"4454_CR35","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/j.cgh.2007.01.001","volume":"5","author":"S Komanduri","year":"2007","unstructured":"Komanduri S, Gillevet PM, Sikaroodi M, Mutlu E, Keshavarzian A. Dysbiosis in pouchitis: evidence of unique microfloral patterns in pouch inflammation. Clin Gastroenterol Hepatol. 2007;5:352\u2013360.","journal-title":"Clin Gastroenterol Hepatol"},{"key":"4454_CR36","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.surg.2011.02.009","volume":"150","author":"M Scarpa","year":"2011","unstructured":"Scarpa M, Grillo A, Faggian D, et al. Relationship between mucosa-associated microbiota and inflammatory parameters in the ileal pouch after restorative proctocolectomy for ulcerative colitis. Surgery. 2011;150:56\u201367.","journal-title":"Surgery"}],"container-title":["Digestive Diseases and Sciences"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-017-4454-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10620-017-4454-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-017-4454-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,14]],"date-time":"2025-06-14T18:13:14Z","timestamp":1749924794000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10620-017-4454-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1,21]]},"references-count":36,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,4]]}},"alternative-id":["4454"],"URL":"https:\/\/doi.org\/10.1007\/s10620-017-4454-9","relation":{},"ISSN":["0163-2116","1573-2568"],"issn-type":[{"type":"print","value":"0163-2116"},{"type":"electronic","value":"1573-2568"}],"subject":[],"published":{"date-parts":[[2017,1,21]]}}}