{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T22:22:03Z","timestamp":1759962123356,"version":"3.37.3"},"reference-count":50,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2017,5,18]],"date-time":"2017-05-18T00:00:00Z","timestamp":1495065600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100003625","name":"Ministry of Health and Welfare","doi-asserted-by":"publisher","award":["A120176","HI13C1345"],"award-info":[{"award-number":["A120176","HI13C1345"]}],"id":[{"id":"10.13039\/501100003625","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Ministry of Science","award":["NRF-2013R1A2A2A01067123","NRF-2014R1A1A1008096"],"award-info":[{"award-number":["NRF-2013R1A2A2A01067123","NRF-2014R1A1A1008096"]}]},{"DOI":"10.13039\/501100008005","name":"Yonsei University College of Medicine","doi-asserted-by":"publisher","award":["2012-31-0477"],"award-info":[{"award-number":["2012-31-0477"]}],"id":[{"id":"10.13039\/501100008005","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Dig Dis Sci"],"published-print":{"date-parts":[[2017,8]]},"DOI":"10.1007\/s10620-017-4606-y","type":"journal-article","created":{"date-parts":[[2017,5,18]],"date-time":"2017-05-18T01:47:44Z","timestamp":1495072064000},"page":"1953-1962","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Proteomic Analysis of Serum Amyloid A as a Potential Marker in Intestinal Beh\u00e7et\u2019s Disease"],"prefix":"10.1007","volume":"62","author":[{"given":"Hyun Jung","family":"Lee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jae Hyun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seung Won","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyun Ah","family":"Joo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hye Won","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"You Sun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soo Jung","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung Pil","family":"Hong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tae Il","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Won Ho","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young-Ho","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jae Hee","family":"Cheon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,5,18]]},"reference":[{"key":"4606_CR1","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1007\/s00535-007-2090-4","volume":"42","author":"K Kobayashi","year":"2007","unstructured":"Kobayashi K, Ueno F, Bito S, et al. Development of consensus statements for the diagnosis and management of intestinal Behcet\u2019s disease using a modified Delphi approach. J Gastroenterol. 2007;42:737\u2013745.","journal-title":"J Gastroenterol"},{"key":"4606_CR2","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1056\/NEJM199910213411707","volume":"341","author":"T Sakane","year":"1999","unstructured":"Sakane T, Takeno M, Suzuki N, Inaba G. Behcet\u2019s disease. The New England Journal of Medicine. 1999;341:1284\u20131291.","journal-title":"The New England Journal of Medicine."},{"key":"4606_CR3","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1053\/j.gastro.2005.02.053","volume":"128","author":"R Xavier","year":"2005","unstructured":"Xavier R, Podolsky DK. Commensal flora: wolf in sheep\u2019s clothing. Gastroenterology. 2005;128:1122\u20131126.","journal-title":"Gastroenterology"},{"key":"4606_CR4","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1097\/00004836-200003000-00006","volume":"30","author":"Y Bayraktar","year":"2000","unstructured":"Bayraktar Y, Ozaslan E, Van Thiel DH. Gastrointestinal manifestations of Behcet\u2019s disease. J Clin Gastroenterol. 2000;30:144\u2013154.","journal-title":"J Clin Gastroenterol"},{"key":"4606_CR5","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/s10620-008-0337-4","volume":"54","author":"EC Ebert","year":"2009","unstructured":"Ebert EC. Gastrointestinal manifestations of Behcet\u2019s disease. Dig Dis Sci. 2009;54:201\u2013207.","journal-title":"Dig Dis Sci"},{"key":"4606_CR6","doi-asserted-by":"crossref","first-page":"155","DOI":"10.5217\/ir.2013.11.3.155","volume":"11","author":"HW Lee","year":"2013","unstructured":"Lee HW, Kim WH, Cheon JH. The medical treatments of intestinal Beh\u00e7et\u2019s disease: an update. Intestinal Research. 2013;11:155\u2013160.","journal-title":"Intestinal Research."},{"key":"4606_CR7","doi-asserted-by":"crossref","first-page":"e38","DOI":"10.1097\/MCG.0b013e3182431d56","volume":"46","author":"YS Jung","year":"2012","unstructured":"Jung YS, Hong SP, Kim TI, Kim WH, Cheon JH. Long-term clinical outcomes and factors predictive of relapse after 5-aminosalicylate or sulfasalazine therapy in patients with intestinal Behcet disease. J Clin Gastroenterol. 2012;46:e38\u2013e45.","journal-title":"J Clin Gastroenterol"},{"key":"4606_CR8","doi-asserted-by":"crossref","first-page":"2130","DOI":"10.1002\/ibd.21600","volume":"17","author":"YS Jung","year":"2011","unstructured":"Jung YS, Kim SW, Yoon JY, et al. Expression of a soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) correlates with clinical disease activity in intestinal Behcet\u2019s disease. Inflamm Bowel Dis. 2011;17:2130\u20132137.","journal-title":"Inflamm Bowel Dis"},{"key":"4606_CR9","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1002\/ibd.21212","volume":"16","author":"G Roda","year":"2010","unstructured":"Roda G, Caponi A, Benevento M, et al. New proteomic approaches for biomarker discovery in inflammatory bowel disease. Inflamm Bowel Dis. 2010;16:1239\u20131246.","journal-title":"Inflamm Bowel Dis"},{"key":"4606_CR10","doi-asserted-by":"crossref","first-page":"2755","DOI":"10.1007\/s10620-012-2291-4","volume":"57","author":"A Vaiopoulou","year":"2012","unstructured":"Vaiopoulou A, Gazouli M, Theodoropoulos G, Zografos G. Current advantages in the application of proteomics in inflammatory bowel disease. Dig Dis Sci. 2012;57:2755\u20132764.","journal-title":"Dig Dis Sci"},{"key":"4606_CR11","doi-asserted-by":"crossref","first-page":"27","DOI":"10.4291\/wjgp.v7.i1.27","volume":"7","author":"PP Chan","year":"2016","unstructured":"Chan PP, Wasinger VC, Leong RW. Current application of proteomics in biomarker discovery for inflammatory bowel disease. World Journal of Gastrointestinal Pathophysiology. 2016;7:27\u201337.","journal-title":"World Journal of Gastrointestinal Pathophysiology."},{"key":"4606_CR12","doi-asserted-by":"crossref","first-page":"2492","DOI":"10.1038\/ajg.2009.331","volume":"104","author":"JH Cheon","year":"2009","unstructured":"Cheon JH, Kim ES, Shin SJ, et al. Development and validation of novel diagnostic criteria for intestinal Behcet\u2019s disease in Korean patients with ileocolonic ulcers. Am J Gastroenterol. 2009;104:2492\u20132499.","journal-title":"Am J Gastroenterol"},{"key":"4606_CR13","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1002\/ibd.21313","volume":"17","author":"JH Cheon","year":"2011","unstructured":"Cheon JH, Han DS, Park JY, et al. Development, validation, and responsiveness of a novel disease activity index for intestinal Behcet\u2019s disease. Inflamm Bowel Dis. 2011;17:605\u2013613.","journal-title":"Inflamm Bowel Dis"},{"key":"4606_CR14","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1053\/jhep.2002.33204","volume":"35","author":"KS Park","year":"2002","unstructured":"Park KS, Kim H, Kim NG, et al. Proteomic analysis and molecular characterization of tissue ferritin light chain in hepatocellular carcinoma. Hepatology. 2002;35:1459\u20131466.","journal-title":"Hepatology"},{"key":"4606_CR15","doi-asserted-by":"crossref","first-page":"1955","DOI":"10.1002\/pmic.200300558","volume":"3","author":"BK Choi","year":"2003","unstructured":"Choi BK, Cho YM, Bae SH, Zoubaulis CC, Paik YK. Single-step perfusion chromatography with a throughput potential for enhanced peptide detection by matrix-assisted laser desorption\/ionization-mass spectrometry. Proteomics. 2003;3:1955\u20131961.","journal-title":"Proteomics"},{"key":"4606_CR16","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1136\/gut.2011.238477","volume":"60","author":"SW Kim","year":"2011","unstructured":"Kim SW, Kim ES, Moon CM, et al. Genetic polymorphisms of IL-23R and IL-17A and novel insights into their associations with inflammatory bowel disease. Gut. 2011;60:1527\u20131536.","journal-title":"Gut"},{"key":"4606_CR17","doi-asserted-by":"crossref","first-page":"1717","DOI":"10.1002\/ibd.21263","volume":"16","author":"CL Noble","year":"2010","unstructured":"Noble CL, Abbas AR, Lees CW, et al. Characterization of intestinal gene expression profiles in Crohn\u2019s disease by genome-wide microarray analysis. Inflamm Bowel Dis. 2010;16:1717\u20131728.","journal-title":"Inflamm Bowel Dis"},{"key":"4606_CR18","doi-asserted-by":"crossref","first-page":"1398","DOI":"10.1136\/gut.2008.148395","volume":"57","author":"CL Noble","year":"2008","unstructured":"Noble CL, Abbas AR, Cornelius J, et al. Regional variation in gene expression in the healthy colon is dysregulated in ulcerative colitis. Gut. 2008;57:1398\u20131405.","journal-title":"Gut"},{"key":"4606_CR19","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.autrev.2006.03.006","volume":"6","author":"S Sodin-Semrl","year":"2006","unstructured":"Sodin-Semrl S, Zigon P, Cucnik S, et al. Serum amyloid A in autoimmune thrombosis. Autoimmun Rev. 2006;6:21\u201327.","journal-title":"Autoimmun Rev"},{"key":"4606_CR20","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1111\/j.1365-2362.1987.tb01143.x","volume":"17","author":"RE Chambers","year":"1987","unstructured":"Chambers RE, Stross P, Barry RE, Whicher JT. Serum amyloid A protein compared with C-reactive protein, alpha 1-antichymotrypsin and alpha 1-acid glycoprotein as a monitor of inflammatory bowel disease. Eur J Clin Invest. 1987;17:460\u2013467.","journal-title":"Eur J Clin Invest"},{"key":"4606_CR21","doi-asserted-by":"crossref","first-page":"1275-e1272","DOI":"10.1053\/j.gastro.2015.07.003","volume":"149","author":"BE Sands","year":"2015","unstructured":"Sands BE. Biomarkers of inflammation in inflammatory bowel disease. Gastroenterology. 2015;149:1275-e1272\u20131285.e1272.","journal-title":"Gastroenterology"},{"key":"4606_CR22","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1136\/gut.2005.069476","volume":"55","author":"S Vermeire","year":"2006","unstructured":"Vermeire S, Van Assche G, Rutgeerts P. Laboratory markers in IBD: useful, magic, or unnecessary toys? Gut. 2006;55:426\u2013431.","journal-title":"Gut"},{"key":"4606_CR23","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1038\/35015709","volume":"405","author":"A Pandey","year":"2000","unstructured":"Pandey A, Mann M. Proteomics to study genes and genomes. Nature. 2000;405:837\u2013846.","journal-title":"Nature"},{"key":"4606_CR24","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.1007\/s10350-006-0706-z","volume":"49","author":"CH Choi","year":"2006","unstructured":"Choi CH, Kim TI, Kim BC, et al. Anti-Saccharomyces cerevisiae antibody in intestinal Behcet\u2019s disease patients: relation to clinical course. Dis Colon Rectum. 2006;49:1849\u20131859.","journal-title":"Dis Colon Rectum"},{"key":"4606_CR25","doi-asserted-by":"crossref","first-page":"22","DOI":"10.3349\/ymj.2016.57.1.22","volume":"57","author":"DH Kim","year":"2016","unstructured":"Kim DH, Cheon JH. Intestinal Behcet\u2019s disease: a true inflammatory bowel disease or merely an intestinal complication of systemic vasculitis? Yonsei Med J. 2016;57:22\u201332.","journal-title":"Yonsei Med J"},{"key":"4606_CR26","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1080\/14789450.2016.1182431","volume":"13","author":"JF Timms","year":"2016","unstructured":"Timms JF, Hale OJ, Cramer R. Advances in mass spectrometry-based cancer research and analysis: from cancer proteomics to clinical diagnostics. Expert Review of Proteomics. 2016;13:593\u2013607.","journal-title":"Expert Review of Proteomics."},{"key":"4606_CR27","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1586\/14789450.5.1.1","volume":"5","author":"IL Goldknopf","year":"2008","unstructured":"Goldknopf IL. Blood-based proteomics for personalized medicine: examples from neurodegenerative disease. Expert Review of Proteomics. 2008;5:1\u20138.","journal-title":"Expert Review of Proteomics."},{"key":"4606_CR28","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1074\/mcp.R200007-MCP200","volume":"1","author":"NL Anderson","year":"2002","unstructured":"Anderson NL, Anderson NG. The human plasma proteome: history, character, and diagnostic prospects. Molecular & Cellular Proteomics: MCP. 2002;1:845\u2013867.","journal-title":"Molecular & Cellular Proteomics: MCP."},{"key":"4606_CR29","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1021\/pr0500657","volume":"4","author":"JM Jacobs","year":"2005","unstructured":"Jacobs JM, Adkins JN, Qian WJ, et al. Utilizing human blood plasma for proteomic biomarker discovery. J Proteome Res. 2005;4:1073\u20131085.","journal-title":"J Proteome Res"},{"key":"4606_CR30","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1016\/j.thromres.2008.04.004","volume":"123","author":"J Shen","year":"2009","unstructured":"Shen J, Ran ZH, Zhang Y, et al. Biomarkers of altered coagulation and fibrinolysis as measures of disease activity in active inflammatory bowel disease: a gender-stratified, cohort analysis. Thromb Res. 2009;123:604\u2013611.","journal-title":"Thromb Res"},{"key":"4606_CR31","doi-asserted-by":"crossref","first-page":"3127","DOI":"10.1016\/j.jchromb.2009.08.003","volume":"877","author":"P Nanni","year":"2009","unstructured":"Nanni P, Levander F, Roda G, Caponi A, James P, Roda A. A label-free nano-liquid chromatography-mass spectrometry approach for quantitative serum peptidomics in Crohn\u2019s disease patients. J Chromatogr, B: Anal Technol Biomed Life Sci. 2009;877:3127\u20133136.","journal-title":"J Chromatogr, B: Anal Technol Biomed Life Sci"},{"key":"4606_CR32","doi-asserted-by":"crossref","first-page":"E2332","DOI":"10.1073\/pnas.1222669110","volume":"110","author":"CG Knutson","year":"2013","unstructured":"Knutson CG, Mangerich A, Zeng Y, et al. Chemical and cytokine features of innate immunity characterize serum and tissue profiles in inflammatory bowel disease. Proc Natl Acad Sci USA. 2013;110:E2332\u2013E2341.","journal-title":"Proc Natl Acad Sci USA"},{"key":"4606_CR33","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1080\/00365529850171927","volume":"33","author":"J Kjeldsen","year":"1998","unstructured":"Kjeldsen J, Lassen JF, Brandslund I, Schaffalitzky de Muckadell OB. Markers of coagulation and fibrinolysis as measures of disease activity in inflammatory bowel disease. Scand J Gastroenterol. 1998;33:637\u2013643.","journal-title":"Scand J Gastroenterol"},{"key":"4606_CR34","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1002\/ibd.20078","volume":"13","author":"UC Broedl","year":"2007","unstructured":"Broedl UC, Schachinger V, Lingenhel A, et al. Apolipoprotein A-IV is an independent predictor of disease activity in patients with inflammatory bowel disease. Inflamm Bowel Dis. 2007;13:391\u2013397.","journal-title":"Inflamm Bowel Dis"},{"key":"4606_CR35","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1172\/JCI200421233","volume":"114","author":"T Vowinkel","year":"2004","unstructured":"Vowinkel T, Mori M, Krieglstein CF, et al. Apolipoprotein A-IV inhibits experimental colitis. J Clin Investig. 2004;114:260\u2013269.","journal-title":"J Clin Investig"},{"key":"4606_CR36","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1002\/ibd.20110","volume":"13","author":"F Wu","year":"2007","unstructured":"Wu F, Dassopoulos T, Cope L, et al. Genome-wide gene expression differences in Crohn\u2019s disease and ulcerative colitis from endoscopic pinch biopsies: insights into distinctive pathogenesis. Inflamm Bowel Dis. 2007;13:807\u2013821.","journal-title":"Inflamm Bowel Dis"},{"key":"4606_CR37","doi-asserted-by":"crossref","first-page":"4500","DOI":"10.1021\/pr800279m","volume":"7","author":"L Mao","year":"2008","unstructured":"Mao L, Dong H, Yang P, et al. MALDI-TOF\/TOF-MS reveals elevated serum haptoglobin and amyloid A in Behcet\u2019s disease. J Proteome Res. 2008;7:4500\u20134507.","journal-title":"J Proteome Res"},{"key":"4606_CR38","first-page":"1","volume":"149","author":"D Kamimura","year":"2003","unstructured":"Kamimura D, Ishihara K, Hirano T. IL-6 signal transduction and its physiological roles: the signal orchestration model. Rev Physiol Biochem Pharmacol. 2003;149:1\u201338.","journal-title":"Rev Physiol Biochem Pharmacol"},{"key":"4606_CR39","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.cytogfr.2012.04.001","volume":"23","author":"C Garbers","year":"2012","unstructured":"Garbers C, Hermanns HM, Schaper F, et al. Plasticity and cross-talk of interleukin 6-type cytokines. Cytokine Growth Factor Rev. 2012;23:85\u201397.","journal-title":"Cytokine Growth Factor Rev"},{"key":"4606_CR40","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1046\/j.1432-1327.1999.00657.x","volume":"265","author":"CM Uhlar","year":"1999","unstructured":"Uhlar CM, Whitehead AS. Serum amyloid A, the major vertebrate acute-phase reactant. European Journal of Biochemistry\/FEBS. 1999;265:501\u2013523.","journal-title":"European Journal of Biochemistry\/FEBS."},{"key":"4606_CR41","first-page":"1295","volume":"20","author":"N Upragarin","year":"2005","unstructured":"Upragarin N, Landman WJ, Gaastra W, Gruys E. Extrahepatic production of acute phase serum amyloid A. Histol Histopathol. 2005;20:1295\u20131307.","journal-title":"Histol Histopathol"},{"key":"4606_CR42","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1136\/ard.2010.142240","volume":"70","author":"M Connolly","year":"2011","unstructured":"Connolly M, Veale DJ, Fearon U. Acute serum amyloid A regulates cytoskeletal rearrangement, cell matrix interactions and promotes cell migration in rheumatoid arthritis. Ann Rheum Dis. 2011;70:1296\u20131303.","journal-title":"Ann Rheum Dis"},{"key":"4606_CR43","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1161\/01.CIR.0000115516.54550.B1","volume":"109","author":"BD Johnson","year":"2004","unstructured":"Johnson BD, Kip KE, Marroquin OC, et al. Serum amyloid A as a predictor of coronary artery disease and cardiovascular outcome in women: the National Heart, Lung, and Blood Institute-Sponsored Women\u2019s Ischemia Syndrome Evaluation (WISE). Circulation. 2004;109:726\u2013732.","journal-title":"Circulation"},{"key":"4606_CR44","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1002\/eji.200425688","volume":"35","author":"HB Jijon","year":"2005","unstructured":"Jijon HB, Madsen KL, Walker JW, Allard B, Jobin C. Serum amyloid A activates NF-kappaB and proinflammatory gene expression in human and murine intestinal epithelial cells. Eur J Immunol. 2005;35:718\u2013726.","journal-title":"Eur J Immunol"},{"key":"4606_CR45","doi-asserted-by":"crossref","first-page":"22","DOI":"10.4049\/jimmunol.181.1.22","volume":"181","author":"N Cheng","year":"2008","unstructured":"Cheng N, He R, Tian J, Ye PP, Ye RD. Cutting edge: TLR2 is a functional receptor for acute-phase serum amyloid A. J Immunol. 2008;181:22\u201326.","journal-title":"J Immunol."},{"key":"4606_CR46","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1189\/jlb.0407203","volume":"83","author":"S Sandri","year":"2008","unstructured":"Sandri S, Rodriguez D, Gomes E, Monteiro HP, Russo M, Campa A. Is serum amyloid A an endogenous TLR4 agonist? J Leukoc Biol. 2008;83:1174\u20131180.","journal-title":"J Leukoc Biol"},{"key":"4606_CR47","doi-asserted-by":"crossref","first-page":"6119","DOI":"10.4049\/jimmunol.1002843","volume":"186","author":"K Niemi","year":"2011","unstructured":"Niemi K, Teirila L, Lappalainen J, et al. Serum amyloid A activates the NLRP3 inflammasome via P2X7 receptor and a cathepsin B-sensitive pathway. J Immunol. 2011;186:6119\u20136128.","journal-title":"J Immunol."},{"key":"4606_CR48","doi-asserted-by":"crossref","first-page":"64","DOI":"10.4049\/jimmunol.1100500","volume":"187","author":"JL Ather","year":"2011","unstructured":"Ather JL, Ckless K, Martin R, et al. Serum amyloid A activates the NLRP3 inflammasome and promotes Th17 allergic asthma in mice. J Immunol. 2011;187:64\u201373.","journal-title":"J Immunol."},{"key":"4606_CR49","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1186\/s13075-016-1009-y","volume":"18","author":"YG Hwang","year":"2016","unstructured":"Hwang YG, Balasubramani GK, Metes ID, Levesque MC, Bridges SL Jr, Moreland LW. Differential response of serum amyloid A to different therapies in early rheumatoid arthritis and its potential value as a disease activity biomarker. Arthritis Research & Therapy. 2016;18:108.","journal-title":"Arthritis Research & Therapy."},{"key":"4606_CR50","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.3899\/jrheum.080755","volume":"36","author":"S Visvanathan","year":"2009","unstructured":"Visvanathan S, Wagner C, Rojas J, et al. E-selectin, interleukin 18, serum amyloid a, and matrix metalloproteinase 9 are associated with clinical response to golimumab plus methotrexate in patients with active rheumatoid arthritis despite methotrexate therapy. J Rheumatol. 2009;36:1371\u20131379.","journal-title":"J Rheumatol"}],"container-title":["Digestive Diseases and Sciences"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10620-017-4606-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-017-4606-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-017-4606-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,7,15]],"date-time":"2017-07-15T04:31:02Z","timestamp":1500093062000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10620-017-4606-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5,18]]},"references-count":50,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2017,8]]}},"alternative-id":["4606"],"URL":"https:\/\/doi.org\/10.1007\/s10620-017-4606-y","relation":{},"ISSN":["0163-2116","1573-2568"],"issn-type":[{"type":"print","value":"0163-2116"},{"type":"electronic","value":"1573-2568"}],"subject":[],"published":{"date-parts":[[2017,5,18]]}}}