{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T15:56:45Z","timestamp":1760889405954},"reference-count":16,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2017,5,27]],"date-time":"2017-05-27T00:00:00Z","timestamp":1495843200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Dig Dis Sci"],"published-print":{"date-parts":[[2017,8]]},"DOI":"10.1007\/s10620-017-4616-9","type":"journal-article","created":{"date-parts":[[2017,5,27]],"date-time":"2017-05-27T04:04:29Z","timestamp":1495857869000},"page":"2196-2200","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Nutritional Therapy in Very Early-Onset Inflammatory Bowel Disease: A Case Report"],"prefix":"10.1007","volume":"62","author":[{"given":"Talya L.","family":"Miller","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dale","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mathew","family":"Giefer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ghassan","family":"Wahbeh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David L.","family":"Suskind","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,5,27]]},"reference":[{"key":"4616_CR1","doi-asserted-by":"crossref","first-page":"1795","DOI":"10.1136\/gutjnl-2012-303956","volume":"62","author":"HH Uhlig","year":"2013","unstructured":"Uhlig HH. Monogenic diseases associated with intestinal inflammation: implications for the understanding of inflammatory bowel disease. Gut. 2013;62:1795\u20131805.","journal-title":"Gut"},{"key":"4616_CR2","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1002\/ibd.20171","volume":"13","author":"L Ridder de","year":"2007","unstructured":"de Ridder L, Weersma RK, Dijkstra G, et al. Genetic susceptibility has a more important role in pediatric-onset Crohn\u2019s disease than in adult-onset Crohn\u2019s disease. Inflamm Bowel Dis. 2007;13:1083\u20131092.","journal-title":"Inflamm Bowel Dis"},{"key":"4616_CR3","doi-asserted-by":"crossref","unstructured":"Benchimol EI, Mack DR, Nguyen GC, et al. Incidence, outcomes, and health services burden of very early onset inflammatory bowel disease. Gastroenterology. 2014;147:803\u2013813 e807; quiz e814\u2013805.","DOI":"10.1053\/j.gastro.2014.06.023"},{"key":"4616_CR4","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1016\/S0140-6736(10)61008-2","volume":"376","author":"EO Glocker","year":"2010","unstructured":"Glocker EO, Frede N, Perro M, et al. Infant colitis\u2014it\u2019s in the genes. Lancet. 2010;376:1272.","journal-title":"Lancet"},{"key":"4616_CR5","doi-asserted-by":"crossref","first-page":"2033","DOI":"10.1056\/NEJMoa0907206","volume":"361","author":"EO Glocker","year":"2009","unstructured":"Glocker EO, Kotlarz D, Boztug K, et al. Inflammatory bowel disease and mutations affecting the interleukin-10 receptor. N Engl J Med. 2009;361:2033\u20132045.","journal-title":"N Engl J Med"},{"key":"4616_CR6","doi-asserted-by":"crossref","first-page":"2146","DOI":"10.1172\/JCI5084","volume":"102","author":"CB Foster","year":"1998","unstructured":"Foster CB, Lehrnbecher T, Mol F, et al. Host defense molecule polymorphisms influence the risk for immune-mediated complications in chronic granulomatous disease. J Clin Invest. 1998;102:2146\u20132155.","journal-title":"J Clin Invest"},{"key":"4616_CR7","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1136\/gutjnl-2011-300078","volume":"61","author":"AM Muise","year":"2012","unstructured":"Muise AM, Xu W, Guo CH, et al. NADPH oxidase complex and IBD candidate gene studies: identification of a rare variant in NCF2 that results in reduced binding to RAC2. Gut. 2012;61:1028\u20131035.","journal-title":"Gut"},{"key":"4616_CR8","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1038\/353668a0","volume":"353","author":"A Abo","year":"1991","unstructured":"Abo A, Pick E, Hall A, Totty N, Teahan CG, Segal AW. Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1. Nature. 1991;353:668\u2013670.","journal-title":"Nature"},{"key":"4616_CR9","doi-asserted-by":"crossref","first-page":"3309","DOI":"10.1182\/blood-2009-07-231498","volume":"114","author":"JD Matute","year":"2009","unstructured":"Matute JD, Arias AA, Wright NA, et al. A new genetic subgroup of chronic granulomatous disease with autosomal recessive mutations in p40 phox and selective defects in neutrophil NADPH oxidase activity. Blood. 2009;114:3309\u20133315.","journal-title":"Blood"},{"key":"4616_CR10","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1097\/00005176-200007000-00005","volume":"31","author":"RB Heuschkel","year":"2000","unstructured":"Heuschkel RB, Menache CC, Megerian JT, Baird AE. Enteral nutrition and corticosteroids in the treatment of acute Crohn\u2019s disease in children. J Pediatr Gastroenterol Nutr. 2000;31:8\u201315.","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"4616_CR11","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1097\/MPG.0b013e318235b397","volume":"54","author":"J Critch","year":"2012","unstructured":"Critch J, Day AS, Otley A, et al. Use of enteral nutrition for the control of intestinal inflammation in pediatric Crohn disease. J Pediatr Gastroenterol Nutr. 2012;54:298\u2013305.","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"4616_CR12","first-page":"CD000542","volume":"1","author":"M Zachos","year":"2007","unstructured":"Zachos M, Tondeur M, Griffiths AM. Enteral nutritional therapy for induction of remission in Crohn\u2019s disease. Cochrane Database Syst Rev. 2007;1:CD000542.","journal-title":"Cochrane Database Syst Rev"},{"key":"4616_CR13","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1016\/j.cgh.2006.03.010","volume":"4","author":"O Borrelli","year":"2006","unstructured":"Borrelli O, Cordischi L, Cirulli M, et al. Polymeric diet alone versus corticosteroids in the treatment of active pediatric Crohn\u2019s disease: a randomized controlled open-label trial. Clin Gastroenterol Hepatol. 2006;4:744\u2013753.","journal-title":"Clin Gastroenterol Hepatol"},{"key":"4616_CR14","doi-asserted-by":"crossref","unstructured":"Oliva-Hemker M, Hutfless S, Al Kazzi ES, et al. Clinical Presentation and five-year therapeutic management of very early-onset inflammatory bowel disease in a large North American cohort. J Pediatr. 2015;167:527\u2013532 e521\u2013523.","DOI":"10.1016\/j.jpeds.2015.04.045"},{"key":"4616_CR15","doi-asserted-by":"crossref","first-page":"1398","DOI":"10.1111\/apt.12770","volume":"39","author":"K Frivolt","year":"2014","unstructured":"Frivolt K, Schwerd T, Werkstetter KJ, et al. Repeated exclusive enteral nutrition in the treatment of paediatric Crohn\u2019s disease: predictors of efficacy and outcome. Aliment Pharmacol Ther. 2014;39:1398\u20131407.","journal-title":"Aliment Pharmacol Ther"},{"key":"4616_CR16","doi-asserted-by":"crossref","first-page":"1672","DOI":"10.1002\/ibd.21916","volume":"18","author":"K Gerasimidis","year":"2012","unstructured":"Gerasimidis K, Talwar D, Duncan A, et al. Impact of exclusive enteral nutrition on body composition and circulating micronutrients in plasma and erythrocytes of children with active Crohn\u2019s disease. Inflamm Bowel Dis. 2012;18:1672\u20131681.","journal-title":"Inflamm Bowel Dis"}],"container-title":["Digestive Diseases and Sciences"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10620-017-4616-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-017-4616-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-017-4616-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,25]],"date-time":"2019-09-25T05:22:41Z","timestamp":1569388961000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10620-017-4616-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5,27]]},"references-count":16,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2017,8]]}},"alternative-id":["4616"],"URL":"https:\/\/doi.org\/10.1007\/s10620-017-4616-9","relation":{},"ISSN":["0163-2116","1573-2568"],"issn-type":[{"value":"0163-2116","type":"print"},{"value":"1573-2568","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,5,27]]}}}