{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T19:06:28Z","timestamp":1648753588167},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2017,11,15]],"date-time":"2017-11-15T00:00:00Z","timestamp":1510704000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Dig Dis Sci"],"published-print":{"date-parts":[[2018,1]]},"DOI":"10.1007\/s10620-017-4840-3","type":"journal-article","created":{"date-parts":[[2017,11,15]],"date-time":"2017-11-15T05:12:50Z","timestamp":1510722770000},"page":"72-80","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Effect of Low-Dose Aspirin on Chronic Acid Reflux Esophagitis in Rats"],"prefix":"10.1007","volume":"63","author":[{"given":"Takahiro","family":"Masuda","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fumiaki","family":"Yano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuo","family":"Omura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuto","family":"Tsuboi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masato","family":"Hoshino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Se Ryung","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shunsuke","family":"Akimoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideyuki","family":"Kashiwagi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsuhiko","family":"Yanaga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,11,15]]},"reference":[{"key":"4840_CR1","doi-asserted-by":"crossref","first-page":"1900","DOI":"10.1111\/j.1572-0241.2006.00630.x","volume":"101","author":"N Vakil","year":"2006","unstructured":"Vakil N, van Zanten SV, Kahrilas P, Dent J, Jones R. The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus. Am J Gastroenterol. 2006;101:1900\u20131920.","journal-title":"Am J Gastroenterol"},{"key":"4840_CR2","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1007\/s00535-009-0047-5","volume":"44","author":"Y Fujiwara","year":"2009","unstructured":"Fujiwara Y, Arakawa T. Epidemiology and clinical characteristics of GERD in Japanese population. J Gastroenterol. 2009;44:518\u2013534.","journal-title":"J Gastroenterol"},{"key":"4840_CR3","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.1016\/S0140-6736(09)60503-1","volume":"373","author":"C Baigent","year":"2009","unstructured":"Baigent C, Blackwell L, Collins R, et al. Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials. Lancet. 2009;373:1849\u20131860.","journal-title":"Lancet"},{"key":"4840_CR4","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1016\/S0140-6736(07)60282-7","volume":"369","author":"WK Leung","year":"2007","unstructured":"Leung WK, Bjarnason I, Wong VW, Sung JJ, Chan FK. Small bowel enteropathy associated with chronic low-dose aspirin therapy. Lancet. 2007;369:614.","journal-title":"Lancet"},{"key":"4840_CR5","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1007\/s00535-009-0040-z","volume":"44","author":"H Endo","year":"2009","unstructured":"Endo H, Hosono K, Inamori M, et al. Characteristics of small bowel injury in symptomatic chronic low-dose aspirin users: the experience of two medical centers in capsule endoscopy. J Gastroenterol. 2009;44:544\u2013549.","journal-title":"J Gastroenterol"},{"key":"4840_CR6","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/252963","author":"Y Shimada","year":"2015","unstructured":"Shimada Y, Nagahara A, Hojo M, et al. Upper gastrointestinal mucosal injury and symptoms in elderly low-dose aspirin users. Gastroenterol Res Pract. 2015. \n                        https:\/\/doi.org\/10.1155\/2015\/252963\n                        \n                    .","journal-title":"Gastroenterol Res Pract"},{"key":"4840_CR7","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1097\/00042737-200212000-00005","volume":"14","author":"AS Taha","year":"2002","unstructured":"Taha AS, Angerson WJ, Morran CG. Correlation between erosive oesophagitis and gastro-duodenal disease: the influence of aspirin, simple analgesics, and Helicobacter pylori. Eur J Gastroenterol Hepatol. 2002;14:1313\u20131317.","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"4840_CR8","doi-asserted-by":"crossref","first-page":"2465","DOI":"10.1111\/j.1572-0241.2008.01995.x","volume":"103","author":"N Yeomans","year":"2008","unstructured":"Yeomans N, Lanas A, Labenz J, et al. Efficacy of esomeprazole (20\u00a0mg once daily) for reducing the risk of gastroduodenal ulcers associated with continuous use of low-dose aspirin. Am J Gastroenterol. 2008;103:2465\u20132473.","journal-title":"Am J Gastroenterol"},{"key":"4840_CR9","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1111\/j.1440-1746.2009.06105.x","volume":"25","author":"T Yamamoto","year":"2010","unstructured":"Yamamoto T, Mishina Y, Ebato T, et al. Prevalence of erosive esophagitis among Japanese patients taking low-dose aspirin. J Gastroenterol Hepatol. 2010;25:792\u2013794.","journal-title":"J Gastroenterol Hepatol"},{"key":"4840_CR10","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1080\/003655299750025020","volume":"34","author":"N Omura","year":"1999","unstructured":"Omura N, Kashiwagi H, Chen G, Suzuki Y, Yano F, Aoki T. Establishment of surgically induced chronic acid reflux esophagitis in rats. Scand J Gastroenterol. 1999;34:948\u2013953.","journal-title":"Scand J Gastroenterol"},{"key":"4840_CR11","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1007\/s00535-009-0180-1","volume":"45","author":"H Miwa","year":"2010","unstructured":"Miwa H, Koseki J, Oshima T, et al. Rikkunshito, a traditional Japanese medicine, may relieve abdominal symptoms in rats with experimental esophagitis by improving the barrier function of epithelial cells in esophageal mucosa. J Gastroenterol. 2010;45:478\u2013487.","journal-title":"J Gastroenterol"},{"key":"4840_CR12","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/504816","author":"M Nahata","year":"2013","unstructured":"Nahata M, Saegusa Y, Harada Y, Tsuchiya N, Hattori T, Takeda H. Changes in ghrelin-related factors in gastroesophageal reflux disease in rats. Gastroenterol Res Pract. 2013. \n                        https:\/\/doi.org\/10.1155\/2013\/504816\n                        \n                    .","journal-title":"Gastroenterol Res Pract"},{"key":"4840_CR13","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1136\/gutjnl-2011-301389","volume":"62","author":"T Masaka","year":"2013","unstructured":"Masaka T, Iijima K, Endo H, et al. Gender differences in oesophageal mucosal injury in a reflux oesophagitis model of rats. Gut. 2013;62:6\u201314.","journal-title":"Gut"},{"key":"4840_CR14","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.2119\/molmed.2015.00098","volume":"21","author":"H Abdel-Aziz","year":"2015","unstructured":"Abdel-Aziz H, Schneider M, Neuhuber W, et al. GPR84 and TREM-1 signaling contribute to the pathogenesis of reflux esophagitis. Mol Med. 2015;21:1011\u20131024.","journal-title":"Mol Med"},{"key":"4840_CR15","doi-asserted-by":"crossref","first-page":"1392","DOI":"10.1016\/j.cgh.2007.08.011","volume":"5","author":"J Lee","year":"2007","unstructured":"Lee J, Anggiansah A, Anggiansah R, Young A, Wong T, Fox M. Effects of age on the gastroesophageal junction, esophageal motility, and reflux disease. Clin Gastroenterol Hepatol. 2007;5:1392\u20131398.","journal-title":"Clin Gastroenterol Hepatol"},{"key":"4840_CR16","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.cgh.2006.12.013","volume":"5","author":"M Fox","year":"2007","unstructured":"Fox M, Barr C, Nolan S, Lomer M, Anggiansah A, Wong T. The effects of dietary fat and calorie density on esophageal acid exposure and reflux symptoms. Clin Gastroenterol Hepatol. 2007;5:439\u2013444.","journal-title":"Clin Gastroenterol Hepatol"},{"key":"4840_CR17","doi-asserted-by":"crossref","first-page":"199","DOI":"10.7326\/0003-4819-143-3-200508020-00006","volume":"143","author":"H Hampel","year":"2005","unstructured":"Hampel H, Abraham NS, El-Serag HB. Meta-analysis: obesity and the risk for gastroesophageal reflux disease and its complications. Ann Intern Med. 2005;143:199\u2013211.","journal-title":"Ann Intern Med"},{"key":"4840_CR18","first-page":"1195","volume":"25","author":"T Xie","year":"2013","unstructured":"Xie T, Cui X, Zheng H, Chen D, He L, Jiang B. Meta-analysis: eradication of Helicobacter pylori infection is associated with the development of endoscopic gastroesophageal reflux disease. Eur J Gastroenterol Hepatol. 2013;25:1195\u20131205.","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"4840_CR19","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S0140-6736(09)61246-0","volume":"374","author":"AS Taha","year":"2009","unstructured":"Taha AS, McCloskey C, Prasad R, Bezlyak V. Famotidine for the prevention of peptic ulcers and oesophagitis in patients taking low-dose aspirin (FAMOUS): a phase III, randomised, double-blind, placebo-controlled trial. Lancet. 2009;374:119\u2013125.","journal-title":"Lancet"},{"key":"4840_CR20","first-page":"e387","volume":"3","author":"T Masuda","year":"2017","unstructured":"Masuda T, Mittal SK. Current animal models of gastroesophageal reflux disease, Barrett\u2019s esophagus, and esophageal adenocarcinoma. J Nat Sci. 2017;3:e387.","journal-title":"J Nat Sci"},{"key":"4840_CR21","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1097\/00042737-199511000-00009","volume":"7","author":"AI Lanas","year":"1995","unstructured":"Lanas AI, Sousa FL, Ortego J, et al. Aspirin renders the oesophageal mucosa more permeable to acid and pepsin. Eur J Gastroenterol Hepatol. 1995;7:1065\u20131072.","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"4840_CR22","first-page":"75","volume":"62","author":"M Pawlik","year":"2011","unstructured":"Pawlik M, Pajdo R, Kwiecien S, et al. Nitric oxide (NO)-releasing aspirin exhibits a potent esophagoprotection in experimental model of acute reflux esophagitis. Role of nitric oxide and proinflammatory cytokines. J Physiol Pharmacol. 2011;62:75\u201386.","journal-title":"J Physiol Pharmacol"},{"key":"4840_CR23","first-page":"5","volume":"56","author":"SJ Konturek","year":"2005","unstructured":"Konturek SJ, Konturek PC, Brzozowski T. Prostaglandins and ulcer healing. J Physiol Pharmacol. 2005;56:5\u201331.","journal-title":"J Physiol Pharmacol"},{"key":"4840_CR24","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.bpg.2012.01.016","volume":"26","author":"C Sostres","year":"2012","unstructured":"Sostres C, Gargallo CJ. Gastrointestinal lesions and complications of low-dose aspirin in the gastrointestinal tract. Best Pract Res Clin Gastroenterol. 2012;26:141\u2013151.","journal-title":"Best Pract Res Clin Gastroenterol"},{"key":"4840_CR25","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1152\/physrev.00004.2008","volume":"88","author":"JL Wallace","year":"2008","unstructured":"Wallace JL. Prostaglandins, NSAIDs, and gastric mucosal protection: why doesn\u2019t the stomach digest itself? Physiol Rev. 2008;88:1547\u20131565.","journal-title":"Physiol Rev"},{"key":"4840_CR26","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S0016-5085(99)70545-7","volume":"117","author":"B Cryer","year":"1999","unstructured":"Cryer B, Feldman M. Effects of very low dose daily, long-term aspirin therapy on gastric, duodenal, and rectal prostaglandin levels and on mucosal injury in healthy humans. Gastroenterology. 1999;117:17\u201325.","journal-title":"Gastroenterology"},{"key":"4840_CR27","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1023\/A:1022635127814","volume":"27","author":"A Lanas","year":"2003","unstructured":"Lanas A, Jim\u00e9nez P, Ferr\u00e1ndez A, et al. Selective COX-2 inhibition is associated with decreased mucosal damage induced by acid and pepsin in rabbit esophagitis. Inflammation. 2003;27:21\u201329.","journal-title":"Inflammation"},{"key":"4840_CR28","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1111\/j.1440-1746.2003.03332.x","volume":"19","author":"Y Fujiwara","year":"2004","unstructured":"Fujiwara Y, Higuchi K, Hamaguchi M, et al. Increased expression of transforming growth factor-alpha and epidermal growth factor receptors in rat chronic reflux esophagitis. J Gastroenterol Hepatol. 2004;19:521\u2013527.","journal-title":"J Gastroenterol Hepatol"},{"key":"4840_CR29","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1111\/j.1442-2050.2007.00678.x","volume":"20","author":"A Edebo","year":"2007","unstructured":"Edebo A, Vieth M, Tam W, et al. Circumferential and axial distribution of esophageal mucosal damage in reflux disease. Dis Esophagus. 2007;20:232\u2013238.","journal-title":"Dis Esophagus"},{"key":"4840_CR30","doi-asserted-by":"publisher","first-page":"1627","DOI":"10.1007\/s10620-009-0920-3","volume":"55","author":"M Nishino","year":"2010","unstructured":"Nishino M, Sugimoto M, Kodaira C, et al. Relationship between low-dose aspirin-induced gastric mucosal injury and intragastric pH in healthy volunteers. Dig Dis Sci. 2010;55:1627\u20131636. \n                        https:\/\/doi.org\/10.1007\/s10620-009-0920-3\n                        \n                    .","journal-title":"Dig Dis Sci"},{"key":"4840_CR31","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1177\/0091270010376194","volume":"51","author":"M Nishino","year":"2011","unstructured":"Nishino M, Sugimoto M, Kodaira C, et al. Preventive effects of lansoprazole and famotidine on gastric mucosal injury induced by low-dose aspirin in Helicobacter pylori-negative healthy volunteers. J Clin Pharmacol. 2011;51:1079\u20131086.","journal-title":"J Clin Pharmacol"},{"key":"4840_CR32","doi-asserted-by":"crossref","first-page":"879.e2","DOI":"10.1016\/j.cgh.2012.04.016","volume":"10","author":"T Uotani","year":"2012","unstructured":"Uotani T, Sugimoto M, Nishino M, et al. Ability of rabeprazole to prevent gastric mucosal damage from clopidogrel and low doses of aspirin depends on CYP2C19 genotype. Clin Gastroenterol Hepatol. 2012;10:879.e2\u2013885.e2.","journal-title":"Clin Gastroenterol Hepatol"}],"container-title":["Digestive Diseases and Sciences"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10620-017-4840-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-017-4840-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-017-4840-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,1,9]],"date-time":"2018-01-09T04:59:43Z","timestamp":1515473983000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10620-017-4840-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,15]]},"references-count":32,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["4840"],"URL":"https:\/\/doi.org\/10.1007\/s10620-017-4840-3","relation":{},"ISSN":["0163-2116","1573-2568"],"issn-type":[{"value":"0163-2116","type":"print"},{"value":"1573-2568","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11,15]]}}}