{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T12:19:47Z","timestamp":1792153187897,"version":"4.4.0"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2018,2,22]],"date-time":"2018-02-22T00:00:00Z","timestamp":1519257600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Dig Dis Sci"],"published-print":{"date-parts":[[2018,9]]},"DOI":"10.1007\/s10620-018-4976-9","type":"journal-article","created":{"date-parts":[[2018,2,21]],"date-time":"2018-02-21T21:21:12Z","timestamp":1519248072000},"page":"2405-2412","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":127,"title":["Gastric Per Oral Endoscopic Myotomy (G-POEM) for the Treatment of Refractory Gastroparesis: Early Experience"],"prefix":"10.1007","volume":"63","author":[{"given":"Zubair","family":"Malik","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rahul","family":"Kataria","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rani","family":"Modayil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam C.","family":"Ehrlich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ron","family":"Schey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry P.","family":"Parkman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stavros N.","family":"Stavropoulos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,2,22]]},"reference":[{"key":"4976_CR1","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1038\/ajg.2012.373","volume":"108","author":"M Camilleri","year":"2013","unstructured":"Camilleri M, Parkman HP, Shafi MA, Abell TL, Gerson L, American College of Gastroenterology. Clinical guideline: management of gastroparesis. Am J Gastroenterol. 2013;108:18\u201337.","journal-title":"Am J Gastroenterol"},{"key":"4976_CR2","doi-asserted-by":"publisher","first-page":"1251","DOI":"10.1111\/j.1365-2036.2007.03467.x","volume":"26","author":"J Arts","year":"2007","unstructured":"Arts J, Holvoet L, Caenepeel P, et al. Clinical trial: a randomized-controlled crossover study of intrapyloric injection of botulinum toxin in gastroparesis. Aliment Pharmacol Ther. 2007;26:1251\u20131258.","journal-title":"Aliment Pharmacol Ther"},{"key":"4976_CR3","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0016-5085(73)80092-7","volume":"64","author":"R Fisher","year":"1973","unstructured":"Fisher R, Cohen S. Physiological characteristics of the human pyloric sphincter. Gastroenterology. 1973;64:67\u201375.","journal-title":"Gastroenterology"},{"key":"4976_CR4","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1111\/j.1365-2982.2006.00866.x","volume":"19","author":"J Desipio","year":"2007","unstructured":"Desipio J, Friedenberg FK, Korimilli A, Richter JE, Parkman HP, Fisher RS. High-resolution solid-state manometry of the antropyloroduodenal region. Neurogastroenterol Motil. 2007;19:188\u2013195.","journal-title":"Neurogastroenterol Motil"},{"key":"4976_CR5","doi-asserted-by":"publisher","first-page":"1919","DOI":"10.1016\/0016-5085(86)90262-3","volume":"90","author":"F Mearin","year":"1986","unstructured":"Mearin F, Camilleri M, Malagelada JR. Pyloric dysfunction in diabetics with recurrent nausea and vomiting. Gastroenterology. 1986;90:1919\u20131925.","journal-title":"Gastroenterology"},{"key":"4976_CR6","doi-asserted-by":"publisher","first-page":"360","DOI":"10.1111\/apt.13053","volume":"41","author":"G Gourcerol","year":"2015","unstructured":"Gourcerol G, Tissier F, Melchior C, et al. Impaired fasting pyloric compliance in gastroparesis and the therapeutic response to pyloric dilatation. Aliment Pharmacol Ther. 2015;41:360\u2013367.","journal-title":"Aliment Pharmacol Ther"},{"key":"4976_CR7","doi-asserted-by":"publisher","first-page":"524","DOI":"10.1111\/nmo.12522","volume":"27","author":"Z Malik","year":"2015","unstructured":"Malik Z, Sankineni A, Parkman HP. Assessing pyloric sphincter pathophysiology using EndoFLIP in patients with gastroparesis. Neurogastroenterol Motil. 2015;27:524\u2013531.","journal-title":"Neurogastroenterol Motil"},{"key":"4976_CR8","doi-asserted-by":"publisher","first-page":"1653","DOI":"10.1111\/j.1572-0241.2002.05823.x","volume":"97","author":"LS Miller","year":"2002","unstructured":"Miller LS, Szych GA, Kantor SB, et al. Treatment of idiopathic gastroparesis with injection of botulinum toxin into the pyloric sphincter muscle. Am J Gastroenterol. 2002;97:1653\u20131660.","journal-title":"Am J Gastroenterol"},{"key":"4976_CR9","doi-asserted-by":"publisher","first-page":"G291","DOI":"10.1152\/ajpgi.00296.2002","volume":"285","author":"AN James","year":"2003","unstructured":"James AN, Ryan JP, Parkman HP. Inhibitory effects of botulinum toxin on pyloric and antral smooth muscle. Am J Physiol Gastrointest Liver Physiol. 2003;285:G291\u2013G297.","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"4976_CR10","doi-asserted-by":"publisher","first-page":"416","DOI":"10.1111\/j.1572-0241.2007.01676.x","volume":"103","author":"FK Friedenberg","year":"2008","unstructured":"Friedenberg FK, Palit A, Parkman HP, Hanlon A, Nelson DB. Botulinum toxin A for the treatment of delayed gastric emptying. Am J Gastroenterol.. 2008;103:416\u2013423.","journal-title":"Am J Gastroenterol."},{"key":"4976_CR11","doi-asserted-by":"publisher","first-page":"1513","DOI":"10.1007\/s11605-011-1607-6","volume":"15","author":"ML Hibbard","year":"2011","unstructured":"Hibbard ML, Dunst CM, Swanstrom LL. Laparoscopic and endoscopic pyloroplasty for gastroparesis results in sustained symptom improvement. J Gastrointest Surg. 2011;15:1513\u20131519.","journal-title":"J Gastrointest Surg"},{"key":"4976_CR12","doi-asserted-by":"publisher","first-page":"134-e80","DOI":"10.1111\/nmo.12032","volume":"25","author":"I Sarosiek","year":"2013","unstructured":"Sarosiek I, Forster J, Lin Z, Cherry S, Sarosiek J, McCallum R. The addition of pyloroplasty as a new surgical approach to enhance effectiveness of gastric electrical stimulation therapy in patients with gastroparesis. Neurogastroenterol Motil. 2013;25:134-e80.","journal-title":"Neurogastroenterol Motil"},{"key":"4976_CR13","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1007\/s11605-016-3327-4","volume":"21","author":"BR Davis","year":"2017","unstructured":"Davis BR, Sarosiek I, Bashashati M, Alvarado B, McCallum RW. The long-term efficacy and safety of pyloroplasty combined with gastric electrical stimulation therapy in gastroparesis. J Gastrointest Surg. 2017;21:222\u2013227.","journal-title":"J Gastrointest Surg"},{"key":"4976_CR14","doi-asserted-by":"publisher","first-page":"E189","DOI":"10.1055\/s-0032-1326400","volume":"45","author":"JO Clarke","year":"2013","unstructured":"Clarke JO, Sharaiha RZ, Kord Valeshabad A, Lee LA, Kalloo AN, Khashab MA. Through-the-scope transpyloric stent placement improves symptoms and gastric emptying in patients with gastroparesis. Endoscopy. 2013;45:E189\u2013E190.","journal-title":"Endoscopy"},{"key":"4976_CR15","doi-asserted-by":"publisher","first-page":"1106","DOI":"10.1016\/j.gie.2015.06.051","volume":"82","author":"MA Khashab","year":"2015","unstructured":"Khashab MA, Besharati S, Ngamruengphong S, et al. Refractory gastroparesis can be successfully managed with endoscopic transpyloric stent placement and fixation (with video). Gastrointest Endosc. 2015;82:1106\u20131109.","journal-title":"Gastrointest Endosc"},{"key":"4976_CR16","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/S0016-5107(80)73249-2","volume":"26","author":"JA Ortega","year":"1980","unstructured":"Ortega JA, Madureri V, Perez L. Endoscopic myotomy in the treatment of achalasia. Gastrointest Endosc. 1980;26:8\u201310.","journal-title":"Gastrointest Endosc"},{"key":"4976_CR17","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1055\/s-0029-1244080","volume":"42","author":"H Inoue","year":"2010","unstructured":"Inoue H, Minami H, Kobayashi Y, et al. Peroral endoscopic myotomy (POEM) for esophageal achalasia. Endoscopy. 2010;42:265\u2013271.","journal-title":"Endoscopy"},{"key":"4976_CR18","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1055\/s-0031-1291475","volume":"44","author":"M Kawai","year":"2012","unstructured":"Kawai M, Peretta S, Burckhardt O, Dallemagne B, Marescaux J, Tanigawa N. Endoscopic pyloromyotomy: a new concept of minimally invasive surgery for pyloric stenosis. Endoscopy. 2012;44:169\u2013173.","journal-title":"Endoscopy"},{"key":"4976_CR19","doi-asserted-by":"publisher","first-page":"764","DOI":"10.1016\/j.gie.2013.07.019","volume":"78","author":"MA Khashab","year":"2013","unstructured":"Khashab MA, Stein E, Clarke JO, et al. Gastric peroral endoscopic myotomy for refractory gastroparesis: first human endoscopic pyloromyotomy (with video). Gastrointest Endosc. 2013;78:764\u2013768.","journal-title":"Gastrointest Endosc"},{"key":"4976_CR20","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1016\/j.gie.2016.06.048","volume":"85","author":"MA Khashab","year":"2017","unstructured":"Khashab MA, Ngamruengphong S, Carr-Locke D, et al. Gastric per-oral endoscopic myotomy for refractory gastroparesis: Results from the first multicenter study on endoscopic pyloromyotomy (with video). Gastrointest Endosc. 2017;85:123\u2013128.","journal-title":"Gastrointest Endosc"},{"key":"4976_CR21","doi-asserted-by":"publisher","first-page":"1737","DOI":"10.1007\/s11136-004-9567-x","volume":"13","author":"AM Rentz","year":"2004","unstructured":"Rentz AM, Kahrilas P, Stanghellini V, et al. Development and psychometric evaluation of the patient assessment of upper gastrointestinal symptom severity index (PAGI-SYM) in patients with upper gastrointestinal disorders. Qual Life Res. 2004;13:1737\u20131749.","journal-title":"Qual Life Res"},{"key":"4976_CR22","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1046\/j.1365-2036.2003.01612.x","volume":"18","author":"DA Revicki","year":"2003","unstructured":"Revicki DA, Rentz AM, Dubois D, et al. Development and validation of a patient-assessed gastroparesis symptom severity measure: the gastroparesis cardinal symptom index. Aliment Pharmacol Ther. 2003;18:141\u2013150.","journal-title":"Aliment Pharmacol Ther"},{"key":"4976_CR23","doi-asserted-by":"publisher","first-page":"2072","DOI":"10.1007\/s10620-007-0124-7","volume":"53","author":"JL Maranki","year":"2008","unstructured":"Maranki JL, Lytes V, Meilahn JE, et al. Predictive factors for clinical improvement with Enterra gastric electric stimulation treatment for refractory gastroparesis. Dig Dis Sci. 2008;53:2072\u20132078.","journal-title":"Dig Dis Sci"},{"key":"4976_CR24","doi-asserted-by":"publisher","first-page":"2640","DOI":"10.1001\/jama.2013.282833","volume":"310","author":"HP Parkman","year":"2013","unstructured":"Parkman HP, Van Natta ML, Abell TL, et al. Effect of nortriptyline on symptoms of idiopathic gastroparesis: the NORIG randomized clinical trial. JAMA.. 2013;310:2640\u20132649.","journal-title":"JAMA."},{"key":"4976_CR25","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1007\/s00464-014-3720-6","volume":"29","author":"E Shlomovitz","year":"2015","unstructured":"Shlomovitz E, Pescarus R, Cassera MA, et al. Early human experience with per-oral endoscopic pyloromyotomy (POP). Surg Endosc. 2015;29:543\u2013551.","journal-title":"Surg Endosc"},{"key":"4976_CR26","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1111\/apt.14132","volume":"46","author":"JM Gonzalez","year":"2017","unstructured":"Gonzalez JM, Benezech A, Vitton V, Barthet M. G-POEM with antro-pyloromyotomy for the treatment of refractory gastroparesis: mid-term follow-up and factors predicting outcome. Alim Pharm Ther. 2017;46:364\u2013370.","journal-title":"Alim Pharm Ther"},{"key":"4976_CR27","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1016\/j.gie.2017.01.031","volume":"86","author":"S Dacha","year":"2017","unstructured":"Dacha S, Mekaroonkamol P, Li L, et al. Outcomes and quality-of-life assessment after gastric per-oral endoscopic pyloromyotomy (with video). Gastrointest Endosc. 2017;86:282\u2013292.","journal-title":"Gastrointest Endosc"},{"key":"4976_CR28","doi-asserted-by":"publisher","first-page":"5381","DOI":"10.1007\/s00464-017-5619-5","volume":"31","author":"JH Rodriguez","year":"2017","unstructured":"Rodriguez JH, Haskins IN, Strong AT, et al. Per oral endoscopic pyloromyotomy for refractory gastroparesis: initial results from a single institution. Surg Endosc. 2017;31:5381\u20135388.","journal-title":"Surg Endosc"},{"key":"4976_CR29","doi-asserted-by":"crossref","unstructured":"Jacques J, Pagnon L, Hure F, Legros R, Charissoux A, Fauchais AL, Palat S, Ducrotte P, Martin B, Fontaine S, Bonbaddi NE, Clement MP, Sautereau D, Loustaud-Ratti V, Gourcerol G, Monteil J. Per-oral endoscopic pyloromyotomy is efficacious and safe for refractory gastroparesis: the first prospective study with a concomitant assessment of pyloric function. Gut 2018 (in press).","DOI":"10.1055\/a-0628-6639"},{"key":"4976_CR30","doi-asserted-by":"publisher","first-page":"758","DOI":"10.1111\/nmo.12772","volume":"28","author":"WJ Snape","year":"2016","unstructured":"Snape WJ, Lin MS, Agarwal N, Shaw RE. Evaluation of the pylorus with concurrent intraluminal pressure and EndoFLIP in patients with nausea and vomiting. Neurogastroenterol Motil. 2016;28:758\u2013764.","journal-title":"Neurogastroenterol Motil"},{"key":"4976_CR31","doi-asserted-by":"publisher","first-page":"2270","DOI":"10.1023\/A:1026660921776","volume":"44","author":"MG Patti","year":"1999","unstructured":"Patti MG, Feo CV, Arcerito M, et al. Effects of previous treatment on results of laparoscopic Heller myotomy for achalasia. Dig Dis Sci. 1999;44:2270\u20132276.","journal-title":"Dig Dis Sci"}],"container-title":["Digestive Diseases and Sciences"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10620-018-4976-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-018-4976-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-018-4976-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,11]],"date-time":"2019-10-11T06:15:27Z","timestamp":1570774527000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10620-018-4976-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2,22]]},"references-count":31,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2018,9]]}},"alternative-id":["4976"],"URL":"https:\/\/doi.org\/10.1007\/s10620-018-4976-9","relation":{},"ISSN":["0163-2116","1573-2568"],"issn-type":[{"value":"0163-2116","type":"print"},{"value":"1573-2568","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,2,22]]},"assertion":[{"value":"12 July 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 February 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 February 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"None.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}