{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T22:36:01Z","timestamp":1789684561537,"version":"4.0.1"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2018,3,7]],"date-time":"2018-03-07T00:00:00Z","timestamp":1520380800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2018,3,7]],"date-time":"2018-03-07T00:00:00Z","timestamp":1520380800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["P50CA150964"],"award-info":[{"award-number":["P50CA150964"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["P30CA43703"],"award-info":[{"award-number":["P30CA43703"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["P50CA130810"],"award-info":[{"award-number":["P50CA130810"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["U01CA086400"],"award-info":[{"award-number":["U01CA086400"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["P30CA046592"],"award-info":[{"award-number":["P30CA046592"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["U01CA181770"],"award-info":[{"award-number":["U01CA181770"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["P30DK097948"],"award-info":[{"award-number":["P30DK097948"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Dig Dis Sci"],"published-print":{"date-parts":[[2018,6]]},"DOI":"10.1007\/s10620-018-5001-z","type":"journal-article","created":{"date-parts":[[2018,3,7]],"date-time":"2018-03-07T03:52:58Z","timestamp":1520394778000},"page":"1449-1453","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Evaluation of Patients with an Apparent False Positive Stool DNA Test: The Role of Repeat Stool DNA Testing"],"prefix":"10.1007","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1019-4326","authenticated-orcid":false,"given":"Gregory S.","family":"Cooper","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanford D.","family":"Markowitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengyi","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Missy","family":"Tuck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph E.","family":"Willis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barry M.","family":"Berger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dean E.","family":"Brenner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,3,7]]},"reference":[{"key":"5001_CR1","doi-asserted-by":"publisher","first-page":"2564","DOI":"10.1001\/jama.2016.5989","volume":"315","author":"K Bibbins-Domingo","year":"2016","unstructured":"US Preventive Services Task Force, Bibbins-Domingo K, Grossman DC, Curry SJ, et al. Screening for colorectal cancer: US Preventive Services Task Force recommendation statement. JAMA.. 2016;315:2564\u20132575.","journal-title":"JAMA."},{"key":"5001_CR2","doi-asserted-by":"publisher","first-page":"1287","DOI":"10.1056\/NEJMoa1311194","volume":"370","author":"TF Imperiale","year":"2014","unstructured":"Imperiale TF, Ransohoff DF, Itzkowitz SH, et al. Multi-target stool DNA testing for colorectal cancer screening. N Engl J Med. 2014;370:1287\u20131297.","journal-title":"N Engl J Med"},{"key":"5001_CR3","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1055\/s-2007-995618","volume":"40","author":"D Heresbach","year":"2008","unstructured":"Heresbach D, Barrioz T, Lapalus MG, et al. Miss rate for colorectal neoplastic polyps: a prospective multicenter study of back-to-back video colonoscopies. Endoscopy. 2008;40:284\u2013290.","journal-title":"Endoscopy"},{"key":"5001_CR4","doi-asserted-by":"publisher","first-page":"1375","DOI":"10.1038\/ajg.2014.171","volume":"109","author":"S Singh","year":"2014","unstructured":"Singh S, Singh PP, Murad MH, Singh H, Samadder NJ. Prevalence, risk factors and outcomes of interval colorectal cancers: a systematic review and meta-analysis. Am J Gastroenterol. 2014;109:1375\u20131389.","journal-title":"Am J Gastroenterol"},{"key":"5001_CR5","doi-asserted-by":"publisher","first-page":"2623","DOI":"10.1002\/cncr.26558","volume":"118","author":"JB Kisiel","year":"2012","unstructured":"Kisiel JB, Yab TC, Taylor WR, et al. Stool DNA testing for the detection of pancreatic cancer: assessment of methylation marker candidates. Cancer. 2012;118:2623\u20132631.","journal-title":"Cancer"},{"key":"5001_CR6","doi-asserted-by":"publisher","first-page":"614","DOI":"10.1158\/1055-9965.EPI-16-0800","volume":"26","author":"TG Cotter","year":"2017","unstructured":"Cotter TG, Burger KN, Devens ME, et al. Long-term follow-up of patients having false positive multi-target stool DNA tests after negative screening colonoscopy. The LONG-HAUL cohort study. Cancer Epidemiol Biomark Prev. 2017;26:614\u2013621.","journal-title":"Cancer Epidemiol Biomark Prev"},{"key":"5001_CR7","unstructured":"FDA Summary of Safety and Effectiveness, PMA P130017b August 2014, page 9. \n                    www.fda.cov\n                    \n                  . Accessed 16.02.2018."},{"key":"5001_CR8","doi-asserted-by":"publisher","first-page":"573","DOI":"10.7326\/0003-4819-147-8-200710160-00010","volume":"147","author":"E von Elm","year":"2007","unstructured":"von Elm E, Altman DG, Egger M, Pocock SJ, G\u00f8tzsche PC, Vandenbroucke JP. The strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies. Ann Intern Med. 2007;147:573\u2013577.","journal-title":"Ann Intern Med"},{"key":"5001_CR9","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1038\/ajg.2014.385","volume":"110","author":"DK Rex","year":"2015","unstructured":"Rex DK, Schoenfeld PS, Cohen J, et al. Quality indicators for colonoscopy. Am J Gastroenterol.. 2015;110:72\u201390.","journal-title":"Am J Gastroenterol."},{"key":"5001_CR10","doi-asserted-by":"publisher","first-page":"2656","DOI":"10.1038\/ajg.2010.315","volume":"105","author":"JT Hetzel","year":"2010","unstructured":"Hetzel JT, Huang CS, Coukos JA, et al. Variation in the detection of serrated polyps in an average risk colorectal cancer screening cohort. Am J Gastroenterol. 2010;105:2656\u20132664.","journal-title":"Am J Gastroenterol"},{"key":"5001_CR11","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1016\/j.cgh.2010.09.013","volume":"9","author":"CJ Kahi","year":"2011","unstructured":"Kahi CJ, Hewett DG, Norton DL, et al. Prevalence and variable detection of proximal colon serrated polyps during screening colonoscopy. Clin Gastroenterol Hepatol. 2011;9:42\u201346.","journal-title":"Clin Gastroenterol Hepatol"},{"key":"5001_CR12","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1016\/j.gie.2016.11.012","volume":"85","author":"DH Johnson","year":"2017","unstructured":"Johnson DH, Kisiel JB, Burger KW, et al. Multitarget stool DNA test: clinical performance and impact on yield and quality of colonoscopy for colorectal cancer screening. Gastrointest Endosc. 2017;85:657\u2013665.","journal-title":"Gastrointest Endosc"},{"key":"5001_CR13","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1016\/j.gie.2014.06.020","volume":"81","author":"MA Manfredi","year":"2015","unstructured":"Manfredi MA, Abu Dayyeh BK, Bhat YM, et al. Electronic chromoendoscopy. Gastrointest Endosc. 2015;81:249\u2013261.","journal-title":"Gastrointest Endosc"},{"key":"5001_CR14","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1053\/j.gastro.2017.05.013","volume":"153","author":"DK Rex","year":"2017","unstructured":"Rex DK, Boland CR, Dominitz JA, et al. Colorectal cancer screening: recommendations for physicians and patients from the U.S. Multi-Society Task Force on Colorectal Cancer. Gastroenterology. 2017;153:307\u2013323.","journal-title":"Gastroenterology"}],"container-title":["Digestive Diseases and Sciences"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10620-018-5001-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-018-5001-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-018-5001-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,17]],"date-time":"2020-05-17T14:18:43Z","timestamp":1589725123000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10620-018-5001-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3,7]]},"references-count":14,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2018,6]]}},"alternative-id":["5001"],"URL":"https:\/\/doi.org\/10.1007\/s10620-018-5001-z","relation":{},"ISSN":["0163-2116","1573-2568"],"issn-type":[{"value":"0163-2116","type":"print"},{"value":"1573-2568","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,3,7]]},"assertion":[{"value":"19 December 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 February 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 March 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"Barry M. Berger, MD, is a full-time employee of Exact Sciences, Inc, the manufacturer of the stool DNA technology used in this study. None of the other authors have conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}