{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T05:40:17Z","timestamp":1781588417719,"version":"3.54.5"},"reference-count":12,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2019,2,25]],"date-time":"2019-02-25T00:00:00Z","timestamp":1551052800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Dig Dis Sci"],"published-print":{"date-parts":[[2019,8]]},"DOI":"10.1007\/s10620-019-05545-2","type":"journal-article","created":{"date-parts":[[2019,2,25]],"date-time":"2019-02-25T02:34:56Z","timestamp":1551062096000},"page":"2206-2213","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Multiple Rapid Swallows (MRS) Complements Single-Swallow (SS) Analysis for High-Resolution Esophageal Manometry (HREM)"],"prefix":"10.1007","volume":"64","author":[{"given":"Andrew","family":"Leopold","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daohai","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajiv","family":"Bhuta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rahul","family":"Kataria","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoning","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asad","family":"Jehangir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martha","family":"Harrison","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Friedenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zubair","family":"Malik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ron","family":"Schey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4904-4891","authenticated-orcid":false,"given":"Henry P.","family":"Parkman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,2,25]]},"reference":[{"key":"5545_CR1","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1136\/gut.2007.133298","volume":"57","author":"AJ Bredenoord","year":"2008","unstructured":"Bredenoord AJ, Fox MR. Oesophageal high-resolution manometry: moving from research into clinical practice. Gut. 2008;57:405\u2013423.","journal-title":"Gut"},{"key":"5545_CR2","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1111\/nmo.12477","volume":"27","author":"International High Resolution Manometry Working Group","year":"2015","unstructured":"International High Resolution Manometry Working Group. The Chicago classification of esophageal motility disorders, v3.0. Neurogastroenterol Motil. 2015;27:160\u2013174.","journal-title":"Neurogastroenterol Motil"},{"key":"5545_CR3","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1111\/nmo.12071","volume":"25","author":"CP Gyawali","year":"2013","unstructured":"Gyawali CP, Bredenoord AJ, Conklin JL, et al. Evaluation of esophageal motor function in clinical practice. Neurogastroenterol Motil. 2013;25:99\u2013133.","journal-title":"Neurogastroenterol Motil"},{"key":"5545_CR4","doi-asserted-by":"publisher","first-page":"1706","DOI":"10.1038\/ajg.2013.289","volume":"108","author":"A Shaker","year":"2013","unstructured":"Shaker A, Stoikes N, Drapekin J, Kushnir V, Brunt LM, Gyawali P. Multiple rapid swallow responses during esophageal high-resolution manometry reflect esophageal body peristaltic reserve. Am J Gastroenterol. 2013;108:1706\u20131712.","journal-title":"Am J Gastroenterol"},{"key":"5545_CR5","doi-asserted-by":"publisher","first-page":"410","DOI":"10.5056\/jnm18038","volume":"24","author":"P Woodland","year":"2018","unstructured":"Woodland P, Gabieta-Sonmez S, Arguero J, et al. 200\u00a0mL rapid drink challenge during high-resolution manometry best predicts objective esophagogastric junction obstruction and correlates with symptom severity. Neurogastroenterol Motil. 2018;24:410.","journal-title":"Neurogastroenterol Motil"},{"key":"5545_CR6","doi-asserted-by":"publisher","first-page":"e12902","DOI":"10.1111\/nmo.12902","volume":"29","author":"D Ang","year":"2017","unstructured":"Ang D, Hollenstein M, Misselwitz B, et al. Rapid drink challenge in high-resolution manometry: an adjunctive test for detection of esophageal motility disorders. Neurogastroenterol Motil. 2017;29:e12902.","journal-title":"Neurogastroenterol Motil"},{"key":"5545_CR7","doi-asserted-by":"publisher","first-page":"6","DOI":"10.5056\/jnm.2012.18.1.6","volume":"18","author":"D Sifrim","year":"2012","unstructured":"Sifrim D, Jafari J. Deglutitive inhibition, latency between swallow and esophageal contractions and primary esophageal motor disorders. Neurogastroenterol Motil. 2012;18:6\u201312.","journal-title":"Neurogastroenterol Motil"},{"key":"5545_CR8","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1111\/j.1365-2982.2006.00886.x","volume":"19","author":"D Savojardo","year":"2007","unstructured":"Savojardo D, Mangano M, Cant\u00fa P, Penagini R. Multiple rapid swallowing in idiopathic achalasia: evidence for patients\u2019 heterogeneity. Neurogastroenterol Motil. 2007;19:263\u2013269.","journal-title":"Neurogastroenterol Motil"},{"key":"5545_CR9","doi-asserted-by":"publisher","first-page":"646","DOI":"10.1111\/nmo.12310","volume":"26","author":"LH Price","year":"2014","unstructured":"Price LH, Li Y, Gyawali CP. Reproducibility patterns of multiple rapid swallows during high resolution esophageal manometry provide insights into esophageal pathophysiology. Neurogastroenterol Motil. 2014;26:646\u2013653.","journal-title":"Neurogastroenterol Motil"},{"key":"5545_CR10","doi-asserted-by":"publisher","first-page":"718","DOI":"10.1111\/j.1365-2982.2009.01273.x","volume":"21","author":"F Fornari","year":"2009","unstructured":"Fornari F, Bravi I, Penagini R, Tack J, Sifrim D. Multiple rapid swallowing: a complementary test during standard oesophageal manometry. Neurogastroenterol Motil. 2009;21:718\u2013725.","journal-title":"Neurogastroenterol Motil"},{"key":"5545_CR11","doi-asserted-by":"publisher","first-page":"3401","DOI":"10.1007\/s00464-012-2350-0","volume":"26","author":"ND Stoikes","year":"2012","unstructured":"Stoikes ND. The value of multiple rapid swallows during preoperative esophageal manometry before laparoscopic antireflux surgery. Surg Endosc. 2012;26:3401\u20133407.","journal-title":"Surg Endosc"},{"key":"5545_CR12","doi-asserted-by":"publisher","first-page":"e489","DOI":"10.1111\/j.1365-2982.2012.01989.x","volume":"24","author":"Y Xiao","year":"2012","unstructured":"Xiao Y, Nicod\u00e8me F, Kahrilas PJ, Roman S, Lin Z, Pandolfino JE. Optimizing the swallow protocol of clinical high resolution esophageal manometry studies. Neurogastroenterol Motil. 2012;24:e489\u2013e496.","journal-title":"Neurogastroenterol Motil"}],"container-title":["Digestive Diseases and Sciences"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10620-019-05545-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-019-05545-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-019-05545-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,2,24]],"date-time":"2020-02-24T19:09:08Z","timestamp":1582571348000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10620-019-05545-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,25]]},"references-count":12,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2019,8]]}},"alternative-id":["5545"],"URL":"https:\/\/doi.org\/10.1007\/s10620-019-05545-2","relation":{},"ISSN":["0163-2116","1573-2568"],"issn-type":[{"value":"0163-2116","type":"print"},{"value":"1573-2568","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,2,25]]},"assertion":[{"value":"14 July 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 February 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 February 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"No conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of Interest"}}]}}