{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T22:55:13Z","timestamp":1781650513074,"version":"3.54.5"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2019,9,16]],"date-time":"2019-09-16T00:00:00Z","timestamp":1568592000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,9,16]],"date-time":"2019-09-16T00:00:00Z","timestamp":1568592000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Dig Dis Sci"],"published-print":{"date-parts":[[2020,4]]},"DOI":"10.1007\/s10620-019-05835-9","type":"journal-article","created":{"date-parts":[[2019,9,16]],"date-time":"2019-09-16T15:02:46Z","timestamp":1568646166000},"page":"1212-1222","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Non-occlusive Mesenteric Ischemia as a Fatal Complication in Acute Pancreatitis: A Case Series"],"prefix":"10.1007","volume":"65","author":[{"given":"Cynthia","family":"Reichling","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leda","family":"Nobile","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"Pezzullo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Navez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Najla","family":"Bachir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicky","family":"D\u2019Haene","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Calliope","family":"Maris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Musala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Fernandez Y. Viesca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Grimaldi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myriam","family":"Delhaye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,9,16]]},"reference":[{"key":"5835_CR1","doi-asserted-by":"publisher","first-page":"1683","DOI":"10.1007\/s10620-017-4510-5","volume":"62","author":"JD Machicado","year":"2017","unstructured":"Machicado JD, Yadav D. Epidemiology of recurrent acute and chronic pancreatitis: similarities and differences. Dig Dis Sci. 2017;62:1683\u20131691. \nhttps:\/\/doi.org\/10.1007\/s10620-017-4510-5\n\n.","journal-title":"Dig Dis Sci"},{"key":"5835_CR2","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1097\/01.mpa.0000236733.31617.52","volume":"33","author":"D Yadav","year":"2006","unstructured":"Yadav D, Lowenfels AB. Trends in the epidemiology of the first attack of acute pancreatitis: a systematic review. Pancreas. 2006;33:323\u2013330.","journal-title":"Pancreas"},{"key":"5835_CR3","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1097\/01.mpa.0000236727.16370.99","volume":"33","author":"CF Frey","year":"2006","unstructured":"Frey CF, Zhou H, Harvey DJ, White RH. The incidence and case-fatality rates of acute biliary, alcoholic, and idiopathic pancreatitis in California, 1994\u20132001. Pancreas. 2006;33:336\u2013344.","journal-title":"Pancreas"},{"key":"5835_CR4","doi-asserted-by":"publisher","first-page":"932","DOI":"10.1097\/SLA.0000000000002612","volume":"269","author":"H Karjula","year":"2019","unstructured":"Karjula H, Saarela A, Ohtonen P, et al. Long-term outcome and causes of death for working-age patients hospitalized due to acute pancreatitis with a median follow-up of 10 years. Ann Surg. 2019;269:932\u2013936.","journal-title":"Ann Surg"},{"key":"5835_CR5","doi-asserted-by":"publisher","first-page":"2024","DOI":"10.1136\/gutjnl-2016-313595","volume":"66","author":"SM van Dijk","year":"2017","unstructured":"van Dijk SM, Hallensleben NDL, van Santvoort HC, et al. Acute pancreatitis: recent advances through randomised trials. Gut. 2017;66:2024\u20132032.","journal-title":"Gut"},{"key":"5835_CR6","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1097\/00006676-200301000-00002","volume":"26","author":"G Flati","year":"2003","unstructured":"Flati G, Andr\u00e9n-Sandberg A, La Pinta M, et al. Potentially fatal bleeding in acute pancreatitis: pathophysiology, prevention, and treatment. Pancreas. 2003;26:8\u201314.","journal-title":"Pancreas"},{"key":"5835_CR7","doi-asserted-by":"publisher","first-page":"1073","DOI":"10.1111\/j.1445-2197.2005.03607.x","volume":"75","author":"RM Mendelson","year":"2005","unstructured":"Mendelson RM, Anderson J, Marshall M, Ramsay D. Vascular complications of pancreatitis. ANZ J Surg. 2005;75:1073\u20131079.","journal-title":"ANZ J Surg"},{"key":"5835_CR8","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1159\/000071770","volume":"3","author":"M Hirota","year":"2003","unstructured":"Hirota M, Inoue K, Kimura Y, et al. Non-occlusive mesenteric ischemia and its associated intestinal gangrene in acute pancreatitis. Pancreatology. 2003;3:316\u2013322.","journal-title":"Pancreatology"},{"key":"5835_CR9","doi-asserted-by":"publisher","first-page":"925","DOI":"10.1016\/j.suc.2013.04.002","volume":"93","author":"JL Bobadilla","year":"2013","unstructured":"Bobadilla JL. Mesenteric ischemia. Surg Clin North Am. 2013;93:925\u2013940.","journal-title":"Surg Clin North Am"},{"key":"5835_CR10","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1002\/bjs.4459","volume":"91","author":"IG Schoots","year":"2004","unstructured":"Schoots IG, Koffeman GI, Legemate DA, Levi M, van Gulik TM. Systematic review of survival after acute mesenteric ischaemia according to disease aetiology. Br J Surg. 2004;91:17\u201327.","journal-title":"Br J Surg"},{"key":"5835_CR11","doi-asserted-by":"publisher","first-page":"767","DOI":"10.1148\/radiology.156.3.4023241","volume":"156","author":"EJ Balthazar","year":"1985","unstructured":"Balthazar EJ, Ranson JH, Naidich DP, Megibow AJ, Caccavale R, Cooper MM. Acute pancreatitis: prognostic value of CT. Radiology. 1985;156:767\u2013772.","journal-title":"Radiology"},{"key":"5835_CR12","doi-asserted-by":"publisher","first-page":"1261","DOI":"10.2214\/ajr.183.5.1831261","volume":"183","author":"KJ Mortele","year":"2004","unstructured":"Mortele KJ, Wiesner W, Intriere L, et al. A modified CT severity index for evaluating acute pancreatitis: improved correlation with patient outcome. Am J Roentgenol. 2004;183:1261\u20131265.","journal-title":"Am J Roentgenol"},{"key":"5835_CR13","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/kisup.2012.1","volume":"2","author":"Kidney Disease Improving Global Outcomes (KDIGO)","year":"2012","unstructured":"Kidney Disease Improving Global Outcomes (KDIGO). Clinical practice guideline for acute kidney injury. Kidney Int Suppl. 2012;2:1\u2013138.","journal-title":"Kidney Int Suppl"},{"key":"5835_CR14","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1007\/s11547-014-0460-6","volume":"120","author":"MA Mazzei","year":"2015","unstructured":"Mazzei MA, Volterrani L. Nonocclusive mesenteric ischaemia: think about it. Radiol Med. 2015;120:85\u201395.","journal-title":"Radiol Med"},{"key":"5835_CR15","doi-asserted-by":"publisher","first-page":"707","DOI":"10.1007\/BF01709751","volume":"22","author":"JL Vincent","year":"1996","unstructured":"Vincent JL, Moreno R, Takala J, et al. The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction\/failure. Intensive Care Med. 1996;22:707\u2013710.","journal-title":"Intensive Care Med"},{"key":"5835_CR16","doi-asserted-by":"publisher","first-page":"1345","DOI":"10.1007\/s00134-005-2763-5","volume":"31","author":"RP Moreno","year":"2005","unstructured":"Moreno RP, Metnitz PGH, Almeida E, et al. SAPS 3\u2014from evaluation of the patient to evaluation of the intensive care unit. Part 2: development of a prognostic model for hospital mortality at ICU admission. Intensive Care Med. 2005;31:1345\u20131355.","journal-title":"Intensive Care Med"},{"key":"5835_CR17","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1067\/mva.2002.120373","volume":"35","author":"WM Park","year":"2002","unstructured":"Park WM, Gloviczki P, Cherry KJ, et al. Contemporary management of acute mesenteric ischemia: factors associated with survival. J Vasc Surg. 2002;35:445\u2013452.","journal-title":"J Vasc Surg"},{"key":"5835_CR18","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1007\/s00068-016-0634-0","volume":"42","author":"JVT Tilsed","year":"2016","unstructured":"Tilsed JVT, Casamassima A, Kurihara H, et al. ESTES guidelines: acute mesenteric ischaemia. Eur J Trauma Emerg Surg. 2016;42:253\u2013270.","journal-title":"Eur J Trauma Emerg Surg"},{"key":"5835_CR19","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1186\/s13613-016-0213-x","volume":"6","author":"S Bourcier","year":"2016","unstructured":"Bourcier S, Oudjit A, Goudard G, et al. Diagnosis of non-occlusive acute mesenteric ischemia in the intensive care unit. Ann Intensive Care. 2016;6:112.","journal-title":"Ann Intensive Care"},{"key":"5835_CR20","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1016\/S0002-9610(97)89619-5","volume":"171","author":"TJ Howard","year":"1996","unstructured":"Howard TJ, Plaskon LA, Wiebke EA, Wilcox MG, Madura JA. Nonocclusive mesenteric ischemia remains a diagnostic dilemma. Am J Surg. 1996;171:405\u2013408.","journal-title":"Am J Surg"},{"key":"5835_CR21","doi-asserted-by":"publisher","first-page":"394","DOI":"10.1016\/S0002-9610(97)89617-1","volume":"171","author":"K Takeda","year":"1996","unstructured":"Takeda K, Matsuno S, Sunamura M, Kakugawa Y. Continuous regional arterial infusion of protease inhibitor and antibiotics in acute necrotizing pancreatitis. Am J Surg. 1996;171:394\u2013398.","journal-title":"Am J Surg"},{"key":"5835_CR22","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1007\/s00261-008-9392-8","volume":"34","author":"AJ Aschoff","year":"2009","unstructured":"Aschoff AJ, Stuber G, Becker BW, et al. Evaluation of acute mesenteric ischemia: accuracy of biphasic mesenteric multi-detector CT angiography. Abdom Imaging. 2009;34:345\u2013357.","journal-title":"Abdom Imaging"},{"key":"5835_CR23","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1186\/s13017-017-0150-5","volume":"12","author":"M Bala","year":"2017","unstructured":"Bala M, Kashuk J, Moore EE, et al. Acute mesenteric ischemia: guidelines of the World Society of Emergency Surgery. World J Emerg Surg. 2017;12:38.","journal-title":"World J Emerg Surg"},{"key":"5835_CR24","doi-asserted-by":"publisher","first-page":"959","DOI":"10.1056\/NEJMra1503884","volume":"374","author":"DG Clair","year":"2016","unstructured":"Clair DG, Beach JM. Mesenteric ischemia. N Engl J Med. 2016;374:959\u2013968.","journal-title":"N Engl J Med"},{"key":"5835_CR25","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/S0039-6109(16)45626-4","volume":"72","author":"A Patel","year":"1992","unstructured":"Patel A, Kaleya RN, Sammartano RJ. Pathophysiology of mesenteric ischemia. Surg Clin North Am. 1992;72:31\u201341.","journal-title":"Surg Clin North Am"},{"key":"5835_CR26","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1016\/0002-9610(67)90159-6","volume":"114","author":"LF Williams","year":"1967","unstructured":"Williams LF, Anastasia LF, Hasiotis CA, Bosniak MA, Byrne JJ. Nonocclusive mesenteric infarction. Am J Surg. 1967;114:376\u2013381.","journal-title":"Am J Surg"},{"key":"5835_CR27","doi-asserted-by":"publisher","first-page":"1054","DOI":"10.1001\/archinte.164.10.1054","volume":"164","author":"WA Oldenburg","year":"2004","unstructured":"Oldenburg WA, Lau LL, Rodenberg TJ, Edmonds HJ, Burger CD. Acute mesenteric ischemia: a clinical review. Arch Intern Med. 2004;164:1054\u20131062.","journal-title":"Arch Intern Med"},{"key":"5835_CR28","first-page":"227","volume":"81","author":"JE Gottlieb","year":"1986","unstructured":"Gottlieb JE, Menashe PI, Cruz E. Gastrointestinal complications in critically ill patients: the intensivists\u2019 overview. Am J Gastroenterol. 1986;81:227\u2013238.","journal-title":"Am J Gastroenterol"},{"key":"5835_CR29","first-page":"848","volume":"82","author":"SJ Boley","year":"1977","unstructured":"Boley SJ, Sprayregan S, Siegelman SS, Veith FJ. Initial results from an agressive roentgenological and surgical approach to acute mesenteric ischemia. Surgery. 1977;82:848\u2013855.","journal-title":"Surgery"},{"key":"5835_CR30","doi-asserted-by":"publisher","first-page":"714","DOI":"10.1007\/s00261-012-9975-2","volume":"38","author":"IB Oliva","year":"2013","unstructured":"Oliva IB, Davarpanah AH, Rybicki FJ, et al. ACR Appropriateness criteria\u00ae imaging of mesenteric ischemia. Abdom Imaging. 2013;38:714\u2013719.","journal-title":"Abdom Imaging"},{"key":"5835_CR31","doi-asserted-by":"publisher","first-page":"1179","DOI":"10.1007\/s00330-001-1220-2","volume":"12","author":"M Trompeter","year":"2002","unstructured":"Trompeter M, Brazda T, Remy CT, Vestring T, Reimer P. Non-occlusive mesenteric ischemia: etiology, diagnosis, and interventional therapy. Eur Radiol. 2002;12:1179\u20131187.","journal-title":"Eur Radiol"},{"key":"5835_CR32","doi-asserted-by":"publisher","first-page":"e463","DOI":"10.1161\/CIRCULATIONAHA.106.174526","volume":"113","author":"AT Hirsch","year":"2006","unstructured":"Hirsch AT, Haskal ZJ, Hertzer NR, et al. ACC\/AHA 2005 Practice Guidelines for the management of patients with peripheral arterial disease (lower extremity, renal, mesenteric, and abdominal aortic): a collaborative report from the American Association for Vascular Surgery\/Society for Vascular Surgery, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, Society of Interventional Radiology, and the ACC\/AHA Task Force on Practice Guidelines (Writing Committee to Develop Guidelines for the Management of Patients With Peripheral Arterial Disease): endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation; National Heart, Lung, and Blood Institute; Society for Vascular Nursing; TransAtlantic Inter-Society Consensus; and Vascular Disease Foundation. Circulation. 2006;113:e463\u2013e654.","journal-title":"Circulation"},{"key":"5835_CR33","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1097\/00024382-200115050-00001","volume":"15","author":"PM Reilly","year":"2001","unstructured":"Reilly PM, Wilkins KB, Fuh KC, Haglund U, Bulkley GB. The mesenteric hemodynamic response to circulatory shock: an overview. Shock. 2001;15:329\u2013343.","journal-title":"Shock"},{"key":"5835_CR34","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1097\/01.ccx.0000216584.72427.e4","volume":"12","author":"CA Woolsey","year":"2006","unstructured":"Woolsey CA, Coopersmith CM. Vasoactive drugs and the gut: is there anything new? Curr Opin Crit Care. 2006;12:155\u2013159.","journal-title":"Curr Opin Crit Care"},{"key":"5835_CR35","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1097\/00000658-200107000-00016","volume":"234","author":"JE Meilahn","year":"2001","unstructured":"Meilahn JE, Morris JB, Ceppa EP, Bulkley GB. Effect of prolonged selective intramesenteric arterial vasodilator therapy on intestinal viability after acute segmental mesenteric vascular occlusion. Ann Surg. 2001;234:107\u2013115.","journal-title":"Ann Surg"},{"key":"5835_CR36","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1097\/01.sla.0000263157.59422.76","volume":"246","author":"A Mitsuyoshi","year":"2007","unstructured":"Mitsuyoshi A, Obama K, Shinkura N, Ito T, Zaima M. Survival in nonocclusive mesenteric ischemia: early diagnosis by multidetector row computed tomography and early treatment with continuous intravenous high-dose prostaglandin E(1). Ann Surg. 2007;246:229\u2013235.","journal-title":"Ann Surg"},{"key":"5835_CR37","doi-asserted-by":"publisher","first-page":"2117","DOI":"10.1007\/s11605-018-3855-1","volume":"22","author":"I Karampinis","year":"2018","unstructured":"Karampinis I, Keese M, Jakob J, et al. Indocyanine green tissue angiography can reduce extended bowel resections in acute mesenteric ischemia. J Gastrointest Surg. 2018;22:2117\u20132124.","journal-title":"J Gastrointest Surg"},{"key":"5835_CR38","doi-asserted-by":"publisher","first-page":"1254","DOI":"10.1053\/j.gastro.2011.06.073","volume":"141","author":"HC van Santvoort","year":"2011","unstructured":"van Santvoort HC, Bakker OJ, Bollen TL, et al. A conservative and minimally invasive approach to necrotizing pancreatitis improves outcome. Gastroenterology. 2011;141:1254\u20131263.","journal-title":"Gastroenterology"},{"key":"5835_CR39","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1136\/gutjnl-2012-302779","volume":"62","author":"PA Banks","year":"2013","unstructured":"Banks PA, Bollen TL, Dervenis C, et al. Classification of acute pancreatitis\u20142012: revision of the Atlanta classification and definitions by international consensus. Gut. 2013;62:102\u2013111.","journal-title":"Gut"}],"container-title":["Digestive Diseases and Sciences"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-019-05835-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10620-019-05835-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-019-05835-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,14]],"date-time":"2020-09-14T23:24:06Z","timestamp":1600125846000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10620-019-05835-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9,16]]},"references-count":39,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,4]]}},"alternative-id":["5835"],"URL":"https:\/\/doi.org\/10.1007\/s10620-019-05835-9","relation":{},"ISSN":["0163-2116","1573-2568"],"issn-type":[{"value":"0163-2116","type":"print"},{"value":"1573-2568","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,9,16]]},"assertion":[{"value":"25 July 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 September 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 September 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}