{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T07:16:22Z","timestamp":1740122182154,"version":"3.37.3"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2019,10,16]],"date-time":"2019-10-16T00:00:00Z","timestamp":1571184000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,10,16]],"date-time":"2019-10-16T00:00:00Z","timestamp":1571184000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Dig Dis Sci"],"published-print":{"date-parts":[[2020,6]]},"DOI":"10.1007\/s10620-019-05895-x","type":"journal-article","created":{"date-parts":[[2019,10,16]],"date-time":"2019-10-16T18:45:58Z","timestamp":1571251558000},"page":"1661-1668","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Reduction in Hospitalizations for Esophageal Reflux in a Decade with Minimal Increases in Other Functional and Motor Disorders"],"prefix":"10.1007","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3212-2400","authenticated-orcid":false,"given":"Thomas A.","family":"Zikos","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven","family":"Hendler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John O.","family":"Clarke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Triadafilopoulos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Berkeley N.","family":"Limketkai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,10,16]]},"reference":[{"key":"5895_CR1","doi-asserted-by":"publisher","first-page":"871","DOI":"10.1136\/gutjnl-2012-304269","volume":"63","author":"HB El-Serag","year":"2014","unstructured":"El-Serag HB, Sweet S, Winchester CC, Dent J. Update on the epidemiology of gastro-oesophageal reflux disease: a systematic review. Gut. 2014;63:871\u2013880.","journal-title":"Gut"},{"key":"5895_CR2","doi-asserted-by":"publisher","first-page":"1049","DOI":"10.1136\/gutjnl-2014-307843","volume":"64","author":"AC Ford","year":"2015","unstructured":"Ford AC, Marwaha A, Sood R, Moayyedi P. Global prevalence of, and risk factors for, uninvestigated dyspepsia: a meta-analysis. Gut. 2015;64:1049\u20131057.","journal-title":"Gut"},{"key":"5895_CR3","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1111\/j.1365-2036.2005.02396.x","volume":"21","author":"JY Kang","year":"2005","unstructured":"Kang JY. Systematic review: the influence of geography and ethnicity in irritable bowel syndrome. Aliment Pharmacol Ther. 2005;21:663\u2013676.","journal-title":"Aliment Pharmacol Ther"},{"key":"5895_CR4","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1053\/j.gastro.2012.10.028","volume":"144","author":"AE Bharucha","year":"2013","unstructured":"Bharucha AE, Pemberton JH, Locke GR 3rd. American Gastroenterological Association technical review on constipation. Gastroenterology. 2013;144:218\u2013238.","journal-title":"Gastroenterology"},{"key":"5895_CR5","doi-asserted-by":"publisher","first-page":"1225","DOI":"10.1053\/j.gastro.2008.12.047","volume":"136","author":"HK Jung","year":"2009","unstructured":"Jung HK, Choung RS, Locke GR 3rd, et al. The incidence, prevalence, and outcomes of patients with gastroparesis in Olmsted County, Minnesota, from 1996 to 2006. Gastroenterology. 2009;136:1225\u20131233.","journal-title":"Gastroenterology"},{"key":"5895_CR6","doi-asserted-by":"publisher","first-page":"1841","DOI":"10.1001\/jama.2015.2996","volume":"313","author":"JE Pandolfino","year":"2015","unstructured":"Pandolfino JE, Gawron AJ. Achalasia: a systematic review. JAMA. 2015;313:1841\u20131852.","journal-title":"JAMA"},{"key":"5895_CR7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.gtc.2013.11.006","volume":"43","author":"JH Rubenstein","year":"2014","unstructured":"Rubenstein JH, Chen JW. Epidemiology of gastroesophageal reflux disease. Gastroenterol Clin N Am. 2014;43:1\u201314.","journal-title":"Gastroenterol Clin N Am"},{"key":"5895_CR8","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/j.giec.2018.08.003","volume":"29","author":"P Loganathan","year":"2019","unstructured":"Loganathan P, Gajendran M, McCallum RW. Clinical manifestation and natural history of gastroparesis. Gastrointest Endosc Clin N Am. 2019;29:27\u201338.","journal-title":"Gastrointest Endosc Clin N Am"},{"key":"5895_CR9","doi-asserted-by":"publisher","first-page":"4428","DOI":"10.3748\/wjg.v23.i24.4428","volume":"23","author":"V Wadhwa","year":"2017","unstructured":"Wadhwa V, Mehta D, Jobanputra Y, Lopez R, Thota PN, Sanaka MR. Healthcare utilization and costs associated with gastroparesis. World J Gastroenterol. 2017;23:4428\u20134436.","journal-title":"World J Gastroenterol"},{"key":"5895_CR10","doi-asserted-by":"publisher","first-page":"949","DOI":"10.1001\/jama.2015.0954","volume":"313","author":"WD Chey","year":"2015","unstructured":"Chey WD, Kurlander J, Eswaran S. Irritable bowel syndrome: a clinical review. JAMA. 2015;313:949\u2013958.","journal-title":"JAMA"},{"key":"5895_CR11","doi-asserted-by":"publisher","first-page":"1853","DOI":"10.1056\/NEJMra1501505","volume":"373","author":"NJ Talley","year":"2015","unstructured":"Talley NJ, Ford AC. Functional dyspepsia. N Engl J Med. 2015;373:1853\u20131863.","journal-title":"N Engl J Med"},{"key":"5895_CR12","doi-asserted-by":"publisher","first-page":"684","DOI":"10.1111\/nmo.12542","volume":"27","author":"R Park","year":"2015","unstructured":"Park R, Mikami S, LeClair J, et al. Inpatient burden of childhood functional GI disorders in the USA: an analysis of national trends in the USA from 1997 to 2009. Neurogastroenterol Motil. 2015;27:684\u2013692.","journal-title":"Neurogastroenterol Motil"},{"key":"5895_CR13","doi-asserted-by":"publisher","first-page":"1680","DOI":"10.1007\/s10620-009-0863-8","volume":"54","author":"A Sonnenberg","year":"2009","unstructured":"Sonnenberg A. Hospitalization for achalasia in the United States 1997\u20132006. Dig Dis Sci. 2009;54:1680\u20131685. \nhttps:\/\/doi.org\/10.1007\/s10620-009-0863-8\n\n.","journal-title":"Dig Dis Sci"},{"key":"5895_CR14","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1038\/ajg.2013.423","volume":"109","author":"S Sethi","year":"2014","unstructured":"Sethi S, Mikami S, Leclair J, et al. Inpatient burden of constipation in the United States: an analysis of national trends in the United States from 1997 to 2010. Am J Gastroenterol. 2014;109:250\u2013256.","journal-title":"Am J Gastroenterol"},{"issue":"1731\u20131741","key":"5895_CR15","first-page":"e1733","volume":"149","author":"AF Peery","year":"2015","unstructured":"Peery AF, Crockett SD, Barritt AS, et al. Burden of gastrointestinal, liver, and pancreatic diseases in the United States. Gastroenterology. 2015;149:e1733.","journal-title":"Gastroenterology"},{"key":"5895_CR16","unstructured":"National Inpatient Sample Overview. Healthcare Cost and Utilization Project. \nhttps:\/\/www.hcup-us.ahrq.gov\/nisoverview.jsp\n\n. Accessed 16 Nov 2018."},{"key":"5895_CR17","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1111\/j.1365-2982.2012.02002.x","volume":"25","author":"S Nusrat","year":"2013","unstructured":"Nusrat S, Bielefeldt K. Gastroparesis on the rise: incidence vs awareness? Neurogastroenterol Motil. 2013;25:16\u201322.","journal-title":"Neurogastroenterol Motil"},{"key":"5895_CR18","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1002\/jcph.825","volume":"57","author":"DW Chang","year":"2017","unstructured":"Chang DW, Grotts J, Tseng CH, Brass EP. Time trends in physician visits for gastroesophageal reflux disease before and after the Rx-to-OTC switch of proton pump inhibitors. J Clin Pharmacol. 2017;57:452\u2013458.","journal-title":"J Clin Pharmacol"},{"key":"5895_CR19","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1016\/j.bone.2018.08.019","volume":"120","author":"MK Skjodt","year":"2018","unstructured":"Skjodt MK, Ostadahmadli Y, Abrahamsen B. Long term time trends in use of medications associated with risk of developing osteoporosis: Nationwide data for Denmark from 1999 to 2016. Bone. 2018;120:94\u2013100.","journal-title":"Bone"},{"key":"5895_CR20","doi-asserted-by":"publisher","first-page":"618","DOI":"10.1016\/j.ajem.2014.03.019","volume":"32","author":"M Mazer-Amirshahi","year":"2014","unstructured":"Mazer-Amirshahi M, Mullins PM, van den Anker J, Meltzer A, Pines JM. Rising rates of proton pump inhibitor prescribing in US emergency departments. Am J Emerg Med. 2014;32:618\u2013622.","journal-title":"Am J Emerg Med"},{"key":"5895_CR21","doi-asserted-by":"publisher","first-page":"e0208461","DOI":"10.1371\/journal.pone.0208461","volume":"13","author":"H Bustillos","year":"2018","unstructured":"Bustillos H, Leer K, Kitten A, Reveles KR. A cross-sectional study of national outpatient gastric acid suppressant prescribing in the United States between 2009 and 2015. PLoS ONE. 2018;13:e0208461.","journal-title":"PLoS ONE"},{"key":"5895_CR22","doi-asserted-by":"publisher","first-page":"1329","DOI":"10.1053\/j.gastro.2004.08.026","volume":"127","author":"P Moayyedi","year":"2004","unstructured":"Moayyedi P, Delaney BC, Vakil N, Forman D, Talley NJ. The efficacy of proton pump inhibitors in nonulcer dyspepsia: a systematic review and economic analysis. Gastroenterology. 2004;127:1329\u20131337.","journal-title":"Gastroenterology"},{"key":"5895_CR23","doi-asserted-by":"publisher","first-page":"697","DOI":"10.15585\/mmwr.mm6626a4","volume":"66","author":"GP Guy Jr","year":"2017","unstructured":"Guy GP Jr, Zhang K, Bohm MK, et al. Vital signs: changes in opioid prescribing in the United States, 2006\u20132015. MMWR Morb Mortal Wkly Rep. 2017;66:697\u2013704.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"5895_CR24","doi-asserted-by":"publisher","first-page":"1202","DOI":"10.1111\/nmo.12611","volume":"27","author":"TV Herregods","year":"2015","unstructured":"Herregods TV, Bredenoord AJ, Smout AJ. Pathophysiology of gastroesophageal reflux disease: new understanding in a new era. Neurogastroenterol Motil. 2015;27:1202\u20131213.","journal-title":"Neurogastroenterol Motil"},{"key":"5895_CR25","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1038\/ajg.2015.376","volume":"111","author":"C Hachem","year":"2016","unstructured":"Hachem C, Shaheen NJ. Diagnosis and management of functional heartburn. Am J Gastroenterol. 2016;111:53\u201361.","journal-title":"Am J Gastroenterol"}],"container-title":["Digestive Diseases and Sciences"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-019-05895-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10620-019-05895-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-019-05895-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,14]],"date-time":"2020-10-14T23:36:49Z","timestamp":1602718609000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10620-019-05895-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,16]]},"references-count":25,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2020,6]]}},"alternative-id":["5895"],"URL":"https:\/\/doi.org\/10.1007\/s10620-019-05895-x","relation":{},"ISSN":["0163-2116","1573-2568"],"issn-type":[{"type":"print","value":"0163-2116"},{"type":"electronic","value":"1573-2568"}],"subject":[],"published":{"date-parts":[[2019,10,16]]},"assertion":[{"value":"17 July 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 October 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 October 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"The authors declare no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}