{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T07:17:00Z","timestamp":1740122220990,"version":"3.37.3"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2020,6,3]],"date-time":"2020-06-03T00:00:00Z","timestamp":1591142400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,6,3]],"date-time":"2020-06-03T00:00:00Z","timestamp":1591142400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Dig Dis Sci"],"published-print":{"date-parts":[[2021,5]]},"DOI":"10.1007\/s10620-020-06357-5","type":"journal-article","created":{"date-parts":[[2020,6,3]],"date-time":"2020-06-03T15:07:54Z","timestamp":1591196874000},"page":"1588-1592","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The Meaning of Incidental Goblet Cells at the Gastroesophageal Junction"],"prefix":"10.1007","volume":"66","author":[{"given":"Kevin O.","family":"Turner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert M.","family":"Genta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5986-7042","authenticated-orcid":false,"given":"Amnon","family":"Sonnenberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,6,3]]},"reference":[{"key":"6357_CR1","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1053\/j.gastro.2019.12.003","volume":"158","author":"S Gupta","year":"2020","unstructured":"Gupta S, Li D, El Serag HB, et al. AGA clinical practice guidelines on management of gastric intestinal metaplasia. Gastroenterology. 2020;158:693\u2013702.","journal-title":"Gastroenterology"},{"key":"6357_CR2","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1038\/ajg.2015.322","volume":"111","author":"NJ Shaheen","year":"2016","unstructured":"Shaheen NJ, Falk GW, Iyer PG, Gerson LB, American College of Gastroenterology. ACG clinical guideline: diagnosis and management of Barrett\u2019s esophagus. Am J Gastroenterol. 2016;111:30\u201350.","journal-title":"Am J Gastroenterol"},{"key":"6357_CR3","doi-asserted-by":"publisher","first-page":"2052","DOI":"10.1007\/s10620-018-5063-y","volume":"63","author":"SJ Spechler","year":"2018","unstructured":"Spechler SJ. Cardiac metaplasia: follow, treat, or ignore? Dig Dis Sci. 2018;63:2052\u20132058.","journal-title":"Dig Dis Sci"},{"key":"6357_CR4","doi-asserted-by":"publisher","first-page":"915","DOI":"10.1016\/0046-8177(94)90011-6","volume":"25","author":"RM Genta","year":"1994","unstructured":"Genta RM, Huberman RM, Graham DY. The gastric cardia in Helicobacter pylori infection. Hum Pathol. 1994;25:915\u2013919.","journal-title":"Hum Pathol"},{"key":"6357_CR5","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1016\/S0016-5085(98)70576-1","volume":"114","author":"JR Goldblum","year":"1998","unstructured":"Goldblum JR, Vicari JJ, Falk GW, et al. Inflammation and intestinal metaplasia of the gastric cardia: the role of gastroesophageal reflux and H. pylori infection. Gastroenterology. 1998;114:633\u2013639.","journal-title":"Gastroenterology"},{"key":"6357_CR6","doi-asserted-by":"publisher","first-page":"522","DOI":"10.1097\/00000658-199710000-00013","volume":"226","author":"S Oberg","year":"1997","unstructured":"Oberg S, Peters JH, DeMeester TR, et al. Inflammation and specialized intestinal metaplasia of cardiac mucosa is a manifestation of gastroesophageal reflux disease. Ann Surg. 1997;226:522\u2013530.","journal-title":"Ann Surg"},{"key":"6357_CR7","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1097\/MOG.0000000000000273","volume":"32","author":"KE McColl","year":"2016","unstructured":"McColl KE, Derakhshan MH, Mitchell DR. Short-segment and intrasphincteric gastroesophageal reflux. Curr Opin Gastroenterol. 2016;32:332\u2013337.","journal-title":"Curr Opin Gastroenterol"},{"key":"6357_CR8","doi-asserted-by":"publisher","first-page":"1894","DOI":"10.1053\/j.gastro.2010.08.018","volume":"139","author":"A Sonnenberg","year":"2010","unstructured":"Sonnenberg A, Lash RH, Genta RM. A national study of H. pylori infection in gastric biopsy specimens. Gastroenterology. 2010;139:1894\u20131901.","journal-title":"Gastroenterology"},{"key":"6357_CR9","doi-asserted-by":"publisher","first-page":"2288","DOI":"10.1002\/ibd.22932","volume":"18","author":"A Sonnenberg","year":"2012","unstructured":"Sonnenberg A, Genta RM. Geographic distributions of microscopic colitis and inflammatory bowel disease in the United States. Inflamm Bowel Dis. 2012;18:2288\u20132293.","journal-title":"Inflamm Bowel Dis"},{"key":"6357_CR10","doi-asserted-by":"publisher","first-page":"1721","DOI":"10.1093\/aje\/kwt234","volume":"178","author":"B Lebwohl","year":"2013","unstructured":"Lebwohl B, Blaser MJ, Ludvigsson JF, et al. Decreased risk of celiac disease in patients with Helicobacter pylori colonization. Am J Epidemiol. 2013;178:1721\u20131730.","journal-title":"Am J Epidemiol"},{"key":"6357_CR11","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1111\/apt.13273","volume":"42","author":"ET Jensen","year":"2015","unstructured":"Jensen ET, Shah ND, Hoffman K, Sonnenberg A, Genta RM, Dellon ES. Seasonal variation in detection of esophageal eosinophilia and eosinophilic esophagitis. Aliment Pharmacol Ther. 2015;42:461\u2013469.","journal-title":"Aliment Pharmacol Ther"},{"key":"6357_CR12","doi-asserted-by":"publisher","first-page":"1056","DOI":"10.1038\/ajg.2015.130","volume":"110","author":"A Sonnenberg","year":"2015","unstructured":"Sonnenberg A, Genta RM. Low prevalence of colon polyps in chronic inflammatory conditions of the colon. Am J Gastroenterol. 2015;110:1056\u20131061.","journal-title":"Am J Gastroenterol"},{"key":"6357_CR13","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1038\/ajg.2017.439","volume":"113","author":"KO Turner","year":"2018","unstructured":"Turner KO, Genta RM, Sonnenberg A. Lesions of all types exist in colon polyps of all sizes. Am J Gastroenterol. 2018;113:303\u2013306.","journal-title":"Am J Gastroenterol"},{"key":"6357_CR14","doi-asserted-by":"publisher","first-page":"1733","DOI":"10.1097\/PAS.0b013e318078ce91","volume":"31","author":"A Srivastava","year":"2007","unstructured":"Srivastava A, Odze RD, Lauwers GY, Redston M, Antonioli DA, Glickman JN. Morphologic features are useful in distinguishing Barrett esophagus from carditis with intestinal metaplasia. Am J Surg Pathol. 2007;31:1733\u20131741.","journal-title":"Am J Surg Pathol"},{"key":"6357_CR15","doi-asserted-by":"publisher","first-page":"1161","DOI":"10.1097\/00000478-199610000-00001","volume":"120","author":"MF Dixon","year":"1996","unstructured":"Dixon MF, Genta RM, Yardley JH, Correa P. Classification and grading of gastritis: the updated Sydney system. Am J Surg Pathol. 1996;120:1161\u20131181.","journal-title":"Am J Surg Pathol"},{"key":"6357_CR16","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1053\/j.semdp.2006.04.001","volume":"22","author":"RM Genta","year":"2005","unstructured":"Genta RM. Differential diagnosis of reactive gastropathy. Semin Diagn Pathol. 2005;22:273\u2013283.","journal-title":"Semin Diagn Pathol"},{"key":"6357_CR17","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1111\/j.1572-0241.1999.00778.x","volume":"92","author":"JP Byrne","year":"1999","unstructured":"Byrne JP, Bhatnagar S, Hamid B, Armstrong GR, Attwood SE. Comparative study of intestinal metaplasia and mucin staining at the cardia and esophagogastric junction in 225 symptomatic patients presenting for diagnostic open-access gastroscopy. Am J Gastroenterol. 1999;92:98\u2013103.","journal-title":"Am J Gastroenterol"},{"key":"6357_CR18","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1016\/S1590-8658(01)80084-0","volume":"33","author":"G Zaninotto","year":"2001","unstructured":"Zaninotto G, Avellini C, Barbazza R, et al. Prevalence of intestinal metaplasia in the distal oesophagus, oesophagogastric junction and gastric cardia in symptomatic patients in north-east Italy: a prospective, descriptive survey. The Italian Ulcer Study Group \u201cGISU\u201d. Dig Liver Dis. 2001;33:316\u2013321.","journal-title":"Dig Liver Dis"},{"key":"6357_CR19","doi-asserted-by":"publisher","first-page":"e8","DOI":"10.1097\/PAS.0000000000000819","volume":"41","author":"A Srivastava","year":"2017","unstructured":"Srivastava A, Appelman H, Goldsmith JD, Davison JM, Hart J, Krasinskas AM. The use of ancillary stains in the diagnosis of Barrett esophagus and Barrett esophagus\u2014associated dysplasia: recommendations from the Rodger C. Haggitt Gastrointestinal Pathology Society. Am J Surg Pathol. 2017;41:e8\u2013e21.","journal-title":"Am J Surg Pathol"},{"key":"6357_CR20","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1016\/j.dld.2017.12.034","volume":"50","author":"RM Genta","year":"2018","unstructured":"Genta RM, Turner KO, Lash RH. Upfront Alcian Blue-periodic acid Schiff stain for the assessment of upper gastrointestinal disorders. Dig Liver Dis. 2018;50:417\u2013418.","journal-title":"Dig Liver Dis"},{"key":"6357_CR21","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1136\/gut.50.3.368","volume":"50","author":"HB El-Serag","year":"2002","unstructured":"El-Serag HB, Mason AC, Petersen N, Key CR. Epidemiological differences between adenocarcinoma of the oesophagus and adenocarcinoma of the gastric cardia in the USA. Gut. 2002;50:368\u2013372.","journal-title":"Gut"},{"key":"6357_CR22","doi-asserted-by":"publisher","first-page":"e12504","DOI":"10.1111\/hel.12504","volume":"23","author":"B Er\u0151ss","year":"2018","unstructured":"Er\u0151ss B, Farkas N, Vincze \u00c1, et al. Helicobacter pylori infection reduces the risk of Barrett\u2019s esophagus: a meta-analysis and systematic review. Helicobacter. 2018;23:e12504.","journal-title":"Helicobacter"},{"key":"6357_CR23","doi-asserted-by":"publisher","first-page":"1545","DOI":"10.1136\/gutjnl-2018-318126","volume":"68","author":"M Banks","year":"2019","unstructured":"Banks M, Graham D, Jansen M, et al. British Society of Gastroenterology guidelines on the diagnosis and management of patients at risk of gastric adenocarcinoma. Gut. 2019;68:1545\u20131575.","journal-title":"Gut"},{"key":"6357_CR24","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1016\/S0016-5107(04)00179-8","volume":"59","author":"GC Harewood","year":"2004","unstructured":"Harewood GC, Holub JL, Lieberman DA. Biopsy specimen acquisition in patients with newly diagnosed peptic ulcer disease as determined from a national endoscopic database. Gastrointest Endosc. 2004;59:664\u2013669.","journal-title":"Gastrointest Endosc"}],"container-title":["Digestive Diseases and Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-020-06357-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10620-020-06357-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-020-06357-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,3]],"date-time":"2021-06-03T01:35:52Z","timestamp":1622684152000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10620-020-06357-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,3]]},"references-count":24,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021,5]]}},"alternative-id":["6357"],"URL":"https:\/\/doi.org\/10.1007\/s10620-020-06357-5","relation":{},"ISSN":["0163-2116","1573-2568"],"issn-type":[{"type":"print","value":"0163-2116"},{"type":"electronic","value":"1573-2568"}],"subject":[],"published":{"date-parts":[[2020,6,3]]},"assertion":[{"value":"8 February 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 May 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 June 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"Kevin O. Turner and Robert M. Genta are employed by Inform Diagnostics, Irving, TX. Amnon Sonnenberg has no conflict of interest to declare.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}