{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T14:29:19Z","timestamp":1782570559801,"version":"3.54.5"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2021,1,19]],"date-time":"2021-01-19T00:00:00Z","timestamp":1611014400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,1,19]],"date-time":"2021-01-19T00:00:00Z","timestamp":1611014400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Dig Dis Sci"],"published-print":{"date-parts":[[2021,12]]},"DOI":"10.1007\/s10620-020-06815-0","type":"journal-article","created":{"date-parts":[[2021,1,19]],"date-time":"2021-01-19T19:03:01Z","timestamp":1611082981000},"page":"4467-4474","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Analysis of Risk Factors in Endoscopic Retrograde Cholangiopancreatography-Related Immediate and Delayed Hemorrhage"],"prefix":"10.1007","volume":"66","author":[{"given":"Xiaoling","family":"Ye","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyue","family":"Wan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0126-190X","authenticated-orcid":false,"given":"Tao","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,1,19]]},"reference":[{"key":"6815_CR1","doi-asserted-by":"publisher","first-page":"3302","DOI":"10.1007\/s10620-016-4283-2","volume":"61","author":"M Ukkonen","year":"2016","unstructured":"Ukkonen M, Siiki A, Antila A, et al. Safety and efficacy of acute endoscopic retrograde cholangiopancreatography in the elderly. Dig Dis Sci. 2016;61:3302\u20133308. https:\/\/doi.org\/10.1007\/s10620-016-4283-2.","journal-title":"Dig Dis Sci."},{"key":"6815_CR2","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1007\/s40520-015-0453-x","volume":"28","author":"Y Lu","year":"2016","unstructured":"Lu Y, Chen L, Jin Z, Bie LK, Gong B. Is ERCP both effective and safe for common bile duct stones removal in octogenarians? A comparative study. Aging Clin Exp Res. 2016;28:647\u2013652","journal-title":"Aging Clin Exp Res."},{"key":"6815_CR3","doi-asserted-by":"publisher","first-page":"1965","DOI":"10.1007\/s00464-007-9711-0","volume":"22","author":"P Salminen","year":"2008","unstructured":"Salminen P, Lainn S, Gullichsen R. Severe and fatal complications after ERCP: analysis of 2555 procedures in a single experienced center. Surg Endosc. 2008;22:1965\u20131970","journal-title":"Surg Endosc."},{"key":"6815_CR4","first-page":"1","volume":"2018","author":"F Afridi","year":"2019","unstructured":"Afridi F, Rotundo L, Feurdean M, Ahlawat S. Trends in post-therapeutic endoscopic retrograde cholangiopancreatography gastrointestinal hemorrhage, perforation and mortality from 2000 to 2012: a nationwide study. Digestion. 2019;2018:1\u20139","journal-title":"Digestion."},{"key":"6815_CR5","doi-asserted-by":"publisher","first-page":"793","DOI":"10.1016\/j.bpg.2016.10.007","volume":"30","author":"R Talukdar","year":"2016","unstructured":"Talukdar R. Complications of ERCP. Best Pract Res Clin Gastroenterol. 2016;30:793\u2013805","journal-title":"Best Pract Res Clin Gastroenterol."},{"key":"6815_CR6","doi-asserted-by":"publisher","first-page":"305","DOI":"10.5946\/ce.2012.45.3.305","volume":"45","author":"M Kahaleh","year":"2012","unstructured":"Kahaleh M, Freeman M. Prevention and management of post-endoscopic retrograde cholangiopancreatography complications. Clin Endosc. 2012;45:305\u2013312","journal-title":"Clin Endosc."},{"key":"6815_CR7","doi-asserted-by":"publisher","first-page":"2850","DOI":"10.1111\/j.1572-0241.2007.01563.x","volume":"102","author":"LEVVC Ferreira","year":"2007","unstructured":"Ferreira LEVVC, Baron TH. Post-sphincterotomy bleeding: who, what, when, and how. Am J Gastroenterol. 2007;102:2850\u20132858","journal-title":"Am J Gastroenterol."},{"key":"6815_CR8","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1055\/a-1075-4080","volume":"52","author":"JM Dumonceau","year":"2020","unstructured":"Dumonceau JM, Kapral C, Aabakken L, et al. ERCP-related adverse events: European Society of Gastrointestinal Endoscopy (ESGE) guideline. Endoscopy. 2020;52:127\u2013149","journal-title":"Endoscopy."},{"key":"6815_CR9","doi-asserted-by":"publisher","first-page":"446","DOI":"10.1016\/j.gie.2009.10.027","volume":"71","author":"PB Cotton","year":"2010","unstructured":"Cotton PB, Eisen GM, Aabakken L, et al. A lexicon for endoscopic adverse events: report of an ASGE workshop. Gastrointest Endosc. 2010;71:446\u2013454","journal-title":"Gastrointest Endosc."},{"key":"6815_CR10","first-page":"65","volume":"27","author":"P Katsinelos","year":"2014","unstructured":"Katsinelos P, Lazaraki G, Chatzimavroudis G, et al. Risk factors for therapeutic ERCP-related complications: an analysis of 2715 cases performed by a single endoscopist. Ann Gastroenterol. 2014;27:65\u201372","journal-title":"Ann Gastroenterol."},{"key":"6815_CR11","doi-asserted-by":"publisher","first-page":"1364","DOI":"10.1007\/s10620-018-5314-y","volume":"64","author":"M Jayaraj","year":"2019","unstructured":"Jayaraj M, Mohan BP, Dhindsa BS, et al. Periampullary diverticula and ERCP outcomes: a systematic review and meta-analysis. Dig Dis Sci. 2019;64:1364\u20131376. https:\/\/doi.org\/10.1007\/s10620-018-5314-y.","journal-title":"Dig Dis Sci."},{"key":"6815_CR12","first-page":"496","volume":"9","author":"NM Szary","year":"2013","unstructured":"Szary NM, Al-Kawas FH. Complications of endoscopic retrograde cholangiopancreatography: how to avoid and manage them. Gastroenterol Hepatol (N Y). 2013;9:496\u2013504","journal-title":"Gastroenterol Hepatol (N Y)."},{"key":"6815_CR13","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1053\/ge.2003.v57.amge030576633","volume":"57","author":"JS Mallery","year":"2003","unstructured":"Mallery JS, Baron TH, Dominitz JA, et al. Complications of ERCP. Gastrointest Endosc. 2003;57:633\u2013638","journal-title":"Gastrointest Endosc."},{"key":"6815_CR14","doi-asserted-by":"publisher","first-page":"106","DOI":"10.4103\/sjg.SJG_246_18","volume":"25","author":"MC Tsai","year":"2019","unstructured":"Tsai MC, Wang CC, Wang YT, et al. Major bleeding risk of endoscopic sphincterotomy versus endoscopic papillary balloon dilatation in hemodialysis patients. Saudi J Gastroenterol. 2019;25:106\u2013112","journal-title":"Saudi J Gastroenterol."},{"key":"6815_CR15","doi-asserted-by":"publisher","first-page":"3141","DOI":"10.1007\/s10620-018-5112-6","volume":"63","author":"SB Kim","year":"2018","unstructured":"Kim SB, Kim KH, Kim TN. Safety and efficacy of endoscopic retrograde cholangiopancreatography for choledocholithiasis in long-term dialysis: a propensity score analysis. Dig Dis Sci. 2018;63:3141\u20133146. https:\/\/doi.org\/10.1007\/s10620-018-5112-6.","journal-title":"Dig Dis Sci."},{"key":"6815_CR16","doi-asserted-by":"publisher","first-page":"1457","DOI":"10.1111\/liv.13100","volume":"36","author":"S Inamdar","year":"2016","unstructured":"Inamdar S, Berzin TM, Berkowitz J, et al. Decompensated cirrhosis may be a risk factor for adverse events in endoscopic retrograde cholangiopancreatography. Liver Int. 2016;36:1457\u20131463","journal-title":"Liver Int."},{"key":"6815_CR17","doi-asserted-by":"publisher","first-page":"354","DOI":"10.4253\/wjge.v10.i11.354","volume":"10","author":"HS Mashiana","year":"2018","unstructured":"Mashiana HS, Dhaliwal AS, Sayles H, et al. Endoscopic retrograde cholangiopancreatography in cirrhosis\u2014a systematic review and meta-analysis focused on adverse events. World J Gastro Endosc. 2018;10:354\u2013366","journal-title":"World J Gastro Endosc."},{"key":"6815_CR18","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1038\/s41395-018-0218-1","volume":"114","author":"C Leal","year":"2019","unstructured":"Leal C, Prado V, Colan J, et al. Adverse events and acute chronic liver failure in patients with cirrhosis undergoing endoscopic retrograde cholangiopancreatography: a multicenter matched-cohort Study. Am J Gastroenterol. 2019;114:89\u201397","journal-title":"Am J Gastroenterol."},{"key":"6815_CR19","doi-asserted-by":"publisher","first-page":"E303","DOI":"10.1055\/s-0043-102492","volume":"5","author":"U Navaneethan","year":"2017","unstructured":"Navaneethan U, Njei B, Zhu X, et al. Safety of ERCP in patients with liver cirrhosis: a national database study. Endosc Int Open. 2017;5:E303\u2013E314","journal-title":"Endosc Int Open."},{"key":"6815_CR20","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1016\/j.gie.2015.08.022","volume":"83","author":"DG Adler","year":"2016","unstructured":"Adler DG, Haseeb A, Francis G, et al. Efficacy and safety of therapeutic ERCP in patients with cirrhosis: a large multicenter study. Gastrointest Endosc. 2016;83:353\u2013359","journal-title":"Gastrointest Endosc."},{"key":"6815_CR21","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1177\/1457496914529274","volume":"104","author":"RB Ambrus","year":"2015","unstructured":"Ambrus RB, Svendsen LB, Hillingso JG, Hansen ML, Achiam MP. Post-endoscopic retrograde cholangiopancreaticography complications in liver transplanted patients, a single-center experience. Scand J Surg. 2015;104:86\u201391","journal-title":"Scand J Surg."},{"key":"6815_CR22","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1016\/j.gie.2011.04.025","volume":"74","author":"D Balderramo","year":"2011","unstructured":"Balderramo D, Bordas JM, Sendino O, et al. Complications after ERCP in liver transplant recipients. Gastrointest Endosc. 2011;74:285\u2013294","journal-title":"Gastrointest Endosc."},{"key":"6815_CR23","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1016\/j.ajg.2015.04.001","volume":"16","author":"A Husing","year":"2015","unstructured":"Husing A, Cicinnati VR, Maschmeier M, et al. Complications after endoscopic sphincterotomy in liver transplant recipients: a retrospective single-centre study. Arab J Gastroenterol. 2015;16:46\u201349","journal-title":"Arab J Gastroenterol."},{"key":"6815_CR24","doi-asserted-by":"publisher","first-page":"1319","DOI":"10.1016\/j.transproceed.2009.03.086","volume":"41","author":"C Sanna","year":"2009","unstructured":"Sanna C, Saracco GM, Reggio D, et al. Endoscopic retrograde cholangiopancreatography in patients with biliary complications after orthotopic liver transplantation: outcomes and complications. Transplant Proc. 2009;41:1319\u20131321","journal-title":"Transplant Proc."},{"key":"6815_CR25","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1002\/bjs.8992","volume":"100","author":"T Glomsaker","year":"2013","unstructured":"Glomsaker T, Hoff G, Kvaloy JT, et al. Patterns and predictive factors of complications after endoscopic retrograde cholangiopancreatography. Brit J Surg. 2013;100:373\u2013380","journal-title":"Brit J Surg."},{"key":"6815_CR26","doi-asserted-by":"publisher","first-page":"e16529","DOI":"10.1097\/MD.0000000000016529","volume":"98","author":"TH Hung","year":"2019","unstructured":"Hung TH, Tseng CW, Chen YC, et al. Endoscopic papillary balloon dilation decreases the risk of bleeding in cirrhotic patients compared with endoscopic biliary sphincterotomy: a national population-based study. Medicine (Baltimore). 2019;98:e16529","journal-title":"Medicine (Baltimore)."},{"key":"6815_CR27","doi-asserted-by":"publisher","first-page":"924","DOI":"10.1016\/j.gie.2014.09.015","volume":"81","author":"U Navaneethan","year":"2015","unstructured":"Navaneethan U, Konjeti R, Lourdusamy V, et al. Precut sphincterotomy: efficacy for ductal access and the risk of adverse events. Gastrointest Endosc. 2015;81:924\u2013931","journal-title":"Gastrointest Endosc."},{"key":"6815_CR28","first-page":"241","volume":"30","author":"JH Kim","year":"2015","unstructured":"Kim JH, Yang MJ, Hwang JC, Yoo BM. Usefulness of 4-h post-ERCP serum amylase and lipase levels for prediction of post-ERCP pancreatitis. J Gastroen Hepatol. 2015;30:241\u2013241","journal-title":"J Gastroen Hepatol."},{"key":"6815_CR29","doi-asserted-by":"publisher","first-page":"54","DOI":"10.4103\/jrms.JRMS_1100_17","volume":"23","author":"M Minakari","year":"2018","unstructured":"Minakari M, Sebghatollahi V, Sattari M, Fahami E. Serum amylase and lipase levels for prediction of postendoscopic retrograde cholangiopancreatography pancreatitis. J Res Med Sci. 2018;23:54","journal-title":"J Res Med Sci."}],"container-title":["Digestive Diseases and Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-020-06815-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10620-020-06815-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-020-06815-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,12]],"date-time":"2021-11-12T18:21:08Z","timestamp":1636741268000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10620-020-06815-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,19]]},"references-count":29,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["6815"],"URL":"https:\/\/doi.org\/10.1007\/s10620-020-06815-0","relation":{},"ISSN":["0163-2116","1573-2568"],"issn-type":[{"value":"0163-2116","type":"print"},{"value":"1573-2568","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1,19]]},"assertion":[{"value":"24 September 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 December 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 January 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"The authors declare that they have no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures performed in this study involving human participants were in accordance with the ethical standards of institutional research committee and with the 1964 Helsinki declaration and its later amendments. For this type of study, formal consent is not required.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}