{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T01:06:26Z","timestamp":1783645586033,"version":"3.55.0"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2021,11,5]],"date-time":"2021-11-05T00:00:00Z","timestamp":1636070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2021,11,5]],"date-time":"2021-11-05T00:00:00Z","timestamp":1636070400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Dig Dis Sci"],"published-print":{"date-parts":[[2022,7]]},"DOI":"10.1007\/s10620-021-07277-8","type":"journal-article","created":{"date-parts":[[2021,11,5]],"date-time":"2021-11-05T13:02:57Z","timestamp":1636117377000},"page":"3327-3332","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Validation of the New Diagnostic Criteria for Clinically Significant Portal Hypertension by Platelets and Elastography"],"prefix":"10.1007","volume":"67","author":[{"given":"Kristian","family":"Podrug","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vladimir","family":"Trkulja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marko","family":"Zelenika","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomislav","family":"Bokun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anita","family":"Madir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tajana Filipec","family":"Kanizaj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"O\u2019Beirne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0520-3483","authenticated-orcid":false,"given":"Ivica","family":"Grgurevic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,11,5]]},"reference":[{"key":"7277_CR1","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1053\/j.gastro.2007.05.024","volume":"133","author":"C Ripoll","year":"2007","unstructured":"Ripoll C, Groszmann R, Garcia-Tsao G et al. Portal Hypertension Collaborative Group. Hepatic venous pressure gradient predicts clinical decompensation in patients with compensated cirrhosis. Gastroenterology. 2007;133:481\u2013488.","journal-title":"Gastroenterology."},{"key":"7277_CR2","doi-asserted-by":"publisher","first-page":"1597","DOI":"10.1016\/S0140-6736(18)31875-0","volume":"393","author":"C Villanueva","year":"2019","unstructured":"Villanueva C, Albillos A, Genesc\u00e0 J et al. \u03b2 blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial. Lancet. 2019;393:1597\u20131608.","journal-title":"Lancet."},{"key":"7277_CR3","doi-asserted-by":"crossref","unstructured":"de Franchis R; Baveno V Faculty. Expanding consensus in portal hypertension. Report of the Baveno VI Consensus Workshop: stratifying risk and individualizing care for portal hypertension. J Hepatol. 2015;63:743\u2013752.","DOI":"10.1007\/978-3-319-23018-4"},{"key":"7277_CR4","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1038\/nrgastro.2009.149","volume":"6","author":"J Bosch","year":"2009","unstructured":"Bosch J, Abraldes JG, Berzigotti A, Garc\u00eda-Pagan JC. The clinical use of HVPG measurements in chronic liver disease. Nat Rev Gastroenterol Hepatol. 2009;6:573\u2013582.","journal-title":"Nat Rev Gastroenterol Hepatol."},{"key":"7277_CR5","doi-asserted-by":"publisher","unstructured":"Pons M, Augustin S, Scheiner B et al. Noninvasive diagnosis of portal hypertension in patients with compensated advanced chronic liver disease. Am J Gastroenterol. 2020. https:\/\/doi.org\/10.14309\/ajg.0000000000000994. Epub ahead of print. PMID: 33038131.","DOI":"10.14309\/ajg.0000000000000994"},{"key":"7277_CR6","doi-asserted-by":"publisher","first-page":"846","DOI":"10.1016\/j.jhep.2009.12.031","volume":"52","author":"A Berzigotti","year":"2010","unstructured":"Berzigotti A, Abraldes JG, Tandon P et al. Ultrasonographic evaluation of liver surface and transient elastography in clinically doubtful cirrhosis. J Hepatol. 2010;52:846\u2013853.","journal-title":"J Hepatol."},{"key":"7277_CR7","doi-asserted-by":"publisher","first-page":"100147","DOI":"10.1016\/j.jhepr.2020.100147","volume":"2","author":"A Souhami","year":"2020","unstructured":"Souhami A, Sartoris R, Rautou PE et al. Similar performance of liver stiffness measurement and liver surface nodularity for the detection of portal hypertension in patients with hepatocellular carcinoma. JHEP Rep. 2020;2:100147.","journal-title":"JHEP Rep."},{"key":"7277_CR8","first-page":"e16","volume":"38","author":"CF Dietrich","year":"2017","unstructured":"Dietrich CF, Bamber J, Berzigotti A et al. EFSUMB guidelines and recommendations on the clinical use of liver ultrasound elastography, update 2017 (long version). Ultraschall Med. 2017;38:e16\u2013e47.","journal-title":"Ultraschall Med."},{"key":"7277_CR9","doi-asserted-by":"publisher","first-page":"526","DOI":"10.1002\/hep.27431","volume":"61","author":"A Berzigotti","year":"2015","unstructured":"Berzigotti A, Reig M, Abraldes JG, Bosch J, Bruix J. Portal hypertension and the outcome of surgery for hepatocellular carcinoma in compensated cirrhosis: a systematic review and meta-analysis. Hepatology. 2015;61:526\u2013536.","journal-title":"Hepatology."},{"key":"7277_CR10","doi-asserted-by":"publisher","first-page":"942","DOI":"10.1016\/j.jhep.2019.07.007","volume":"71","author":"E Reverter","year":"2019","unstructured":"Reverter E, Cirera I, Albillos A et al. The prognostic role of hepatic venous pressure gradient in cirrhotic patients undergoing elective extrahepatic surgery. J Hepatol. 2019;71:942\u2013950.","journal-title":"J Hepatol."},{"key":"7277_CR11","doi-asserted-by":"publisher","first-page":"916","DOI":"10.14309\/ajg.0000000000000153","volume":"114","author":"S Petta","year":"2019","unstructured":"Petta S, Wai-Sun Wong V, Bugianesi E et al. Impact of obesity and alanine aminotransferase levels on the diagnostic accuracy for advanced liver fibrosis of noninvasive tools in patients with nonalcoholic fatty liver disease. Am J Gastroenterol. 2019;114:916\u2013928.","journal-title":"Am J Gastroenterol."},{"key":"7277_CR12","doi-asserted-by":"publisher","first-page":"2057","DOI":"10.1136\/gutjnl-2018-317334","volume":"68","author":"VW Wong","year":"2019","unstructured":"Wong VW, Irles M, Wong GL et al. Unified interpretation of liver stiffness measurement by M and XL probes in non-alcoholic fatty liver disease. Gut. 2019;68:2057\u20132064.","journal-title":"Gut."},{"key":"7277_CR13","doi-asserted-by":"publisher","first-page":"966","DOI":"10.3748\/wjg.v16.i8.966","volume":"16","author":"S Mueller","year":"2010","unstructured":"Mueller S, Millonig G, Sarovska L et al. Increased liver stiffness in alcoholic liver disease: differentiating fibrosis from steatohepatitis. World J Gastroenterol. 2010;16:966\u2013972.","journal-title":"World J Gastroenterol."},{"key":"7277_CR14","doi-asserted-by":"publisher","first-page":"1062","DOI":"10.1016\/j.jhep.2008.08.011","volume":"49","author":"P Nahon","year":"2008","unstructured":"Nahon P, Kettaneh A, Tengher-Barna I et al. Assessment of liver fibrosis using transient elastography in patients with alcoholic liver disease. J Hepatol. 2008;49:1062\u20131068.","journal-title":"J Hepatol."}],"container-title":["Digestive Diseases and Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-021-07277-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10620-021-07277-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-021-07277-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,8]],"date-time":"2025-04-08T11:29:17Z","timestamp":1744111757000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10620-021-07277-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,5]]},"references-count":14,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2022,7]]}},"alternative-id":["7277"],"URL":"https:\/\/doi.org\/10.1007\/s10620-021-07277-8","relation":{},"ISSN":["0163-2116","1573-2568"],"issn-type":[{"value":"0163-2116","type":"print"},{"value":"1573-2568","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,5]]},"assertion":[{"value":"9 June 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 August 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 November 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no conflict of interest. Each author has approved the final draft submitted.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}