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M.P. has received grant support from Bausch Health and Synthetic Biologics. R.M. has received grant support from Bausch Health. A.R. is a consultant\/speaker for and has received grant support from Bausch Health. Cedars-Sinai has a licensing agreement with Gemelli Biotech and Hobbs Medical. A.R., M.P., and R.M. have equity in Gemelli Biotech and GoodLFE. M. P. has equity in Cylinder Health and Salvo Health. The remaining authors report no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the Institutional Review Board and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. 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