{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:07:00Z","timestamp":1787065620502,"version":"build-2736575974"},"reference-count":13,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2025,11,29]],"date-time":"2025-11-29T00:00:00Z","timestamp":1764374400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,11,29]],"date-time":"2025-11-29T00:00:00Z","timestamp":1764374400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Dig Dis Sci"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1007\/s10620-025-09594-8","type":"journal-article","created":{"date-parts":[[2025,11,29]],"date-time":"2025-11-29T09:11:14Z","timestamp":1764407474000},"page":"1716-1721","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Prevalence of Precursor Lesions in Gastric Adenocarcinoma Specimen: Insights into Pathogenesis in the United States Population"],"prefix":"10.1007","volume":"71","author":[{"given":"Jameel","family":"Alp","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erica","family":"Loon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir Sultan","family":"Seid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalie","family":"Wilson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan C.","family":"Manivel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Hanson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rahul","family":"Karna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Bilal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,11,29]]},"reference":[{"key":"9594_CR1","doi-asserted-by":"publisher","first-page":"709","DOI":"10.14309\/ajg.0000000000003350","volume":"120","author":"DR Morgan","year":"2025","unstructured":"Morgan DR, Corral JE, Li D et al. ACG Clinical Guideline: Diagnosis and Management of Gastric Premalignant Conditions. Am J Gastroenterol. 2025;120:709\u2013737.","journal-title":"Am J Gastroenterol."},{"key":"9594_CR2","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/S0140-6736(75)90498-5","volume":"2","author":"P Correa","year":"1975","unstructured":"Correa P, Haenszel W, Cuello C et al. A model for gastric cancer epidemiology. Lancet. 1975;2:58\u201360.","journal-title":"Lancet."},{"key":"9594_CR3","doi-asserted-by":"publisher","first-page":"2113","DOI":"10.1136\/gutjnl-2020-320839","volume":"69","author":"AC Ford","year":"2020","unstructured":"Ford AC, Yuan Y, Moayyedi P. Helicobacter pylori eradication therapy to prevent gastric cancer: systematic review and meta-analysis. Gut. 2020;69:2113\u20132121.","journal-title":"Gut."},{"key":"9594_CR4","doi-asserted-by":"publisher","first-page":"25","DOI":"10.15430\/JCP.2015.20.1.25","volume":"20","author":"YH Park","year":"2015","unstructured":"Park YH, Kim N. Review of atrophic gastritis and intestinal metaplasia as a premalignant lesion of gastric cancer. J Cancer Prev. 2015;20:25\u201340.","journal-title":"J Cancer Prev."},{"key":"9594_CR5","doi-asserted-by":"publisher","first-page":"1104","DOI":"10.1038\/ajg.2016.188","volume":"111","author":"D Li","year":"2016","unstructured":"Li D, Bautista MC, Jiang SF et al. Risks and Predictors of Gastric Adenocarcinoma in Patients with Gastric Intestinal Metaplasia and Dysplasia: A Population-Based Study. Am J Gastroenterol. 2016;111:1104\u20131113.","journal-title":"Am J Gastroenterol."},{"key":"9594_CR6","doi-asserted-by":"publisher","first-page":"3922","DOI":"10.1111\/cas.15545","volume":"113","author":"N Narii","year":"2022","unstructured":"Narii N, Sobue T, Zha L et al. Effectiveness of endoscopic screening for gastric cancer: The Japan Public Health Center-based Prospective Study. Cancer Sci. 2022;113:3922\u20133931.","journal-title":"Cancer Sci."},{"key":"9594_CR7","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1007\/s00535-022-01878-4","volume":"57","author":"XQ Luu","year":"2022","unstructured":"Luu XQ, Lee K, Jun JK et al. Effect of gastric cancer screening on long-term survival of gastric cancer patients: results of Korean national cancer screening program. J Gastroenterol. 2022;57:464\u2013475.","journal-title":"J Gastroenterol."},{"key":"9594_CR8","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1016\/j.surg.2019.04.036","volume":"166","author":"JR Bergquist","year":"2019","unstructured":"Bergquist JR, Leiting JL, Habermann EB et al. Early-onset gastric cancer is a distinct disease with worrisome trends and oncogenic features. Surgery. 2019;166:547\u2013555.","journal-title":"Surgery."},{"key":"9594_CR9","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1136\/flgastro-2018-101089","volume":"12","author":"W Waddingham","year":"2021","unstructured":"Waddingham W, Nieuwenburg SAV, Carlson S et al. Recent advances in the detection and management of early gastric cancer and its precursors. Frontline Gastroenterol. 2021;12:322\u2013331.","journal-title":"Frontline Gastroenterol."},{"key":"9594_CR10","doi-asserted-by":"publisher","first-page":"227","DOI":"10.2174\/1871520611313020007","volume":"13","author":"L Liu","year":"2013","unstructured":"Liu L, Wang ZW, Ji J et al. A cohort study and meta-analysis between histopathological classification and prognosis of gastric carcinoma. Anticancer Agents Med Chem. 2013;13:227\u2013234.","journal-title":"Anticancer Agents Med Chem."},{"key":"9594_CR11","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1038\/s41575-022-00591-0","volume":"19","author":"Y Zavros","year":"2022","unstructured":"Zavros Y, Merchant JL. The immune microenvironment in gastric adenocarcinoma. Nat Rev Gastroenterol Hepatol. 2022;19:451\u2013467.","journal-title":"Nat Rev Gastroenterol Hepatol."},{"key":"9594_CR12","doi-asserted-by":"publisher","first-page":"1079","DOI":"10.1002\/jso.26874","volume":"125","author":"A Ivey","year":"2022","unstructured":"Ivey A, Pratt H, Boone BA. Molecular pathogenesis and emerging targets of gastric adenocarcinoma. J Surg Oncol. 2022;125:1079\u20131095.","journal-title":"J Surg Oncol."},{"key":"9594_CR13","doi-asserted-by":"publisher","first-page":"378","DOI":"10.1097\/MEG.0000000000000065","volume":"26","author":"L Marques-Silva","year":"2014","unstructured":"Marques-Silva L, Areia M, Elvas L, Dinis-Ribeiro M. Prevalence of gastric precancerous conditions: a systematic review and meta-analysis. Eur J Gastroenterol Hepatol. 2014;26:378\u2013387.","journal-title":"Eur J Gastroenterol Hepatol."}],"container-title":["Digestive Diseases and Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-025-09594-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10620-025-09594-8","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-025-09594-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T05:06:30Z","timestamp":1779685590000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10620-025-09594-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,29]]},"references-count":13,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["9594"],"URL":"https:\/\/doi.org\/10.1007\/s10620-025-09594-8","relation":{},"ISSN":["0163-2116","1573-2568"],"issn-type":[{"value":"0163-2116","type":"print"},{"value":"1573-2568","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,29]]},"assertion":[{"value":"1 August 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 November 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 November 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Jameel Alp, Erica Loon, Amir Sultan Seid, Natalie Wilson, Juan C Manivel, Brian Hanson, Rahul Karna declares no conflicts of interest. Mohammad Bilal is a consultant for Boston Scientific, Steris Endoscopy, and a paid speaker for Cook Endoscopy.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}