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Effective pain control remains challenging due to the multifactorial and complex etiology of pain, yet it is essential for improving patient outcomes.<\/jats:p>\n                  <jats:p>An accurate pain assessment using validated clinical tools is a critical first step toward optimizing management. Effective treatment often requires a multidisciplinary, multimodal approach that integrates lifestyle modifications, including smoking and alcohol cessation, with stepwise pharmacologic therapy. For patients with refractory pain, surgical and endoscopic interventions are viable treatment options.<\/jats:p>\n                  <jats:p>This review provides a comprehensive overview of non-pharmacologic, pharmacologic, endoscopic, and surgical strategies for managing painful chronic pancreatitis, emphasizing evidence-based approaches that improve patient outcomes.<\/jats:p>","DOI":"10.1007\/s10620-025-09626-3","type":"journal-article","created":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T06:14:47Z","timestamp":1766556887000},"page":"2525-2531","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Analgesic Management of Chronic Pancreatitis"],"prefix":"10.1007","volume":"71","author":[{"given":"Dominic","family":"Amakye","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hadie","family":"Razjouyan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew D.","family":"Coates","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,12,24]]},"reference":[{"key":"9626_CR1","doi-asserted-by":"publisher","first-page":"720","DOI":"10.1016\/j.pan.2017.07.006","volume":"17","author":"AM Drewes","year":"2017","unstructured":"Drewes AM, Bouwense SAW, Campbell CM et al. 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