{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T03:20:22Z","timestamp":1787541622910,"version":"build-2736575974"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T00:00:00Z","timestamp":1773705600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T00:00:00Z","timestamp":1773705600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Dig Dis Sci"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1007\/s10620-026-09838-1","type":"journal-article","created":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T19:32:34Z","timestamp":1773775954000},"page":"3279-3280","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["MUC1: Friend, Foe, or Bystander of Pouchitis?"],"prefix":"10.1007","volume":"71","author":[{"given":"Maya","family":"Fischman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keren M.","family":"Rabinowitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,3,17]]},"reference":[{"key":"9838_CR1","doi-asserted-by":"publisher","first-page":"610","DOI":"10.1053\/j.gastro.2019.10.001","volume":"158","author":"V Dubinsky","year":"2020","unstructured":"Dubinsky V, Reshef L, Bar N et al. Predominantly antibiotic-resistant intestinal microbiome persists in patients with pouchitis who respond to antibiotic therapy. Gastroenterology. 2020;158:610\u2013624. https:\/\/doi.org\/10.1053\/j.gastro.2019.10.001.","journal-title":"Gastroenterology."},{"key":"9838_CR2","doi-asserted-by":"publisher","first-page":"2509","DOI":"10.1097\/01.MIB.0000437045.26036.00","volume":"19","author":"S Ben-Shachar","year":"2013","unstructured":"Ben-Shachar S, Yanai H, Baram L et al. Gene expression profiles of ileal inflammatory bowel disease correlate with disease phenotype and advance understanding of its immunopathogenesis. Inflamm Bowel Dis. 2013;19:2509\u20132521. https:\/\/doi.org\/10.1097\/01.MIB.0000437045.26036.00.","journal-title":"Inflamm Bowel Dis."},{"key":"9838_CR3","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1093\/ecco-jcc\/jjae155","volume":"19","author":"W Arras","year":"2025","unstructured":"Arras W, Breugelmans T, Oosterlinck B et al. The intestinal mucin isoform landscape reveals region-specific biomarker panels for inflammatory bowel disease patient stratification. J Crohns Colitis. 2025;19:155. https:\/\/doi.org\/10.1093\/ecco-jcc\/jjae155.","journal-title":"J Crohns Colitis."},{"key":"9838_CR4","doi-asserted-by":"publisher","first-page":"2142","DOI":"10.1136\/gutjnl-2018-317571","volume":"68","author":"S van der Post","year":"2019","unstructured":"van der Post S, Jabbar KS, Birchenough G et al. Structural weakening of the colonic mucus barrier is an early event in ulcerative colitis pathogenesis. Gut. 2019;68:2142\u20132151. https:\/\/doi.org\/10.1136\/gutjnl-2018-317571.","journal-title":"Gut."},{"key":"9838_CR5","doi-asserted-by":"publisher","first-page":"2382324","DOI":"10.1080\/19490976.2024.2382324","volume":"16","author":"A Ambat","year":"2024","unstructured":"Ambat A, Antony L, Maji A et al. Enhancing recovery from gut microbiome dysbiosis and alleviating DSS-induced colitis in mice with a consortium of rare short-chain fatty acid-producing bacteria. Gut Microbes. 2024;16:2382324. https:\/\/doi.org\/10.1080\/19490976.2024.2382324.","journal-title":"Gut Microbes."},{"key":"9838_CR6","doi-asserted-by":"publisher","first-page":"15064","DOI":"10.1073\/pnas.0803124105","volume":"105","author":"MEV Johansson","year":"2008","unstructured":"Johansson MEV, Phillipson M, Petersson J, Velcich A, Holm L, Hansson GC. The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria. Proc Natl Acad Sci U S A. 2008;105:15064\u201315069. https:\/\/doi.org\/10.1073\/pnas.0803124105.","journal-title":"Proc Natl Acad Sci U S A."},{"key":"9838_CR7","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-025-09612-9","author":"CG Olson","year":"2025","unstructured":"Olson CG, Francis FF, Yan IK et al. Abnormal MUC1 expression as a biomarker for pouchitis. Dig Dis Sci. 2025. https:\/\/doi.org\/10.1007\/s10620-025-09612-9.","journal-title":"Dig Dis Sci"},{"key":"9838_CR8","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1016\/j.jcmgh.2022.06.010","volume":"14","author":"YH Sheng","year":"2022","unstructured":"Sheng YH, Davies JM, Wang R et al. MUC1-mediated macrophage activation promotes colitis-associated colorectal cancer via activating the interleukin-6\/ signal transducer and activator of transcription 3 axis. Cell Mol Gastroenterol Hepatol. 2022;14:789\u2013811. https:\/\/doi.org\/10.1016\/j.jcmgh.2022.06.010.","journal-title":"Cell Mol Gastroenterol Hepatol."},{"key":"9838_CR9","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2205277119","volume":"119","author":"G Cantero-Recasens","year":"2022","unstructured":"Cantero-Recasens G, Burballa C, Ohkawa Y et al. The ulcerative colitis-associated gene FUT8 regulates the quantity and quality of secreted mucins. Proc Natl Acad Sci U S A. 2022;119:2205277119. https:\/\/doi.org\/10.1073\/pnas.2205277119.","journal-title":"Proc Natl Acad Sci U S A."},{"key":"9838_CR10","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1097\/MCG.0000000000001340","volume":"55","author":"JG Hashash","year":"2021","unstructured":"Hashash JG, Beatty PL, Critelli K et al. Altered expression of the epithelial mucin muc1 accompanies endoscopic recurrence of postoperative crohn\u2019s disease. J Clin Gastroenterol. 2021;55:127\u2013133. https:\/\/doi.org\/10.1097\/MCG.0000000000001340.","journal-title":"J Clin Gastroenterol."}],"container-title":["Digestive Diseases and Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-026-09838-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10620-026-09838-1","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-026-09838-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T03:01:13Z","timestamp":1787540473000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10620-026-09838-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,17]]},"references-count":10,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["9838"],"URL":"https:\/\/doi.org\/10.1007\/s10620-026-09838-1","relation":{},"ISSN":["0163-2116","1573-2568"],"issn-type":[{"value":"0163-2116","type":"print"},{"value":"1573-2568","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,17]]},"assertion":[{"value":"26 February 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 March 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 March 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}