{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T14:16:24Z","timestamp":1789049784002,"version":"build-2803163510"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T00:00:00Z","timestamp":1779840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T00:00:00Z","timestamp":1779840000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Dig Dis Sci"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1007\/s10620-026-10001-z","type":"journal-article","created":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T04:33:05Z","timestamp":1779856385000},"page":"4675-4685","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Trends in Incidence and Prevalence of Acute Pancreatitis in the United States: A Population-Based Analysis from 1995 to 2024"],"prefix":"10.1007","volume":"71","author":[{"given":"Daniel Martin","family":"Simadibrata","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zaid","family":"Al-Fakhouri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laith","family":"Alomari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard C. K.","family":"Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,27]]},"reference":[{"key":"10001_CR1","doi-asserted-by":"publisher","first-page":"1000","DOI":"10.1053\/j.gastro.2024.12.029","volume":"168","author":"AF Peery","year":"2025","unstructured":"Peery AF, Murphy CC, Anderson C, Jensen ET, Deutsch-Link S, Egberg MD et al. Burden and Cost of Gastrointestinal, Liver, and Pancreatic Diseases in the United States: Update 2024. Gastroenterology. 2025;168:1000\u20131024.","journal-title":"Gastroenterology."},{"key":"10001_CR2","doi-asserted-by":"crossref","unstructured":"McNabb-Baltar J, Ravi P, Isabwe GA, Suleiman SL, Yaghoobi M, Trinh Q-D, et al. A Population-Based Assessment of the Burden of Acute Pancreatitis in the United States. Pancreas. 2014;43(5).","DOI":"10.1097\/MPA.0000000000000123"},{"key":"10001_CR3","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1053\/j.gastro.2024.02.052","volume":"167","author":"G Trikudanathan","year":"2024","unstructured":"Trikudanathan G, Yazici C, Evans Phillips A, Forsmark CE. Diagnosis and Management of Acute Pancreatitis. Gastroenterology. 2024;167:673\u2013688.","journal-title":"Gastroenterology."},{"key":"10001_CR4","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1186\/s12876-021-01906-2","volume":"21","author":"CL Li","year":"2021","unstructured":"Li CL, Jiang M, Pan CQ, Li J, Xu LG. The global, regional, and national burden of acute pancreatitis in 204 countries and territories, 1990\u20132019. BMC Gastroenterol. 2021;21:332.","journal-title":"BMC Gastroenterol."},{"key":"10001_CR5","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1001\/jama.2020.20317","volume":"325","author":"MA Mederos","year":"2021","unstructured":"Mederos MA, Reber HA, Girgis MD. Acute Pancreatitis: A Review. JAMA. 2021;325:382\u2013390.","journal-title":"JAMA."},{"key":"10001_CR6","unstructured":"Zhang H, Zhou X-D, Shapiro MD, Lip GYH, Tilg H, Valenti L, et al. Global burden of metabolic diseases, 1990&#x2013;2021. Metabolism - Clinical and Experimental. 2024;160."},{"key":"10001_CR7","doi-asserted-by":"publisher","first-page":"398","DOI":"10.1186\/s12876-024-03481-8","volume":"24","author":"T Li","year":"2024","unstructured":"Li T, Qin C, Zhao B, Li Z, Zhao Y, Lin C et al. Global and regional burden of pancreatitis: epidemiological trends, risk factors, and projections to 2050 from the global burden of disease study 2021. BMC Gastroenterology. 2024;24:398.","journal-title":"BMC Gastroenterology."},{"key":"10001_CR8","first-page":"253","volume":"34","author":"S Sharma","year":"2021","unstructured":"Sharma S, Nehme C, Aziz M, Weissman S, Khan A, Acharya A et al. Acute biliary pancreatitis has better outcomes but increased resource utilization compared to acute alcohol-induced pancreatitis: insights from a nationwide study. Ann Gastroenterol. 2021;34:253\u2013261.","journal-title":"Ann Gastroenterol."},{"key":"10001_CR9","doi-asserted-by":"publisher","first-page":"828","DOI":"10.1016\/j.pan.2022.07.002","volume":"22","author":"M Horibe","year":"2022","unstructured":"Horibe M, Ravella B, Chandra S, Sharma A, Sato Y, Vege SS. Trends in the incidence and etiology of acute pancreatitis from 2000 to 2016: A population-based study. Pancreatology. 2022;22:828\u2013829.","journal-title":"Pancreatology."},{"key":"10001_CR10","doi-asserted-by":"crossref","unstructured":"Yeo YH, Rezaie A, Hsieh TY-J, Hu X, Gaddam S, Ma KS-K, et al. Shifting Trends in the Indication of Glucagon-like Peptide-1 Receptor Agonist Prescriptions: A Nationwide Analysis. Annals of Internal Medicine. 2024;177(9):1289\u201391.","DOI":"10.7326\/M24-0019"},{"key":"10001_CR11","doi-asserted-by":"crossref","unstructured":"Kim M, Schweitzer MA, Kim JS, Alexander GC, Mehta HB. Use of Glucagon-Like Peptide-1 Agonists Among Individuals Undergoing Bariatric Surgery in the US. JAMA Surgery. 2025.","DOI":"10.1001\/jamasurg.2025.3089"},{"key":"10001_CR12","doi-asserted-by":"crossref","unstructured":"Wang Y, Song Y, Siu R, Nimma IR, Yan Y, Savage TR, et al. Validation of 13\u00a0102 International Classification of Diseases, Tenth Revision, Clinical Modification codes using a large language model-based system. Journal of the American Medical Informatics Association. 2026:ocag008.","DOI":"10.1093\/jamia\/ocag008"},{"key":"10001_CR13","unstructured":"Epidemiology CNCfHSDoAa. Age adjustment: CDC National Center for Health Statistics; 2024 [updated June 9, 2025. Available from: https:\/\/www.cdc.gov\/nchs\/hus\/sources-definitions\/age-adjustment.htm."},{"key":"10001_CR14","unstructured":"Anderson RN, Rosenberg HM. Age standardization of death rates; implementation of the year 2000 standard. 1998."},{"key":"10001_CR15","doi-asserted-by":"publisher","first-page":"h2750","DOI":"10.1136\/bmj.h2750","volume":"350","author":"E Kontopantelis","year":"2015","unstructured":"Kontopantelis E, Doran T, Springate DA, Buchan I, Reeves D. Regression based quasi-experimental approach when randomisation is not an option: interrupted time series analysis. Bmj. 2015;350:h2750.","journal-title":"Bmj."},{"key":"10001_CR16","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jclinepi.2020.02.006","volume":"122","author":"SL Turner","year":"2020","unstructured":"Turner SL, Karahalios A, Forbes AB, Taljaard M, Grimshaw JM, Cheng AC et al. Design characteristics and statistical methods used in interrupted time series studies evaluating public health interventions: a review. J Clin Epidemiol. 2020;122:1\u201311.","journal-title":"J Clin Epidemiol."},{"key":"10001_CR17","doi-asserted-by":"publisher","first-page":"2022942","DOI":"10.1001\/jamanetworkopen.2020.22942","volume":"3","author":"MS Pollard","year":"2020","unstructured":"Pollard MS, Tucker JS, Green HD Jr. Changes in Adult Alcohol Use and Consequences During the COVID-19 Pandemic in the US. JAMA Network Open. 2020;3:2022942.","journal-title":"JAMA Network Open."},{"key":"10001_CR18","doi-asserted-by":"publisher","first-page":"3113","DOI":"10.1111\/dom.16318","volume":"27","author":"RM Radwan","year":"2025","unstructured":"Radwan RM, Lee YA, Kotecha P, Wright DR, Hernandez I, Ramon R et al. Regional trends and disparities in newer GLP1 receptor agonist initiation among real-world adult patients eligible for obesity treatment. Diabetes Obes Metab. 2025;27:3113\u20133123.","journal-title":"Diabetes Obes Metab."},{"key":"10001_CR19","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1053\/j.gastro.2018.04.013","volume":"155","author":"ZM Sellers","year":"2018","unstructured":"Sellers ZM, MacIsaac D, Yu H, Dehghan M, Zhang KY, Bensen R et al. Nationwide Trends in Acute and Chronic Pancreatitis Among Privately Insured Children and Non-Elderly Adults in the United States, 2007\u20132014. Gastroenterology. 2018;155:469\u201378.e1.","journal-title":"Gastroenterology."},{"key":"10001_CR20","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1016\/j.bpg.2014.07.013","volume":"28","author":"L Bonfrate","year":"2014","unstructured":"Bonfrate L, Wang DQ, Garruti G, Portincasa P. Obesity and the risk and prognosis of gallstone disease and pancreatitis. Best Pract Res Clin Gastroenterol. 2014;28:623\u2013635.","journal-title":"Best Pract Res Clin Gastroenterol."},{"key":"10001_CR21","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1186\/s12986-023-00741-4","volume":"20","author":"J Zhang","year":"2023","unstructured":"Zhang J, Chen L, Shen K, Zhang J, Zhu Y, Qiao Q et al. Association between metabolically healthy overweight\/obesity and gallstones in Chinese adults. Nutr Metab (Lond). 2023;20:20.","journal-title":"Nutr Metab (Lond)."},{"key":"10001_CR22","doi-asserted-by":"publisher","first-page":"1443575","DOI":"10.3389\/fnut.2024.1443575","volume":"11","author":"T Yang","year":"2024","unstructured":"Yang T, Zhong J, Zhang R, Xiao F, Wang Y, Tao H et al. Different types and numbers metabolic abnormalities and risk of gallbladder stone disease in adults. Front Nutr. 2024;11:1443575.","journal-title":"Front Nutr."},{"key":"10001_CR23","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1016\/j.pan.2022.04.013","volume":"22","author":"H Chaffin","year":"2022","unstructured":"Chaffin H, Trivedi S, Singh VP. Impact of abdominal imaging on the diagnosis of acute pancreatitis in patients with painless lipase elevation. Pancreatology. 2022;22:547\u2013552.","journal-title":"Pancreatology."},{"key":"10001_CR24","doi-asserted-by":"publisher","first-page":"2461990","DOI":"10.1001\/jamanetworkopen.2024.61990","volume":"8","author":"O Chapman","year":"2025","unstructured":"Chapman O, Djerboua M, Rai M, Bechara R, Flemming JA. Alcohol-Associated Pancreatitis and Liver Disease Among Adolescents and Young Adults. JAMA Network Open. 2025;8:2461990.","journal-title":"JAMA Network Open."},{"key":"10001_CR25","doi-asserted-by":"publisher","first-page":"654","DOI":"10.1111\/acer.70001","volume":"49","author":"SD Stewart","year":"2025","unstructured":"Stewart SD. Work\u2013family\u2013self-care and day drinking among women during the COVID-19 pandemic. Alcohol, Clinical and Experimental Research. 2025;49:654\u2013664.","journal-title":"Alcohol, Clinical and Experimental Research."},{"key":"10001_CR26","doi-asserted-by":"publisher","first-page":"1958","DOI":"10.1053\/j.gastro.2020.07.016","volume":"159","author":"\u00c1 Meczker","year":"2020","unstructured":"Meczker \u00c1, Han\u00e1k L, P\u00e1rniczky A, Szentesi A, Er\u0151ss B, Hegyi P et al. Analysis of 1060 Cases of Drug-Induced Acute Pancreatitis. Gastroenterology. 2020;159:1958\u201361.e8.","journal-title":"Gastroenterology."},{"key":"10001_CR27","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1002\/cpt.3139","volume":"115","author":"D Li","year":"2024","unstructured":"Li D, Wang H, Qin C, Du D, Wang Y, Du Q et al. Drug-Induced Acute Pancreatitis: A Real-World Pharmacovigilance Study Using the FDA Adverse Event Reporting System Database. Clinical Pharmacology & Therapeutics. 2024;115:535\u2013544.","journal-title":"Clinical Pharmacology & Therapeutics."},{"key":"10001_CR28","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1007\/s40200-024-01552-x","volume":"24","author":"JH Gu","year":"2025","unstructured":"Gu JH, Samarneh M. Dose-dependent pancreatitis risk associated with GLP-1 agonists. J Diabetes Metab Disord. 2025;24:33.","journal-title":"J Diabetes Metab Disord."},{"key":"10001_CR29","doi-asserted-by":"crossref","unstructured":"Sarraf P, Agrawal R, Alrashdan H, Agarwal M, Boulay B, Mutlu ER, et al. Racial and Ethnic Minorities With Acute Pancreatitis Live in Neighborhoods With Higher Social Vulnerability Scores. Pancreas. 2024;53(4).","DOI":"10.1097\/MPA.0000000000002308"},{"key":"10001_CR30","doi-asserted-by":"crossref","unstructured":"Ghosh N, Nadeem MA, Khan A, Aguilar GJ, Salar K, Sohail AH, et al. A comparative analysis of gender and racial disparities in acute necrotizing pancreatitis outcomes: Insights from the national inpatient sample database. Pancreatology. 2025.","DOI":"10.1016\/j.pan.2025.08.016"},{"key":"10001_CR31","first-page":"174","volume":"10","author":"JM Buscaglia","year":"2009","unstructured":"Buscaglia JM, Kapoor S, Jagannath SB, Krishnamurty DM, Shin EJ, Okolo PI 3rd. Disparities in demographics among patients with pancreatitis-related mortality. Jop. 2009;10:174\u2013180.","journal-title":"Jop."}],"container-title":["Digestive Diseases and Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-026-10001-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10620-026-10001-z","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-026-10001-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T14:01:52Z","timestamp":1789048912000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10620-026-10001-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,27]]},"references-count":31,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["10001"],"URL":"https:\/\/doi.org\/10.1007\/s10620-026-10001-z","relation":{},"ISSN":["0163-2116","1573-2568"],"issn-type":[{"value":"0163-2116","type":"print"},{"value":"1573-2568","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,27]]},"assertion":[{"value":"2 April 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 May 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 May 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Richard CK Wong, MD: Consultant-Vascular Technology, Inc.; United States Endoscopy Group, Inc. (Steris).\u00a0The other authors declare no conflicts of interest.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}}]}}