{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T07:02:25Z","timestamp":1789628545417,"version":"build-2803163510"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T00:00:00Z","timestamp":1784678400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T00:00:00Z","timestamp":1784678400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Dig Dis Sci"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1007\/s10620-026-10123-4","type":"journal-article","created":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T16:08:09Z","timestamp":1784736489000},"page":"5711-5719","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Results of Laparoscopic Heller Myotomy in Achalasia Patients with Persistent or Recurrent Symptoms After Peroral Endoscopic Myotomy (POEM)"],"prefix":"10.1007","volume":"71","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3721-8279","authenticated-orcid":false,"given":"Elise M.","family":"Wessels","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gwen M. C.","family":"Masclee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marlies P.","family":"Schijven","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert J.","family":"Bredenoord","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,22]]},"reference":[{"key":"10123_CR1","doi-asserted-by":"publisher","first-page":"378","DOI":"10.5056\/jnm16177","volume":"23","author":"HH Jeon","year":"2017","unstructured":"Jeon HH, Kim JH, Youn YH et al. Clinical characteristics of patients with untreated achalasia. J Neurogastroenterol Motil. 2017;23:378\u2013384.","journal-title":"J Neurogastroenterol Motil."},{"key":"10123_CR2","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1055\/s-0029-1244080","volume":"42","author":"H Inoue","year":"2010","unstructured":"Inoue H, Minami H, Kobayashi Y et al. Peroral endoscopic myotomy (POEM) for esophageal achalasia. Endoscopy. 2010;42:265\u2013271.","journal-title":"Endoscopy."},{"key":"10123_CR3","doi-asserted-by":"publisher","first-page":"1241","DOI":"10.1080\/17474124.2023.2286279","volume":"17","author":"EM Wessels","year":"2023","unstructured":"Wessels EM, Masclee GMC, Bredenoord AJ. An overview of the efficacy, safety, and predictors of achalasia treatments. Expert Rev Gastroenterol Hepatol. 2023;17:1241\u20131254.","journal-title":"Expert Rev Gastroenterol Hepatol."},{"key":"10123_CR4","doi-asserted-by":"publisher","first-page":"1103","DOI":"10.1016\/S2468-1253(22)00300-4","volume":"7","author":"T Kuipers","year":"2022","unstructured":"Kuipers T, Ponds FA, Fockens P et al. Peroral endoscopic myotomy versus pneumatic dilation in treatment-naive patients with achalasia: 5-year follow-up of a randomised controlled trial. Lancet Gastroenterol Hepatol. 2022;7:1103\u20131111.","journal-title":"Lancet Gastroenterol Hepatol."},{"key":"10123_CR5","doi-asserted-by":"publisher","first-page":"732","DOI":"10.1136\/gutjnl-2015-310602","volume":"65","author":"A Moonen","year":"2016","unstructured":"Moonen A, Annese V, Belmans A et al. Long-term results of the European achalasia trial: a multicentre randomised controlled trial comparing pneumatic dilation versus laparoscopic Heller myotomy. Gut. 2016;65:732\u2013739.","journal-title":"Gut."},{"key":"10123_CR6","doi-asserted-by":"publisher","first-page":"2219","DOI":"10.1056\/NEJMoa1905380","volume":"381","author":"YB Werner","year":"2019","unstructured":"Werner YB, Hakanson B, Martinek J et al. Endoscopic or surgical myotomy in patients with idiopathic achalasia. N Engl J Med. 2019;381:2219\u20132229.","journal-title":"N Engl J Med."},{"key":"10123_CR7","doi-asserted-by":"crossref","unstructured":"Hugova K, Mares J, Hakanson B, et al. Per-oral endoscopic myotomy versus laparoscopic Heller\u2019s myotomy plus Dor fundoplication in patients with idiopathic achalasia: 5-year follow-up of a multicentre, randomised, open-label, non-inferiority trial. Lancet Gastroenterol Hepatol. 2025.","DOI":"10.1016\/S2468-1253(25)00012-3"},{"key":"10123_CR8","doi-asserted-by":"publisher","first-page":"7667","DOI":"10.1007\/s00464-023-10314-4","volume":"37","author":"EA El-Magd","year":"2023","unstructured":"El-Magd EA, Elgeidie A, Elmahdy Y et al. Pre-operative endoscopic balloon dilatation and its impact on outcome of laparoscopic Heller cardiomyotomy for patients with achalasia: does the frequency and interval matter? Surg Endosc. 2023;37:7667\u20137675.","journal-title":"Surg Endosc."},{"key":"10123_CR9","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1055\/a-0658-5783","volume":"51","author":"ZQ Liu","year":"2019","unstructured":"Liu ZQ, Li QL, Chen WF et al. The effect of prior treatment on clinical outcomes in patients with achalasia undergoing peroral endoscopic myotomy. Endoscopy. 2019;51:307\u2013316.","journal-title":"Endoscopy."},{"key":"10123_CR10","doi-asserted-by":"publisher","first-page":"1108","DOI":"10.1053\/j.gastro.2023.02.048","volume":"164","author":"CMG Saleh","year":"2023","unstructured":"Saleh CMG, Familiari P, Bastiaansen BAJ et al. The efficacy of peroral endoscopic myotomy vs pneumatic dilation as treatment for patients with achalasia suffering from persistent or recurrent symptoms after laparoscopic heller myotomy: a randomized clinical trial. Gastroenterology. 2023;164:1108-18e3.","journal-title":"Gastroenterology."},{"key":"10123_CR11","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1016\/S1052-5157(18)30071-0","volume":"11","author":"VF Eckardt","year":"2001","unstructured":"Eckardt VF. Clinical presentations and complications of achalasia. Gastrointest Endosc Clin N Am. 2001;11:281\u201392vi.","journal-title":"Gastrointest Endosc Clin N Am."},{"key":"10123_CR12","doi-asserted-by":"crossref","unstructured":"Wessels EM, Mussies CM, Masclee GMC, et al. Translation and cross-sectional validation of the achalasia patient reported outcomes questionnaire in a Dutch cohort. BMC Gastroenterol. 2026;26(1).","DOI":"10.1186\/s12876-026-04724-6"},{"key":"10123_CR13","doi-asserted-by":"publisher","first-page":"564","DOI":"10.1111\/apt.12204","volume":"37","author":"C Jonasson","year":"2013","unstructured":"Jonasson C, Wernersson B, Hoff DA et al. Validation of the GerdQ questionnaire for the diagnosis of gastro-oesophageal reflux disease. Aliment Pharmacol Ther. 2013;37:564\u2013572.","journal-title":"Aliment Pharmacol Ther."},{"key":"10123_CR14","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1159\/000100511","volume":"74","author":"MC Aanen","year":"2006","unstructured":"Aanen MC, Numans ME, Weusten BL et al. Diagnostic value of the reflux disease questionnaire in general practice. Digestion. 2006;74:162\u2013168.","journal-title":"Digestion."},{"key":"10123_CR15","doi-asserted-by":"publisher","first-page":"544","DOI":"10.1111\/j.1442-2050.2008.00815.x","volume":"21","author":"R Frankhuisen","year":"2008","unstructured":"Frankhuisen R, Heijkoop R, van Herwaarden MA et al. Validation of a disease-specific quality-of-life questionnaire in a large sample of Dutch achalasia patients. Dis Esophagus. 2008;21:544\u2013550.","journal-title":"Dis Esophagus."},{"key":"10123_CR16","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1177\/2050640620903213","volume":"8","author":"RAB Oude Nijhuis","year":"2020","unstructured":"Oude Nijhuis RAB, Zaninotto G, Roman S et al. European guidelines on achalasia: united European gastroenterology and European society of neurogastroenterology and motility recommendations. United European Gastroenterol J. 2020;8:13\u201333.","journal-title":"United European Gastroenterol J."},{"key":"10123_CR17","doi-asserted-by":"publisher","first-page":"1003","DOI":"10.1055\/a-1312-0496","volume":"53","author":"Y Ichkhanian","year":"2021","unstructured":"Ichkhanian Y, Assis D, Familiari P et al. Management of patients after failed peroral endoscopic myotomy: a multicenter study. Endoscopy. 2021;53:1003\u20131010.","journal-title":"Endoscopy."},{"key":"10123_CR18","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/j.gie.2017.04.036","volume":"87","author":"FB van Hoeij","year":"2018","unstructured":"van Hoeij FB, Ponds FA, Werner Y et al. Management of recurrent symptoms after per-oral endoscopic myotomy in achalasia. Gastrointest Endosc. 2018;87:95\u2013101.","journal-title":"Gastrointest Endosc."},{"key":"10123_CR19","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1186\/s40792-023-01691-y","volume":"9","author":"T Aoki","year":"2023","unstructured":"Aoki T, Ozawa S, Hayashi K et al. Laparoscopic heller myotomy and Dor fundoplication following an unsuccessful peroral endoscopic myotomy. Surg Case Rep. 2023;9:106.","journal-title":"Surg Case Rep."},{"key":"10123_CR20","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1007\/s00104-016-0332-9","volume":"88","author":"L Giulini","year":"2017","unstructured":"Giulini L, Dubecz A, Stein HJ. Laparoscopic heller myotomy after failed POEM and multiple balloon dilatations: better late than never. Chirurg. 2017;88:303\u2013306.","journal-title":"Chirurg."},{"key":"10123_CR21","doi-asserted-by":"publisher","first-page":"1071","DOI":"10.1007\/s11605-018-3847-1","volume":"23","author":"CG Yheulon","year":"2019","unstructured":"Yheulon CG, Brock PB, Balla FM et al. Laparoscopic heller myotomy and hiatal hernia repair after failed peroral endoscopic myotomy. J Gastrointest Surg. 2019;23:1071\u20131072.","journal-title":"J Gastrointest Surg."},{"key":"10123_CR22","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1097\/MOG.0000000000001024","volume":"40","author":"MG Patti","year":"2024","unstructured":"Patti MG, Herbella FA. Laparoscopic heller myotomy versus peroral endoscopic myotomy for the treatment of achalasia. Curr Opin Gastroenterol. 2024;40:314\u2013318.","journal-title":"Curr Opin Gastroenterol."},{"key":"10123_CR23","doi-asserted-by":"publisher","first-page":"2536","DOI":"10.1001\/jama.2020.21360","volume":"324","author":"J Maret-Ouda","year":"2020","unstructured":"Maret-Ouda J, Markar SR, Lagergren J. Gastroesophageal reflux disease: a review. JAMA. 2020;324:2536\u20132547.","journal-title":"JAMA."},{"key":"10123_CR24","doi-asserted-by":"publisher","first-page":"1983","DOI":"10.14309\/ajg.0000000000002816","volume":"119","author":"T Kuipers","year":"2024","unstructured":"Kuipers T, Ponds FA, Fockens P et al. Focal distal esophageal dilation (blown-out myotomy) after achalasia treatment: prevalence and associated symptoms. Am J Gastroenterol. 2024;119:1983\u20131989.","journal-title":"Am J Gastroenterol."},{"key":"10123_CR25","doi-asserted-by":"publisher","first-page":"1208","DOI":"10.1016\/j.gie.2016.10.015","volume":"85","author":"A Tyberg","year":"2017","unstructured":"Tyberg A, Seewald S, Sharaiha RZ et al. A multicenter international registry of redo per-oral endoscopic myotomy (POEM) after failed POEM. Gastrointest Endosc. 2017;85:1208\u20131211.","journal-title":"Gastrointest Endosc."},{"key":"10123_CR26","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1016\/j.gie.2023.04.2093","volume":"98","author":"ZC Zhang","year":"2023","unstructured":"Zhang ZC, Xu JQ, Liu XY et al. Salvage peroral endoscopic myotomy is a promising treatment for achalasia after myotomy failure. Gastrointest Endosc. 2023;98:543\u201351 e1.","journal-title":"Gastrointest Endosc."},{"key":"10123_CR27","unstructured":"Ma LY, Guo KY, Liu ZQ, et al. Repeat peroral endoscopic myotomy: technical difficulty and risk factors. Gastrointest Endosc. 2024."},{"key":"10123_CR28","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/j.gie.2020.05.056","volume":"93","author":"Z Huang","year":"2021","unstructured":"Huang Z, Cui Y, Li Y et al. Peroral endoscopic myotomy for patients with achalasia with previous Heller myotomy: a systematic review and meta-analysis. Gastrointest Endosc. 2021;93:47-56 e5.","journal-title":"Gastrointest Endosc."},{"key":"10123_CR29","doi-asserted-by":"crossref","unstructured":"Wessels EM, Masclee GMC, Bastiaansen BAJ, et al. Long-Term Outcomes of Peroral Endoscopic Myotomy vs Pneumatic Dilation After Prior Laparoscopic Heller Myotomy for Achalasia. Clin Gastroenterol Hepatol. 2026.","DOI":"10.1016\/j.cgh.2026.03.024"},{"key":"10123_CR30","doi-asserted-by":"publisher","first-page":"1076","DOI":"10.1038\/ajg.2013.32","volume":"108","author":"V Kumbhari","year":"2013","unstructured":"Kumbhari V, Behary J, Szczesniak M et al. Efficacy and safety of pneumatic dilatation for achalasia in the treatment of post-myotomy symptom relapse. Am J Gastroenterol. 2013;108:1076\u20131081.","journal-title":"Am J Gastroenterol."}],"container-title":["Digestive Diseases and Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-026-10123-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10620-026-10123-4","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-026-10123-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T06:08:20Z","timestamp":1789625300000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10620-026-10123-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,22]]},"references-count":30,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2026,11]]}},"alternative-id":["10123"],"URL":"https:\/\/doi.org\/10.1007\/s10620-026-10123-4","relation":{},"ISSN":["0163-2116","1573-2568"],"issn-type":[{"value":"0163-2116","type":"print"},{"value":"1573-2568","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,22]]},"assertion":[{"value":"27 October 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 July 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 July 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"EMW, GMCM, and MPS have nothing to declare. AJB received research funding from Dr. Falk Pharma, Thelial, Sanofi\/Regeneron and Side Sleep Technologies (SST) and received speaker and\/or consulting fees from Laborie, Medtronic, BMS, Dr. Falk Pharma, Reckitt, Aqilion, Eupraxia, Uniquity, Alimentiv, Aquilion, Sanofi\/Regeneron, and AstraZeneca.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}}]}}