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The following data were ascertained in each participant at baseline and at 1, 3, 6, 9 and 12\u00a0months following implanting procedure: intraocular pressure, number of anti-glaucoma medications, retinal sensitivity (PS 24\/2 w\/w), pattern electroretinogram (ISCEV standard), as well as the number of complications.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>The mean intraocular pressure reduction in a 1-year follow-up was 18% (21.56 vs. 17.69\u00a0mmHg, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). The mean number of anti-glaucoma medications was reduced from 3.2 to 1.6 (<jats:italic>p<\/jats:italic>\u2009=\u20090.001). The PERG parameters at baseline and at 12\u00a0months postoperatively included a stable amplitude of P50 (2.55\u00a0\u00b5V vs. 2.65\u00a0\u00b5V, <jats:italic>p<\/jats:italic>\u2009=\u20090.024) and N95 (3.45\u00a0\u00b5V vs. 3.38\u00a0\u00b5V, <jats:italic>p<\/jats:italic>\u2009=\u2009ns) waves. The delta N95 and delta P50 amplitudes remained stable over the follow-up period (<jats:italic>p<\/jats:italic>\u2009=\u2009ns). The mean deviation (MD) of PS 24\/2 was \u2212\u20096.54\u00a0dB vs. \u2212\u20098.43\u00a0dB, <jats:italic>p<\/jats:italic>\u2009=\u2009ns, whereas the pattern standard deviation (PSD) was 6.18\u00a0dB vs. 6.91\u00a0dB, <jats:italic>p<\/jats:italic>\u2009=\u2009ns. Transient hypotony within the first postoperative week occurred in 18 eyes (90%), whereas hyphema occurred in two eyes (10%). Needle revision of a filtration bleb was performed in five eyes (25%).<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>The XEN Gel Stent enables significant reduction in intraocular pressure with very low complication rates. It ensures a stabilization of the retinal function as established with the PERG.<\/jats:p>\n<\/jats:sec>","DOI":"10.1007\/s10633-020-09753-4","type":"journal-article","created":{"date-parts":[[2020,2,12]],"date-time":"2020-02-12T17:02:42Z","timestamp":1581526962000},"page":"65-76","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["XEN Gel Stent in the management of primary open-angle glaucoma"],"prefix":"10.1007","volume":"141","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0166-3696","authenticated-orcid":false,"given":"Micha\u0142","family":"Post","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wojciech","family":"Lubi\u0144ski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominik","family":"\u015aliwiak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karolina","family":"Podbor\u0105czy\u0144ska-Jodko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maciej","family":"Mularczyk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,2,12]]},"reference":[{"key":"9753_CR1","doi-asserted-by":"publisher","first-page":"2081","DOI":"10.1016\/j.ophtha.2014.05.013","volume":"121","author":"Y-C Tham","year":"2014","unstructured":"Tham Y-C, Li X, Wong TY, Quigley HA, Aung T, Cheng C-Y (2014) Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis. 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