{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T06:17:07Z","timestamp":1771481827528,"version":"3.50.1"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2020,3,25]],"date-time":"2020-03-25T00:00:00Z","timestamp":1585094400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,3,25]],"date-time":"2020-03-25T00:00:00Z","timestamp":1585094400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"JSPS KAKENHI","award":["18K09420"],"award-info":[{"award-number":["18K09420"]}]},{"name":"Dokkyo Medical University Grant","award":["2016"],"award-info":[{"award-number":["2016"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Doc Ophthalmol"],"published-print":{"date-parts":[[2020,10]]},"DOI":"10.1007\/s10633-020-09762-3","type":"journal-article","created":{"date-parts":[[2020,3,25]],"date-time":"2020-03-25T21:02:34Z","timestamp":1585170154000},"page":"169-179","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Changes of focal macular and full-field electroretinograms after intravitreal aflibercept in patients with central retinal vein occlusion"],"prefix":"10.1007","volume":"141","author":[{"given":"Tomoharu","family":"Nishimura","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8671-2399","authenticated-orcid":false,"given":"Shigeki","family":"Machida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuji","family":"Hara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,3,25]]},"reference":[{"key":"9762_CR1","doi-asserted-by":"publisher","first-page":"5905","DOI":"10.1167\/iovs.11-7775","volume":"52","author":"S Arakawa","year":"2011","unstructured":"Arakawa S, Yasuda M, Nagata M, Ninomiya T, Hirakawa Y, Doi Y, Kiyohara Y, Ishibashi T (2011) Nine-year incidence and risk factors for retinal vein occlusion in a general Japanese population: the Hisayama Study. Invest Ophthalmol Vis Sci 52:5905\u20135909","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"9762_CR2","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1001\/archopht.1997.01100150488006","volume":"115","author":"The Central Vein Occlusion Study Group","year":"1997","unstructured":"The Central Vein Occlusion Study Group (1997) Natural history and clinical management of central retinal vein occlusion. The Central Vein Occlusion Study Group. Arch Ophthalmol 115:486\u2013491","journal-title":"Arch Ophthalmol"},{"key":"9762_CR3","doi-asserted-by":"publisher","first-page":"1124","DOI":"10.1016\/j.ophtha.2010.02.022","volume":"117","author":"DM Brown","year":"2010","unstructured":"Brown DM, Campochiaro PA, Singh RP, Li Z, Gray S, Saroj N, Rundle AC, Rubio RG, Murahashi WY, Investigators CRUISE (2010) Ranibizumab for macular edema following central retinal vein occlusion: six-month primary end point results of a phase III study. Ophthalmology 117:1124\u20131133","journal-title":"Ophthalmology"},{"key":"9762_CR4","doi-asserted-by":"publisher","first-page":"2041","DOI":"10.1016\/j.ophtha.2011.02.038","volume":"118","author":"PA Campochiaro","year":"2011","unstructured":"Campochiaro PA, Brown DM, Awh CC, Lee SY, Gray S, Saroj N, Murahashi WY, Rubio RG (2011) Sustained benefits from ranibizumab for macular edema following central retinal vein occlusion: twelve-month outcomes of a phase III study. Ophthalmology 118:2041\u20132049","journal-title":"Ophthalmology"},{"key":"9762_CR5","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1016\/j.ajo.2012.09.026","volume":"155","author":"DM Brown","year":"2013","unstructured":"Brown DM, Heier JS, Clark WL, Boyer DS, Vitti R, Berliner AJ, Zeitz O, Sandbrink R, Zhu X, Haller JA (2013) Intravitreal aflibercept injection for macular edema secondary to central retinal vein occlusion: 1-year results from the phase 3 COPERNICUS study. Am J Ophthalmol 155:429\u2013437","journal-title":"Am J Ophthalmol"},{"key":"9762_CR6","doi-asserted-by":"publisher","first-page":"1032","DOI":"10.1016\/j.ajo.2014.07.027","volume":"158","author":"Y Ogura","year":"2014","unstructured":"Ogura Y, Roider J, Korobelnik JF, Holz FG, Simader C, Schmidt-Erfurth U, Vitti R, Berliner AJ, Hiemeyer F, Stemper B, Zeitz O, Sandbrink R, GALILEO Study Group (2014) Intravitreal aflibercept for macular edema secondary to central retinal vein occlusion: 18-month results of the phase 3 GALILEO study. Am J Ophthalmol 158:1032\u20131038","journal-title":"Am J Ophthalmol"},{"key":"9762_CR7","doi-asserted-by":"publisher","first-page":"802","DOI":"10.1016\/j.ophtha.2011.12.005","volume":"119","author":"JS Heier","year":"2012","unstructured":"Heier JS, Campochiaro PA, Yau L, Li Z, Saroj N, Rubio RG, Lai P (2012) Ranibizumab for macular edema due to retinal vein occlusions: long-term follow-up in the HORIZON trial. Ophthalmology 119:802\u2013809","journal-title":"Ophthalmology"},{"key":"9762_CR8","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1007\/s00417-011-1860-0","volume":"250","author":"M Ota","year":"2012","unstructured":"Ota M, Tsujikawa A, Ojima Y, Miyamoto K, Murakami T, Ogino K, Akagi-Kurashige Y, Muraoka Y, Yoshimura N (2012) Retinal sensitivity after resolution of the macular edema associated with retinal vein occlusion. Graefes Arch Clin Exp Ophthalmol 250:635\u2013644","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"9762_CR9","doi-asserted-by":"publisher","first-page":"e0186737","DOI":"10.1371\/journal.pone.0186737","volume":"12","author":"K Manabe","year":"2017","unstructured":"Manabe K, Osaka R, Nakano Y, Takasago Y, Fujita T, Shiragami C, Hirooka K, Muraoka Y, Tsujikawa A (2017) Metamorphopsia associated with central retinal vein occlusion. PLoS ONE 12:e0186737","journal-title":"PLoS ONE"},{"key":"9762_CR10","doi-asserted-by":"publisher","first-page":"1063","DOI":"10.1007\/s00417-017-3597-x","volume":"255","author":"F Okamoto","year":"2017","unstructured":"Okamoto F, Sugiura Y, Okamoto Y, Hiraoka T, Oshika T (2017) Aniseikonia in various retinal disorders. Graefes Arch Clin Exp Ophthalmol 255:1063\u20131071","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"9762_CR11","doi-asserted-by":"publisher","first-page":"5854","DOI":"10.1167\/iovs.18-25087","volume":"59","author":"R Miyata","year":"2018","unstructured":"Miyata R, Kondo M, Kato K, Sugimoto M, Matsubara H, Ikesugi K, Ueno S, Yasuda S, Terasaki H (2018) Supernormal flicker ERGs in eyes with central retinal vein occlusion: clinical characteristics, prognosis, and effects of anti-VEGF agent. Invest Ophthalmol Vis Sci 59:5854\u20135861","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"9762_CR12","doi-asserted-by":"publisher","first-page":"e465","DOI":"10.1111\/aos.12674","volume":"93","author":"S Yasuda","year":"2015","unstructured":"Yasuda S, Kachi S, Ueno S, Piao CH, Terasaki H (2015) Flicker electroretinograms before and after intravitreal ranibizumab injection in eyes with central retinal vein occlusion. Acta Ophthalmol 93:e465\u2013e468","journal-title":"Acta Ophthalmol"},{"key":"9762_CR13","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1007\/s10633-014-9445-y","volume":"129","author":"I Garda\u0161evi\u0107 Top\u010di\u0107","year":"2014","unstructured":"Garda\u0161evi\u0107 Top\u010di\u0107 I, \u0160u\u0161tar M, Brecelj J, Hawlina M, Jaki Mekjavi\u0107 P (2014) Morphological and electrophysiological outcome in prospective intravitreal bevacizumab treatment of macular edema secondary to central retinal vein occlusion. Doc Ophthalmol 129:27\u201338","journal-title":"Doc Ophthalmol"},{"key":"9762_CR14","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1007\/s10633-007-9110-9","volume":"116","author":"MM Moschos","year":"2008","unstructured":"Moschos MM, Moschos M (2008) Intraocular bevacizumab for macular edema due to CRVO. A multifocal-ERG and OCT study. Doc Ophthalmol 116:147\u2013152","journal-title":"Doc Ophthalmol"},{"key":"9762_CR15","doi-asserted-by":"crossref","DOI":"10.1007\/4-431-30306-5","volume-title":"Electrodiagnosis of retinal diseases","author":"Y Miyake","year":"2006","unstructured":"Miyake Y (2006) Electrodiagnosis of retinal diseases. Springer, Tokyo"},{"key":"9762_CR16","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s10633-014-9473-7","volume":"130","author":"DL McCulloch","year":"2015","unstructured":"McCulloch DL, Marmor MF, Brigell MG, Hamilton R, Holder GE, Tzekov R, Bach M (2015) ISCEV Standard for full-field clinical electroretinography (2015 update). Doc Ophthalmol 130:1\u201312","journal-title":"Doc Ophthalmol"},{"key":"9762_CR17","first-page":"439","volume":"25","author":"Y Miyake","year":"1981","unstructured":"Miyake Y, Yanagida K, Kondo K, Ota I (1981) Subjective scotometry and recording of local electroretinogram and visual evoked response. System with television monitor of the fundus. Jpn J Ophthalmol 25:439\u2013448","journal-title":"Jpn J Ophthalmol"},{"key":"9762_CR18","first-page":"1419","volume":"92","author":"Y Miyake","year":"1988","unstructured":"Miyake Y (1988) Studies on local macular ERG. Acta Soc Ophthalmol Jpn 92:1419\u20131449","journal-title":"Acta Soc Ophthalmol Jpn"},{"key":"9762_CR19","doi-asserted-by":"publisher","first-page":"3514","DOI":"10.1167\/iovs.10-7142","volume":"52","author":"K Ogino","year":"2011","unstructured":"Ogino K, Tsujikawa A, Nakamura H, Miyamoto K, Murakami T, Muraoka Y, Kurashige Y, Yoshimura N (2011) Focal macular electroretinogram in macular edema secondary to central retinal vein occlusion. Invest Ophthalmol Vis Sci 52:3514\u20133520","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"9762_CR20","doi-asserted-by":"publisher","first-page":"5737","DOI":"10.1167\/iovs.10-6923","volume":"52","author":"S Yasuda","year":"2011","unstructured":"Yasuda S, Kachi S, Kondo M, Ushida H, Uetani R, Terui T, Piao CH, Terasaki H (2011) Significant correlation between electroretinogram parameters and ocular vascular endothelial growth factor concentration in central retinal vein occlusion eyes. Invest Ophthalmol Vis Sci 52:5737\u20135742","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"9762_CR21","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1007\/s10633-006-9015-z","volume":"113","author":"H Chen","year":"2006","unstructured":"Chen H, Wu D, Huang S, Yan H (2006) The photopic negative response of the flash electroretinogram in retinal vein occlusion. Doc Ophthalmol 113:53\u201359","journal-title":"Doc Ophthalmol"},{"key":"9762_CR22","doi-asserted-by":"publisher","first-page":"5636","DOI":"10.1167\/iovs.08-1946","volume":"49","author":"S Machida","year":"2008","unstructured":"Machida S, Toba Y, Ohtaki A, Gotoh Y, Kaneko M, Kurosaka D (2008) Photopic negative response of focal electroretinogram in glaucomatous eyes. Invest Ophthalmol Vis Sci 49:5636\u20135644","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"9762_CR23","doi-asserted-by":"publisher","first-page":"299","DOI":"10.2147\/OPTH.S16253","volume":"5","author":"VC Lima","year":"2011","unstructured":"Lima VC, Yeung L, Castro LC, Landa G, Rosen RB (2011) Correlation between spectral domain optical coherence tomography findings and visual outcomes in central retinal vein occlusion. Clin Ophthalmol 5:299\u2013305","journal-title":"Clin Ophthalmol"},{"key":"9762_CR24","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1016\/j.ajo.2013.10.007","volume":"157","author":"T Hasegawa","year":"2014","unstructured":"Hasegawa T, Ueda T, Okamoto M, Ogata N (2014) Presence of foveal bulge in optical coherence tomographic images in eyes with macular edema associated with branch retinal vein occlusion. Am J Ophthalmol 157:390\u2013396","journal-title":"Am J Ophthalmol"},{"key":"9762_CR25","first-page":"508","volume":"33","author":"P Gouras","year":"1992","unstructured":"Gouras P, MacKay CJ (1992) Supernormal cone electroretinograms in central retinal vein occlusion. Invest Ophthalmol Vis Sci 33:508\u2013515","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"9762_CR26","doi-asserted-by":"publisher","first-page":"938","DOI":"10.1016\/j.ajo.2003.10.023","volume":"37","author":"S Machida","year":"2004","unstructured":"Machida S, Gotoh Y, Tanaka M, Tazawa Y (2004) Predominant loss of the photopic negative response in central retinal artery occlusion. Am J Ophthalmol 37:938\u2013940","journal-title":"Am J Ophthalmol"},{"key":"9762_CR27","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1111\/j.1600-0420.2007.00920.x","volume":"85","author":"O Kjeka","year":"2007","unstructured":"Kjeka O, Bredrup C, Krohn J (2007) Photopic 30\u00a0Hz flicker electroretinography predicts ocular neovascularization in central retinal vein occlusion. Acta Ophthalmol Scand 85:640\u2013643","journal-title":"Acta Ophthalmol Scand"},{"key":"9762_CR28","doi-asserted-by":"publisher","first-page":"1113","DOI":"10.1016\/j.ophtha.2010.01.060","volume":"117","author":"RL McIntosh","year":"2010","unstructured":"McIntosh RL, Rogers SL, Lim L, Cheung N, Wang JJ, Mitchell P, Kowalski JW, Nguyen HP, Wong TY (2010) Natural history of central retinal vein occlusion: an evidence-based systematic review. Ophthalmology 117:1113\u20131123","journal-title":"Ophthalmology"},{"key":"9762_CR29","doi-asserted-by":"publisher","first-page":"1434","DOI":"10.1016\/S0161-6420(95)30848-2","volume":"102","author":"The Central Vein Occlusion Study Group","year":"1995","unstructured":"The Central Vein Occlusion Study Group (1995) A randomized clinical trial of early panretinal photocoagulation for ischemic central vein occlusion. The Central Vein Occlusion Study Group N report. Ophthalmology 102:1434\u20131444","journal-title":"Ophthalmology"}],"container-title":["Documenta Ophthalmologica"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10633-020-09762-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10633-020-09762-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10633-020-09762-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T03:39:58Z","timestamp":1695958798000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10633-020-09762-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,25]]},"references-count":29,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,10]]}},"alternative-id":["9762"],"URL":"https:\/\/doi.org\/10.1007\/s10633-020-09762-3","relation":{},"ISSN":["0012-4486","1573-2622"],"issn-type":[{"value":"0012-4486","type":"print"},{"value":"1573-2622","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3,25]]},"assertion":[{"value":"5 September 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 March 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 March 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"Shigeki Machida has received research grants from Bayer Yakuhin, Ltd. (Bayer).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of Dokkyo Medical University Saitama Medical Center and with the 1964 Declaration of Helsinki and later amendments or comparable ethical standards.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Statement of human rights"}},{"value":"No animals were used in this study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Statement of the welfare of animals"}},{"value":"Informed consent was obtained from all individual participants included in this study.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}