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The VEP trans-occipital distribution from the functional right eye was skewed markedly across the midline, in keeping with significant misrouting of optic nerve fibres at the chiasm. This was supported by the anatomical trajectory of the optic chiasm and tracts seen on MRI.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>This infant has chiasmal misrouting in association with unilateral optic nerve aplasia and unilateral microphthalmos. Chiasmal misrouting has not been found in patients with microphthalmos or anophthalmos, but has been reported after early eye loss in animal models. Our findings contribute to our understanding of the discrepancy between the visual pathway physiology of human unilateral microphthalmia and animal models.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s10633-020-09788-7","type":"journal-article","created":{"date-parts":[[2020,8,27]],"date-time":"2020-08-27T07:03:54Z","timestamp":1598511834000},"page":"247-255","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Case report: Unilateral optic nerve aplasia and developmental hemi-chiasmal dysplasia with VEP misrouting"],"prefix":"10.1007","volume":"142","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7612-3889","authenticated-orcid":false,"given":"Sian E.","family":"Handley","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2022-3669","authenticated-orcid":false,"given":"Oliver R.","family":"Marmoy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1645-4993","authenticated-orcid":false,"given":"Sri K.","family":"Gore","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5979-9337","authenticated-orcid":false,"given":"Kshitij","family":"Mankad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5491-3911","authenticated-orcid":false,"given":"Dorothy A.","family":"Thompson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,8,27]]},"reference":[{"key":"9788_CR1","doi-asserted-by":"publisher","first-page":"1393","DOI":"10.1152\/physrev.2001.81.4.1393","volume":"81","author":"G Jeffery","year":"2001","unstructured":"Jeffery G (2001) Architecture of the optic chiasm and the mechanisms that sculpt its development. 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