{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T07:43:23Z","timestamp":1740123803601,"version":"3.37.3"},"reference-count":9,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2020,12,23]],"date-time":"2020-12-23T00:00:00Z","timestamp":1608681600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2020,12,23]],"date-time":"2020-12-23T00:00:00Z","timestamp":1608681600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Projekt DEAL"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Doc Ophthalmol"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>It is well known that repetitive flash stimulation may trigger seizures in susceptible individuals. Nevertheless, reports of such incidents occurring during recording of a flash electroretinogram (ERG) are extremely rare. Here, we describe the case of a photic-induced seizure triggered during an ERG recording in the absence of a history of epilepsy or other paroxysmal events.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>A 14-year-old male patient presented with reduced visual acuity and impaired mesopic vision. Ophthalmological exams confirmed the patient\u2019s complaints but were inconclusive as to the underlying pathophysiology. An ERG recording was performed, during which the 30-Hz flicker stimulus triggered a seizure.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The ERG was essentially normal, with the exception of a 7-Hz rhythm superimposed onto the flicker ERG response that was recorded when the seizure developed.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>The present case highlights the possibility that the 30-Hz ERG flash stimulus triggers a seizure in patients with no previous paroxysmal events. Literature evidence suggests that the likelihood of such an incident could be reduced by stimulating monocularly.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s10633-020-09813-9","type":"journal-article","created":{"date-parts":[[2020,12,23]],"date-time":"2020-12-23T12:03:19Z","timestamp":1608724999000},"page":"389-393","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Seizure triggered by flicker electroretinogram in a patient with no history of epilepsy"],"prefix":"10.1007","volume":"142","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4906-3937","authenticated-orcid":false,"given":"Sven P.","family":"Heinrich","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hansj\u00fcrgen","family":"Agostini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,12,23]]},"reference":[{"key":"9813_CR1","doi-asserted-by":"publisher","first-page":"1426","DOI":"10.1111\/j.1528-1167.2005.31405.x","volume":"46","author":"RS Fisher","year":"2005","unstructured":"Fisher RS, Harding G, Erba G et al (2005) Photic- and pattern-induced seizures: a review for the Epilepsy Foundation of America Working Group. Epilepsia 46:1426\u20131441. https:\/\/doi.org\/10.1111\/j.1528-1167.2005.31405.x","journal-title":"Epilepsia"},{"key":"9813_CR2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s10633-014-9473-7","volume":"130","author":"DL McCulloch","year":"2015","unstructured":"McCulloch DL, Marmor MF, Brigell MG et al (2015) ISCEV standard for full-field clinical electroretinography (2015 update). Doc Ophthalmol 130:1\u201312. https:\/\/doi.org\/10.1007\/s10633-014-9473-7","journal-title":"Doc Ophthalmol"},{"key":"9813_CR3","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1186\/s12883-018-1051-2","volume":"18","author":"Y Hayashi","year":"2018","unstructured":"Hayashi Y, Miura G, Uzawa A et al (2018) Case of convulsive seizure developing during electroretinographic recordings: a case report. BMC Neurol 18:52. https:\/\/doi.org\/10.1186\/s12883-018-1051-2","journal-title":"BMC Neurol"},{"key":"9813_CR4","doi-asserted-by":"publisher","first-page":"1235","DOI":"10.1097\/00007611-200112000-00025","volume":"94","author":"BG Zifkin","year":"2001","unstructured":"Zifkin BG, Kasteleijn-Nolst Trenit\u00e9 DG (2001) Pokemon contagion. South Med J 94:1235\u20131236. https:\/\/doi.org\/10.1097\/00007611-200112000-00025","journal-title":"South Med J"},{"key":"9813_CR5","doi-asserted-by":"publisher","first-page":"733","DOI":"10.1002\/ana.410370606","volume":"37","author":"JA Quirk","year":"1995","unstructured":"Quirk JA, Fish DR, Smith SJ et al (1995) First seizures associated with playing electronic screen games: a community-based study in Great Britain. Ann Neurol 37:733\u2013737. https:\/\/doi.org\/10.1002\/ana.410370606","journal-title":"Ann Neurol"},{"key":"9813_CR6","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1053\/seiz.2001.0606","volume":"11","author":"Y Manabe","year":"2002","unstructured":"Manabe Y, Narai H, Warita H et al (2002) Benign adult familial myoclonic epilepsy (BAFME) with night blindness. Seizure 11:266\u2013268. https:\/\/doi.org\/10.1053\/seiz.2001.0606","journal-title":"Seizure"},{"key":"9813_CR7","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1007\/s11682-016-9517-6","volume":"11","author":"C-S Lu","year":"2017","unstructured":"Lu C-S, Ng S-H, Lai S-C et al (2017) Cortical damage in the posterior visual pathway in patients with sialidosis type 1. Brain Imaging Behav 11:214\u2013223. https:\/\/doi.org\/10.1007\/s11682-016-9517-6","journal-title":"Brain Imaging Behav"},{"issue":"Suppl 1","key":"9813_CR8","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1111\/j.0013-9580.2004.451009.x","volume":"45","author":"AJ Wilkins","year":"2004","unstructured":"Wilkins AJ, Bonanni P, Porciatti V, Guerrini R (2004) Physiology of human photosensitivity. Epilepsia 45(Suppl 1):7\u201313. https:\/\/doi.org\/10.1111\/j.0013-9580.2004.451009.x","journal-title":"Epilepsia"},{"key":"9813_CR9","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1016\/j.clinph.2010.06.002","volume":"122","author":"D Brazzo","year":"2011","unstructured":"Brazzo D, Di Lorenzo G, Bill P et al (2011) Abnormal visual habituation in pediatric photosensitive epilepsy. Clin Neurophysiol 122:16\u201320. https:\/\/doi.org\/10.1016\/j.clinph.2010.06.002","journal-title":"Clin Neurophysiol"}],"container-title":["Documenta Ophthalmologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10633-020-09813-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10633-020-09813-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10633-020-09813-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,12]],"date-time":"2021-05-12T06:37:58Z","timestamp":1620801478000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10633-020-09813-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,23]]},"references-count":9,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["9813"],"URL":"https:\/\/doi.org\/10.1007\/s10633-020-09813-9","relation":{},"ISSN":["0012-4486","1573-2622"],"issn-type":[{"type":"print","value":"0012-4486"},{"type":"electronic","value":"1573-2622"}],"subject":[],"published":{"date-parts":[[2020,12,23]]},"assertion":[{"value":"29 July 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 December 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 December 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Statement of human rights"}},{"value":"This article does not contain any studies with animals performed by any of the authors.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Statement on the welfare of animals"}},{"value":"Only standard routine procedures were performed, for which the regular institutional policies for consent were followed. No procedure was specifically performed for this case report.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"The parent has consented to the submission of the case report to the journal.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Patient consent"}},{"value":"The authors declare that they have no conflict of interest.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}