{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T01:56:13Z","timestamp":1790560573681,"version":"4.1.0"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T00:00:00Z","timestamp":1790553600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T00:00:00Z","timestamp":1790553600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Doc Ophthalmol"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To establish age-adjusted flicker ERG reference values in premature infants through serial recordings, aiming to characterize retinal functional maturation and support diagnostic interpretation in retinopathy of prematurity screening.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This prospective longitudinal study was conducted between April 2022 and October 2023 across six public neonatal care centers in Rio de Janeiro, Brazil. Premature infants eligible for ROP screening (birth weight \u22641500\u00a0g and\/or gestational age \u226432\u00a0weeks) underwent serial retinal examinations with binocular indirect ophthalmoscopy and flicker electroretinography. Examinations were discontinued at ROP treatment indication or at 42\u00a0weeks postmenstrual age. Flicker ERG recordings were performed using a hand-held RETeval\u00ae device equipped with small-sized Sensor Strip\u2122 skin electrodes. A 30\u00a0cd\u00b7s\/m\n                      <jats:sup>2<\/jats:sup>\n                      white flicker stimulus at 28.3\u00a0Hz was delivered according to a standardized protocol. Recordings were repeated to ensure reproducibility and analyzed according to postmenstrual age (PMA).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of the 199 premature infants, 94 (171 eyes) who never progressed beyond stage 0 ROP were included in the reference analysis. Serial ERG recordings demonstrated a consistent decrease in implicit time and increase in amplitude with advancing PMA. At 32\u201334\u00a0weeks PMA, the upper reference limits (97.5th percentile) were 44.8\u00a0ms and 8.5\u00a0\u00b5V, respectively, compared with 43.5\u00a0ms and 24.9\u00a0\u00b5V at 40\u201342\u00a0weeks PMA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Age-adjusted ERG reference values derived from serial recordings characterize retinal functional maturation in preterm infants, providing a framework for ERG interpretation during routine ROP screening and future studies of retinal development\n                      <jats:bold>.<\/jats:bold>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s10633-026-10152-4","type":"journal-article","created":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T01:24:58Z","timestamp":1790558698000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Electroretinographic assessment of retinal function in preterm infants using the RETeval\u2122 device: a proposal for reference data"],"prefix":"10.1007","author":[{"given":"Viviane","family":"Lanzelotte","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo F.","family":"Damasceno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00e1rbara","family":"Gonet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina do Val F.","family":"Ramos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Gerth-Kahlert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James V. 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