{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T10:37:48Z","timestamp":1761561468292},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2010,9,16]],"date-time":"2010-09-16T00:00:00Z","timestamp":1284595200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2010,9,16]],"date-time":"2010-09-16T00:00:00Z","timestamp":1284595200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Invest New Drugs"],"published-print":{"date-parts":[[2012,4]]},"DOI":"10.1007\/s10637-010-9539-7","type":"journal-article","created":{"date-parts":[[2010,9,15]],"date-time":"2010-09-15T04:57:56Z","timestamp":1284526676000},"page":"688-694","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Methylphenidate in the management of asthenia in breast cancer patients treated with docetaxel: results of a pilot study"],"prefix":"10.1007","volume":"30","author":[{"given":"Juan F.","family":"Cueva","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcos","family":"Calvo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Urbano","family":"Anido","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis","family":"Le\u00f3n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Gallardo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmen","family":"Areses","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beatriz","family":"Bern\u00e1rdez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luc\u00eda","family":"Gayoso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge","family":"Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda","family":"Jes\u00fas Lamas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teresa","family":"Curiel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisca","family":"V\u00e1zquez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonia","family":"Candamio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yolanda","family":"Vidal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco","family":"Javier Bar\u00f3n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafael","family":"L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2010,9,16]]},"reference":[{"key":"9539_CR1","unstructured":"NCCN (2010) Nccn clinical practice guidelines in oncologytm-cancer-related fatigue: http:\/\/www.Nccn.Org\/professionals\/physician_gls\/pdf\/fatigue.Pdf."},{"issue":"9384","key":"9539_CR2","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1016\/S0140-6736(03)14186-4","volume":"362","author":"K Ahlberg","year":"2003","unstructured":"Ahlberg K, Ekman T, Gaston-Johansson F, Mock V (2003) Assessment and management of cancer-related fatigue in adults. Lancet 362(9384):640\u2013650. doi:10.1016\/S0140-6736(03)14186-4","journal-title":"Lancet"},{"issue":"27","key":"9539_CR3","doi-asserted-by":"publisher","first-page":"6613","DOI":"10.1200\/JCO.2005.07.024","volume":"23","author":"MA Andrykowski","year":"2005","unstructured":"Andrykowski MA, Schmidt JE, Salsman JM, Beacham AO, Jacobsen PB (2005) Use of a case definition approach to identify cancer-related fatigue in women undergoing adjuvant therapy for breast cancer. J Clin Oncol 23(27):6613\u20136622. doi:10.1200\/JCO.2005.07.024","journal-title":"J Clin Oncol"},{"issue":"8","key":"9539_CR4","doi-asserted-by":"publisher","first-page":"1117","DOI":"10.1016\/j.ejca.2005.02.016","volume":"41","author":"FK Engels","year":"2005","unstructured":"Engels FK, Verweij J (2005) Docetaxel administration schedule: From fever to tears? A review of randomised studies. Eur J Cancer 41(8):1117\u20131126. doi:10.1016\/j.ejca.2005.02.016","journal-title":"Eur J Cancer"},{"issue":"1","key":"9539_CR5","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1093\/annonc\/mdi018","volume":"16","author":"R Gervais","year":"2005","unstructured":"Gervais R, Ducolone A, Breton JL, Braun D, Lebeau B, Vaylet F, Debieuvre D, Pujol JL, Tredaniel J, Clouet P, Quoix E (2005) Phase ii randomised trial comparing docetaxel given every 3\u00a0weeks with weekly schedule as second-line therapy in patients with advanced non-small-cell lung cancer (nsclc). Ann Oncol 16(1):90\u201396. doi:10.1093\/annonc\/mdi018","journal-title":"Ann Oncol"},{"issue":"9","key":"9539_CR6","doi-asserted-by":"publisher","first-page":"1358","DOI":"10.1093\/annonc\/mdh349","volume":"15","author":"J Tabernero","year":"2004","unstructured":"Tabernero J, Climent MA, Lluch A, Albanell J, Vermorken JB, Barnadas A, Anton A, Laurent C, Mayordomo JI, Estaun N, Losa I, Guillem V, Garcia-Conde J, Tisaire JL, Baselga J (2004) A multicentre, randomised phase ii study of weekly or 3-weekly docetaxel in patients with metastatic breast cancer. Ann Oncol 15(9):1358\u20131365. doi:10.1093\/annonc\/mdh349","journal-title":"Ann Oncol"},{"key":"9539_CR7","unstructured":"NCCN (2010) Nccn clinical practice guidelines in oncologytm-distress management: http:\/\/www.Nccn.Org\/professionals\/physician_gls\/pdf\/distress.Pdf."},{"issue":"1","key":"9539_CR8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1634\/theoncologist.4-1-1","volume":"4","author":"RK Portenoy","year":"1999","unstructured":"Portenoy RK, Itri LM (1999) Cancer-related fatigue: Guidelines for evaluation and management. Oncologist 4(1):1\u201310","journal-title":"Oncologist"},{"issue":"2","key":"9539_CR9","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1016\/S0885-3924(96)00274-6","volume":"13","author":"SB Yellen","year":"1997","unstructured":"Yellen SB, Cella DF, Webster K, Blendowski C, Kaplan E (1997) Measuring fatigue and other anemia-related symptoms with the functional assessment of cancer therapy (fact) measurement system. J Pain Symptom Manage 13(2):63\u201374.","journal-title":"J Pain Symptom Manage"},{"issue":"1","key":"9539_CR10","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1093\/annonc\/mdn537","volume":"20","author":"O Minton","year":"2009","unstructured":"Minton O, Stone P (2009) A systematic review of the scales used for the measurement of cancer-related fatigue (crf). Ann Oncol 20(1):17\u201325. doi:10.1093\/annonc\/mdn537","journal-title":"Ann Oncol"},{"issue":"3","key":"9539_CR11","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1001\/archinte.161.3.411","volume":"161","author":"W Breitbart","year":"2001","unstructured":"Breitbart W, Rosenfeld B, Kaim M, Funesti-Esch J (2001) A randomized, double-blind, placebo-controlled trial of psychostimulants for the treatment of fatigue in ambulatory patients with human immunodeficiency virus disease. Arch Intern Med 161(3):411\u2013420.","journal-title":"Arch Intern Med"},{"issue":"2","key":"9539_CR12","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1136\/jnnp.72.2.179","volume":"72","author":"KW Rammohan","year":"2002","unstructured":"Rammohan KW, Rosenberg JH, Lynn DJ, Blumenfeld AM, Pollak CP, Nagaraja HN (2002) Efficacy and safety of modafinil (provigil) for the treatment of fatigue in multiple sclerosis: A two centre phase 2 study. J Neurol Neurosurg Psychiatry 72(2):179\u2013183","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"8","key":"9539_CR13","doi-asserted-by":"crossref","first-page":"1468","DOI":"10.1212\/WNL.42.8.1468","volume":"42","author":"BG Weinshenker","year":"1992","unstructured":"Weinshenker BG, Penman M, Bass B, Ebers GC, Rice GP (1992) A double-blind, randomized, crossover trial of pemoline in fatigue associated with multiple sclerosis. Neurology 42(8):1468\u20131471","journal-title":"Neurology"},{"issue":"7","key":"9539_CR14","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/S0025-6196(11)64618-1","volume":"75","author":"TD Challman","year":"2000","unstructured":"Challman TD, Lipsky JJ (2000) Methylphenidate: Its pharmacology and uses. Mayo Clin Proc 75(7):711\u2013721","journal-title":"Mayo Clin Proc"},{"issue":"2","key":"9539_CR15","doi-asserted-by":"publisher","first-page":"167 e123","DOI":"10.1016\/j.amjmed.2005.07.047","volume":"119","author":"D Blockmans","year":"2006","unstructured":"Blockmans D, Persoons P, Van Houdenhove B, Bobbaers H (2006) Does methylphenidate reduce the symptoms of chronic fatigue syndrome? Am J Med 119(2):167 e123\u2013130. doi:10.1016\/j.amjmed.2005.07.047","journal-title":"Am J Med"},{"key":"9539_CR16","unstructured":"FDA (2007) Methylphanidate hydrocholire (ritalin\u00ae) - full prescribing information: http:\/\/www.Accessdata.Fda.Gov\/drugsatfda_docs\/label\/2007\/010187s069,018029s040,021284s011lbl.Pdf."},{"issue":"23","key":"9539_CR17","doi-asserted-by":"publisher","first-page":"4795","DOI":"10.1200\/JCO.2004.04.128","volume":"22","author":"RK Mulhern","year":"2004","unstructured":"Mulhern RK, Khan RB, Kaplan S, Helton S, Christensen R, Bonner M, Brown R, Xiong X, Wu S, Gururangan S, Reddick WE (2004) Short-term efficacy of methylphenidate: A randomized, double-blind, placebo-controlled trial among survivors of childhood cancer. J Clin Oncol 22(23):4795\u20134803. doi:10.1200\/JCO.2004.04.128","journal-title":"J Clin Oncol"},{"issue":"9","key":"9539_CR18","first-page":"455","volume":"28","author":"F Fernandez","year":"1987","unstructured":"Fernandez F, Adams F, Holmes VF, Levy JK, Neidhart M (1987) Methylphenidate for depressive disorders in cancer patients. An alternative to standard antidepressants Psychosomatics 28(9):455\u2013461","journal-title":"An alternative to standard antidepressants. Psychosomatics"},{"issue":"3","key":"9539_CR19","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1016\/S0193-953X(05)70304-X","volume":"19","author":"PS Masand","year":"1996","unstructured":"Masand PS, Tesar GE (1996) Use of stimulants in the medically ill. Psychiatr Clin North Am 19(3):515\u2013547","journal-title":"Psychiatr Clin North Am"},{"issue":"1","key":"9539_CR20","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1200\/JCO.20.1.335","volume":"20","author":"M Rozans","year":"2002","unstructured":"Rozans M, Dreisbach A, Lertora JJ, Kahn MJ (2002) Palliative uses of methylphenidate in patients with cancer: A review. J Clin Oncol 20(1):335\u2013339","journal-title":"J Clin Oncol"},{"issue":"23","key":"9539_CR21","doi-asserted-by":"publisher","first-page":"4439","DOI":"10.1200\/JCO.2003.06.156","volume":"21","author":"E Bruera","year":"2003","unstructured":"Bruera E, Driver L, Barnes EA, Willey J, Shen L, Palmer JL, Escalante C (2003) Patient-controlled methylphenidate for the management of fatigue in patients with advanced cancer: A preliminary report. J Clin Oncol 21(23):4439\u20134443. doi:10.1200\/JCO.2003.06.156JCO.2003.06.156","journal-title":"J Clin Oncol"},{"issue":"3","key":"9539_CR22","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1177\/104990910101800310","volume":"18","author":"N Sarhill","year":"2001","unstructured":"Sarhill N, Walsh D, Nelson KA, Homsi J, LeGrand S, Davis MP (2001) Methylphenidate for fatigue in advanced cancer: A prospective open-label pilot study. Am J Hosp Palliat Care 18(3):187\u2013192","journal-title":"Am J Hosp Palliat Care"},{"issue":"7","key":"9539_CR23","doi-asserted-by":"publisher","first-page":"E85","DOI":"10.1188\/02.ONF.E85-E90","volume":"29","author":"AL Schwartz","year":"2002","unstructured":"Schwartz AL, Thompson JA, Masood N (2002) Interferon-induced fatigue in patients with melanoma: A pilot study of exercise and methylphenidate. Oncol Nurs Forum 29(7):E85\u201390. doi:10.1188\/02.ONF.E85-E90","journal-title":"Oncol Nurs Forum"},{"issue":"1","key":"9539_CR24","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1177\/104990910602300106","volume":"23","author":"A Sood","year":"2006","unstructured":"Sood A, Barton DL, Loprinzi CL (2006) Use of methylphenidate in patients with cancer. Am J Hosp Palliat Care 23(1):35\u201340","journal-title":"Am J Hosp Palliat Care"},{"issue":"13","key":"9539_CR25","doi-asserted-by":"publisher","first-page":"2073","DOI":"10.1200\/JCO.2005.02.8506","volume":"24","author":"E Bruera","year":"2006","unstructured":"Bruera E, Valero V, Driver L, Shen L, Willey J, Zhang T, Palmer JL (2006) Patient-controlled methylphenidate for cancer fatigue: A double-blind, randomized, placebo-controlled trial. J Clin Oncol 24(13):2073\u20132078. doi:10.1200\/JCO.2005.02.8506","journal-title":"J Clin Oncol"},{"issue":"5","key":"9539_CR26","doi-asserted-by":"publisher","first-page":"650","DOI":"10.1016\/j.jpainsymman.2009.03.011","volume":"38","author":"EE Lower","year":"2009","unstructured":"Lower EE, Fleishman S, Cooper A, Zeldis J, Faleck H, Yu Z, Manning D (2009) Efficacy of dexmethylphenidate for the treatment of fatigue after cancer chemotherapy: A randomized clinical trial. J Pain Symptom Manage 38(5):650\u2013662. doi:10.1016\/j.jpainsymman.2009.03.011","journal-title":"J Pain Symptom Manage"},{"issue":"6","key":"9539_CR27","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1007\/s00520-007-0341-9","volume":"16","author":"HG Mar Fan","year":"2008","unstructured":"Mar Fan HG, Clemons M, Xu W, Chemerynsky I, Breunis H, Braganza S, Tannock IF (2008) A randomised, placebo-controlled, double-blind trial of the effects of d-methylphenidate on fatigue and cognitive dysfunction in women undergoing adjuvant chemotherapy for breast cancer. Support Care Cancer 16(6):577\u2013583. doi:10.1007\/s00520-007-0341-9","journal-title":"Support Care Cancer"},{"issue":"3","key":"9539_CR28","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1007\/s00520-005-0857-9","volume":"14","author":"A Hanna","year":"2006","unstructured":"Hanna A, Sledge G, Mayer ML, Hanna N, Einhorn L, Monahan P, Daggy J, Bhatia S (2006) A phase ii study of methylphenidate for the treatment of fatigue. Support Care Cancer 14(3):210\u2013215. doi:10.1007\/s00520-005-0857-9","journal-title":"Support Care Cancer"},{"issue":"16","key":"9539_CR29","doi-asserted-by":"publisher","first-page":"1155","DOI":"10.1093\/jnci\/djn250","volume":"100","author":"O Minton","year":"2008","unstructured":"Minton O, Richardson A, Sharpe M, Hotopf M, Stone P (2008) A systematic review and meta-analysis of the pharmacological treatment of cancer-related fatigue. J Natl Cancer Inst 100(16):1155\u20131166. doi:10.1093\/jnci\/djn250","journal-title":"J Natl Cancer Inst"},{"issue":"6","key":"9539_CR30","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1111\/j.1600-0447.1983.tb09716.x","volume":"67","author":"AS Zigmond","year":"1983","unstructured":"Zigmond AS, Snaith RP (1983) The hospital anxiety and depression scale. Acta Psychiatr Scand 67(6):361\u2013370","journal-title":"Acta Psychiatr Scand"}],"container-title":["Investigational New Drugs"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10637-010-9539-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10637-010-9539-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10637-010-9539-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10637-010-9539-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,11]],"date-time":"2023-03-11T18:18:39Z","timestamp":1678558719000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10637-010-9539-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,9,16]]},"references-count":30,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,4]]}},"alternative-id":["9539"],"URL":"https:\/\/doi.org\/10.1007\/s10637-010-9539-7","relation":{},"ISSN":["0167-6997","1573-0646"],"issn-type":[{"value":"0167-6997","type":"print"},{"value":"1573-0646","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,9,16]]},"assertion":[{"value":"10 June 2010","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 September 2010","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 September 2010","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}