{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T01:43:26Z","timestamp":1777513406815,"version":"3.51.4"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2016,9,20]],"date-time":"2016-09-20T00:00:00Z","timestamp":1474329600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Bayer CropScience AG (Monheim, Germany)"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ecotoxicology"],"published-print":{"date-parts":[[2016,11]]},"DOI":"10.1007\/s10646-016-1723-x","type":"journal-article","created":{"date-parts":[[2016,9,20]],"date-time":"2016-09-20T08:52:15Z","timestamp":1474361535000},"page":"1691-1701","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":44,"title":["Large-scale monitoring of effects of clothianidin-dressed oilseed rape seeds on pollinating insects in northern Germany: residues of clothianidin in pollen, nectar and honey"],"prefix":"10.1007","volume":"25","author":[{"given":"Daniel","family":"Rolke","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markus","family":"Persigehl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Britta","family":"Peters","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guido","family":"Sterk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6874-4730","authenticated-orcid":false,"given":"Wolfgang","family":"Blenau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,9,20]]},"reference":[{"key":"1723_CR1","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1007\/s13592-012-0134-0","volume":"43","author":"LP Belzunces","year":"2012","unstructured":"Belzunces LP, Tchamitchian S, Brunet JL (2012) Neural effects of insecticides in the honey bee. Apidologie 43:348\u2013370","journal-title":"Apidologie"},{"key":"1723_CR2","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1007\/s10646-012-0863-x","volume":"21","author":"T Blacqui\u00e8re","year":"2012","unstructured":"Blacqui\u00e8re T, Smagghe G, Vangestel CAM, Mommaerts V (2012) Neonicotinoids in bees: a review on concentrations, side-effects and risk assessment. Ecotoxicology 21:973\u2013992","journal-title":"Ecotoxicology"},{"key":"1723_CR3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3896\/IBRA.1.52.4.03","volume":"52","author":"NL Carreck","year":"2013","unstructured":"Carreck NL, Andree M, Brent CS, Cox-Foster D, Dade HA, Ellis J, Hatjina F, vanEngelsdorp D (2013) Standard methods for Apis mellifera anatomy and dissection. J Apicult Res 52:1\u201339","journal-title":"J Apicult Res"},{"key":"1723_CR4","doi-asserted-by":"crossref","first-page":"607","DOI":"10.3896\/IBRA.1.53.5.08","volume":"53","author":"NL Carreck","year":"2014","unstructured":"Carreck NL, Ratnieks FLW (2014) The dose makes the poison: have \u201cfield realistic\u201d rates of exposure of bees to neonicotinoid insecticides been overestimated in laboratory studies? J Apicult Res 53:607\u2013614","journal-title":"J Apicult Res"},{"key":"1723_CR5","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1126\/science.1224618","volume":"337","author":"JE Cresswell","year":"2012","unstructured":"Cresswell JE, Thompson HM (2012) Comment on \u201ca common pesticide decreases foraging success and survival in honey bees\u201d. Science 337:1453","journal-title":"Science"},{"key":"1723_CR6","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1603\/0022-0493(2007)100[765:ETCSCH]2.0.CO;2","volume":"100","author":"GC Cutler","year":"2007","unstructured":"Cutler GC, Scott-Dupree CD (2007) Exposure to clothianidin seed-treated canola has no long-term impact on honey bees. J Econ Entomol 100:765\u2013772","journal-title":"J Econ Entomol"},{"key":"1723_CR7","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.1007\/s10646-014-1340-5","volume":"23","author":"GC Cutler","year":"2014","unstructured":"Cutler GC, Scott-Dupree CD (2014) A field study examining the effects of exposure to neonicotinoid seed-treated corn on commercial bumble bee colonies. Ecotoxicology 23:1755\u20131763","journal-title":"Ecotoxicology"},{"key":"1723_CR8","doi-asserted-by":"crossref","first-page":"e652","DOI":"10.7717\/peerj.652","volume":"2","author":"GC Cutler","year":"2014","unstructured":"Cutler GC, Scott-Dupree CD, Sultan M, McFarlane AD, Brewer L (2014) A large-scale field study examining effects of exposure to clothianidin seed-treated canola on honey bee colony health, development, and overwintering success. PeerJ 2:e652","journal-title":"PeerJ"},{"key":"1723_CR9","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1002\/ps.1616","volume":"64","author":"A Elbert","year":"2008","unstructured":"Elbert A, Haas M, Springer B, Thielert W, Nauen R (2008) Applied aspects of neonicotinoid uses in crop protection. Pest Manag Sci 64:1099\u20131105","journal-title":"Pest Manag Sci"},{"key":"1723_CR10","unstructured":"EN15662:2008 (2009) Foods of plant origin \u2013 Determination of pesticide residues using GC\/MS and\/or LC-MS\/MS following acetonitrile extraction\/partitioning and clean-up by dispersive SPE \u2013 QuEChERS-Method. German version"},{"key":"1723_CR11","unstructured":"European Commission (2013) Commission Implementing Regulation (EU) No 485\/2013 of 24 May 2013 amending Implementing Regulation (EU) No 540\/2011, as regards the conditions of approval of the active substances clothianidin, thiamethoxamand imidacloprid, and prohibiting the use and sale of seeds treatedwith plant protection products containing those active substances. OJ L 139:12\u201326"},{"key":"1723_CR12","unstructured":"European Commission (2015) EU pesticide database. http:\/\/ec.europa.eu\/food\/plant\/pesticides\/eu\u2013pesticides-database\/public\/?event=download.MRL. Accessed 4 Sep 2015"},{"key":"1723_CR13","unstructured":"EUROSTAT (2016) European Statistics. http:\/\/ec.europa.eu\/eurostat\/data\/database . Accessed 18 Apr 2016"},{"key":"1723_CR14","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1051\/apido\/2010014","volume":"41","author":"E Genersch","year":"2010","unstructured":"Genersch E, von der Ohe W, Kaatz H, Schroeder A, Otten C, B\u00fcchler R, Berg S, Ritter W, M\u00fchlen W, Gisder S, Meixner M, Liebig G, Rosenkranz P (2010) The German bee monitoring project: a long term study to understand periodically high winter losses of honey bee colonies. Apidologie 41:332\u2013352","journal-title":"Apidologie"},{"key":"1723_CR15","doi-asserted-by":"crossref","first-page":"20140558","DOI":"10.1098\/rspb.2014.0558","volume":"281","author":"HC Godfray","year":"2014","unstructured":"Godfray HC, Blacqui\u00e8re T, Field LM, Hails RS, Petrokofsky G, Potts SG, Raine NE, Vanbergen AJ, McLean AR (2014) A restatement of the natural science evidence base concerning neonicotinoid insecticides and insect pollinators. Proc Biol Sci 281:20140558","journal-title":"Proc Biol Sci"},{"key":"1723_CR16","doi-asserted-by":"crossref","first-page":"20151821","DOI":"10.1098\/rspb.2015.1821","volume":"282","author":"HC Godfray","year":"2015","unstructured":"Godfray HC, Blacqui\u00e8re T, Field LM, Hails RS, Potts SG, Raine NE, Vanbergen AJ, McLean AR (2015) A restatement of recent advances in the natural science evidence base concerning neonicotinoid insecticides and insect pollinators. Proc Biol Sci 282:20151821","journal-title":"Proc Biol Sci"},{"key":"1723_CR17","doi-asserted-by":"crossref","first-page":"1255957","DOI":"10.1126\/science.1255957","volume":"347","author":"D Goulson","year":"2015","unstructured":"Goulson D, Nicholls E, Bot\u00edas C, Rotheray EL (2015) Bee declines driven by combined stress from parasites, pesticides, and lack of flowers. Science 347:1255957","journal-title":"Science"},{"key":"1723_CR18","first-page":"142","volume":"4","author":"D Guez","year":"2013","unstructured":"Guez D (2013) Henry et al. (2012) homing failure formula, assumptions, and basic mathematics: a comment. Front Physiol 4:142","journal-title":"Front Physiol"},{"key":"1723_CR19","doi-asserted-by":"crossref","unstructured":"Heimbach F, Russ A, Schimmer M, Born K (2016) Large-scale monitoring of effects of clothianidin dressed oilseed rape seeds on pollinating insects in northern Germany: implementation of the monitoring project and its representativeness. Ecotoxicology","DOI":"10.1007\/s10646-016-1724-9"},{"key":"1723_CR37","doi-asserted-by":"crossref","unstructured":"Jeschke P, Nauen R, Beck ME (2013) Nicotinic acetylcholine receptor agonists: a milestone for modern crop protection. Angew Chem Int Ed Engl 52:9464\u20139485","DOI":"10.1002\/anie.201302550"},{"key":"1723_CR20","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1146\/annurev-ento-011613-162005","volume":"60","author":"RM Johnson","year":"2015","unstructured":"Johnson RM (2015) Honey bee toxicology. Annu Rev Entomol 60:415\u2013434","journal-title":"Annu Rev Entomol"},{"key":"1723_CR21","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1098\/rspb.2006.3721","volume":"274","author":"AM Klein","year":"2007","unstructured":"Klein AM, Vaissi\u00e8re BE, Cane JH, Steffan-Dewenter I, Cunningham SA, Kremen C, Tscharntke T (2007) Importance of pollinators in changing landscapes for world crops. Proc Biol Sci 274:303\u2013313","journal-title":"Proc Biol Sci"},{"key":"1723_CR22","first-page":"239","volume":"19","author":"SJ Lehotay","year":"2006","unstructured":"Lehotay SJ (2006) Quick, easy, cheap, effective, rugged, and safe approach for determining pesticide residues. Method Biotechnol 19:239\u2013261","journal-title":"Method Biotechnol"},{"key":"1723_CR23","doi-asserted-by":"crossref","unstructured":"Peters B, Gao Z, Zumkier U (2016) Large-scale monitoring of effects of clothianidin dressed OSR seeds on pollinating insects in northern Germany: effects on red mason bees (Osmia bicornis). Ecotoxicology","DOI":"10.1007\/s10646-016-1729-4"},{"key":"1723_CR36","doi-asserted-by":"crossref","unstructured":"Pilling E, Campbell P, Coulson M, Ruddle N, Tornier I (2013) A four-year field program investigating long-term effects of repeated exposure of honey bee colonies to flowering crops treated with thiamethoxam. PLoS One 8:e77193","DOI":"10.1371\/journal.pone.0077193"},{"key":"1723_CR24","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1007\/s11356-014-3471-x","volume":"22","author":"LW Pisa","year":"2015","unstructured":"Pisa LW, Amaral-Rogers V, Belzunces LP, Bonmatin JM, Downs CA, Goulson D, Kreutzweiser DP, Krupke C, Liess M, McField M, Morrissey CA, Noome DA, Settele J, Simon-Delso N, Stark JD, Van der Sluijs JP, Van Dyck H, Wiemers M (2015) Effects of neonicotinoids and fipronil on non-target invertebrates. Environ Sci Pollut Res Int 22:68\u2013102","journal-title":"Environ Sci Pollut Res Int"},{"key":"1723_CR25","first-page":"115","volume":"56","author":"K Pohorecka","year":"2012","unstructured":"Pohorecka K, Skubida P, Miszczak A, Semkiw P, Sikorski P, Zagibaj\u0142o K, Teper D, Ko\u0142towski Z, Skubida M, Zdanska D, Bober A (2012) Residues of neonicotinoid insecticides in bee collected plant materials from oilseed rape crops and their effects on bee colonies. J Apic Sci 56:115\u2013134","journal-title":"J Apic Sci"},{"key":"1723_CR26","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.tree.2010.01.007","volume":"25","author":"SG Potts","year":"2010","unstructured":"Potts SG, Biesmeijer JC, Kremen C, Neumann P, Schweiger O, Kunin WE (2010) Global pollinator declines: trends, impacts and drivers. Trends Ecol Evol 25:345\u2013353","journal-title":"Trends Ecol Evol"},{"key":"1723_CR27","doi-asserted-by":"crossref","unstructured":"Rolke D, Fuchs S, Gr\u00fcnewald B, Gao Z, Blenau W (2016) Large-scale monitoring of effects of clothianidin dressed oilseed rape seeds on pollinating insects in northern Germany: Effects on honey bees (Apis mellifera). Ecotoxicology","DOI":"10.1007\/s10646-016-1725-8"},{"key":"1723_CR28","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1038\/nature14420","volume":"521","author":"M Rundl\u00f6f","year":"2015","unstructured":"Rundl\u00f6f M, Andersson GK, Bommarco R, Fries I, Hederstr\u00f6m V, Herbertsson L, Jonsson O, Klatt BK, Pedersen TR, Yourstone J, Smith HG (2015) Seed coating with a neonicotinoid insecticide negatively affects wild bees. Nature 521:77\u201380","journal-title":"Nature"},{"key":"1723_CR29","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1126\/science.1259159","volume":"346","author":"F S\u00e1nchez-Bayo","year":"2014","unstructured":"S\u00e1nchez-Bayo F (2014) Environmental science. The trouble with neonicotinoids. Science 346:806\u2013807","journal-title":"Science"},{"key":"1723_CR30","first-page":"26","volume":"56","author":"R Schmuck","year":"2003","unstructured":"Schmuck R, Keppler J (2003) Clothianidin \u2013 Ecotoxicological profile and risk assessment. Bayer-Pflanzenschutznachrichten 56:26-58","journal-title":"Bayer-Pflanzenschutznachrichten"},{"key":"1723_CR31","doi-asserted-by":"crossref","unstructured":"Schmuck R, Lewis G (2016) Review of field and monitoring studies investigating the role of nitro-substituted neonicotinoid insecticides in the reported losses of honey bee colonies (Apis mellifera). Ecotoxicology","DOI":"10.1007\/s10646-016-1734-7"},{"key":"1723_CR32","doi-asserted-by":"crossref","unstructured":"Sterk G, Peters B, Gao Z, Zumkier U (2016) Large-scale monitoring of effects of clothianidin dressed OSR seeds on pollinating insects in northern Germany: Effects on large earth bumble bees (Bombus terrestris). Ecotoxicology","DOI":"10.1007\/s10646-016-1730-y"},{"key":"1723_CR33","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.1002\/etc.2988","volume":"34","author":"H Thompson","year":"2015","unstructured":"Thompson H, Miles M (2015) In response: the challenge of implementing a sustainable and highly sophisticated risk-assessment scheme, able to address the realistic potential hazards as well as the needs of our pollinators\u2014An industry view on the key challenges and guidance. Environ Toxicol Chem 34:1456\u20131458","journal-title":"Environ Toxicol Chem"},{"key":"1723_CR34","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1146\/annurev.pharmtox.45.120403.095930","volume":"45","author":"M Tomizawa","year":"2005","unstructured":"Tomizawa M, Casida JE (2005) Neonicotinoid insecticide toxicology: mechanisms of selective action. Annu Rev Pharmacol Toxicol 45:247\u2013268","journal-title":"Annu Rev Pharmacol Toxicol"},{"key":"1723_CR35","volume-title":"The Biology of the Honey Bee","author":"ML Winston","year":"1987","unstructured":"Winston ML (1987) The Biology of the Honey Bee, 1st edn. Harvard University Press, Cambridge, MA","edition":"1st edn."}],"container-title":["Ecotoxicology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10646-016-1723-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10646-016-1723-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10646-016-1723-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,24]],"date-time":"2017-06-24T19:14:36Z","timestamp":1498331676000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10646-016-1723-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9,20]]},"references-count":37,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2016,11]]}},"alternative-id":["1723"],"URL":"https:\/\/doi.org\/10.1007\/s10646-016-1723-x","relation":{},"ISSN":["0963-9292","1573-3017"],"issn-type":[{"value":"0963-9292","type":"print"},{"value":"1573-3017","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,9,20]]}}}