{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T11:45:10Z","timestamp":1785843910901,"version":"3.56.0"},"reference-count":101,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T00:00:00Z","timestamp":1777334400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T00:00:00Z","timestamp":1777334400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ecotoxicology"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1007\/s10646-026-03096-7","type":"journal-article","created":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T06:36:13Z","timestamp":1777358173000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Cytogenetic bioassays in model plants to evaluate the environmental toxicity of pharmaceutical residues"],"prefix":"10.1007","volume":"35","author":[{"given":"Seir Antonio Salazar","family":"Mercado","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reiner Ricardo Alvernia","family":"Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,4,28]]},"reference":[{"key":"3096_CR1","doi-asserted-by":"publisher","first-page":"112727","DOI":"10.1016\/j.ecoenv.2021.112727","volume":"225","author":"KS Alaoui","year":"2021","unstructured":"Alaoui KS, Tychon B, Joachim S, Geffard A, Nott K, Ronkart S, Porcher J, Beaudouin R, Robert C, Fauconnier M, Saive M (2021) Toxic effects of a mixture of five pharmaceutical drugs assessed using Fontinalis antipyretica Hedw. Ecotoxicol Environ Saf 225:112727. https:\/\/doi.org\/10.1016\/j.ecoenv.2021.112727","journal-title":"Ecotoxicol Environ Saf"},{"key":"3096_CR3","doi-asserted-by":"publisher","first-page":"503654","DOI":"10.1016\/j.mrgentox.2023.503654","volume":"889","author":"C Alias","year":"2023","unstructured":"Alias C, Feretti D, Viola GV, Zerbini I, Bisceglie F, Pelosi G, Zani C, Buschini A, Carcelli M, Rogolino D, Restivo FM, Degola F (2023) Allium cepa tests: A plant-based tool for the early evaluation of toxicity and genotoxicity of newly synthetized antifungal molecules. Mutat Research\/Genetic Toxicol Environ Mutagen 889:503654. https:\/\/doi.org\/10.1016\/j.mrgentox.2023.503654","journal-title":"Mutat Research\/Genetic Toxicol Environ Mutagen"},{"key":"3096_CR2","doi-asserted-by":"publisher","unstructured":"Alketbi M, Ali R, Mutery AAL (2025) The impact of contaminated water with pharmaceutical hazards on the Vicia faba plant cell\u2019s components and mitosis behavior. Beni-Suef Univ J Basic Appl Sci 14(1). https:\/\/doi.org\/10.1186\/s43088-025-00628-8","DOI":"10.1186\/s43088-025-00628-8"},{"key":"3096_CR5","doi-asserted-by":"publisher","first-page":"1448731","DOI":"10.3389\/fphar.2024.1448731","volume":"15","author":"G Al-Naqeb","year":"2024","unstructured":"Al-Naqeb G, Kalmpourtzidou A, Giampieri F, De Giuseppe R, Cena H (2024) Genotoxic and antigenotoxic medicinal plant extracts and their main phytochemicals: A review. Front Pharmacol 15:1448731. https:\/\/doi.org\/10.3389\/fphar.2024.1448731","journal-title":"Front Pharmacol"},{"key":"3096_CR4","doi-asserted-by":"publisher","first-page":"S13","DOI":"10.1016\/j.farma.2023.09.010","volume":"48","author":"M Alzola-Andr\u00e9s","year":"2024","unstructured":"Alzola-Andr\u00e9s M, Domingo-Echaburu S, Nogales-Garcia M, Palacios-Zabalza I, Urrutia-Losada A, Arteche-Elguizabal L, De Torre Querejazu AL, Basterra AQ, Orive G, Lertxundi U (2024) El impacto ambiental de los medicamentos: una mirada desde la farmacia hospitalaria. Farm Hosp 48:S13\u2013S20. https:\/\/doi.org\/10.1016\/j.farma.2023.09.010","journal-title":"Farm Hosp"},{"key":"3096_CR6","doi-asserted-by":"publisher","unstructured":"Animasaun DA, Adedibu PA, Afolabi SO, Abdulkareem KA, Ibrahim S, Krishnamurthy R (2024) Hazard assessment and cytogenotoxic effect of different concentrations of mercury chloride sterilant using the Allium cepa assay. Discover Toxicol 1(1). https:\/\/doi.org\/10.1007\/s44339-024-00002-w","DOI":"10.1007\/s44339-024-00002-w"},{"key":"3096_CR7","doi-asserted-by":"publisher","unstructured":"Annakkaya N, \u00c7avu\u015fo\u011flu K, Yal\u00e7in E, \u00d6zkan B (2025) Investigation of in-vivo and in-silico toxicity induced by environmental drug contamination in a non-target organism. Sci Rep 15(1). https:\/\/doi.org\/10.1038\/s41598-025-07417-4","DOI":"10.1038\/s41598-025-07417-4"},{"key":"3096_CR8","doi-asserted-by":"publisher","DOI":"10.1039\/d4ma01122h","author":"KHH Aziz","year":"2025","unstructured":"Aziz KHH, Mustafa FS, Karim MAH, Hama S (2025) Pharmaceutical pollution in the aquatic environment: advanced oxidation processes as efficient treatment approaches: a review. Mater Adv. https:\/\/doi.org\/10.1039\/d4ma01122h","journal-title":"Mater Adv"},{"issue":"3","key":"3096_CR9","doi-asserted-by":"publisher","first-page":"e0226315","DOI":"10.1371\/journal.pone.0226315","volume":"15","author":"MF Azzazy","year":"2020","unstructured":"Azzazy MF (2020) Plant bioindicators of pollution in Sadat City, Western Nile Delta. Egypt PLoS ONE 15(3):e0226315. https:\/\/doi.org\/10.1371\/journal.pone.0226315","journal-title":"Egypt PLoS ONE"},{"issue":"13","key":"3096_CR10","doi-asserted-by":"publisher","first-page":"1626","DOI":"10.3390\/plants11131626","volume":"11","author":"Z Badar","year":"2022","unstructured":"Badar Z, Shanableh A, El-Keblawy A, Mosa KA, Semerjian L, Mutery AA, Hussain MI, Bhattacharjee S, Tsombou FM, Ayyaril SS, Ahmady IM, Elnaggar A, Mousa M, Semreen MH (2022) Assessment of Uptake, Accumulation and Degradation of Paracetamol in Spinach (Spinacia oleracea L.) under Controlled Laboratory Conditions. Plants 11(13):1626. https:\/\/doi.org\/10.3390\/plants11131626","journal-title":"Plants"},{"key":"3096_CR11","doi-asserted-by":"publisher","unstructured":"Bajaj M, Maheshwari A, Agrawal R, Monika M, Prity P, Meena S, Tripathi A, Thakur K, Mangesh M (2023) Cytotoxic and Genotoxic Effects of the Antibiotic Streptomycin on Root Meristem Cells of Allium cepa L. Int J Pharm Sci Rev Res 83(2). https:\/\/doi.org\/10.47583\/ijpsrr.2023.v83i02.010","DOI":"10.47583\/ijpsrr.2023.v83i02.010"},{"key":"3096_CR12","doi-asserted-by":"publisher","first-page":"103377","DOI":"10.1016\/j.etap.2020.103377","volume":"77","author":"I Barbosa","year":"2020","unstructured":"Barbosa I, Pizarro I, Freitas R, Nunes B (2020) Antioxidative and neurotoxicity effects of acute and chronic exposure of the estuarine polychaete Hediste diversicolor to paracetamol. Environ Toxicol Pharmacol 77:103377. https:\/\/doi.org\/10.1016\/j.etap.2020.103377","journal-title":"Environ Toxicol Pharmacol"},{"key":"3096_CR13","unstructured":"Barros DGDC (2023) Toxicidade do filtro solar benzofenona-3 em concentra\u00e7\u00f5es ambientais relevantes a plantas: subs\u00eddios para determina\u00e7\u00e3o do risco ambiental (Bachelor\u2019s thesis, Universidade Tecnol\u00f3gica Federal do Paran\u00e1)"},{"key":"3096_CR14","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2024\/8985402","volume":"2024","author":"BB Belay","year":"2024","unstructured":"Belay BB, Taye AE (2024) Potential Toxic Metal Concentration and Risk Assessment in Agricultural Soil and Lentil Crop (Lens culinaris Medik) in Dawunt Woreda, Northwest Wollo, Ethiopia. J Toxicol 2024:1\u201314. https:\/\/doi.org\/10.1155\/2024\/8985402","journal-title":"J Toxicol"},{"key":"3096_CR15","doi-asserted-by":"publisher","first-page":"113936","DOI":"10.1016\/j.jenvman.2021.113936","volume":"302","author":"R Biczak","year":"2021","unstructured":"Biczak R, Paw\u0142owska B (2021) Reaction of spring barley seedlings and H. incongruens crustaceans to the presence of acetylsalicylic acid in soil. J Environ Manage 302:113936. https:\/\/doi.org\/10.1016\/j.jenvman.2021.113936","journal-title":"J Environ Manage"},{"key":"3096_CR16","unstructured":"Bonciu E (2023) Clastogenic potential of some chemicals used in agriculture monitored through the Allium assay"},{"issue":"3","key":"3096_CR17","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1080\/00087114.2018.1503496","volume":"71","author":"E Bonciu","year":"2018","unstructured":"Bonciu E, Firbas P, Fontanetti CS, Wusheng J, Pancotto K, Rank J, Barb\u00e9rio A (2018) An evaluation for the standardization of the Allium cepa test as cytotoxicity and genotoxicity assay. Caryologia 71(3):191\u2013209. https:\/\/doi.org\/10.1080\/00087114.2018.1503496","journal-title":"Caryologia"},{"issue":"1","key":"3096_CR18","doi-asserted-by":"publisher","first-page":"59","DOI":"10.4995\/ia.2021.13660","volume":"25","author":"L Castro-Pastrana","year":"2021","unstructured":"Castro-Pastrana L, Cerro-L\u00f3pez M, Toledo-Wall M, G\u00f3mez-Oliv\u00e1n L, Sald\u00edvar-Santiago M (2021) An\u00e1lisis de F\u00e1rmacos en Aguas Residuales de Tres Hospitales de la Ciudad de Puebla, M\u00e9xico. Ingenier\u00eda Del Agua 25(1):59\u201373","journal-title":"Ingenier\u00eda Del Agua"},{"key":"3096_CR19","doi-asserted-by":"publisher","first-page":"116610","DOI":"10.1016\/j.watres.2020.116610","volume":"189","author":"O Celis-Hernandez","year":"2020","unstructured":"Celis-Hernandez O, Cundy AB, Croudace IW, Ward RD, Busquets R, Wilkinson JL (2020) Assessing the role of the estuarine filter for emerging contaminants: pharmaceuticals, perfluoroalkyl compounds and plasticisers in sediment cores from two contrasting systems in the southern U.K. Water Res 189:116610. https:\/\/doi.org\/10.1016\/j.watres.2020.116610","journal-title":"Water Res"},{"key":"3096_CR20","unstructured":"Chavez CA, Vidoz ML, Medina RD, Mignolli F (2023) Respuestas de las plantas de tomate (Solanum lycopersicum L.) al estr\u00e9s oxidativo durante eventos de inundaci\u00f3n y post-inundaci\u00f3n. https:\/\/agris.fao.org\/search\/en\/providers\/124983\/records\/67050d43b1dfe472e14503f8"},{"key":"3096_CR22","unstructured":"Cruz FA, Cortes LDG, Matamoros JR (2025) El papel de los bioindicadores en la detecci\u00f3n de contaminantes ambientales en los h\u00e1bitats naturales y urbanos. Revista SPINOR, (60)"},{"key":"3096_CR23","doi-asserted-by":"publisher","unstructured":"Cruz-Inca K, Suna-Alag\u00f3n L, Iannacone JA (2025) Toxicidad del glifosato en guisantes (Pisum sativum) en suelos franco arenosos con un consorcio bacteriano. Agronom\u00eda Mesoamericana 63041. https:\/\/doi.org\/10.15517\/am.2025.63041","DOI":"10.15517\/am.2025.63041"},{"key":"3096_CR24","doi-asserted-by":"crossref","unstructured":"Cruz VH, de Almeida Moreira BR, Val\u00e9rio TS, Frias YA, da Silva VL, de Morais EB, Lopes PRM (2024) Green Manure and Microbial Inoculation. An Approach for Biocatalytic Phytoremediation of Tebuthiuron in Agricultural Soil","DOI":"10.20944\/preprints202409.1124.v1"},{"issue":"1","key":"3096_CR21","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1080\/12269328.2011.10541328","volume":"14","author":"DM Cuong","year":"2011","unstructured":"Cuong DM, Kim K, Toan TQ, Phu TD (2011) Review: Source, Fate, Toxicological Effect and Removal Technology of Pharmaceuticals in the Environment. Geosystem Eng 14(1):35\u201342. https:\/\/doi.org\/10.1080\/12269328.2011.10541328","journal-title":"Geosystem Eng"},{"key":"3096_CR25","doi-asserted-by":"publisher","first-page":"111851","DOI":"10.1016\/j.mrfmmm.2024.111851","volume":"828","author":"R Das","year":"2024","unstructured":"Das R, Ray S (2024) Allium cepa tests: Exploring bleomycin induced cyto genotoxicity and altered cell cycle kinetics in root tips meristematic cells. Mutat Research\/Fundamental Mol Mech Mutagen 828:111851. https:\/\/doi.org\/10.1016\/j.mrfmmm.2024.111851","journal-title":"Mutat Research\/Fundamental Mol Mech Mutagen"},{"key":"3096_CR26","unstructured":"Diaz TA, Reyes ER, Gonz\u00e1lez JC, Carrasco JM (2021) Estr\u00e9s oxidativo, terapia antioxidante y c\u00e1ncer. Revista Cubana de Oncolog\u00eda, 19(2):e_117 https:\/\/revoncologia.sld.cu\/index.php\/onc\/article\/view\/117"},{"issue":"4","key":"3096_CR27","doi-asserted-by":"publisher","first-page":"3633","DOI":"10.1007\/s13762-023-05238-4","volume":"21","author":"J Drzyma\u0142a","year":"2023","unstructured":"Drzyma\u0142a J, Kalka J (2023) Assessment of genotoxicity, mutagenicity, and cytotoxicity of diclofenac and sulfamethoxazole at environmental concentrations on Vicia faba. Int J Environ Sci Technol 21(4):3633\u20133648. https:\/\/doi.org\/10.1007\/s13762-023-05238-4","journal-title":"Int J Environ Sci Technol"},{"issue":"2","key":"3096_CR28","first-page":"105","volume":"194","author":"R Dzingelevi\u010dien\u0117","year":"2022","unstructured":"Dzingelevi\u010dien\u0117 R, Pashaei R, Abbasi Sy, Rees RM (2022) Efectos de los f\u00e1rmacos en el ciclo del nitr\u00f3geno en el agua y el suelo: una revisi\u00f3n. Monitoreo y evaluaci\u00f3n ambiental 194(2):105","journal-title":"Monitoreo y evaluaci\u00f3n ambiental"},{"issue":"6","key":"3096_CR29","doi-asserted-by":"publisher","first-page":"588","DOI":"10.5897\/ajar2021.15567","volume":"19","author":"OU Emmanuel","year":"2023","unstructured":"Emmanuel OU, Sheily NE, Nnaemeka ME, Ngozi EA, Godswill CA, Maryrose CN, Nnamdi O, Eugene OO, Goodness O (2023) Mitotic response of Allium cepa L. to toxicity of pharmaceutical effluents. Afr J Agric Res 19(6):588\u2013597. https:\/\/doi.org\/10.5897\/ajar2021.15567","journal-title":"Afr J Agric Res"},{"issue":"4","key":"3096_CR30","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1179\/2047480615Z.000000000329","volume":"24","author":"R Ferrari","year":"2015","unstructured":"Ferrari R (2015) Redacci\u00f3n de revisiones bibliogr\u00e1ficas en estilo narrativo. Med Writ 24(4):230\u2013235. https:\/\/doi.org\/10.1179\/2047480615Z.000000000329","journal-title":"Med Writ"},{"key":"3096_CR31","doi-asserted-by":"publisher","first-page":"126675","DOI":"10.1016\/j.chemosphere.2020.126675","volume":"253","author":"S Garc\u00eda-Medina","year":"2020","unstructured":"Garc\u00eda-Medina S, Galar-Mart\u00ednez M, G\u00f3mez-Oliv\u00e1n LM, Torres-Bezaury DC, Islas-Flores RM, H., Gasca-P\u00e9rez E (2020) The relationship between cyto-genotoxic damage and oxidative stress produced by emerging pollutants on a bioindicator organism (Allium cepa): The carbamazepine case. Chemosphere 253:126675. https:\/\/doi.org\/10.1016\/j.chemosphere.2020.126675","journal-title":"Chemosphere"},{"issue":"3","key":"3096_CR33","doi-asserted-by":"publisher","first-page":"189","DOI":"10.3390\/toxics12030189","volume":"12","author":"B G\u00f6b\u00f6l\u00f6s","year":"2024","unstructured":"G\u00f6b\u00f6l\u00f6s B, Seb\u0151k RE, Szab\u00f3 G, T\u00f3th G, Szoboszlay S, Kriszt B, Kaszab E, H\u00e1hn J (2024) The Cocktail Effects on the Acute Cytotoxicity of Pesticides and Pharmaceuticals Frequently Detected in the Environment. Toxics 12(3):189. https:\/\/doi.org\/10.3390\/toxics12030189","journal-title":"Toxics"},{"key":"3096_CR32","doi-asserted-by":"publisher","unstructured":"Ghadge O, Mahajan S (2024) Evaluation of Synthesised heterocyclic compounds for their Antimitotic activity by Onion Root Tip assay. Asian J Res Pharm Sci 333\u2013338. https:\/\/doi.org\/10.52711\/2231-5659.2024.00053","DOI":"10.52711\/2231-5659.2024.00053"},{"key":"3096_CR34","doi-asserted-by":"publisher","DOI":"10.1016\/j.biortech.2021.126245","author":"R Gondi","year":"2022","unstructured":"Gondi R, Kavitha S, Kannah RY, Dharmapuri BM, Banu R, Tyagi J, V. K., Kumar G (2022) Algal bioremediation of emerging organic pollutants: A review of removals, mechanisms and toxicity levels. Bioresour Technol. https:\/\/doi.org\/10.1016\/j.biortech.2021.126245","journal-title":"Bioresour Technol"},{"issue":"1","key":"3096_CR35","doi-asserted-by":"publisher","first-page":"67","DOI":"10.57188\/manglar.2025.008","volume":"22","author":"LF Gonzales-Llontop","year":"2025","unstructured":"Gonzales-Llontop LF, Roc\u00edo Chot\u00f3n-Calvo D, Chico-Ru\u00edz M, Garc\u00eda-Torres J, M., Mes\u00eda \u00c1C (2025) Efecto toxicol\u00f3gico del fluconazol y del traconazol en una prueba de Allium cepa. Manglar 22(1):67\u201372. https:\/\/doi.org\/10.57188\/manglar.2025.008","journal-title":"Manglar"},{"key":"3096_CR36","unstructured":"Griselda MDJ (2025) Efecto citoprotector de extracto alcoh\u00f3lico de Annona muricata L., frente a la toxicidad inducida con dexametasona en bioensayos con Vicia faba L. https:\/\/hdl.handle.net\/20.500.12918\/10937"},{"key":"3096_CR38","doi-asserted-by":"publisher","first-page":"137318","DOI":"10.1016\/j.chemosphere.2022.137318","volume":"313","author":"M Han","year":"2022","unstructured":"Han M, Zhang Z, Liu S, Sheng Y, Waigi MG, Hu X, Qin C, Ling W (2022) Genotoxicity of organic contaminants in the soil: A review based on bibliometric analysis and methodological progress. Chemosphere 313:137318. https:\/\/doi.org\/10.1016\/j.chemosphere.2022.137318","journal-title":"Chemosphere"},{"key":"3096_CR39","doi-asserted-by":"publisher","first-page":"115892","DOI":"10.1016\/j.envres.2023.115892","volume":"229","author":"S Hern\u00e1ndez","year":"2023","unstructured":"Hern\u00e1ndez S, Melchor E, Gonz\u00e1lez-Gonz\u00e1lez R, Sosa-Hern\u00e1ndez J, Araujo R, Rodr\u00edguez J, Iqbal H (2023) Environmental Concerns and Bioaccumulation of Psychiatric Drugs in Water Bodies Conventional versus Biocatalytic Systems of Mitigation. Environ Res 229:115892","journal-title":"Environ Res"},{"key":"3096_CR37","doi-asserted-by":"publisher","first-page":"892","DOI":"10.1016\/j.chemosphere.2019.02.197","volume":"224","author":"M H\u00e1jkov\u00e1","year":"2019","unstructured":"H\u00e1jkov\u00e1 M, Kummerov\u00e1 M, Zezulka \u0160, Babula P, V\u00e1czi P (2019) Diclofenac as an environmental threat: Impact on the photosynthetic processes of Lemna minor chloroplasts. Chemosphere 224:892\u2013899. https:\/\/doi.org\/10.1016\/j.chemosphere.2019.02.197","journal-title":"Chemosphere"},{"key":"3096_CR40","unstructured":"Iv\u00e1n MG (2023) Actividad genot\u00f3xica y mutag\u00e9nica de vinazas producidas en una planta piloto de producci\u00f3n de bioetanol en Frontino, Antioquia. https:\/\/hdl.handle.net\/10495\/43045"},{"key":"3096_CR41","unstructured":"Janet CA (2024) Efecto de Rhizobium leguminosarum biovar viciae en el rendimiento de variedades y accesiones de arveja (Pisum sativum L.) Pampa del Arco, Ayacucho a 2750 m.s.n.m. https:\/\/repositorio.unsch.edu.pe\/handle\/20.500.14612\/7329"},{"issue":"4","key":"3096_CR42","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.15835\/nbha47411349","volume":"47","author":"A Jit\u0103reanu","year":"2019","unstructured":"Jit\u0103reanu A, Caba I, Trifan A, P\u0103dureanu S, Agoroaei L (2019) Triticum aestivum Assay - A Useful Tool for Environmental Monitoring and Toxicity Assessment. Notulae Botanicae Horti Agrobotanici Cluj-Napoca 47(4):1005\u20131018. https:\/\/doi.org\/10.15835\/nbha47411349","journal-title":"Notulae Botanicae Horti Agrobotanici Cluj-Napoca"},{"key":"3096_CR43","unstructured":"Jonathan ZMJ (2024) Evaluar el efecto de sustratos org\u00e1nicos sobre la producci\u00f3n del haba (Vicia faba). (Tesina). Universidad Laica Eloy Alfaro de Manab\u00ed, Manta, Ecuador. https:\/\/repositorio.uleam.edu.ec\/handle\/123456789\/7230"},{"issue":"9","key":"3096_CR44","doi-asserted-by":"publisher","first-page":"4642","DOI":"10.3390\/ijms22094642","volume":"22","author":"CA Juan","year":"2021","unstructured":"Juan CA, De la Lastra JMP, Plou FJ, P\u00e9rez-Lebe\u00f1a E (2021) The Chemistry of Reactive Oxygen Species (ROS) Revisited: Outlining Their Role in Biological Macromolecules (DNA, Lipids and Proteins) and Induced Pathologies. Int J Mol Sci 22(9):4642. https:\/\/doi.org\/10.3390\/ijms22094642","journal-title":"Int J Mol Sci"},{"issue":"1","key":"3096_CR45","doi-asserted-by":"publisher","first-page":"76","DOI":"10.18006\/2024.12(1).76.92","volume":"12","author":"K Jyoti","year":"2024","unstructured":"Jyoti K, Soni K, Chandra R (2024) Phytotoxicity and genotoxicity assessment of organic and inorganic contaminants detected in pharmaceutical industrial wastewaters using Vigna radiata and Allium cepa. J Experimental Biology Agricultural Sci 12(1):76\u201392. https:\/\/doi.org\/10.18006\/2024.12(1).76.92","journal-title":"J Experimental Biology Agricultural Sci"},{"key":"3096_CR47","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1007\/s13201-019-1064-z","volume":"9","author":"Vy Kumari","year":"2019","unstructured":"Kumari Vy, Tripathi AK (2019) Caracterizaci\u00f3n de efluentes industriales de productos farmac\u00e9uticos mediante an\u00e1lisis de cromatograf\u00eda de gasesespectrometr\u00eda de masas (GCMS) y transducci\u00f3n de im\u00e1genes por infrarrojos (FTIR) y definici\u00f3n de su toxicidad. Appl Water Sci 9:18","journal-title":"Appl Water Sci"},{"issue":"2","key":"3096_CR46","doi-asserted-by":"publisher","first-page":"420","DOI":"10.60151\/envec\/jqai6367","volume":"42","author":"P Kumar","year":"2024","unstructured":"Kumar P, Prasad VM (2024) Cytotoxic and Mitodepressive Effect of Insecticide Profenofos on Root Meristem of Allium cepa L. Environ Ecol 42(2):420\u2013426. https:\/\/doi.org\/10.60151\/envec\/jqai6367","journal-title":"Environ Ecol"},{"key":"3096_CR48","doi-asserted-by":"publisher","unstructured":"Kummerov\u00e1 M, Zezulka \u0160, Babula P (2024) Response of crop seed germination and primary root elongation to a binary mixture of diclofenac and naproxen. https:\/\/doi.org\/10.1007\/s10646-024-02797-1. Ecotoxicology","DOI":"10.1007\/s10646-024-02797-1"},{"key":"3096_CR49","doi-asserted-by":"publisher","unstructured":"Leit\u00e3o I, Leclercq CC, Ribeiro DM, Renaut J, Almeida AM, Martins LL, Mourato MP (2021a) Stress response of lettuce (Lactuca sativa) to environmental contamination with selected pharmaceuticals: A proteomic study. J Proteom 245104291. https:\/\/doi.org\/10.1016\/j.jprot.2021.104291","DOI":"10.1016\/j.jprot.2021.104291"},{"issue":"6","key":"3096_CR50","doi-asserted-by":"publisher","first-page":"1152","DOI":"10.3390\/plants10061152","volume":"10","author":"I Leit\u00e3o","year":"2021","unstructured":"Leit\u00e3o I, Martins LL, Carvalho L, Oliveira MC, Marques MM, Mourato MP (2021b) Acetaminophen Induces an Antioxidative Response in Lettuce Plants. Plants 10(6):1152. https:\/\/doi.org\/10.3390\/plants10061152","journal-title":"Plants"},{"issue":"1","key":"3096_CR51","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1146\/annurev-cellbio-020520-120627","volume":"36","author":"J Maciejowski","year":"2020","unstructured":"Maciejowski J, Hatch EM (2020) Nuclear Membrane Rupture and Its Consequences. Annu Rev Cell Dev Biol 36(1):85\u2013114. https:\/\/doi.org\/10.1146\/annurev-cellbio-020520-120627","journal-title":"Annu Rev Cell Dev Biol"},{"key":"3096_CR52","doi-asserted-by":"publisher","DOI":"10.1016\/s1636-5410(24)49679-7","author":"V Malan","year":"2024","unstructured":"Malan V, Romana S (2024) Anomal\u00edas cromos\u00f3micas y su diagn\u00f3stico en patolog\u00eda constitucional. EMC - Tratado de Med. https:\/\/doi.org\/10.1016\/s1636-5410(24)49679-7","journal-title":"EMC - Tratado de Med"},{"key":"3096_CR53","doi-asserted-by":"publisher","unstructured":"Mendez NJ, Duran MAG, M\u00e9ndez DAJ (2022) Estudio comparativo del \u00edndice mit\u00f3tico en el meristemo de Allium cepa L. BISTUA REVISTA DE LA FACULTAD DE CIENCIAS BASICAS. 20(1):30\u201333. https:\/\/doi.org\/10.24054\/bistua.v20i1.1158","DOI":"10.24054\/bistua.v20i1.1158"},{"key":"3096_CR54","doi-asserted-by":"publisher","first-page":"103972","DOI":"10.1016\/j.etap.2022.103972","volume":"95","author":"NGA Mendoza","year":"2022","unstructured":"Mendoza NGA, Mercado SAS (2022) Cytogenotoxicity of fifth-generation quaternary ammonium using three plant bioindicators. Environ Toxicol Pharmacol 95:103972. https:\/\/doi.org\/10.1016\/j.etap.2022.103972","journal-title":"Environ Toxicol Pharmacol"},{"key":"3096_CR55","doi-asserted-by":"publisher","first-page":"123377","DOI":"10.1016\/j.jhazmat.2020.123377","volume":"401","author":"F Menger","year":"2021","unstructured":"Menger F, Ahrens L, Wiberg K, Gago-Ferrero P (2021) Suspect screening based on market data of polar halogenated micropollutants in river water. J Hazard Mater 401:123377. https:\/\/doi.org\/10.1016\/j.jhazmat.2020.123377","journal-title":"J Hazard Mater"},{"issue":"37","key":"3096_CR56","doi-asserted-by":"publisher","first-page":"51321","DOI":"10.1007\/s11356-021-14352-0","volume":"28","author":"SAS Mercado","year":"2021","unstructured":"Mercado SAS, Cale\u00f1o JDQ (2021) Use of Lens culinaris Med test as environmental bioindicator to identify the cytogenotoxic effect of paraquat pesticide. Environ Sci Pollut Res 28(37):51321\u201351328. https:\/\/doi.org\/10.1007\/s11356-021-14352-0","journal-title":"Environ Sci Pollut Res"},{"key":"3096_CR57","doi-asserted-by":"publisher","DOI":"10.1007\/s11356-025-36066-3","author":"SAS Mercado","year":"2025","unstructured":"Mercado SAS, Garcia PIS (2025) Cytotoxic analysis of the herbicide picloram utilizing Lens culinaris as an environmental biomarker. Environ Sci Pollut Res. https:\/\/doi.org\/10.1007\/s11356-025-36066-3","journal-title":"Environ Sci Pollut Res"},{"key":"3096_CR58","doi-asserted-by":"publisher","DOI":"10.1007\/s11356-024-35793-3","author":"SAS Mercado","year":"2025","unstructured":"Mercado SAS, Parada CZ (2025) Evaluation of morphological and cytotoxic effects of minoxidil on Phaseolus vulgaris L. as a plant model. Environ Sci Pollut Res. https:\/\/doi.org\/10.1007\/s11356-024-35793-3","journal-title":"Environ Sci Pollut Res"},{"issue":"45","key":"3096_CR59","doi-asserted-by":"publisher","first-page":"27","DOI":"10.22490\/24629448.10144","volume":"23","author":"JC Meza","year":"2025","unstructured":"Meza JC, Vega NA, Salazar SA (2025) Determinaci\u00f3n del da\u00f1o gen\u00e9tico inducido por extracto de Azadirachta indica en linfocitos humanos. Revista Nova publicaci\u00f3n cient\u00edfica En Ciencias biom\u00e9dicas 23(45):27\u201339. https:\/\/doi.org\/10.22490\/24629448.10144","journal-title":"Revista Nova publicaci\u00f3n cient\u00edfica En Ciencias biom\u00e9dicas"},{"key":"3096_CR60","unstructured":"Miriam AT (2023) Evaluaci\u00f3n de riesgo ecotoxicol\u00f3gico en una zona agr\u00edcola-industrial de Tlaxcala. http:\/\/dgsa.uaeh.edu.mx:8080\/jspui\/handle\/231104\/2940"},{"key":"3096_CR61","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2023\/5161017","volume":"2023","author":"JS Mohammed","year":"2023","unstructured":"Mohammed JS, Mustapha Y, Him MA, Danladi ZN (2023) Assessment of Cytogenotoxicity of Plastic Industrial Effluent Using Allium cepa Root Tip Cells. Int J Cell Biology 2023:1\u20137. https:\/\/doi.org\/10.1155\/2023\/5161017","journal-title":"Int J Cell Biology"},{"key":"3096_CR62","doi-asserted-by":"publisher","first-page":"103490","DOI":"10.1016\/j.jwpe.2023.103490","volume":"52","author":"AA Moneer","year":"2023","unstructured":"Moneer AA, Hawash HB, Galhoum AA, Elgarahy AM, Mohamed WA, Samy M, El-Seedi HR, Gaballah MS, Mubarak MF, Attia NF (2023) Occurrence and spatial distribution of pharmaceuticals and personal care products (PPCPs) in the aquatic environment, their characteristics, and adopted legislations. J Water Process Eng 52:103490. https:\/\/doi.org\/10.1016\/j.jwpe.2023.103490","journal-title":"J Water Process Eng"},{"key":"3096_CR63","unstructured":"Morales Alvarado LA (2025) Identificaci\u00f3n de malezas fitoextractoras de cadmio y ars\u00e9nico en terrenos agr\u00edcolas con cultivo de frijol chaucha (Phaseolus vulgaris L.) en Hu\u00e1car-Hu\u00e1nuco 2024. UNIVERSIDAD DE HUANUCO https:\/\/repositorio.udh.edu.pe\/20.500.14257\/6081"},{"issue":"1","key":"3096_CR64","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1080\/02772248.2025.2599868","volume":"108","author":"TM Mora-Mu\u00f1oz","year":"2026","unstructured":"Mora-Mu\u00f1oz TM, Santacruz-Salas AP, G\u00f3mez-Herrera S, Ramirez CL, Morales DC, Irazusta SP (2026) Comprehensive review on the ecotoxicological effects of emerging pollutants: focus on pharmaceutical compounds. Toxicol Environ Chem Reviews 108(1):97\u2013124. https:\/\/doi.org\/10.1080\/02772248.2025.2599868","journal-title":"Toxicol Environ Chem Reviews"},{"key":"3096_CR65","doi-asserted-by":"publisher","unstructured":"Moreira RA, Caldas LL, Esp\u00edndola ELG, Novelli A (2023) Environmental Risk Assessment of Drugs in Tropical Freshwaters Using Ceriodaphnia silvestrii as Test Organism. Bull Environ Contam Toxicol 110(6). https:\/\/doi.org\/10.1007\/s00128-023-03739-z","DOI":"10.1007\/s00128-023-03739-z"},{"issue":"4","key":"3096_CR66","doi-asserted-by":"publisher","first-page":"88","DOI":"10.3390\/mps8040088","volume":"8","author":"D Nicu\u021b\u0103","year":"2025","unstructured":"Nicu\u021b\u0103 D, Grosu L, Patriciu O, Voicu R, Alexa I (2025) The Allium cepa Model: A Review of Its Application as a Cytogenetic Tool for Evaluating the Biosafety Potential of Plant Extracts. Methods Protocols 8(4):88. https:\/\/doi.org\/10.3390\/mps8040088","journal-title":"Methods Protocols"},{"key":"3096_CR67","doi-asserted-by":"crossref","unstructured":"Oftana I, Ancheta SG, Lumogdang L (2024) Cytogenotoxicity evaluation of Flucloxacillin using the Allium cepa assay. Available at SSRN 4921268","DOI":"10.2139\/ssrn.4921268"},{"key":"3096_CR68","unstructured":"Omotola EO, Genthe B, Ndlela L, Olatunji S (2023) 1 junio). Phytotoxicity and apoptotic impact assessment of an over-the-counter drug (paracetamol) residue using Allium cepa as a bioindicator. https:\/\/journals.tasued.edu.ng\/index.php\/tjopas\/article\/view\/5"},{"issue":"7","key":"3096_CR69","doi-asserted-by":"publisher","first-page":"4262","DOI":"10.3390\/ijerph19074262","volume":"19","author":"S Pandolfi","year":"2022","unstructured":"Pandolfi S, Valdenassi L, Bj\u00f8rklund G, Chirumbolo S, Lysiuk R, Lenchyk L, Do\u015fa MD, Fazio S (2022) COVID-19 Medical and Pharmacological Management in the European Countries Compared to Italy: An Overview. Int J Environ Res Public Health 19(7):4262. https:\/\/doi.org\/10.3390\/ijerph19074262","journal-title":"Int J Environ Res Public Health"},{"key":"3096_CR70","doi-asserted-by":"publisher","first-page":"103746","DOI":"10.1016\/j.etap.2021.103746","volume":"88","author":"B Paw\u0142owska","year":"2021","unstructured":"Paw\u0142owska B, Telesi\u0144ski A, Biczak R (2021) Effect of diclofenac and naproxen and their mixture on spring barley seedlings and Heterocypris incongruens. Environ Toxicol Pharmacol 88:103746. https:\/\/doi.org\/10.1016\/j.etap.2021.103746","journal-title":"Environ Toxicol Pharmacol"},{"key":"3096_CR71","unstructured":"Pereira PC, [ (2024) 29 noviembre). Efic\u00e1cia de controle, ecotoxicologia para organismos bioindicadores aqu\u00e1ticos e terrestres, potencial de volatilidade aparente e deriva do herbicida dicamba. https:\/\/repositorio.unesp.br\/entities\/publication\/1fc7f733-609b-43a1-9421-9ce5b04f245e"},{"issue":"02","key":"3096_CR72","doi-asserted-by":"publisher","first-page":"38","DOI":"10.52248\/eb.vol2iss02.39","volume":"2","author":"JCB Perez","year":"2022","unstructured":"Perez JCB, Valverde IRT, Castro JaV (2022) Bioensayos de toxicidad aguda de extractos vegetales con Daphnia magna: un camino eficaz hacia el desarrollo sostenible. Revista Cient\u00edfica BIOTECH Eng 2(02):38\u201349. https:\/\/doi.org\/10.52248\/eb.vol2iss02.39","journal-title":"Revista Cient\u00edfica BIOTECH Eng"},{"issue":"2","key":"3096_CR73","first-page":"8","volume":"3","author":"C Quintana","year":"2024","unstructured":"Quintana C, Nu\u00f1ez AC, Vazquez JSL, Moreno-V\u00e1zquez O, Cabrera-Hern\u00e1ndez A (2024) Efectos combinados de bismuto y detergente en la germinaci\u00f3n y crecimiento inicial de lenteja (Lens culinaris). Revista Multidisciplinaria de Ciencia Innovaci\u00f3n y Desarrollo 3(2):8\u201349","journal-title":"Revista Multidisciplinaria de Ciencia Innovaci\u00f3n y Desarrollo"},{"key":"3096_CR74","doi-asserted-by":"publisher","first-page":"e68303","DOI":"10.4025\/actascibiolsci.v46i1.68303","volume":"46","author":"JC Rampanelli","year":"2024","unstructured":"Rampanelli JC, Zuchello F, Mores R (2024) Analysis of cytotoxicity and genotoxicity of sweeteners using Allium cepa bioassays. Acta Scientiarum Biol Sci 46:e68303. https:\/\/doi.org\/10.4025\/actascibiolsci.v46i1.68303","journal-title":"Acta Scientiarum Biol Sci"},{"key":"3096_CR75","doi-asserted-by":"publisher","first-page":"102616","DOI":"10.1016\/j.jwpe.2022.102616","volume":"46","author":"A Rempel","year":"2022","unstructured":"Rempel A, Gutkoski J, Torres Nazari M, Nadal Biolchi G, Biduski B, Treichel H, Colla L (2022) Microalgae Growth with a High Concentration of Emerging Pollutants and Phytotoxicity Evaluation of Cultivation Wastewater. J Water Process Eng 46:102616. https:\/\/doi.org\/10.1016\/j.jwpe.2022.102616","journal-title":"J Water Process Eng"},{"key":"3096_CR76","doi-asserted-by":"publisher","first-page":"155105","DOI":"10.1016\/j.scitotenv.2022.155105","volume":"833","author":"MT Rose","year":"2022","unstructured":"Rose MT, Zhang P, Rose TJ, Scanlan CA, McGrath G, Van Zwieten L (2022) Herbicide residues in Australian grain cropping soils at sowing and their relevance to crop growth. Sci Total Environ 833:155105. https:\/\/doi.org\/10.1016\/j.scitotenv.2022.155105","journal-title":"Sci Total Environ"},{"issue":"39","key":"3096_CR77","doi-asserted-by":"publisher","first-page":"51114","DOI":"10.1007\/s11356-024-34521-1","volume":"31","author":"S Salazar","year":"2024","unstructured":"Salazar S, Carre\u00f1o RDC (2024) Examining the interaction between pesticides and bioindicator plants: an in-depth analysis of their cytotoxicity. Environ Sci Pollut Res 31(39):51114\u201351125. https:\/\/doi.org\/10.1007\/s11356-024-34521-1","journal-title":"Environ Sci Pollut Res"},{"key":"3096_CR78","doi-asserted-by":"publisher","unstructured":"Salazar S, Galvis DGV (2023) Paracetamol ecotoxicological bioassay using the bioindicators Lens culinaris Med. and Pisum sativum L. c And Pollution Research, 30(22), 61965\u201361976. https:\/\/doi.org\/10.1007\/s11356-023-26475-7","DOI":"10.1007\/s11356-023-26475-7"},{"key":"3096_CR79","doi-asserted-by":"publisher","DOI":"10.1007\/s11356-025-36247-0","author":"S Salazar","year":"2025","unstructured":"Salazar S, Zambrano C (2025) Bioassay of toxicity of acid mine drainage treated and untreated with lime ash using the bioindicator Pisum sativum L. Environ Sci Pollut Res. https:\/\/doi.org\/10.1007\/s11356-025-36247-0","journal-title":"Environ Sci Pollut Res"},{"issue":"7","key":"3096_CR80","doi-asserted-by":"publisher","first-page":"3279","DOI":"10.3390\/ijms26073279","volume":"26","author":"Y Salinas","year":"2025","unstructured":"Salinas Y, Chauhan SC, Bandyopadhyay D (2025) Small-Molecule Mitotic Inhibitors as Anticancer Agents: Discovery, Classification, Mechanisms of Action, and Clinical Trials. Int J Mol Sci 26(7):3279. https:\/\/doi.org\/10.3390\/ijms26073279","journal-title":"Int J Mol Sci"},{"key":"3096_CR81","doi-asserted-by":"publisher","first-page":"100076","DOI":"10.1016\/j.nexus.2022.100076","volume":"6","author":"K Samal","year":"2022","unstructured":"Samal K, Mahapatra Sy, Ali MH (2022) Aguas residuales farmac\u00e9uticas como contaminantes emergentes (CE): Tecnolog\u00edas de tratamiento, impacto en el medio ambiente y la salud humana. Energy Nexus 6:100076","journal-title":"Energy Nexus"},{"issue":"2","key":"3096_CR82","doi-asserted-by":"publisher","first-page":"327","DOI":"10.51470\/plantarchives.2022.v22.no2.056","volume":"22","author":"S Saxena","year":"2022","unstructured":"Saxena S (2022) CHROMOSOMAL ABERRATIONS IN PLANT BIOASSAYS: a REVIEW. PLANT ARCHIVES 22(2):327\u2013330. https:\/\/doi.org\/10.51470\/plantarchives.2022.v22.no2.056","journal-title":"PLANT ARCHIVES"},{"key":"3096_CR83","doi-asserted-by":"publisher","unstructured":"Shaalan WM, Sayed AEH (2025) Toxicity of pharmaceutical micropollutants on common carp (Cyprinus carpio) using blood biomarkers. Sci Rep 15(1). https:\/\/doi.org\/10.1038\/s41598-025-01434-z","DOI":"10.1038\/s41598-025-01434-z"},{"issue":"3","key":"3096_CR84","doi-asserted-by":"publisher","first-page":"71","DOI":"10.9734\/ajob\/2025\/v21i3492","volume":"21","author":"S Shandilya","year":"2025","unstructured":"Shandilya S, Anuraj N, Kumar A, Kumari D (2025) Toxicological Bioassay of Paracetamol Using Allium cepa as a Bioindicator. Asian J Biology 21(3):71\u201380. https:\/\/doi.org\/10.9734\/ajob\/2025\/v21i3492","journal-title":"Asian J Biology"},{"key":"3096_CR85","doi-asserted-by":"publisher","unstructured":"Shokoohi R, Ghiasvand MA, Jafari AJ (2020). Antibiotic Detection in a Hospital Wastewater and Comparison of Their Removal Rate Bay Activated Sludge and Earthworm-Based Vermifilteration: Environmental Risk Assessment. Process Saf Environ Prot 134:169\u2013177. https:\/\/doi.org\/10.1016\/j.psep.2019.10.020","DOI":"10.1016\/j.psep.2019.10.020"},{"issue":"24","key":"3096_CR86","doi-asserted-by":"publisher","first-page":"3815","DOI":"10.3390\/plants14243815","volume":"14","author":"A Siemieniuk","year":"2025","unstructured":"Siemieniuk A, Rudnicka M, Jemio\u0142a G, Ma\u0142kowski E (2025) Hormesis as a Particular Type of Plant Stress Response. Plants 14(24):3815. https:\/\/doi.org\/10.3390\/plants14243815","journal-title":"Plants"},{"key":"3096_CR87","doi-asserted-by":"publisher","unstructured":"Singh CK, Sodhi KK, Rajagopalan VN, Sharma V, Kaur S, J., Kumar Y (2025) Managing the complexity of emerging contaminants in aquatic environments: exploring their ecotoxicological impacts, detection techniques, and the use of innovative technologies for their remediation. Discover Catal 2(1). https:\/\/doi.org\/10.1007\/s44344-025-00013-8","DOI":"10.1007\/s44344-025-00013-8"},{"key":"3096_CR88","doi-asserted-by":"publisher","DOI":"10.1093\/inteam\/vjaf082","author":"DS Singh","year":"2025","unstructured":"Singh DS, Pflugmacher S (2025) Ecotoxicological assessments of over-the-counter NSAID (diclofenac, ibuprofen, aspirin) and antipyretic (acetaminophen) pharmaceuticals: A review of their toxicity effects on aquatic crustaceans. Integr Environ Assess Manag. https:\/\/doi.org\/10.1093\/inteam\/vjaf082","journal-title":"Integr Environ Assess Manag"},{"key":"3096_CR89","doi-asserted-by":"publisher","unstructured":"Singh M, Chadha P (2024) Assessment of synthetic food dye erythrosine induced cytotoxicity, genotoxicity, biochemical and molecular alterations in Allium cepa root meristematic cells: insights from in silico study. Toxicol Res 13(4). https:\/\/doi.org\/10.1093\/toxres\/tfae126","DOI":"10.1093\/toxres\/tfae126"},{"issue":"1","key":"3096_CR90","doi-asserted-by":"publisher","first-page":"025","DOI":"10.17352\/aest.000067","volume":"7","author":"DJ Souki","year":"2023","unstructured":"Souki DJ, Gabriel DS, Ribeiro DSC, Alvarenga DPFL, Souki PAL, Rocha PB, Paulo GMM, Rosa SM (2023) Cytotoxicity, genotoxicity, and mutagenicity of the active pharmaceutical ingredient nevirapine and a nevirapine-based drug on the plant species Allium cepa. Annals Environ Sci Toxicol 7(1):025\u2013033. https:\/\/doi.org\/10.17352\/aest.000067","journal-title":"Annals Environ Sci Toxicol"},{"key":"3096_CR91","doi-asserted-by":"publisher","unstructured":"Sultan MB, Anik AHy, Rahman MM (2024) Contaminantes emergentes y sus posibles impactos en los ecosistemas estuarinos: \u00bfEstamos al tanto? Bolet\u00edn de Contaminaci\u00f3n Marina. 199:115982. https:\/\/doi.org\/10.1016\/j.marpolbul.2023.115982","DOI":"10.1016\/j.marpolbul.2023.115982"},{"key":"3096_CR92","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1016\/j.toxrep.2022.03.035","volume":"9","author":"AM Tawfik","year":"2022","unstructured":"Tawfik AM, Mostafa EM, Abd-Elrahman KM (2022) Egyptian perspectives on potential risk of paracetamol\/acetaminophen-induced toxicities: Lessons learnt during COVID-19 pandemic. Toxicol Rep 9:541\u2013548. https:\/\/doi.org\/10.1016\/j.toxrep.2022.03.035","journal-title":"Toxicol Rep"},{"key":"3096_CR93","doi-asserted-by":"publisher","DOI":"10.15741\/revbio.11.e1650","author":"DO Torres-Bugar\u00edn","year":"2024","unstructured":"Torres-Bugar\u00edn DO, Mart\u00ednez RS, Barajas AJG, R\u00edos-Esquivel PE, Ibarra MLR, Garcia EA (2024) Micron\u00facleos y anormalidades nucleares en c\u00e9lulas epiteliales orales: Herramienta eficaz y sencilla en la detecci\u00f3n temprana de individuos altamente susceptibles a la inestabilidad gen\u00f3mica. Revista Bio Ciencias. https:\/\/doi.org\/10.15741\/revbio.11.e1650","journal-title":"Revista Bio Ciencias"},{"key":"3096_CR94","doi-asserted-by":"publisher","first-page":"111396","DOI":"10.1016\/j.envres.2021.111396","volume":"200","author":"C Trombini","year":"2021","unstructured":"Trombini C, Kazakova J, Montilla-L\u00f3pez A, Fern\u00e1ndez-Cisnal R, Hampel M, Fern\u00e1ndez-Torres R, Bello-L\u00f3pez M\u00c1, Abril N, Blasco J (2021) Assessment of pharmaceutical mixture (ibuprofen, ciprofloxacin and flumequine) effects to the crayfish Procambarus clarkii: A multilevel analysis (biochemical, transcriptional and proteomic approaches). Environ Res 200:111396. https:\/\/doi.org\/10.1016\/j.envres.2021.111396","journal-title":"Environ Res"},{"issue":"6","key":"3096_CR95","doi-asserted-by":"publisher","first-page":"170","DOI":"10.12911\/22998993\/202348","volume":"26","author":"K Tsytlishvili","year":"2025","unstructured":"Tsytlishvili K (2025) Performing acute phytotoxicity of widely used drugs on germination and root elongation of <\u2009i>Lactuca sativa\u2009L. J Ecol Eng 26(6):170\u2013178. https:\/\/doi.org\/10.12911\/22998993\/202348","journal-title":"J Ecol Eng"},{"key":"3096_CR96","doi-asserted-by":"publisher","unstructured":"Vega-Contreras NA, Hurtado MCA, M\u00e1rquez CyS (2024) Efectos de dos herbicidas org\u00e1nicos sobre la fisiolog\u00eda de la germinaci\u00f3n en Coffea arabica. Ciencia y Tecnolog\u00eda Agropecuaria 25(2). https:\/\/doi.org\/10.21930\/rcta.vol25_num2_art:3305","DOI":"10.21930\/rcta.vol25_num2_art:3305"},{"key":"3096_CR97","doi-asserted-by":"publisher","first-page":"119310","DOI":"10.1016\/j.envpol.2022.119310","volume":"305","author":"P Wang","year":"2022","unstructured":"Wang P, Yuan Q, Wang X, Hu B, Liu S, Ma J (2022) Abundant microbial communities act as more sensitive bio-indicators for ecological evaluation of copper mine contamination than rare taxa in river sediments. Environ Pollut 305:119310. https:\/\/doi.org\/10.1016\/j.envpol.2022.119310","journal-title":"Environ Pollut"},{"key":"3096_CR98","doi-asserted-by":"publisher","first-page":"145779","DOI":"10.1016\/j.scitotenv.2021.145779","volume":"774","author":"L Wiest","year":"2021","unstructured":"Wiest L, Gosset A, Fildier A, Libert C, Herv\u00e9 M, Sibeud E, Vulliet E (2021) Occurrence and removal of emerging pollutants in urban sewage treatment plants using LC-QToF MS suspect screening and quantification. Sci Total Environ 774:145779. https:\/\/doi.org\/10.1016\/j.scitotenv.2021.145779","journal-title":"Sci Total Environ"},{"issue":"5","key":"3096_CR99","doi-asserted-by":"publisher","first-page":"967","DOI":"10.1002\/etc.4687","volume":"39","author":"AM Wormington","year":"2020","unstructured":"Wormington AM, De Mar\u00eda M, Kurita H, Bisesi Jr JH, Denslow ND, Martyniuk CJ (2020) Antineoplastic agents: Environmental prevalence and adverse outcomes in aquatic organisms. Environ Toxicol Chem 39(5):967\u2013985. https:\/\/doi.org\/10.1002\/etc.4687","journal-title":"Environ Toxicol Chem"},{"issue":"6","key":"3096_CR100","doi-asserted-by":"publisher","first-page":"1260","DOI":"10.3390\/agronomy14061260","volume":"14","author":"B Zhang","year":"2024","unstructured":"Zhang B, Lv F, Yang J (2024) Pesticides Toxicity, Removal and Detoxification in Plants: A Review. Agronomy 14(6):1260. https:\/\/doi.org\/10.3390\/agronomy14061260","journal-title":"Agronomy"},{"key":"3096_CR101","doi-asserted-by":"publisher","first-page":"128456","DOI":"10.1016\/j.jhazmat.2022.128456","volume":"431","author":"M Zhang","year":"2022","unstructured":"Zhang M, Sun Q, Chen P, Wei X, Wang B (2022) How microorganisms tell the truth of potentially toxic elements pollution in environment. J Hazard Mater 431:128456. https:\/\/doi.org\/10.1016\/j.jhazmat.2022.128456","journal-title":"J Hazard Mater"}],"container-title":["Ecotoxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10646-026-03096-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10646-026-03096-7","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10646-026-03096-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T11:02:48Z","timestamp":1785841368000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10646-026-03096-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,28]]},"references-count":101,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["3096"],"URL":"https:\/\/doi.org\/10.1007\/s10646-026-03096-7","relation":{},"ISSN":["0963-9292","1573-3017"],"issn-type":[{"value":"0963-9292","type":"print"},{"value":"1573-3017","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,28]]},"assertion":[{"value":"23 October 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 April 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 April 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Written informed consent was obtained from individual or guardian participants.","order":1,"name":"Ethics","label":"Consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","label":"Conflict of interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"108"}}