{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T14:02:16Z","timestamp":1788184936582,"version":"build-2803163510"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2010,6,24]],"date-time":"2010-06-24T00:00:00Z","timestamp":1277337600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Environ Geochem Health"],"published-print":{"date-parts":[[2011,4]]},"DOI":"10.1007\/s10653-010-9331-9","type":"journal-article","created":{"date-parts":[[2010,6,23]],"date-time":"2010-06-23T06:01:39Z","timestamp":1277272899000},"page":"183-188","source":"Crossref","is-referenced-by-count":50,"title":["Is selenium deficiency really the cause of Keshan disease?"],"prefix":"10.1007","volume":"33","author":[{"given":"Cong","family":"Lei","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaolin","family":"Niu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangke","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2010,6,24]]},"reference":[{"key":"9331_CR1","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1056\/NEJMoa030535","volume":"349","author":"S Blankenberg","year":"2003","unstructured":"Blankenberg, S., Rupprecht, H. J., Bickel, C., Torzewski, M., Hafner, G., Tiret, L., et al. (2003). Glutathione peroxidase 1 activity and cardiovascular events in patients with coronary artery disease. New England Journal of Medicine, 349, 1605\u20131613.","journal-title":"New England Journal of Medicine"},{"key":"9331_CR2","doi-asserted-by":"crossref","first-page":"1888","DOI":"10.1053\/euhj.2000.2246","volume":"21","author":"C Bruch","year":"2000","unstructured":"Bruch, C., Schmermund, A., Marin, D., Katz, M., Bartel, T., Schaar, J., et al. (2000). Tei-index in patients with mild-to-moderate congestive heart failure. European Heart Journal, 21, 1888\u20131895.","journal-title":"European Heart Journal"},{"key":"9331_CR3","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1258\/jrsm.95.4.219-a","volume":"95","author":"TO Cheng","year":"2002","unstructured":"Cheng, T. O. (2002). Selenium deficiency and cardiomyopathy. Journal of the Royal Society of Medicine, 95, 219\u2013220.","journal-title":"Journal of the Royal Society of Medicine"},{"key":"9331_CR4","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1054\/jcaf.2001.23244","volume":"7","author":"ER Ernst","year":"2001","unstructured":"Ernst, E. R., Shub, C., Bailey, K. R., Brown, L. R., & Redfield, M. M. (2001). Radiographic measurements of cardiac size as predictors of outcome in patients with dilated cardiomyopathy. Journal of Cardiac Failure, 7, 13\u201320.","journal-title":"Journal of Cardiac Failure"},{"key":"9331_CR5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF00644785","volume":"401","author":"K Ge","year":"1983","unstructured":"Ge, K., Xue, A., Bai, J., & Wang, S. (1983). Keshan disease-an endemic cardiomyopathy in China. Virchows Archiv. A, Pathological anatomy and histopathology, 401, 1\u201315.","journal-title":"Virchows Archiv. A, Pathological anatomy and histopathology"},{"key":"9331_CR6","first-page":"251","volume":"96","author":"BQ Gu","year":"1983","unstructured":"Gu, B. Q. (1983). Pathology of Keshan disease. A comprehensive review. Chinese Medical Journal (Engl), 96, 251\u2013261.","journal-title":"Chinese Medical Journal (Engl)"},{"key":"9331_CR7","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.cca.2008.09.025","volume":"399","author":"C Lei","year":"2009","unstructured":"Lei, C., Niu, X., Wei, J., Zhu, J., & Zhu, Y. (2009). Interaction of glutathione peroxidase-1 and selenium in endemic dilated cardiomyopathy. Clinica Chimica Acta, 399, 102\u2013108.","journal-title":"Clinica Chimica Acta"},{"key":"9331_CR8","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1056\/NEJM199810153391604","volume":"339","author":"R Moreno-Reyes","year":"1998","unstructured":"Moreno-Reyes, R., Suetens, C., Mathieu, F., Begaux, F., Zhu, D., Rivera, M. T., et al. (1998). Kashin-Beck osteoarthropathy in rural Tibet in relation to selenium and iodine status. New England Journal of Medicine, 339, 1112\u20131120.","journal-title":"New England Journal of Medicine"},{"key":"9331_CR9","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/0009-8981(83)90062-1","volume":"128","author":"O Oster","year":"1983","unstructured":"Oster, O., Prellwitz, W., Kasper, W., & Meinertz, T. (1983). Congestive cardiomyopathy and the selenium content of serum. Clinica Chimica Acta, 128, 125\u2013132.","journal-title":"Clinica Chimica Acta"},{"key":"9331_CR10","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/S0894-7317(89)80013-6","volume":"2","author":"NB Schiller","year":"1989","unstructured":"Schiller, N. B., Shah, P. M., Crawford, M., DeMaria, A., Devereux, R., Feigenbaum, H., et al. (1989). Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. American Society of Echocardiography committee on standards, subcommittee on quantitation of two-dimensional echocardiograms. Journal of the American Society of Echocardiography, 2, 358\u2013367.","journal-title":"Journal of the American Society of Echocardiography"},{"key":"9331_CR11","first-page":"135","volume":"26","author":"C Tei","year":"1995","unstructured":"Tei, C. (1995). New non-invasive index for combined systolic and diastolic ventricular function. Journal of Cardiology, 26, 135\u2013136.","journal-title":"Journal of Cardiology"},{"key":"9331_CR12","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/0735-1097(96)00202-1","volume":"28","author":"C Tei","year":"1996","unstructured":"Tei, C., Dujardin, K. S., Hodge, D. O., Kyle, R. A., Tajik, A. J., & Seward, J. B. (1996). Doppler index combining systolic and diastolic myocardial performance: clinical value in cardiac amyloidosis. Journal of the American College of Cardiology, 28, 658\u2013664.","journal-title":"Journal of the American College of Cardiology"},{"key":"9331_CR13","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1093\/ajcn\/48.2.316","volume":"48","author":"CD Thomson","year":"1988","unstructured":"Thomson, C. D., Steven, S. M., van Rij, A. M., Wade, C. R., & Robinson, M. F. (1988). Selenium and vitamin E supplementation: activities of glutathione peroxidase in human tissues. American Journal of Clinical Nutrition, 48, 316\u2013323.","journal-title":"American Journal of Clinical Nutrition"},{"key":"9331_CR14","first-page":"313","volume":"14","author":"GQ Yang","year":"1983","unstructured":"Yang, G. Q. (1983). The relationship between selenium and etiology of Keshan disease. Sheng Li Ke Xue Jin Zhan, 14, 313\u2013317.","journal-title":"Sheng Li Ke Xue Jin Zhan"},{"key":"9331_CR15","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.tox.2006.06.008","volume":"226","author":"MS Yang","year":"2006","unstructured":"Yang, M. S., Chan, H. W., & Yu, L. C. (2006). Glutathione peroxidase and glutathione reductase activities are partially responsible for determining the susceptibility of cells to oxidative stress. Toxicology, 226, 126\u2013130.","journal-title":"Toxicology"},{"key":"9331_CR16","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1007\/978-1-4613-2801-8_8","volume":"6","author":"GQ Yang","year":"1984","unstructured":"Yang, G. Q., Chen, J. S., Wen, Z. M., Ge, K. Y., Zhu, L. Z., Chen, X. C., et al. (1984). The role of selenium in Keshan disease. Advances in Nutritional Research, 6, 203\u2013231.","journal-title":"Advances in Nutritional Research"},{"key":"9331_CR17","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1253\/jcj.46.1201","volume":"46","author":"WH Yu","year":"1982","unstructured":"Yu, W. H. (1982). A study of nutritional and bio-geochemical factors in the occurrence and development of Keshan disease. Japanese Circulation Journal, 46, 1201\u20131207.","journal-title":"Japanese Circulation Journal"},{"key":"9331_CR18","first-page":"874","volume":"19","author":"PL Yu","year":"1988","unstructured":"Yu, P. L. (1988). Keshan disease: an entity or not. Human Pathology, 19, 874.","journal-title":"Human Pathology"}],"container-title":["Environmental Geochemistry and Health"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10653-010-9331-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10653-010-9331-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10653-010-9331-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,30]],"date-time":"2019-05-30T20:33:10Z","timestamp":1559248390000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10653-010-9331-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,6,24]]},"references-count":18,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2011,4]]}},"alternative-id":["9331"],"URL":"https:\/\/doi.org\/10.1007\/s10653-010-9331-9","relation":{},"ISSN":["0269-4042","1573-2983"],"issn-type":[{"value":"0269-4042","type":"print"},{"value":"1573-2983","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,6,24]]}}}