{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T21:57:44Z","timestamp":1793743064183,"version":"4.6.1"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2014,5,1]],"date-time":"2014-05-01T00:00:00Z","timestamp":1398902400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Epidemiol"],"published-print":{"date-parts":[[2014,5]]},"DOI":"10.1007\/s10654-014-9890-7","type":"journal-article","created":{"date-parts":[[2014,5,19]],"date-time":"2014-05-19T04:23:57Z","timestamp":1400473437000},"page":"371-382","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":335,"title":["The German National Cohort: aims, study design and organization"],"prefix":"10.1007","volume":"29","author":[{"name":"German National Cohort (GNC) Consortium","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2014,5,20]]},"reference":[{"key":"9890_CR1","unstructured":"RKI. Gesundheit in Deutschland. Berlin: Robert Koch Institut; 2007. ISBN 3-89606-173-9."},{"issue":"3","key":"9890_CR2","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1093\/pubmed\/fdp079","volume":"32","author":"DR Rappange","year":"2010","unstructured":"Rappange DR, Brouwer WB, Rutten FF, van Baal PH. Lifestyle intervention: from cost savings to value for money. J Public Health. 2010;32(3):440\u20137.","journal-title":"J Public Health"},{"issue":"2","key":"9890_CR3","doi-asserted-by":"crossref","first-page":"e29","DOI":"10.1371\/journal.pmed.0050029","volume":"5","author":"PH Baal Van","year":"2008","unstructured":"Van Baal PH, Polder JJ, de Wit GA, Hoogenveen RT, Feenstra TL, Boshuizen HC, et al. Lifetime medical costs of obesity: prevention no cure for increasing health expenditure. PLoS Med. 2008;5(2):e29.","journal-title":"PLoS Med"},{"issue":"3","key":"9890_CR4","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1007\/s10654-009-9317-z","volume":"24","author":"KH Greiser","year":"2009","unstructured":"Greiser KH, Kluttig A, Schumann B, Swenne CA, Kors JA, Kuss O, et al. Cardiovascular diseases, risk factors and short-term heart rate variability in an elderly general population: the CARLA study 2002\u20132006. Eur J Epidemiol. 2009;24(3):123\u201342.","journal-title":"Eur J Epidemiol"},{"issue":"4","key":"9890_CR5","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1159\/000012789","volume":"43","author":"M Bergmann","year":"1999","unstructured":"Bergmann M, Bussas U, Boeing H. Follow-up procedures in EPIC-Germany\u2014data quality aspects. Ann Nutr Metab. 1999;43(4):225\u201334.","journal-title":"Ann Nutr Metab"},{"issue":"S 01","key":"9890_CR6","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1055\/s-2005-858235","volume":"67","author":"R Holle","year":"2005","unstructured":"Holle R, Happich M, L\u00f6wel H, Wichmann H. KORA\u2014a research platform for population based health research. Das Gesundheitswesen. 2005;67(S 01):19\u201325.","journal-title":"Das Gesundheitswesen"},{"issue":"3","key":"9890_CR7","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1007\/BF01324255","volume":"46","author":"U John","year":"2001","unstructured":"John U, Hensel E, L\u00fcdemann J, Piek M, Sauer S, Adam C, et al. Study of Health In Pomerania (SHIP): a health examination survey in an east German region: objectives and design. Sozial-und Pr\u00e4ventivmedizin. 2001;46(3):186\u201394.","journal-title":"Sozial-und Pr\u00e4ventivmedizin"},{"issue":"2","key":"9890_CR8","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1067\/mhj.2002.123579","volume":"144","author":"A Schmermund","year":"2002","unstructured":"Schmermund A, Mohlenkamp S, Stang A, Gronemeyer D, Seibel R, Hirche H, et al. Assessment of clinically silent atherosclerotic disease and established and novel risk factors for predicting myocardial infarction and cardiac death in healthy middle-aged subjects: rationale and design of the Heinz Nixdorf Recall Study. Risk factors, evaluation of coronary calcium and lifestyle. Am Heart J. 2002;144(2):212\u20138.","journal-title":"Am Heart J"},{"key":"9890_CR9","unstructured":"Bellach B-M, Knopf H, Thefeld W. The German Health Survey. 1997\/98. Gesundheitswesen [Bundesverband der \u00c4rzte des \u00d6ffentlichen Gesundheitsdienstes (Germany)]. 1998;60:S59."},{"issue":"1","key":"9890_CR10","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1186\/1471-2458-10-479","volume":"10","author":"M Zins","year":"2010","unstructured":"Zins M, Bonenfant S, Carton M, Coeuret-Pellicer M, Gu\u00e9guen A, Gourmelen J, et al. The CONSTANCES cohort: an open epidemiological laboratory. BMC Public Health. 2010;10(1):479.","journal-title":"BMC Public Health"},{"key":"9890_CR11","unstructured":"LifeGene. 2013. https:\/\/www.lifegene.se\/For-scientists\/Questionnaire-Overview-\/ . Accessed 29 Apr 2013."},{"key":"9890_CR12","unstructured":"Biobank U. 2013. http:\/\/www.ukbiobank.ac.uk\/wp-content\/uploads\/2011\/11\/UK-Biobank-Protocol.pdf?phpMyAdmin=trmKQlYdjjnQIgJ%2CfAzikMhEnx6 . Accessed 20 Aug 2013."},{"key":"9890_CR13","doi-asserted-by":"crossref","unstructured":"Dent THS. Predicting the risk of coronary heart disease II: the role of novel molecular biomarkers and genetics in estimating risk, and the future of risk prediction. Atherosclerosis. 2010;213(2):352\u201362.","DOI":"10.1016\/j.atherosclerosis.2010.06.021"},{"issue":"26","key":"9890_CR14","doi-asserted-by":"crossref","first-page":"2796","DOI":"10.1056\/NEJMsa0708739","volume":"358","author":"PD Pharoah","year":"2008","unstructured":"Pharoah PD, Antoniou AC, Easton DF, Ponder BA. Polygenes, risk prediction, and targeted prevention of breast cancer. N Engl J Med. 2008;358(26):2796\u2013803.","journal-title":"N Engl J Med"},{"issue":"4","key":"9890_CR15","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1080\/03630242.2012.678476","volume":"52","author":"T Seyednoori","year":"2012","unstructured":"Seyednoori T, Pakseresht S, Roushan Z. Risk of developing breast cancer by utilizing Gail model. Women Health. 2012;52(4):391\u2013402.","journal-title":"Women Health"},{"issue":"1","key":"9890_CR16","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1093\/jnci\/djp438","volume":"102","author":"GL Anderson","year":"2010","unstructured":"Anderson GL, McIntosh M, Wu L, Barnett M, Goodman G, Thorpe JD, et al. Assessing lead time of selected ovarian cancer biomarkers: a nested case-control study. J Natl Cancer Inst. 2010;102(1):26\u201338. doi: 10.1093\/jnci\/djp438 .","journal-title":"J Natl Cancer Inst"},{"issue":"2","key":"9890_CR17","doi-asserted-by":"crossref","first-page":"249","DOI":"10.2174\/156652410790963277","volume":"10","author":"M Sikaroodi","year":"2010","unstructured":"Sikaroodi M, Galachiantz Y, Baranova A. Tumor markers: the potential of omics approach. Curr Mol Med. 2010;10(2):249\u201357.","journal-title":"Curr Mol Med"},{"issue":"11","key":"9890_CR18","doi-asserted-by":"crossref","first-page":"800","DOI":"10.2459\/JCM.0b013e32834a658f","volume":"12","author":"G Mercuro","year":"2011","unstructured":"Mercuro G, Bassareo PP, Deidda M, Cadeddu C, Barberini L, Atzori L. Metabolomics: a new era in cardiology? J Cardiovasc Med. 2011;12(11):800\u20135.","journal-title":"J Cardiovasc Med"},{"issue":"1","key":"9890_CR19","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.pcad.2012.06.004","volume":"55","author":"T Senn","year":"2012","unstructured":"Senn T, Hazen SL, Tang W. Translating metabolomics to cardiovascular biomarkers. Prog Cardiovasc Dis. 2012;55(1):70\u20136.","journal-title":"Prog Cardiovasc Dis"},{"key":"9890_CR20","doi-asserted-by":"crossref","unstructured":"Tiller D, Kluttig A, Schumann B, Werdan K, Haerting J, Greiser K. Response der CARLA-follow-up Untersuchung (2007\u20132010). Gesundheitswesen. 2010;72:V184.","DOI":"10.1055\/s-0030-1266365"},{"key":"9890_CR21","doi-asserted-by":"crossref","unstructured":"Erbel R, Mohlenkamp S, Moebus S, Schmermund A, Lehmann N, Stang A et al. Coronary risk stratification, discrimination, and reclassification improvement based on quantification of subclinical coronary atherosclerosis: the Heinz Nixdorf Recall Study. J Am Coll Cardiol. 2010;56:1397\u2013406.","DOI":"10.1016\/j.jacc.2010.06.030"},{"key":"9890_CR22","unstructured":"WHO. ICD-10 classifications of mental and behavioural disorder: clinical descriptions and diagnostic guidelines. Geneva: World Health Organisation; 1992."},{"key":"9890_CR23","volume-title":"Krebs in Deutschland 2005\/2006: H\u00e4ufigkeiten und Trends","author":"G Husmann","year":"2010","unstructured":"Husmann G, Kaatsch P, Katalinic A, Bertz J, Haberland J, Kraywinkel K, et al. Krebs in Deutschland 2005\/2006: H\u00e4ufigkeiten und Trends. Berlin: Robert Koch-Institut; 2010."},{"key":"9890_CR24","unstructured":"Bundesdatenschutzgesetz in der Fassung der Bekanntmachung vom 14. January 2003 (BGBl. I S. 66), das zuletzt durch Artikel 1 des Gesetzes vom 14. August 2009 (BGBl. I S. 2814) ge\u00e4ndert worden ist. 2010. http:\/\/www.gesetze-im-internet.de\/bundesrecht\/bdsg_1990\/gesamt.pdf . Last access 10.2010."},{"key":"9890_CR25","volume-title":"Human biobanks for research\u2014opinion","author":"German Ethics Council","year":"2010","unstructured":"German Ethics Council. Human biobanks for research\u2014opinion. Berlin: German Ethics Council; 2010."}],"container-title":["European Journal of Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10654-014-9890-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10654-014-9890-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10654-014-9890-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,3,26]],"date-time":"2019-03-26T18:53:14Z","timestamp":1553626394000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10654-014-9890-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,5]]},"references-count":25,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2014,5]]}},"alternative-id":["9890"],"URL":"https:\/\/doi.org\/10.1007\/s10654-014-9890-7","relation":{},"ISSN":["0393-2990","1573-7284"],"issn-type":[{"value":"0393-2990","type":"print"},{"value":"1573-7284","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,5]]}}}