{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:17:01Z","timestamp":1792783021923,"version":"4.5.0"},"reference-count":93,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T00:00:00Z","timestamp":1791763200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T00:00:00Z","timestamp":1791763200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Uppsala University","id":[{"id":"https:\/\/ror.org\/048a87296","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Epidemiol"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The Swedish Infrastructure for Medical Population-based Life-course and Environmental Research (SIMPLER) is a national research infrastructure that provides longitudinal data and biological samples to investigate how dietary, lifestyle, environmental, and genetic factors influence health and disease across the life course. SIMPLER integrates two population-based prospective cohorts: the Swedish Mammography Cohort and the Cohort of Swedish Men. Baseline data were collected between 1987 and 1990 among 61,433 women and in 1997 among 45,906 men residing in central Sweden. Participants have completed repeated questionnaires on diet, lifestyle, and health approximately every ten years, complemented by linkage to national health registers providing information on diagnoses, mortality, prescribed medications, and socioeconomic status. Two comprehensive subcohorts nested within the cohorts (n\u2009=\u20098046 women, n\u2009=\u20094773 men) provide data from detailed health examinations, questionnaires, and repeated collection of blood, saliva, urine, stool, and adipose tissue biopsy samples. Multi-omics data are available for approximately 12,800 participants, and genomic data for about 51,000 individuals. By integrating long-term questionnaire data, register linkages, and extensive biological sampling, SIMPLER supports research on disease prevention, biomarker discovery, and precision health strategies.<\/jats:p>","DOI":"10.1007\/s10654-026-01455-6","type":"journal-article","created":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T17:08:59Z","timestamp":1791824939000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["SIMPLER: the Swedish infrastructure for medical population-based life-course and environmental research"],"prefix":"10.1007","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0149-452X","authenticated-orcid":false,"given":"Eva","family":"Warensj\u00f6 Lemming","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0933-6451","authenticated-orcid":false,"given":"Frida","family":"Carlsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9680-5772","authenticated-orcid":false,"given":"Diem","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0868-0384","authenticated-orcid":false,"given":"Caesar","family":"Al Jewari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3957-870X","authenticated-orcid":false,"given":"Carl","family":"Brunius","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4421-6466","authenticated-orcid":false,"given":"Liisa","family":"Byberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7713-2373","authenticated-orcid":false,"given":"Lars","family":"Engstrand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4382-4355","authenticated-orcid":false,"given":"Tuulia","family":"Hy\u00f6tylainen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7673-5554","authenticated-orcid":false,"given":"Niclas","family":"H\u00e5kansson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9227-8434","authenticated-orcid":false,"given":"Ingegerd","family":"Johansson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna-Karin","family":"Kolseth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6399-7608","authenticated-orcid":false,"given":"Rikard","family":"Landberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0118-0341","authenticated-orcid":false,"given":"Susanna C.","family":"Larsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1433-0329","authenticated-orcid":false,"given":"Jerzy","family":"Leppert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Mola-Caminal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6811-829X","authenticated-orcid":false,"given":"Erika","family":"Olsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1181-6262","authenticated-orcid":false,"given":"Sergi","family":"Sayols-Baixeras","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9594-4140","authenticated-orcid":false,"given":"Agneta","family":"\u00c5kesson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7387-6845","authenticated-orcid":false,"given":"Alicja","family":"Wolk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2815-1217","authenticated-orcid":false,"given":"Karl","family":"Micha\u00eblsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,10,12]]},"reference":[{"issue":"6","key":"1455_CR1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcpro.2023.100561","volume":"22","author":"M Babu","year":"2023","unstructured":"Babu M, Snyder M. Multi-omics profiling for health. Mol Cell Proteomics. 2023;22(6):100561. https:\/\/doi.org\/10.1016\/j.mcpro.2023.100561.","journal-title":"Mol Cell Proteomics"},{"key":"1455_CR2","doi-asserted-by":"publisher","DOI":"10.13172\/2053-079x-1-2-943","author":"H Harris","year":"2013","unstructured":"Harris H, H\u00e5kansson N, Olofsson C, et al. The Swedish mammography cohort and the cohort of Swedish men: study design and characteristics of two population-based longitudinal cohorts. OA Epidemiol. 2013. https:\/\/doi.org\/10.13172\/2053-079x-1-2-943.","journal-title":"OA Epidemiol"},{"issue":"8","key":"1455_CR3","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1007\/s10654-012-9713-7","volume":"27","author":"A Rosenblad","year":"2012","unstructured":"Rosenblad A, Nilsson G, Leppert J. Intelligence level in late adolescence is inversely associated with BMI change during 22 years of follow-up: results from the WICTORY study. Eur J Epidemiol. 2012;27(8):647\u201355. https:\/\/doi.org\/10.1007\/s10654-012-9713-7.","journal-title":"Eur J Epidemiol"},{"issue":"1","key":"1455_CR4","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1007\/s11136-013-0447-0","volume":"23","author":"J L\u00f6ve","year":"2014","unstructured":"L\u00f6ve J, Andersson L, Moore CD, Hensing G. Psychometric analysis of the Swedish translation of the WHO well-being index. Qual Life Res. 2014;23(1):293\u20137. https:\/\/doi.org\/10.1007\/s11136-013-0447-0.","journal-title":"Qual Life Res"},{"key":"1455_CR5","unstructured":"Livsmedelsverket. Riksmaten-adults 2010\u201311. Food and Nutrient Intake Among Adults in Sweden (Riksmaten-vuxna 2010\u201311. Livsmedels- och n\u00e4ringsintag bland vuxna i Sverige). Uppsala2012."},{"issue":"7","key":"1455_CR6","doi-asserted-by":"publisher","first-page":"1800","DOI":"10.1093\/jn\/134.7.1800","volume":"134","author":"M Messerer","year":"2004","unstructured":"Messerer M, Wolk A, Johansson S-E. The validity of questionnaire-based micronutrient intake estimates is increased by including dietary supplement use in Swedish men. J Nutr. 2004;134(7):1800\u20135. https:\/\/doi.org\/10.1093\/jn\/134.7.1800.","journal-title":"J Nutr"},{"issue":"4 Suppl","key":"1455_CR7","doi-asserted-by":"publisher","first-page":"1220S","DOI":"10.1093\/ajcn\/65.4.1220S","volume":"65","author":"WC Willett","year":"1997","unstructured":"Willett WC, Howe GR, Kushi LH. Adjustment for total energy intake in epidemiologic studies. Am J Clin Nutr. 1997;65(4 Suppl):1220S-S1228. https:\/\/doi.org\/10.1093\/ajcn\/65.4.1220S.","journal-title":"Am J Clin Nutr"},{"issue":"11","key":"1455_CR8","doi-asserted-by":"publisher","first-page":"1748","DOI":"10.1002\/mnfr.201200196","volume":"56","author":"C Bergkvist","year":"2012","unstructured":"Bergkvist C, \u00c5kesson A, Glynn A, et al. Validation of questionnaire-based long-term dietary exposure to polychlorinated biphenyls using biomarkers. Mol Nutr Food Res. 2012;56(11):1748\u201354. https:\/\/doi.org\/10.1002\/mnfr.201200196.","journal-title":"Mol Nutr Food Res"},{"issue":"6","key":"1455_CR9","doi-asserted-by":"publisher","first-page":"1541","DOI":"10.1093\/jn\/134.6.1541","volume":"134","author":"BR Khani","year":"2004","unstructured":"Khani BR, Wolk A, Ye W, Terry P. Reproducibility and validity of major dietary patterns among Swedish women assessed with a food-frequency questionnaire1. J Nutr. 2004;134(6):1541\u20135. https:\/\/doi.org\/10.1093\/jn\/134.6.1541.","journal-title":"J Nutr"},{"issue":"2","key":"1455_CR10","doi-asserted-by":"publisher","first-page":"548","DOI":"10.1093\/ajcn\/85.2.548","volume":"85","author":"EB Levitan","year":"2007","unstructured":"Levitan EB, Westgren CW, Liu S, Wolk A. Reproducibility and validity of dietary glycemic index, dietary glycemic load, and total carbohydrate intake in 141 Swedish men2. Am J Clin Nutr. 2007;85(2):548\u201353. https:\/\/doi.org\/10.1093\/ajcn\/85.2.548.","journal-title":"Am J Clin Nutr"},{"issue":"10","key":"1455_CR11","doi-asserted-by":"publisher","first-page":"1873","DOI":"10.1017\/S000711451200387X","volume":"109","author":"Y Lin","year":"2013","unstructured":"Lin Y, Wolk A, H\u00e5kansson N, et al. Validation of FFQ-based assessment of dietary lignans compared with serum enterolactone in Swedish women. Br J Nutr. 2013;109(10):1873\u201380. https:\/\/doi.org\/10.1017\/S000711451200387X.","journal-title":"Br J Nutr"},{"issue":"10","key":"1455_CR12","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1007\/s10654-008-9273-z","volume":"23","author":"N Orsini","year":"2008","unstructured":"Orsini N, Bellocco R, Bottai M, et al. Validity of self-reported total physical activity questionnaire among older women. Eur J Epidemiol. 2008;23(10):661\u20137. https:\/\/doi.org\/10.1007\/s10654-008-9273-z.","journal-title":"Eur J Epidemiol"},{"issue":"6","key":"1455_CR13","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1007\/s10654-006-9102-1","volume":"22","author":"N Orsini","year":"2007","unstructured":"Orsini N, Bellocco R, Bottai M, Pagano M, Wolk A. Reproducibility of the past year and historical self-administered total physical activity questionnaire among older women. Eur J Epidemiol. 2007;22(6):363\u20138. https:\/\/doi.org\/10.1007\/s10654-006-9102-1.","journal-title":"Eur J Epidemiol"},{"issue":"5","key":"1455_CR14","doi-asserted-by":"publisher","first-page":"1247","DOI":"10.1093\/ajcn\/87.5.1247","volume":"87","author":"S Rautiainen","year":"2008","unstructured":"Rautiainen S, Serafini M, Morgenstern R, Prior RL, Wolk A. The validity and reproducibility of food-frequency questionnaire\u2013based total antioxidant capacity estimates in Swedish women1. Am J Clin Nutr. 2008;87(5):1247\u201353. https:\/\/doi.org\/10.1093\/ajcn\/87.5.1247.","journal-title":"Am J Clin Nutr"},{"issue":"2","key":"1455_CR15","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1007\/s00394-013-0563-1","volume":"53","author":"A Wallin","year":"2014","unstructured":"Wallin A, Di Giuseppe D, Burgaz A, et al. Validity of food frequency questionnaire-based estimates of long-term long-chain n-3 polyunsaturated fatty acid intake. Eur J Nutr. 2014;53(2):549\u201355. https:\/\/doi.org\/10.1007\/s00394-013-0563-1.","journal-title":"Eur J Nutr"},{"issue":"3","key":"1455_CR16","doi-asserted-by":"publisher","first-page":"828","DOI":"10.1093\/jn\/131.3.828","volume":"131","author":"A Wolk","year":"2001","unstructured":"Wolk A, Furuheim M, Vessby B. Fatty acid composition of adipose tissue and serum lipids are valid biological markers of dairy fat intake in men. J Nutr. 2001;131(3):828\u201333. https:\/\/doi.org\/10.1093\/jn\/131.3.828.","journal-title":"J Nutr"},{"issue":"3","key":"1455_CR17","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1038\/sj.ejcn.1600538","volume":"52","author":"A Wolk","year":"1998","unstructured":"Wolk A, Ljung H, Vessby B, Hunter D, Willett W, the Study Group of MS. Effect of additional questions about fat on the validity of fat estimates from a food frequency questionnaire. Eur J Clin Nutr. 1998;52(3):186\u201392. https:\/\/doi.org\/10.1038\/sj.ejcn.1600538.","journal-title":"Eur J Clin Nutr"},{"issue":"2","key":"1455_CR18","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1093\/ajcn\/68.2.291","volume":"68","author":"A Wolk","year":"1998","unstructured":"Wolk A, Vessby B, Ljung H, Barrefors P. Evaluation of a biological marker of dairy fat intake. Am J Clin Nutr. 1998;68(2):291\u20135. https:\/\/doi.org\/10.1093\/ajcn\/68.2.291.","journal-title":"Am J Clin Nutr"},{"key":"1455_CR19","unstructured":"SIMPLER4Health. Questionnaire data collection SMC and COSM. https:\/\/www.simpler4health.se\/w\/sh\/en\/links-and-documents."},{"issue":"7","key":"1455_CR20","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnha.2024.100247","volume":"28","author":"E Warensj\u00f6 Lemming","year":"2024","unstructured":"Warensj\u00f6 Lemming E, Byberg L, H\u00f6ijer J, Larsson SC, Wolk A, Micha\u00eblsson K. Dietary fatty acids and incident hip fractures in cohorts of women and men. A relative validation and follow-up study. J Nutr Health Aging. 2024;28(7):100247. https:\/\/doi.org\/10.1016\/j.jnha.2024.100247","journal-title":"J Nutr Health Aging"},{"issue":"4","key":"1455_CR21","doi-asserted-by":"publisher","first-page":"1083","DOI":"10.1093\/ajcn\/88.4.1083","volume":"88","author":"SC Larsson","year":"2008","unstructured":"Larsson SC, Andersson SO, Johansson JE, Wolk A. Cultured milk, yogurt, and dairy intake in relation to bladder cancer risk in a prospective study of Swedish women and men. Am J Clin Nutr. 2008;88(4):1083\u20137. https:\/\/doi.org\/10.1093\/ajcn\/88.4.1083.","journal-title":"Am J Clin Nutr"},{"issue":"1","key":"1455_CR22","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1093\/ajcn\/70.1.21","volume":"70","author":"J Jiang","year":"1999","unstructured":"Jiang J, Wolk A, Vessby B. Relation between the intake of milk fat and the occurrence of conjugated linoleic acid in human adipose tissue. Am J Clin Nutr. 1999;70(1):21\u20137. https:\/\/doi.org\/10.1093\/ajcn\/70.1.21.","journal-title":"Am J Clin Nutr"},{"key":"1455_CR23","doi-asserted-by":"publisher","first-page":"g6015","DOI":"10.1136\/bmj.g6015","volume":"349","author":"K Micha\u00eblsson","year":"2014","unstructured":"Micha\u00eblsson K, Wolk A, Langenskiold S, et al. Milk intake and risk of mortality and fractures in women and men: cohort studies. BMJ. 2014;349:g6015. . https:\/\/doi.org\/10.1136\/bmj.g6015","journal-title":"BMJ"},{"issue":"3","key":"1455_CR24","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1017\/s1041610295002171","volume":"7","author":"M Gatz","year":"1995","unstructured":"Gatz M, Reynolds C, Nikolic J, Lowe B, Karel M, Pedersen N. An empirical test of telephone screening to identify potential dementia cases. Int Psychogeriatr. 1995;7(3):429\u201338. https:\/\/doi.org\/10.1017\/s1041610295002171.","journal-title":"Int Psychogeriatr"},{"issue":"3","key":"1455_CR25","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1016\/0022-3956(75)90026-6","volume":"12","author":"MF Folstein","year":"1975","unstructured":"Folstein MF, Folstein SE, McHugh PR. \u201cMini-mental state\u201d: a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975;12(3):189\u201398. https:\/\/doi.org\/10.1016\/0022-3956(75)90026-6.","journal-title":"J Psychiatr Res"},{"key":"1455_CR26","unstructured":"National guidelines for pre-analysis handling of liquid-based samples for reserach (Nationella riktlinjer f\u00f6r preanalytisk hantering av v\u00e4tskebaserade prov f\u00f6r forskning). Stockholm 2020. https:\/\/biobanksverige.se\/wp-content\/uploads\/2020\/05\/y2-nationella-riktlinjer-for-preanalytisk-hantering-av-vatskebaserade-prov-for-forskning.pdf"},{"key":"1455_CR27","first-page":"37","volume":"329","author":"D Anderson","year":"1995","unstructured":"Anderson D, Basaran N, Blowers SD, Edwards AJ. The effect of antioxidants on bleomycin treatment in in vitro and in vivo genotoxicity assays. Mutat Res. 1995;329:37\u201347.","journal-title":"Mutat Res"},{"issue":"1","key":"1455_CR28","doi-asserted-by":"publisher","DOI":"10.1186\/s12967-024-05383-5","volume":"22","author":"M Graham","year":"2024","unstructured":"Graham M, Samuel G, Farley M. Roadmap for low-carbon ultra-low temperature storage in biobanking. J Transl Med. 2024;22(1):747. https:\/\/doi.org\/10.1186\/s12967-024-05383-5.","journal-title":"J Transl Med"},{"issue":"5","key":"1455_CR29","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1042\/cs0680581","volume":"68","author":"M Boberg","year":"1985","unstructured":"Boberg M, Croon LB, Gustafsson IB, Vessby B. Platelet fatty acid composition in relation to fatty acid composition in plasma and to serum lipoprotein lipids in healthy subjects with special reference to the linoleic acid pathway. Clin Sci (London, England\u202f: 1979). 1985;68(5):581\u20137. https:\/\/doi.org\/10.1042\/cs0680581.","journal-title":"Clin Sci (London, England : 1979)"},{"issue":"3","key":"1455_CR30","doi-asserted-by":"publisher","first-page":"540","DOI":"10.1038\/s41588-026-02512-2","volume":"58","author":"KF Dekkers","year":"2026","unstructured":"Dekkers KF, Pertiwi K, Baldanzi G, et al. Genome-wide association analyses highlight the role of the intestinal molecular environment in human gut microbiota variation. Nat Genet. 2026;58(3):540\u20139. https:\/\/doi.org\/10.1038\/s41588-026-02512-2.","journal-title":"Nat Genet"},{"issue":"1","key":"1455_CR31","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1158\/1055-9965.EPI-16-0106","volume":"26","author":"CI Amos","year":"2017","unstructured":"Amos CI, Dennis J, Wang Z, et al. The OncoArray Consortium: a network for understanding the genetic architecture of common cancers. Cancer Epidemiol Biomarkers Prev. 2017;26(1):126\u201335. https:\/\/doi.org\/10.1158\/1055-9965.EPI-16-0106.","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"issue":"7678","key":"1455_CR32","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1038\/nature24284","volume":"551","author":"K Michailidou","year":"2017","unstructured":"Michailidou K, Lindstr\u00f6m S, Dennis J, et al. Association analysis identifies 65 new breast cancer risk loci. Nature. 2017;551(7678):92\u20134. . https:\/\/doi.org\/10.1038\/nature24284","journal-title":"Nature"},{"issue":"4","key":"1455_CR33","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1111\/j.1365-2796.2011.02509.x","volume":"271","author":"KL Bolton","year":"2012","unstructured":"Bolton KL, Ganda C, Berchuck A, Pharaoh PD, Gayther SA. Role of common genetic variants in ovarian cancer susceptibility and outcome: progress to date from the Ovarian Cancer Association Consortium (OCAC). J Intern Med. 2012;271(4):366\u201378. https:\/\/doi.org\/10.1111\/j.1365-2796.2011.02509.x.","journal-title":"J Intern Med"},{"issue":"2","key":"1455_CR34","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1093\/jnci\/djy099","volume":"111","author":"SL Schmit","year":"2019","unstructured":"Schmit SL, Edlund CK, Schumacher FR, et al. Novel common genetic susceptibility loci for colorectal cancer. J Natl Cancer Inst. 2019;111(2):146\u201357. https:\/\/doi.org\/10.1093\/jnci\/djy099.","journal-title":"J Natl Cancer Inst"},{"issue":"7","key":"1455_CR35","doi-asserted-by":"publisher","first-page":"1121","DOI":"10.1158\/1055-9965.EPI-14-0317","volume":"24","author":"A Amin Al Olama","year":"2015","unstructured":"Amin Al Olama A, Benlloch S, Antoniou AC, et al. Risk analysis of prostate cancer in PRACTICAL, a multinational consortium, using 25 known prostate cancer susceptibility loci. Cancer Epidemiol Biomarkers Prev. 2015;24(7):1121\u20139. https:\/\/doi.org\/10.1158\/1055-9965.EPI-14-0317.","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"1455_CR36","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2025.105580","volume":"113","author":"K Micha\u00eblsson","year":"2025","unstructured":"Micha\u00eblsson K, Zheng R, Baron JA, et al. Cardio-metabolic-related plasma proteins reveal biological links between cardiovascular diseases and fragility fractures: a cohort and Mendelian randomisation investigation. EBioMedicine. 2025;113:105580. https:\/\/doi.org\/10.1016\/j.ebiom.2025.105580.","journal-title":"EBioMedicine"},{"issue":"1","key":"1455_CR37","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.201800384","volume":"63","author":"MM Ulaszewska","year":"2019","unstructured":"Ulaszewska MM, Weinert CH, Trimigno A, et al. Nutrimetabolomics: an integrative action for metabolomic analyses in human nutritional studies. Mol Nutr Food Res. 2019;63(1):e1800384. https:\/\/doi.org\/10.1002\/mnfr.201800384.","journal-title":"Mol Nutr Food Res"},{"key":"1455_CR38","doi-asserted-by":"publisher","DOI":"10.3390\/metabo10040135","author":"A Kl\u00e5vus","year":"2020","unstructured":"Kl\u00e5vus A, Kokla M, Noerman S, et al. \"notame\": workflow for non-targeted LC-MS metabolic profiling. Metabolites. 2020. . https:\/\/doi.org\/10.3390\/metabo10040135","journal-title":"Metabolites"},{"issue":"1","key":"1455_CR39","doi-asserted-by":"publisher","first-page":"604","DOI":"10.1038\/s41467-023-36231-7","volume":"14","author":"H Julkunen","year":"2023","unstructured":"Julkunen H, Cichonska A, Tiainen M, et al. Atlas of plasma NMR biomarkers for health and disease in 118,461 individuals from the UK Biobank. Nat Commun. 2023;14(1):604. https:\/\/doi.org\/10.1038\/s41467-023-36231-7.","journal-title":"Nat Commun"},{"key":"1455_CR40","doi-asserted-by":"publisher","DOI":"10.3390\/nu12113586","author":"D Djekic","year":"2020","unstructured":"Djekic D, Shi L, Calais F, et al. Effects of a lacto-ovo-vegetarian diet on the plasma lipidome and its association with atherosclerotic burden in patients with coronary artery disease-a randomized, open-label, cross-over study. Nutrients. 2020. https:\/\/doi.org\/10.3390\/nu12113586.","journal-title":"Nutrients"},{"key":"1455_CR41","unstructured":"Boulund F. StaG-mwc v0.5.1. Zenodo; 2018."},{"issue":"D1","key":"1455_CR42","doi-asserted-by":"publisher","first-page":"D785","DOI":"10.1093\/nar\/gkab776","volume":"50","author":"DH Parks","year":"2022","unstructured":"Parks DH, Chuvochina M, Rinke C, Mussig AJ, Chaumeil PA, Hugenholtz P. GTDB: an ongoing census of bacterial and archaeal diversity through a phylogenetically consistent, rank normalized and complete genome-based taxonomy. Nucleic Acids Res. 2022;50(D1):D785\u201394. https:\/\/doi.org\/10.1093\/nar\/gkab776.","journal-title":"Nucleic Acids Res"},{"key":"1455_CR43","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2024.1425489","volume":"15","author":"S Pita","year":"2024","unstructured":"Pita S, Myers PN, Johansen J, et al. CHAMP delivers accurate taxonomic profiles of the prokaryotes, eukaryotes, and bacteriophages in the human microbiome. Front Microbiol. 2024;15:1425489. https:\/\/doi.org\/10.3389\/fmicb.2024.1425489.","journal-title":"Front Microbiol"},{"key":"1455_CR44","doi-asserted-by":"publisher","DOI":"10.3389\/froh.2025.1709163","volume":"6","author":"A Esberg","year":"2025","unstructured":"Esberg A, Haworth S, Johansson I. Oral microbiota in an aging Swedish population with high dental disease burden: an observational registry-based study. Front Oral Health. 2025;6:1709163. https:\/\/doi.org\/10.3389\/froh.2025.1709163.","journal-title":"Front Oral Health"},{"issue":"3","key":"1455_CR45","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1007\/s10552-005-0455-7","volume":"17","author":"JM Genkinger","year":"2006","unstructured":"Genkinger JM, Hunter DJ, Spiegelman D, et al. A pooled analysis of 12 cohort studies of dietary fat, cholesterol and egg intake and ovarian cancer. Cancer Causes Control\u202f: CCC. 2006;17(3):273\u201385. https:\/\/doi.org\/10.1007\/s10552-005-0455-7.","journal-title":"Cancer Causes Control : CCC"},{"issue":"6","key":"1455_CR46","doi-asserted-by":"publisher","first-page":"1106","DOI":"10.1093\/annonc\/mdu019","volume":"25","author":"JM Genkinger","year":"2014","unstructured":"Genkinger JM, Wang M, Li R, et al. Dairy products and pancreatic cancer risk: a pooled analysis of 14 cohort studies. Ann Oncol. 2014;25(6):1106\u201315. https:\/\/doi.org\/10.1093\/annonc\/mdu019.","journal-title":"Ann Oncol"},{"issue":"23","key":"1455_CR47","doi-asserted-by":"publisher","first-page":"1695","DOI":"10.1093\/jnci\/djn386","volume":"100","author":"JE Lee","year":"2008","unstructured":"Lee JE, Spiegelman D, Hunter DJ, et al. Fat, protein, and meat consumption and renal cell cancer risk: a pooled analysis of 13 prospective studies. J Natl Cancer Inst. 2008;100(23):1695\u2013706. https:\/\/doi.org\/10.1093\/jnci\/djn386.","journal-title":"J Natl Cancer Inst"},{"issue":"5","key":"1455_CR48","doi-asserted-by":"publisher","first-page":"767","DOI":"10.1002\/1097-0215(20010601)92:5<767::aid-ijc1247>3.0.co;2-0","volume":"92","author":"SA Smith-Warner","year":"2001","unstructured":"Smith-Warner SA, Spiegelman D, Adami HO, et al. Types of dietary fat and breast cancer: a pooled analysis of cohort studies. Int J Cancer. 2001;92(5):767\u201374. https:\/\/doi.org\/10.1002\/1097-0215(20010601)92:5%3c767::aid-ijc1247%3e3.0.co;2-0.","journal-title":"Int J Cancer"},{"key":"1455_CR49","doi-asserted-by":"publisher","DOI":"10.1200\/jco.23.01101","author":"IR Timmins","year":"2023","unstructured":"Timmins IR, Jones ME, O\u2019Brien KM, et al. International pooled analysis of leisure-time physical activity and premenopausal breast cancer in women from 19 cohorts. J Clin Oncol. 2023. https:\/\/doi.org\/10.1200\/jco.23.01101.","journal-title":"J Clin Oncol"},{"issue":"3","key":"1455_CR50","doi-asserted-by":"publisher","first-page":"e73","DOI":"10.1093\/ije\/dyab211","volume":"51","author":"MK Townsend","year":"2022","unstructured":"Townsend MK, Trabert B, Fortner RT, et al. Cohort profile: the ovarian cancer cohort consortium (OC3). Int J Epidemiol. 2022;51(3):e73-86. https:\/\/doi.org\/10.1093\/ije\/dyab211.","journal-title":"Int J Epidemiol"},{"issue":"7","key":"1455_CR51","doi-asserted-by":"publisher","first-page":"1591","DOI":"10.1007\/s00198-018-4517-6","volume":"29","author":"V Benetou","year":"2018","unstructured":"Benetou V, Orfanos P, Feskanich D, et al. Mediterranean diet and hip fracture incidence among older adults: the CHANCES project. Osteoporos Int. 2018;29(7):1591\u20139. https:\/\/doi.org\/10.1007\/s00198-018-4517-6.","journal-title":"Osteoporos Int"},{"issue":"2","key":"1455_CR52","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1093\/ajcn\/nqy272","volume":"109","author":"D Karasik","year":"2019","unstructured":"Karasik D, Zillikens MC, Hsu YH, et al. Disentangling the genetics of lean mass. Am J Clin Nutr. 2019;109(2):276\u201387. https:\/\/doi.org\/10.1093\/ajcn\/nqy272.","journal-title":"Am J Clin Nutr"},{"issue":"3","key":"1455_CR53","doi-asserted-by":"publisher","first-page":"530","DOI":"10.1038\/s41588-026-02502-4","volume":"58","author":"MR Moksnes","year":"2026","unstructured":"Moksnes MR, Coward E, Nethander M, et al. The HUNT study identifies host genetic factors reproducibly associated with human gut microbiota composition. Nat Genet. 2026;58(3):530\u20139. https:\/\/doi.org\/10.1038\/s41588-026-02502-4.","journal-title":"Nat Genet"},{"issue":"4","key":"1455_CR54","doi-asserted-by":"publisher","DOI":"10.1289\/EHP7404","volume":"129","author":"E Helte","year":"2021","unstructured":"Helte E, Donat Vargas C, Kippler M, Wolk A, Micha\u00eblsson K, \u00c5kesson A. Fluoride in drinking water, diet, and urine in relation to bone mineral density and fracture incidence in postmenopausal women. Environ Health Perspect. 2021;129(4):47005. https:\/\/doi.org\/10.1289\/EHP7404","journal-title":"Environ Health Perspect"},{"issue":"6","key":"1455_CR55","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1136\/thoraxjnl-2015-207851","volume":"72","author":"J Kaluza","year":"2017","unstructured":"Kaluza J, Larsson SC, Orsini N, Linden A, Wolk A. Fruit and vegetable consumption and risk of COPD: a prospective cohort study of men. Thorax. 2017;72(6):500\u20139. https:\/\/doi.org\/10.1136\/thoraxjnl-2015-207851.","journal-title":"Thorax"},{"issue":"5","key":"1455_CR56","doi-asserted-by":"publisher","first-page":"562","DOI":"10.1016\/j.jsams.2018.11.020","volume":"22","author":"SC Larsson","year":"2019","unstructured":"Larsson SC, Wolk A. Sedentary leisure-time in relation to mortality and survival time. J Sci Med Sport. 2019;22(5):562\u20137. https:\/\/doi.org\/10.1016\/j.jsams.2018.11.020.","journal-title":"J Sci Med Sport"},{"key":"1455_CR57","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/j.nut.2018.04.006","volume":"54","author":"F Stilling","year":"2018","unstructured":"Stilling F, Wolk A, Religa D, et al. Adipose tissue fatty acid composition and cognitive impairment. Nutrition. 2018;54:153\u20137. https:\/\/doi.org\/10.1016\/j.nut.2018.04.006.","journal-title":"Nutrition"},{"issue":"6","key":"1455_CR58","doi-asserted-by":"publisher","first-page":"4161","DOI":"10.1016\/j.clnu.2021.01.043","volume":"40","author":"E Warensj\u00f6 Lemming","year":"2021","unstructured":"Warensj\u00f6 Lemming E, Byberg L, H\u00f6ijer J, Larsson SC, Wolk A, Micha\u00eblsson K. Combinations of dietary calcium intake and Mediterranean-style diet on risk of hip fracture: a longitudinal cohort study of 82,000 women and men. Clin Nutr. 2021;40(6):4161\u201370. https:\/\/doi.org\/10.1016\/j.clnu.2021.01.043","journal-title":"Clin Nutr"},{"issue":"9","key":"1455_CR59","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1003331","volume":"17","author":"K Micha\u00eblsson","year":"2020","unstructured":"Micha\u00eblsson K, Baron JA, Byberg L, et al. Combined associations of body mass index and adherence to a Mediterranean-like diet with all-cause and cardiovascular mortality: a cohort study. PLoS Med. 2020;17(9):e1003331. https:\/\/doi.org\/10.1371\/journal.pmed.1003331.","journal-title":"PLoS Med"},{"issue":"11","key":"1455_CR60","doi-asserted-by":"publisher","first-page":"1043","DOI":"10.1038\/s41366-023-01351-z","volume":"47","author":"OE Titova","year":"2023","unstructured":"Titova OE, Brunius C, Warensj\u00f6 Lemming E, et al. Comprehensive analyses of circulating cardiometabolic proteins and objective measures of fat mass. Int J Obes (Lond). 2023;47(11):1043\u20139. . https:\/\/doi.org\/10.1038\/s41366-023-01351-z","journal-title":"Int J Obes (Lond)"},{"issue":"6","key":"1455_CR61","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCGEN.123.004233","volume":"16","author":"L Lind","year":"2023","unstructured":"Lind L, Titova O, Zeng R, et al. Plasma protein profiling of incident cardiovascular diseases: a multisample evaluation. Circ Genom Precis Med. 2023;16(6):e004233. https:\/\/doi.org\/10.1161\/CIRCGEN.123.004233.","journal-title":"Circ Genom Precis Med"},{"issue":"11","key":"1455_CR62","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.118.011860","volume":"8","author":"E Warensj\u00f6 Lemming","year":"2019","unstructured":"Warensj\u00f6 Lemming E, Byberg L, Stattin K, et al. Dietary pattern specific protein biomarkers for cardiovascular disease: a cross-sectional study in 2 independent cohorts. J Am Heart Assoc. 2019;8(11):e011860. . https:\/\/doi.org\/10.1161\/JAHA.118.011860","journal-title":"J Am Heart Assoc"},{"issue":"5","key":"1455_CR63","doi-asserted-by":"publisher","first-page":"1819","DOI":"10.1007\/s00394-024-03385-z","volume":"63","author":"E Warensj\u00f6 Lemming","year":"2024","unstructured":"Warensj\u00f6 Lemming E, Byberg L, H\u00f6ijer J, Baron JA, Wolk A, Micha\u00eblsson K. Meat consumption and the risk of hip fracture in women and men: two prospective Swedish cohort studies. Eur J Nutr. 2024;63(5):1819\u201333. https:\/\/doi.org\/10.1007\/s00394-024-03385-z","journal-title":"Eur J Nutr"},{"issue":"17","key":"1455_CR64","doi-asserted-by":"publisher","first-page":"1865","DOI":"10.1177\/2047487319868033","volume":"26","author":"K Stattin","year":"2019","unstructured":"Stattin K, Lind L, Elmst\u00e5hl S, et al. Physical activity is associated with a large number of cardiovascular-specific proteins: cross-sectional analyses in two independent cohorts. Eur J Prev Cardiol. 2019;26(17):1865\u201373. . https:\/\/doi.org\/10.1177\/2047487319868033","journal-title":"Eur J Prev Cardiol"},{"issue":"4","key":"1455_CR65","doi-asserted-by":"publisher","first-page":"1351","DOI":"10.1038\/s41591-026-04284-y","volume":"32","author":"G Baldanzi","year":"2026","unstructured":"Baldanzi G, Larsson A, Sayols-Baixeras S, et al. Antibiotic use and gut microbiome composition links from individual-level prescription data of 14,979 individuals. Nat Med. 2026;32(4):1351\u201361. https:\/\/doi.org\/10.1038\/s41591-026-04284-y.","journal-title":"Nat Med"},{"issue":"4","key":"1455_CR66","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1007\/s10654-024-01119-3","volume":"39","author":"AA Matthews","year":"2024","unstructured":"Matthews AA, Dahebreh IJ, MacDonald CJ, et al. Prospective benchmarking of an observational analysis in the SWEDEHEART registry against the REDUCE-AMI randomized trial. Eur J Epidemiol. 2024;39(4):349\u201361. https:\/\/doi.org\/10.1007\/s10654-024-01119-3.","journal-title":"Eur J Epidemiol"},{"key":"1455_CR67","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/j.bone.2018.10.011","volume":"126","author":"SC Larsson","year":"2019","unstructured":"Larsson SC, Micha\u00eblsson K, Burgess S. Mendelian randomization in the bone field. Bone. 2019;126:51\u20138. https:\/\/doi.org\/10.1016\/j.bone.2018.10.011.","journal-title":"Bone"},{"key":"1455_CR68","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2022.155329","volume":"137","author":"SC Larsson","year":"2022","unstructured":"Larsson SC, Michalsson K, Mola-Caminal M, H\u00f6ijer J, Mantzoros CS. Genome-wide association and Mendelian randomization study of fibroblast growth factor 21 reveals causal associations with hyperlipidemia and possibly NASH. Metabolism. 2022;137:155329. . https:\/\/doi.org\/10.1016\/j.metabol.2022.155329","journal-title":"Metabolism"},{"issue":"1","key":"1455_CR69","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1093\/aje\/kwad181","volume":"193","author":"DB Ibsen","year":"2024","unstructured":"Ibsen DB, Chiu YH, Gemes K, Wolk A. Hypothetical 22-year intervention with the dietary approaches to stop hypertension and risk of heart failure in a general population. Am J Epidemiol. 2024;193(1):96\u2013106. https:\/\/doi.org\/10.1093\/aje\/kwad181.","journal-title":"Am J Epidemiol"},{"issue":"1","key":"1455_CR70","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1093\/ije\/dyaa239","volume":"50","author":"A Mitchell","year":"2021","unstructured":"Mitchell A, Fall T, Melhus H, Wolk A, Micha\u00eblsson K, Byberg L. Is the effect of Mediterranean diet on hip fracture mediated through type 2 diabetes mellitus and body mass index? Int J Epidemiol. 2021;50(1):234\u201344. . https:\/\/doi.org\/10.1093\/ije\/dyaa239","journal-title":"Int J Epidemiol"},{"issue":"2","key":"1455_CR71","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1111\/joim.12995","volume":"287","author":"C Donat-Vargas","year":"2020","unstructured":"Donat-Vargas C, Bellavia A, Berglund M, Glynn A, Wolk A, \u00c5kesson A. Cardiovascular and cancer mortality in relation to dietary polychlorinated biphenyls and marine polyunsaturated fatty acids: a nutritional-toxicological aspect of fish consumption. J Intern Med. 2020;287(2):197\u2013209. https:\/\/doi.org\/10.1111\/joim.12995.","journal-title":"J Intern Med"},{"issue":"5","key":"1455_CR72","doi-asserted-by":"publisher","first-page":"1231","DOI":"10.1093\/jn\/nxaa447","volume":"151","author":"M Pearce","year":"2021","unstructured":"Pearce M, Fanidi A, Bishop TRP, et al. Associations of total legume, pulse, and soy consumption with incident type 2 diabetes: federated meta-analysis of 27 studies from diverse world regions. J Nutr. 2021;151(5):1231\u201340. https:\/\/doi.org\/10.1093\/jn\/nxaa447.","journal-title":"J Nutr"},{"key":"1455_CR73","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.envint.2019.01.069","volume":"126","author":"A \u00c5kesson","year":"2019","unstructured":"\u00c5kesson A, Donat-Vargas C, Berglund M, Glynn A, Wolk A, Kippler M. Dietary exposure to polychlorinated biphenyls and risk of heart failure - a population-based prospective cohort study. Environ Int. 2019;126:1\u20136. https:\/\/doi.org\/10.1016\/j.envint.2019.01.069.","journal-title":"Environ Int"},{"issue":"9","key":"1455_CR74","doi-asserted-by":"publisher","first-page":"e2333347","DOI":"10.1001\/jamanetworkopen.2023.33347","volume":"6","author":"C Donat-Vargas","year":"2023","unstructured":"Donat-Vargas C, Schillemans T, Kiviranta H, et al. Blood levels of organochlorine contaminants mixtures and cardiovascular disease. JAMA Netw Open. 2023;6(9):e2333347. https:\/\/doi.org\/10.1001\/jamanetworkopen.2023.33347.","journal-title":"JAMA Netw Open"},{"issue":"4","key":"1455_CR75","doi-asserted-by":"publisher","first-page":"1091","DOI":"10.1093\/ajcn\/nqac186","volume":"116","author":"E Helte","year":"2022","unstructured":"Helte E, S\u00e4ve-S\u00f6derbergh M, Larsson SC, \u00c5kesson A. Calcium and magnesium in drinking water and risk of myocardial infarction and stroke-a population-based cohort study. Am J Clin Nutr. 2022;116(4):1091\u2013100. https:\/\/doi.org\/10.1093\/ajcn\/nqac186","journal-title":"Am J Clin Nutr"},{"issue":"12","key":"1455_CR76","doi-asserted-by":"publisher","first-page":"1597","DOI":"10.1093\/jnci\/djad145","volume":"115","author":"E Helte","year":"2023","unstructured":"Helte E, S\u00e4ve-S\u00f6derbergh M, Larsson SC, Martling A, \u00c5kesson A. Disinfection by-products in drinking water and risk of colorectal cancer: a population-based cohort study. J Natl Cancer Inst. 2023;115(12):1597\u2013604. https:\/\/doi.org\/10.1093\/jnci\/djad145","journal-title":"J Natl Cancer Inst"},{"issue":"7","key":"1455_CR77","doi-asserted-by":"publisher","first-page":"1601","DOI":"10.1002\/jbmr.386","volume":"26","author":"LD Thomas","year":"2011","unstructured":"Thomas LD, Micha\u00eblsson K, Julin B, Wolk A, Akesson A. Dietary cadmium exposure and fracture incidence among men: a population-based prospective cohort study. J Bone Miner Res. 2011;26(7):1601\u20138. https:\/\/doi.org\/10.1002\/jbmr.386","journal-title":"J Bone Miner Res"},{"key":"1455_CR78","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2022.107114","volume":"161","author":"J Tagt","year":"2022","unstructured":"Tagt J, Helte E, Donat-Vargas C, et al. Long-term cadmium exposure and fractures, cardiovascular disease, and mortality in a prospective cohort of women. Environ Int. 2022;161:107114. https:\/\/doi.org\/10.1016\/j.envint.2022.107114.","journal-title":"Environ Int"},{"key":"1455_CR79","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2024.108878","volume":"190","author":"L Stucki","year":"2024","unstructured":"Stucki L, Helte E, Axelsson O, et al. Long-term exposure to air pollution, road traffic noise and greenness, and incidence of myocardial infarction in women. Environ Int. 2024;190:108878. https:\/\/doi.org\/10.1016\/j.envint.2024.108878.","journal-title":"Environ Int"},{"issue":"2","key":"1455_CR80","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1003889","volume":"19","author":"LT Fadnes","year":"2022","unstructured":"Fadnes LT, \u00d8kland JM, Haaland \u00d8A, Johansson KA. Estimating impact of food choices on life expectancy: a modeling study. PLoS Med. 2022;19(2):e1003889. https:\/\/doi.org\/10.1371\/journal.pmed.1003889.","journal-title":"PLoS Med"},{"issue":"6","key":"1455_CR81","doi-asserted-by":"publisher","first-page":"898","DOI":"10.1093\/aje\/kwt062","volume":"178","author":"H Hallstr\u00f6m","year":"2013","unstructured":"Hallstr\u00f6m H, Byberg L, Glynn A, Lemming EW, Wolk A, Micha\u00eblsson K. Long-term coffee consumption in relation to fracture risk and bone mineral density in women. Am J Epidemiol. 2013;178(6):898\u2013909. . https:\/\/doi.org\/10.1093\/aje\/kwt062","journal-title":"Am J Epidemiol"},{"issue":"13","key":"1455_CR82","doi-asserted-by":"publisher","first-page":"1017","DOI":"10.1136\/heartjnl-2015-309203","volume":"102","author":"SC Larsson","year":"2016","unstructured":"Larsson SC, \u00c5kesson A, Gigante B, Wolk A. Chocolate consumption and risk of myocardial infarction: a prospective study and meta-analysis. Heart. 2016;102(13):1017\u201322. https:\/\/doi.org\/10.1136\/heartjnl-2015-309203.","journal-title":"Heart"},{"issue":"5","key":"1455_CR83","doi-asserted-by":"publisher","first-page":"1171","DOI":"10.1093\/ajcn\/84.5.1171","volume":"84","author":"SC Larsson","year":"2006","unstructured":"Larsson SC, Bergkvist L, Wolk A. Consumption of sugar and sugar-sweetened foods and the risk of pancreatic cancer in a prospective study. Am J Clin Nutr. 2006;84(5):1171\u20136. https:\/\/doi.org\/10.1093\/ajcn\/84.5.1171.","journal-title":"Am J Clin Nutr"},{"issue":"4","key":"1455_CR84","doi-asserted-by":"publisher","first-page":"986","DOI":"10.1161\/STROKEAHA.116.012675","volume":"47","author":"SC Larsson","year":"2016","unstructured":"Larsson SC, Wallin A, Wolk A. Dietary approaches to stop hypertension diet and incidence of stroke: results from 2 prospective cohorts. Stroke. 2016;47(4):986\u201390. https:\/\/doi.org\/10.1161\/STROKEAHA.116.012675.","journal-title":"Stroke"},{"issue":"2","key":"1455_CR85","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1016\/j.clnu.2016.01.019","volume":"36","author":"SC Larsson","year":"2017","unstructured":"Larsson SC, Wolk A. Fish, long-chain omega-3 polyunsaturated fatty acid intake and incidence of atrial fibrillation: a pooled analysis of two prospective studies. Clin Nutr. 2017;36(2):537\u201341. https:\/\/doi.org\/10.1016\/j.clnu.2016.01.019.","journal-title":"Clin Nutr"},{"issue":"8","key":"1455_CR86","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1161\/Circulationaha.112.000728","volume":"128","author":"O Stackelberg","year":"2013","unstructured":"Stackelberg O, Bj\u00f6rck M, Larsson SC, Orsini N, Wolk A. Fruit and vegetable consumption with risk of abdominal aortic aneurysm. Circulation. 2013;128(8):795\u2013802. https:\/\/doi.org\/10.1161\/Circulationaha.112.000728.","journal-title":"Circulation"},{"issue":"6","key":"1455_CR87","doi-asserted-by":"publisher","first-page":"1204","DOI":"10.1007\/s00125-016-3923-6","volume":"59","author":"A Wallin","year":"2016","unstructured":"Wallin A, Forouhi NG, Wolk A, Larsson SC. Egg consumption and risk of type 2 diabetes: a prospective study and dose-response meta-analysis. Diabetologia. 2016;59(6):1204\u201313. https:\/\/doi.org\/10.1007\/s00125-016-3923-6.","journal-title":"Diabetologia"},{"issue":"11","key":"1455_CR88","doi-asserted-by":"publisher","first-page":"1801","DOI":"10.1016\/j.jand.2019.06.010","volume":"119","author":"SI Kirkpatrick","year":"2019","unstructured":"Kirkpatrick SI, Baranowski T, Subar AF, Tooze JA, Frongillo EA. Best practices for conducting and interpreting studies to validate self-report dietary assessment methods. J Acad Nutr Diet. 2019;119(11):1801\u201316. https:\/\/doi.org\/10.1016\/j.jand.2019.06.010.","journal-title":"J Acad Nutr Diet"},{"issue":"10","key":"1455_CR89","doi-asserted-by":"publisher","first-page":"1933","DOI":"10.1017\/S1368980018000484","volume":"21","author":"HX Wu","year":"2018","unstructured":"Wu HX, Omar NAM, H\u00e5kansson N, Wolk A, Micha\u00eblsson K, Landberg R. Evaluation of alkylresorcinols in adipose tissue biopsies as a long-term biomarker of whole-grain wheat and rye intake in free-living Swedish men and women. Public Health Nutr. 2018;21(10):1933\u201342. https:\/\/doi.org\/10.1017\/S1368980018000484.","journal-title":"Public Health Nutr"},{"issue":"4","key":"1455_CR90","doi-asserted-by":"publisher","first-page":"408","DOI":"10.1111\/joim.13596","volume":"293","author":"S Noerman","year":"2023","unstructured":"Noerman S, Landberg R. Blood metabolite profiles linking dietary patterns with health-toward precision nutrition. J Intern Med. 2023;293(4):408\u201332. https:\/\/doi.org\/10.1111\/joim.13596.","journal-title":"J Intern Med"},{"issue":"2","key":"1455_CR91","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1016\/j.ajcnut.2023.10.016","volume":"119","author":"MC Playdon","year":"2024","unstructured":"Playdon MC, Tinker LF, Prentice RL, et al. Measuring diet by metabolomics: a 14-d controlled feeding study of weighed food intake. Am J Clin Nutr. 2024;119(2):511\u201326. https:\/\/doi.org\/10.1016\/j.ajcnut.2023.10.016.","journal-title":"Am J Clin Nutr"},{"key":"1455_CR92","doi-asserted-by":"publisher","DOI":"10.1177\/14034948251405687","author":"LM Loennberg","year":"2026","unstructured":"Loennberg LM, Chabok A, Ohrvik J, Rehn M, Leppert J, Damberg M. Swedish snus use in non-smoking middle-aged men and risk of cardiovascular disease: a population-based cohort study with 27-year follow-up. Scand J Public Health. 2026. https:\/\/doi.org\/10.1177\/14034948251405687.","journal-title":"Scand J Public Health"},{"key":"1455_CR93","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyaf004","author":"F Sp\u00e4th","year":"2025","unstructured":"Sp\u00e4th F, Wennberg P, Johansson R, et al. Cohort profile: the Northern Sweden health and disease study (NSHDS). Int J Epidemiol. 2025. https:\/\/doi.org\/10.1093\/ije\/dyaf004.","journal-title":"Int J Epidemiol"}],"container-title":["European Journal of Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10654-026-01455-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10654-026-01455-6","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10654-026-01455-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T00:03:22Z","timestamp":1791849802000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10654-026-01455-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,12]]},"references-count":93,"alternative-id":["1455"],"URL":"https:\/\/doi.org\/10.1007\/s10654-026-01455-6","relation":{},"ISSN":["0393-2990","1573-7284"],"issn-type":[{"value":"0393-2990","type":"print"},{"value":"1573-7284","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,12]]},"assertion":[{"value":"5 March 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 August 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 October 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors have no relevant financial or non-financial interests to disclose.","order":1,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study is performed in line with the principles of the Declaration of Helsinki. More than 100 ethical approvals have been obtained over the years, initially from regional ethics committees and, since 2019, from the national Swedish Ethical Review Authority.","order":2,"name":"Ethics","label":"Ethical approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"For SMC and COSM, participant consent was structured such that completion and return of the questionnaire constituted written informed consent. The completion of the questionnaire was preceded by a two-page information sheet about the study\u2019s purposes and data responsibility. For SMCC and COSMC, each participant provided written informed consent on a separate form at each visit.","order":3,"name":"Ethics","label":"Consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}}]}}