{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T11:03:09Z","timestamp":1785927789560,"version":"3.56.0"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,12,17]],"date-time":"2022-12-17T00:00:00Z","timestamp":1671235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,12,17]],"date-time":"2022-12-17T00:00:00Z","timestamp":1671235200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2013\/22581-5"],"award-info":[{"award-number":["2013\/22581-5"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["88882365161-001"],"award-info":[{"award-number":["88882365161-001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Environ Monit Assess"],"published-print":{"date-parts":[[2023,1]]},"DOI":"10.1007\/s10661-022-10830-1","type":"journal-article","created":{"date-parts":[[2022,12,17]],"date-time":"2022-12-17T05:02:51Z","timestamp":1671253371000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Sewage from a secondary hospital in Ribeir\u00e3o Preto, southeastern Brazil: a source of multidrug-resistant Enterobacteriaceae"],"prefix":"10.1007","volume":"195","author":[{"given":"Rafael","family":"Nakamura-Silva","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo Coelho","family":"de Sousa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo Yudi","family":"Fujimoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0098-9667","authenticated-orcid":false,"given":"Andr\u00e9","family":"Pitondo-Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,12,17]]},"reference":[{"key":"10830_CR1","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1016\/j.scitotenv.2019.02.183","volume":"667","author":"A Almakki","year":"2019","unstructured":"Almakki, A., Jumas-Bilak, E., Marchandin, H., & Licznar-Fajardo, P. (2019). Antibiotic resistance in urban runoff. Science of the Total Environment, 667, 64\u201376. https:\/\/doi.org\/10.1016\/j.scitotenv.2019.02.183","journal-title":"Science of the Total Environment"},{"key":"10830_CR2","unstructured":"Brazil. (2002). Resolution of the collegiate board \u2014 RDC ANVISA no 50, 21 Feb 2002. Ministry of Health. Retrieved December 24, 2021, from https:\/\/bvsms.saude.gov.br\/bvs\/saudelegis\/anvisa\/2002\/rdc0050_21_02_2002.html"},{"key":"10830_CR3","unstructured":"Clinical and Laboratory Standards Institute (CLSI). (2020). Performance standards for antimicrobial susceptibility testing, M100. 30th ed. M02-M07."},{"issue":"11","key":"10830_CR4","doi-asserted-by":"publisher","first-page":"719","DOI":"10.1007\/s10661-021-09477-1","volume":"193","author":"LL Dias","year":"2021","unstructured":"Dias, L. L., Nakamura-Silva, R., de Oliveira Junior, G. A. T., Mego, I. O. G., Mendon\u00e7a, G. S., & Pitondo-Silva, A. (2021). Hospital liquid waste contaminated with multidrug-resistant bacteria raises a public health hazard alert in Brazil. Environmental Monitoring and Assessment, 193(11), 719. https:\/\/doi.org\/10.1007\/s10661-021-09477-1","journal-title":"Environmental Monitoring and Assessment"},{"issue":"1","key":"10830_CR5","doi-asserted-by":"publisher","first-page":"33","DOI":"10.3390\/tropicalmed5010033","volume":"5","author":"N Fouz","year":"2020","unstructured":"Fouz, N., Pangesti, K. N. A., Yasir, M., Al-Malki, A. L., Azhar, E. I., Hill-Cawthorne, G. A., & Abd El Ghany, M. (2020). The contribution of wastewater to the transmission of antimicrobial resistance in the environment: Implications of mass gathering settings. Tropical Medicine and Infectious Disease, 5(1), 33. https:\/\/doi.org\/10.3390\/tropicalmed5010033","journal-title":"Trop Med Infect Dis"},{"key":"10830_CR6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.meegid.2017.10.011","volume":"56","author":"GB Gon\u00e7alves","year":"2017","unstructured":"Gon\u00e7alves, G. B., Furlan, J. P. R., Vespero, E. C., Pelisson, M., Stehling, E. G., & Pitondo-Silva, A. (2017). Spread of multidrug-resistant high-risk Klebsiella pneumoniae clones in a tertiary hospital from southern Brazil. Infection, Genetics and Evolution, 56, 1\u20137. https:\/\/doi.org\/10.1016\/j.meegid.2017.10.011","journal-title":"Infection, Genetics and Evolution"},{"key":"10830_CR7","doi-asserted-by":"publisher","first-page":"1091","DOI":"10.2147\/IDR.S191387","volume":"13","author":"R Hajjar","year":"2020","unstructured":"Hajjar, R., Ambaraghassi, G., Sebajang, H., Schwenter, F., & Su, S. H. (2020). Raoultella ornithinolytica: Emergence and resistance. Infect Drug Resist, 13, 1091\u20131104. https:\/\/doi.org\/10.2147\/IDR.S191387","journal-title":"Infect Drug Resist"},{"key":"10830_CR8","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2020.140804","volume":"743","author":"N Hassoun-Kheir","year":"2020","unstructured":"Hassoun-Kheir, N., Stabholz, Y., Kreft, J. U., de la Cruz, R., Romalde, J. L., Nesme, J., S\u00f8rensen, S. J., Smets, B. F., Graham, D., & Paul, M. (2020). Comparison of antibiotic-resistant bacteria and antibiotic resistance genes abundance in hospital and community wastewater: A systematic review. Science of the Total Environment, 743, 140804. https:\/\/doi.org\/10.1016\/j.scitotenv.2020.140804","journal-title":"Science of the Total Environment"},{"issue":"3","key":"10830_CR9","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1038\/s12276-021-00569-z","volume":"53","author":"DW Kim","year":"2021","unstructured":"Kim, D. W., & Cha, C. J. (2021). Antibiotic resistome from the One-Health perspective: Understanding and controlling antimicrobial resistance transmission. Experimental & Molecular Medicine, 53(3), 301\u2013309. https:\/\/doi.org\/10.1038\/s12276-021-00569-z","journal-title":"Experimental & Molecular Medicine"},{"issue":"4","key":"10830_CR10","doi-asserted-by":"publisher","first-page":"565","DOI":"10.1016\/j.jmii.2016.08.016","volume":"51","author":"LH Liu","year":"2018","unstructured":"Liu, L. H., Wang, N. Y., Wu, A. Y., Lin, C. C., Lee, C. M., & Liu, C. P. (2018). Citrobacter freundii bacteremia: Risk factors of mortality and prevalence of resistance genes. Journal of Microbiology, Immunology, and Infection, 51(4), 565\u2013572. https:\/\/doi.org\/10.1016\/j.jmii.2016.08.016","journal-title":"Journal of Microbiology, Immunology, and Infection"},{"issue":"3","key":"10830_CR11","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1111\/j.1469-0691.2011.03570.x","volume":"18","author":"AP Magiorakos","year":"2012","unstructured":"Magiorakos, A. P., Srinivasan, A., Carey, R. B., Carmeli, Y., Falagas, M. E., Giske, C. G., Harbarth, S., Hindler, J. F., Kahlmeter, G., Olsson-Liljequist, B., Paterson, D. L., Rice, L. B., Stelling, J., Struelens, M. J., Vatopoulos, A., Weber, J. T., & Monnet, D. L. (2012). Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: An international expert proposal for interim standard definitions for acquired resistance. Clinical Microbiology and Infection, 18(3), 268\u2013281. https:\/\/doi.org\/10.1111\/j.1469-0691.2011.03570.x","journal-title":"Clinical Microbiology and Infection"},{"key":"10830_CR12","unstructured":"Mara, D. D. (1974). Bacteriology for sanitary engineers. Edinburgh, UK. Churchill Livingtone. 209."},{"key":"10830_CR13","doi-asserted-by":"publisher","DOI":"10.1007\/s10661-022-10454-5","author":"R Nakamura-Silva","year":"2022","unstructured":"Nakamura-Silva, R., Dias, L. L., Sousa, R. C., Fujimoto, R. Y., & Pitondo-Silva, A. (2022). Multidrug-resistant and potentially pathogenic Enterobacteriaceae found in a tertiary hospital sewage in southeastern Brazil. Environmental Monitoring and Assessment. https:\/\/doi.org\/10.1007\/s10661-022-10454-5","journal-title":"Environmental Monitoring and Assessment"},{"key":"10830_CR14","unstructured":"Prashad, Y. (2019). A critical review of the bacteria Serratia marcescens and its impact on human health. WebmedCentral Bacteriology, 10(6):WMC00557. Retrieved November 8, 2021, from http:\/\/www.webmedcentral.com\/article_view\/5573"},{"key":"10830_CR15","doi-asserted-by":"publisher","unstructured":"Rozman, U., Duh, D., Cimerman, M., & \u0160ostar-Turk, S. (2020). Hospital wastewater effluent: Hot spot for antibiotic resistant bact\u00e9ria. Journal of Water, Sanitation and Hygiene for Development, 10(2). https:\/\/doi.org\/10.2166\/washdev.2020.086","DOI":"10.2166\/washdev.2020.086"},{"key":"10830_CR16","unstructured":"SNIS (2021). National Sanitation Information System. Diagnosis of water and sewage services. Institutional website. Retrieved March 14, 2022, from http:\/\/www.snis.gov.br\/downloads\/diagnosticos\/ae\/2020\/"},{"issue":"5","key":"10830_CR17","doi-asserted-by":"publisher","first-page":"1421","DOI":"10.1128\/JCM.02680-12","volume":"51","author":"EM Tekippe","year":"2013","unstructured":"Tekippe, E. M., Shuey, S., Winkler, D. W., Butler, M. A., & Burnham, C. A. (2013). Optimizing identification of clinically relevant Gram-positive organisms by use of the Bruker Biotyper matrix-assisted laser desorption ionization-time of flight mass spectrometry system. Journal of Clinical Microbiology, 51(5), 1421\u20131427. https:\/\/doi.org\/10.1128\/JCM.02680-12","journal-title":"Journal of Clinical Microbiology"},{"issue":"9","key":"10830_CR18","doi-asserted-by":"publisher","first-page":"326","DOI":"10.3390\/microorganisms7090326","volume":"7","author":"J Turton","year":"2019","unstructured":"Turton, J., Davies, F., Turton, J., Perry, C., Payne, Z., & Pike, R. (2019). Hybrid resistance and virulence plasmids in \u201chigh-risk\u201d clones of Klebsiella pneumoniae, including those carrying blaNDM-5. Microorganisms, 7(9), 326. https:\/\/doi.org\/10.3390\/microorganisms7090326","journal-title":"Microorganisms"},{"key":"10830_CR19","unstructured":"WHO, World Health Organization. (2017). Prioritization of pathogens to guide discovery, research and development of new antibiotics for drug-resistant bacterial infections, including tuberculosis. Retrieved November 8, 2021, from https:\/\/www.who.int\/publications\/i\/item\/WHO-EMP-IAU-2017.12"},{"issue":"1","key":"10830_CR20","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.diagmicrobio.2008.04.007","volume":"62","author":"WL Yu","year":"2008","unstructured":"Yu, W. L., Ko, W. C., Cheng, K. C., Lee, C. C., Lai, C. C., & Chuang, Y. C. (2008). Comparison of prevalence of virulence factors for Klebsiella pneumoniae liver abscesses between isolates with capsular K1\/K2 and non-K1\/K2 serotypes. Diagnostic Microbiology and Infectious Disease, 62(1), 1\u20136. https:\/\/doi.org\/10.1016\/j.diagmicrobio.2008.04.007","journal-title":"Diagnostic Microbiology and Infectious Disease"},{"issue":"6","key":"10830_CR21","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1007\/s10661-020-08319-w","volume":"192","author":"GS Zagui","year":"2020","unstructured":"Zagui, G. S., de Andrade, L. N., Moreira, N. C., Silva, T. V., Machado, G. P., da Costa Darini, A. L., &, & Segura-Mu\u00f1oz, S. I. (2020). Gram-negative bacteria carrying \u03b2-lactamase encoding genes in hospital and urban wastewater in Brazil. Environmental Monitoring and Assessment, 192(6), 376. https:\/\/doi.org\/10.1007\/s10661-020-08319-w","journal-title":"Environmental Monitoring and Assessment"},{"key":"10830_CR22","doi-asserted-by":"publisher","DOI":"10.1590\/1519-6984.234471","volume":"82","author":"GS Zagui","year":"2022","unstructured":"Zagui, G. S., Tonani, K. A. A., Fregonesi, B. M., Machado, G. P., Silva, T. V., Andrade, L. N., Andrade, D., & Segura-Mu\u00f1oz, S. I. (2022). Tertiary hospital sewage as reservoir of bacteria expressing MDR phenotype in Brazil. Brazilian Journal of Biology, 82, e234471. https:\/\/doi.org\/10.1590\/1519-6984.234471","journal-title":"Brazilian Journal of Biology"}],"container-title":["Environmental Monitoring and Assessment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10661-022-10830-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10661-022-10830-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10661-022-10830-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,27]],"date-time":"2023-01-27T09:53:23Z","timestamp":1674813203000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10661-022-10830-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,17]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,1]]}},"alternative-id":["10830"],"URL":"https:\/\/doi.org\/10.1007\/s10661-022-10830-1","relation":{},"ISSN":["0167-6369","1573-2959"],"issn-type":[{"value":"0167-6369","type":"print"},{"value":"1573-2959","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,17]]},"assertion":[{"value":"7 June 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 December 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 December 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"204"}}