{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T17:19:11Z","timestamp":1771003151317,"version":"3.50.1"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2007,7,17]],"date-time":"2007-07-17T00:00:00Z","timestamp":1184630400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Familial Cancer"],"published-print":{"date-parts":[[2008,3]]},"DOI":"10.1007\/s10689-007-9144-x","type":"journal-article","created":{"date-parts":[[2007,7,17]],"date-time":"2007-07-17T02:35:15Z","timestamp":1184639715000},"page":"53-58","source":"Crossref","is-referenced-by-count":36,"title":["Hereditary gynecologic cancers: differential diagnosis, surveillance, management and surgical prophylaxis"],"prefix":"10.1007","volume":"7","author":[{"given":"Karen H.","family":"Lu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2007,7,17]]},"reference":[{"issue":"2","key":"9144_CR1","doi-asserted-by":"crossref","first-page":"106","DOI":"10.3322\/canjclin.56.2.106","volume":"56","author":"A Jemal","year":"2006","unstructured":"Jemal A et al (2006) Cancer statistics, 2006. CA Cancer J Clin 56(2):106\u2013130","journal-title":"CA Cancer J Clin"},{"issue":"2","key":"9144_CR2","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1002\/(SICI)1097-0215(19990412)81:2<214::AID-IJC8>3.0.CO;2-L","volume":"81","author":"M Aarnio","year":"1999","unstructured":"Aarnio M et al (1999) Cancer risk in mutation carriers of DNA-mismatch-repair genes. Int J Cancer 81(2):214\u2013218","journal-title":"Int J Cancer"},{"issue":"1","key":"9144_CR3","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1093\/hmg\/6.1.105","volume":"6","author":"MG Dunlop","year":"1997","unstructured":"Dunlop MG et al (1997) Cancer risk associated with germline DNA mismatch repair gene mutations. Hum Mol Genet 6(1):105\u2013110","journal-title":"Hum Mol Genet"},{"key":"9144_CR4","first-page":"421","volume":"92","author":"K Lu","year":"2004","unstructured":"Lu K et al (2004) Gynecological malignancy as a \u201cSentinel Cancer\u201d for women with HNPCC. Gynecol Oncol 92:421","journal-title":"Gynecol Oncol"},{"issue":"4","key":"9144_CR5","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1093\/jnci\/djh034","volume":"96","author":"A Umar","year":"2004","unstructured":"Umar A et al (2004) Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability. J Natl Cancer Inst 96(4):261\u2013268","journal-title":"J Natl Cancer Inst"},{"issue":"23","key":"9144_CR6","doi-asserted-by":"crossref","first-page":"4364","DOI":"10.1200\/JCO.2003.04.094","volume":"21","author":"MJ Berends","year":"2003","unstructured":"Berends MJ et al (2003) Toward new strategies to select young endometrial cancer patients for mismatch repair gene mutation analysis. J Clin Oncol 21(23):4364\u20134370","journal-title":"J Clin Oncol"},{"key":"9144_CR7","doi-asserted-by":"crossref","unstructured":"Lu K, S.J., Rodabaugh K, Sun C, Daniels MS, White KG, Soliman PT, Luthra R, Broaddus RR. Defining criteria for Lynch Syndrome\/HNPCC in women under 50 with endometrial cancer: Final results of a prospective, multi-center study. in 1st Conference of InSIGHT, the International Society for Gastrointestinal Hereditary Tumors. 2005. Newcastle, UK: Familial Cancer","DOI":"10.1200\/jco.2005.23.16_suppl.9547"},{"issue":"5","key":"9144_CR8","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1093\/hmg\/8.5.823","volume":"8","author":"AL Millar","year":"1999","unstructured":"Millar AL et al (1999) Mismatch repair gene defects contribute to the genetic basis of double primary cancers of the colorectum and endometrium. Hum Mol Genet 8(5):823\u2013829","journal-title":"Hum Mol Genet"},{"issue":"2","key":"9144_CR9","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.ygyno.2004.05.006","volume":"94","author":"PT Soliman","year":"2004","unstructured":"Soliman PT et al (2004) Synchronous primary cancers of the endometrium and ovary: a single institution review of 84 cases. Gynecol Oncol 94(2):456\u2013462","journal-title":"Gynecol Oncol"},{"issue":"12","key":"9144_CR10","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1001\/jama.1997.03540360065034","volume":"277","author":"W Burke","year":"1997","unstructured":"Burke W et al (1997) Recommendations for follow-up care of individuals with an inherited predisposition to cancer. II. BRCA1 and BRCA2. Cancer Genetics Studies Consortium. JAMA 277(12):997\u20131003","journal-title":"JAMA"},{"key":"9144_CR11","unstructured":"NCCN Clinical Practice Guidelines in Oncology: Genetic\/Familial High-Risk Assessment: Breast and Ovarian. Vol. Version 1.2006. 2006, Rockledge, PA: National Comprehensive Cancer Network"},{"key":"9144_CR12","unstructured":"Lu KH, Soliman PT, Boyd-Rogers SG, Daniels MS, Broaddus RR, Lynch PM, Peterson SK (2005) A prospective pilot study of combined colon and endometrial cancer screening in women with HNPCC. Familial Cancer 4:104\u2013105"},{"issue":"6","key":"9144_CR13","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1001\/jama.1987.03390060086029","volume":"257","author":"Combination oral contraceptive use and the risk of endometrial cancer","year":"1987","unstructured":"Combination oral contraceptive use and the risk of endometrial cancer (1987) The Cancer and Steroid Hormone Study of the Centers for Disease Control and the National Institute of Child Health and Human Development. JAMA 257(6):796\u2013800","journal-title":"JAMA"},{"issue":"3","key":"9144_CR14","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1056\/NEJMoa052627","volume":"354","author":"KM Schmeler","year":"2006","unstructured":"Schmeler KM et al (2006) Prophylactic surgery to reduce the risk of gynecologic cancers in the Lynch syndrome. N Engl J Med 354(3):261\u2013269","journal-title":"N Engl J Med"},{"issue":"5 Pt 2","key":"9144_CR15","first-page":"1152","volume":"102","author":"L Chung","year":"2003","unstructured":"Chung L et al (2003) Unexpected endometrial cancer at prophylactic hysterectomy in a woman with hereditary nonpolyposis colon cancer. Obstet Gynecol 102(5 Pt 2):1152\u20131155","journal-title":"Obstet Gynecol"},{"issue":"7","key":"9144_CR16","doi-asserted-by":"crossref","first-page":"2417","DOI":"10.1200\/JCO.1998.16.7.2417","volume":"16","author":"TS Frank","year":"1998","unstructured":"Frank TS et al (1998) Sequence analysis of BRCA1 and BRCA2: correlation of mutations with family history and ovarian cancer risk. J Clin Oncol 16(7):2417\u20132425","journal-title":"J Clin Oncol"},{"issue":"1","key":"9144_CR17","first-page":"34","volume":"93","author":"KH Lu","year":"1999","unstructured":"Lu KH et al (1999) A population-based study of BRCA1 and BRCA2 mutations in Jewish women with epithelial ovarian cancer. Obstet Gynecol 93(1):34\u201337","journal-title":"Obstet Gynecol"},{"issue":"4","key":"9144_CR18","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1086\/302853","volume":"66","author":"R Moslehi","year":"2000","unstructured":"Moslehi R et al (2000) BRCA1 and BRCA2 mutation analysis of 208 Ashkenazi Jewish women with ovarian cancer. Am J Hum Genet 66(4):1259\u20131272","journal-title":"Am J Hum Genet"},{"issue":"1","key":"9144_CR19","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.ygyno.2004.09.039","volume":"96","author":"KA Metcalfe","year":"2005","unstructured":"Metcalfe KA et al (2005) The risk of ovarian cancer after breast cancer in BRCA1 and BRCA2 carriers. Gynecol Oncol 96(1):222\u2013226","journal-title":"Gynecol Oncol"},{"issue":"22","key":"9144_CR20","doi-asserted-by":"crossref","first-page":"4222","DOI":"10.1200\/JCO.2003.04.131","volume":"21","author":"DA Levine","year":"2003","unstructured":"Levine DA et al (2003) Fallopian tube and primary peritoneal carcinomas associated with BRCA mutations. J Clin Oncol 21(22):4222\u20134227","journal-title":"J Clin Oncol"},{"key":"9144_CR21","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1111\/j.1525-1438.2006.00480.x","volume":"16 Suppl 1","author":"KN Gaarenstroom","year":"2006","unstructured":"Gaarenstroom KN et al (2006) Efficacy of screening women at high risk of hereditary ovarian cancer: results of an 11-year cohort study. Int J Gynecol Cancer 16 Suppl 1:54\u201359","journal-title":"Int J Gynecol Cancer"},{"issue":"2","key":"9144_CR22","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/j.ygyno.2005.01.024","volume":"97","author":"PA Meeuwissen","year":"2005","unstructured":"Meeuwissen PA et al (2005) Outcome of surveillance and prophylactic salpingo-oophorectomy in asymptomatic women at high risk for ovarian cancer. Gynecol Oncol 97(2):476\u2013482","journal-title":"Gynecol Oncol"},{"issue":"24","key":"9144_CR23","doi-asserted-by":"crossref","first-page":"5588","DOI":"10.1200\/JCO.2005.05.097","volume":"23","author":"D Stirling","year":"2005","unstructured":"Stirling D et al (2005) Screening for familial ovarian cancer: failure of current protocols to detect ovarian cancer at an early stage according to the international Federation of gynecology and obstetrics system. J Clin Oncol 23(24):5588\u20135596","journal-title":"J Clin Oncol"},{"issue":"11","key":"9144_CR24","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1056\/NEJM198703123161102","volume":"316","author":"The reduction in risk of ovarian cancer associated with oral-contraceptive use","year":"1987","unstructured":"The reduction in risk of ovarian cancer associated with oral-contraceptive use (1987) The Cancer and Steroid Hormone Study of the Centers for Disease Control and the National Institute of Child Health and Human Development. N Engl J Med 316(11):650\u2013655","journal-title":"N Engl J Med"},{"issue":"23","key":"9144_CR25","doi-asserted-by":"crossref","first-page":"1706","DOI":"10.1056\/NEJM200112063452312","volume":"345","author":"SA Narod","year":"2001","unstructured":"Narod SA, Sun P, Risch HA (2001) Ovarian cancer, oral contraceptives, and BRCA mutations. N Engl J Med 345(23):1706\u20131707","journal-title":"N Engl J Med"},{"issue":"11","key":"9144_CR26","doi-asserted-by":"crossref","first-page":"1911","DOI":"10.1038\/sj.bjc.6602239","volume":"91","author":"AS Whittemore","year":"2004","unstructured":"Whittemore AS et al (2004) Oral contraceptive use and ovarian cancer risk among carriers of BRCA1 or BRCA2 mutations. Br J Cancer 91(11):1911\u20131915","journal-title":"Br J Cancer"},{"issue":"4","key":"9144_CR27","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1056\/NEJM200107263450401","volume":"345","author":"B Modan","year":"2001","unstructured":"Modan B et al (2001) Parity, oral contraceptives, and the risk of ovarian cancer among carriers and noncarriers of a BRCA1 or BRCA2 mutation. N Engl J Med 345(4):235\u2013240","journal-title":"N Engl J Med"},{"issue":"23","key":"9144_CR28","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1093\/jnci\/94.23.1773","volume":"94","author":"SA Narod","year":"2002","unstructured":"Narod SA et al (2002) Oral contraceptives and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers. J Natl Cancer Inst 94(23):1773\u20131779","journal-title":"J Natl Cancer Inst"},{"issue":"21","key":"9144_CR29","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1056\/NEJMoa012158","volume":"346","author":"TR Rebbeck","year":"2002","unstructured":"Rebbeck TR et al (2002) Prophylactic oophorectomy in carriers of BRCA1 or BRCA2 mutations. N Engl J Med 346(21):1616\u20131622","journal-title":"N Engl J Med"},{"issue":"21","key":"9144_CR30","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1056\/NEJMoa020119","volume":"346","author":"ND Kauff","year":"2002","unstructured":"Kauff ND et al (2002) Risk-reducing salpingo-oophorectomy in women with a BRCA1 or BRCA2 mutation. N Engl J Med 346(21):1609\u201315","journal-title":"N Engl J Med"},{"issue":"3","key":"9144_CR31","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1097\/01.AOG.0000228959.30577.13","volume":"108","author":"KM Schmeler","year":"2006","unstructured":"Schmeler KM et al (2006) Prophylactic Bilateral Salpingo-Oophorectomy Compared With Surveillance in Women With BRCA Mutations. Obstet Gynecol 108(3):515\u2013520","journal-title":"Obstet Gynecol"},{"issue":"31","key":"9144_CR32","doi-asserted-by":"crossref","first-page":"7804","DOI":"10.1200\/JCO.2004.00.8151","volume":"23","author":"TR Rebbeck","year":"2005","unstructured":"Rebbeck TR et al (2005) Effect of short-term hormone replacement therapy on breast cancer risk reduction after bilateral prophylactic oophorectomy in BRCA1 and BRCA2 mutation carriers: the PROSE Study Group. J Clin Oncol 23(31):7804\u20137810","journal-title":"J Clin Oncol"},{"issue":"14","key":"9144_CR33","doi-asserted-by":"crossref","first-page":"2728","DOI":"10.1200\/JCO.2000.18.14.2728","volume":"18","author":"KH Lu","year":"2000","unstructured":"Lu KH et al (2000) Occult ovarian tumors in women with BRCA1 or BRCA2 mutations undergoing prophylactic oophorectomy. J Clin Oncol 18(14):2728\u20132732","journal-title":"J Clin Oncol"},{"issue":"10","key":"9144_CR34","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1097\/00000478-200110000-00009","volume":"25","author":"TJ Colgan","year":"2001","unstructured":"Colgan TJ et al (2001) Occult carcinoma in prophylactic oophorectomy specimens: prevalence and association with BRCA germline mutation status. Am J Surg Pathol 25(10):1283\u20131289","journal-title":"Am J Surg Pathol"},{"issue":"1","key":"9144_CR35","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1200\/JCO.2005.04.109","volume":"23","author":"CB Powell","year":"2005","unstructured":"Powell CB et al (2005) Risk-reducing salpingo-oophorectomy in BRCA mutation carriers: role of serial sectioning in the detection of occult malignancy. J Clin Oncol 23(1):127\u2013132","journal-title":"J Clin Oncol"}],"container-title":["Familial Cancer"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10689-007-9144-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10689-007-9144-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10689-007-9144-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,30]],"date-time":"2019-05-30T21:45:56Z","timestamp":1559252756000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10689-007-9144-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,7,17]]},"references-count":35,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,3]]}},"alternative-id":["9144"],"URL":"https:\/\/doi.org\/10.1007\/s10689-007-9144-x","relation":{},"ISSN":["1389-9600","1573-7292"],"issn-type":[{"value":"1389-9600","type":"print"},{"value":"1573-7292","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,7,17]]}}}