{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T08:32:45Z","timestamp":1774686765943,"version":"3.50.1"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2016,4,12]],"date-time":"2016-04-12T00:00:00Z","timestamp":1460419200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Familial Cancer"],"published-print":{"date-parts":[[2016,10]]},"DOI":"10.1007\/s10689-016-9906-4","type":"journal-article","created":{"date-parts":[[2016,4,14]],"date-time":"2016-04-14T09:22:36Z","timestamp":1460625756000},"page":"645-649","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Ventricular fibrillation resulting from electrolyte imbalance reveals vipoma in MEN1 syndrome"],"prefix":"10.1007","volume":"15","author":[{"given":"Tiziana","family":"Cavalli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Giudici","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raffaella","family":"Santi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriella","family":"Nesi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Luisa","family":"Brandi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Tonelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,4,12]]},"reference":[{"key":"9906_CR1","doi-asserted-by":"publisher","first-page":"33","DOI":"10.4158\/EP10376.RA","volume":"17","author":"F Tonelli","year":"2011","unstructured":"Tonelli F, Giudici F, Fratini G, Brandi ML (2011) Pancreatic endocrine tumors in multiple endocrine neoplasia type 1 syndrome: review of literature. Endocr Pract 17:33\u201340. doi: 10.4158\/EP10376.RA","journal-title":"Endocr Pract"},{"key":"9906_CR2","doi-asserted-by":"publisher","first-page":"504","DOI":"10.3390\/cancers4020504","volume":"4","author":"F Tonelli","year":"2012","unstructured":"Tonelli F, Giudici F, Giusti F, Brandi ML (2012) Gastroenteropancreatic neuroendocrine tumors in multiple endocrine neoplasia type 1. Cancers (Basel) 4:504\u2013522. doi: 10.3390\/cancers4020504","journal-title":"Cancers (Basel)"},{"issue":"2","key":"9906_CR3","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1007\/s00268-009-0290-1","volume":"34","author":"P Goudet","year":"2010","unstructured":"Goudet P, Murat A, Binquet C, Cardot-Bauters C, Costa A, Ruszniewski P, Niccoli P, M\u00e9n\u00e9gaux F, Chabrier G, Borson-Chazot F, Tabarin A, Bouchard P, Delemer B, Beckers A, Bonithon-Kopp C (2010) Risk factors and causes of death in MEN1 disease. A GTE (Groupe d\u2019Etude des Tumeurs Endocrines) cohort study among 758 patients. World J Surg 34(2):249\u2013255. doi: 10.1007\/s00268-009-0290-1","journal-title":"World J Surg"},{"key":"9906_CR4","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1677\/ERC-07-0221","volume":"15","author":"TR Halfdanarson","year":"2008","unstructured":"Halfdanarson TR, Rubin J, Farnell MB, Grant CS, Petersen GM (2008) Pancreatic endocrine neoplasms: epidemiology and prognosis of pancreatic endocrine tumors. Endocr Relat Cancer 15:409\u2013427. doi: 10.1677\/ERC-07-0221","journal-title":"Endocr Relat Cancer"},{"key":"9906_CR5","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/0002-9343(58)90075-5","volume":"25","author":"JV Verner","year":"1958","unstructured":"Verner JV, Morrison AB (1958) Islet cell tumor and a syndrome of refractory watery diarrhoea and hypokalemia. Am J Med 25:374\u2013380","journal-title":"Am J Med"},{"key":"9906_CR6","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1056\/NEJM198312153092403","volume":"309","author":"MG Kane","year":"1983","unstructured":"Kane MG, O\u2019Dorisio TM, Krejs GJ (1983) Production of secretory diarrhoea by intravenous infusion of vasoactive intestinal polypeptide. N Engl J Med 309:1482\u20131485","journal-title":"N Engl J Med"},{"issue":"5764","key":"9906_CR7","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1038\/285417a0","volume":"285","author":"K Tatemoto","year":"1980","unstructured":"Tatemoto K, Mutt V (1980) Isolation of two novel candidate hormones using a chemical method for finding naturally occurring polypeptides. Nature 285(5764):417\u2013418","journal-title":"Nature"},{"issue":"6","key":"9906_CR8","doi-asserted-by":"crossref","first-page":"535","DOI":"10.2337\/diab.24.6.535","volume":"24","author":"I Blum","year":"1975","unstructured":"Blum I, Doron M, Laron Z, Atsmon A, Tiqva P (1975) Prevention of hypoglycemic attacks by propranolol in a patient suffering from insulinoma. Diabetes 24(6):535\u2013537","journal-title":"Diabetes"},{"issue":"2","key":"9906_CR9","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/0002-9610(70)90028-0","volume":"119","author":"AR Kraft","year":"1970","unstructured":"Kraft AR, Tompkins RK, Zollinger RM (1970) Recognition and management of the diarrheal syndrome caused by nonbeta islet cell tumors of the pancreas. Am J Surg 119(2):163\u2013170","journal-title":"Am J Surg"},{"issue":"1","key":"9906_CR10","first-page":"G46","volume":"244","author":"CA Sninsky","year":"1983","unstructured":"Sninsky CA, Wolfe MM, Martin JL et al (1983) Myoelectric effects of vasoactive intestinal peptide on rabbit small intestine. Am J Physiol 244(1):G46\u2013G51","journal-title":"Am J Physiol"},{"issue":"6","key":"9906_CR11","doi-asserted-by":"crossref","first-page":"724","DOI":"10.6004\/jnccn.2012.0075","volume":"10","author":"MH Kulke","year":"2012","unstructured":"Kulke MH, Benson AB III, Bergsland E et al (2012) Neuroendocrine tumors. J Natl Compr Cancer Netw 10(6):724\u2013764","journal-title":"J Natl Compr Cancer Netw"},{"issue":"4","key":"9906_CR12","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1097\/MPA.0b013e31828e34a4","volume":"42","author":"PL Kunz","year":"2013","unstructured":"Kunz PL, Reidy-Lagunes D, Anthony LB et al (2013) Consensus guidelines for the management and treatment of neuroendocrine tumors. Pancreas 42(4):557\u2013577","journal-title":"Pancreas"},{"issue":"2","key":"9906_CR13","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1097\/01.sla.0000197715.96762.68","volume":"243","author":"F Triponez","year":"2006","unstructured":"Triponez F, Dosseh D, Goudet P, Cougard P, Bauters C, Murat A, Cadiot G, Niccoli-Sire P, Chayvialle JA, Calender A, Proye CA (2006) Epidemiology data on 108 MEN 1 patients from the GTE with isolated nonfunctioning tumors of the pancreas. Ann Surg 243(2):265\u2013272","journal-title":"Ann Surg"},{"issue":"4","key":"9906_CR14","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1111\/j.1365-2265.2011.04227.x","volume":"76","author":"A Sakurai","year":"2012","unstructured":"Sakurai A, Suzuki S, Kosugi S, Okamoto T, Uchino S, Miya A, Imai T, Kaji H, Komoto I, Miura D, Yamada M, Uruno T, Horiuchi K, Miyauchi A, Imamura M, MEN Consortium of Japan, Fukushima T, Hanazaki K, Hirakawa S, Igarashi T, Iwatani T, Kammori M, Katabami T, Katai M, Kikumori T, Kiribayashi K, Koizumi S, Midorikawa S, Miyabe R, Munekage T, Ozawa A, Shimizu K, Sugitani I, Takeyama H, Yamazaki M (2012) Multiple endocrine neoplasia type 1 in Japan: establishment and analysis of a multicentre database. Clin Endocrinol (Oxf) 76(4):533\u2013539. doi: 10.1111\/j.1365-2265.2011.04227.x","journal-title":"Clin Endocrinol (Oxf)"},{"key":"9906_CR15","first-page":"988","volume-title":"Sleisenger and Fordtran\u2019s gastrointestinal and liver diseases","author":"RT Jensen","year":"2002","unstructured":"Jensen RT, Norton JA (2002) Pancreatic endocrine tumors. In: Felman M, Friedman LS, Sleisenger MH (eds) Sleisenger and Fordtran\u2019s gastrointestinal and liver diseases. Saunders, Philadelphia, pp 988\u20131016"},{"issue":"1","key":"9906_CR16","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1055\/s-0033-1344958","volume":"46","author":"T Hasegawa","year":"2014","unstructured":"Hasegawa T, Yamao K, Hijioka S, Bhatia V, Mizuno N, Hara K, Imaoka H, Niwa Y, Tajika M, Kondo S, Tanaka T, Shimizu Y, Kinoshita T, Kohsaki T, Nishimori I, Iwasaki S, Saibara T, Hosoda W, Yatabe Y (2014) Evaluation of Ki-67 index in EUS\u2013FNA specimens for the assessment of malignancy risk in pancreatic neuroendocrine tumors. Endoscopy 46(1):32\u201338. doi: 10.1055\/s-0033-1344958 (Epub 11 Nov 2013)","journal-title":"Endoscopy"},{"key":"9906_CR17","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1097\/00006676-200401000-00015","volume":"28","author":"SY Peng","year":"2004","unstructured":"Peng SY, Li JT, Liu YB, Fang HQ, Wu YL, Peng CH et al (2004) Diagnosis and treatment of VIPoma in China: (case report and 31 cases review) diagnosis and treatment of VIPoma. Pancreas 28:93\u201397","journal-title":"Pancreas"},{"key":"9906_CR18","first-page":"419","volume":"20","author":"D Lambertini","year":"2003","unstructured":"Lambertini D, Bottini E, Talassi E, Tarchini R, Gaetti L, Bellomi A (2003) Acute renal failure caused by VIP-secreting tumor. G Ital Nefrol 20:419\u2013422","journal-title":"G Ital Nefrol"},{"issue":"1","key":"9906_CR19","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1007\/BF00430771","volume":"367","author":"JC Rambaud","year":"1975","unstructured":"Rambaud JC, Galian A, Scotto J et al (1975) Pancreatic cholera (W.D.H.A. syndrome). Histochemical and ultrastructural studies. Virchows Arch A 367(1):35\u201345","journal-title":"Virchows Arch A"},{"issue":"10","key":"9906_CR20","first-page":"606","volume":"45","author":"J K\u00e1brt","year":"1999","unstructured":"K\u00e1brt J, Dvor\u00e1k M, Skrha J, Sindelka G (1999) Diagnosis and treatment of pancreatic islet cell tumors producing vasoactive intestinal polypeptide (VIPoma). Vnitr Lek 45(10):606\u2013609","journal-title":"Vnitr Lek"},{"key":"9906_CR21","doi-asserted-by":"publisher","first-page":"S215","DOI":"10.4103\/2230-8210.119576","volume":"17","author":"RR Maheshwari","year":"2013","unstructured":"Maheshwari RR, Desai M, Rao VP, Palanki RR, Namburi RP, Reddy KT, Reddy AP (2013) Ischemic stroke as a presenting feature of VIPoma due to MEN1 syndrome. Indian J Endocrinol Metab 17:S215\u2013S218. doi: 10.4103\/2230-8210.119576","journal-title":"Indian J Endocrinol Metab"},{"key":"9906_CR22","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1148\/radiology.214.2.r00fe32483","volume":"214","author":"RF Thoeni","year":"2000","unstructured":"Thoeni RF, Mueller-Lisse UG, Chan R, Do NK, Shyn PB (2000) Detection of small, functional islet cell tumors in the pancreas: selection of MR imaging sequences for optimal sensitivity. Radiology 214:483\u2013490","journal-title":"Radiology"},{"key":"9906_CR23","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1148\/rg.262055056","volume":"26","author":"KM Horton","year":"2006","unstructured":"Horton KM, Hruban RH, Yeo C, Fishman EK (2006) Multi-detector row CT of pancreatic islet cell tumors. Radiographics 26:453\u2013464","journal-title":"Radiographics"},{"key":"9906_CR24","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1002\/(SICI)1522-2586(200002)11:2<141::AID-JMRI10>3.0.CO;2-U","volume":"11","author":"RC Semelka","year":"2000","unstructured":"Semelka RC, Custodio CM, Cem Balci N, Woosley JT (2000) Neuroendocrine tumors of the pancreas: spectrum of appearances on MRI. J Magn Reson Imaging 11:141\u2013148","journal-title":"J Magn Reson Imaging"},{"key":"9906_CR25","doi-asserted-by":"publisher","first-page":"1445","DOI":"10.1148\/rg.306105523","volume":"30","author":"RB Lewis","year":"2010","unstructured":"Lewis RB, Lattin GE, Paal E (2010) Pancreatic endocrine tumors: radiologic-clinicopathologic correlation. Radiographics 30:1445\u20131464. doi: 10.1148\/rg.306105523","journal-title":"Radiographics"},{"key":"9906_CR26","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.yasu.2012.04.002","volume":"46","author":"TA Ellison","year":"2012","unstructured":"Ellison TA, Edil BH (2012) The current management of pancreatic neuroendocrine tumors. Adv Surg 46:283\u2013296","journal-title":"Adv Surg"},{"key":"9906_CR27","first-page":"528","volume":"10","author":"A Anaye","year":"2009","unstructured":"Anaye A, Mathieu A, Closset J, Bali MA, Metens T, Matos C (2009) Successful preoperative localization of a small pancreatic insulinoma by diffusion-weighted MRI. JOP 10:528\u2013531","journal-title":"JOP"},{"key":"9906_CR28","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1097\/00003072-200009000-00001","volume":"25","author":"JW Thomason","year":"2000","unstructured":"Thomason JW, Martin RS, Fincher ME (2000) Somatostatin receptor scintigraphy: the definitive technique for characterizing vasoactive intestinal peptide-secreting tumors. Clin Nucl Med 25:661\u2013664","journal-title":"Clin Nucl Med"},{"issue":"5","key":"9906_CR29","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1007\/s00268-006-0360-y","volume":"30","author":"MA Kouvaraki","year":"2006","unstructured":"Kouvaraki MA, Shapiro SE, Cote GJ, Lee JE, Yao JC, Waguespack SG, Gagel RF, Evans DB, Perrier ND (2006) Management of pancreatic endocrine tumors in multiple endocrine neoplasia type 1. World J Surg 30(5):643\u2013653","journal-title":"World J Surg"}],"container-title":["Familial Cancer"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10689-016-9906-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10689-016-9906-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10689-016-9906-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,30]],"date-time":"2019-05-30T21:46:19Z","timestamp":1559252779000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10689-016-9906-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4,12]]},"references-count":29,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,10]]}},"alternative-id":["9906"],"URL":"https:\/\/doi.org\/10.1007\/s10689-016-9906-4","relation":{},"ISSN":["1389-9600","1573-7292"],"issn-type":[{"value":"1389-9600","type":"print"},{"value":"1573-7292","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,4,12]]}}}