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When surveillance efforts for those at familial and hereditary risk of pancreatic cancer emerged in the late 1990s, it was uncertain if early detection was achievable.<\/jats:p><jats:p>In this introduction to the special issue, we offer an overview of the history of surveillance for pancreatic cancer, including the first reports of familial pancreatic cancer in the medical literature, the initial results of surveillance in the United States and the initiation of surveillance programs for hereditary pancreatic cancer in the Netherlands.<\/jats:p><jats:p>This special issue features a collection of 18 articles written by prominent experts in the field, focusing specifically on refining surveillance methodologies with the primary objective of improving care of high-risk individuals. Several reviews in this collection highlight improved survival rates associated with pancreas surveillance, underlying the potential of early detection and improved management in the continuing fight against pancreatic cancer.<\/jats:p>","DOI":"10.1007\/s10689-024-00404-0","type":"journal-article","created":{"date-parts":[[2024,6,6]],"date-time":"2024-06-06T16:01:27Z","timestamp":1717689687000},"page":"209-215","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Twenty-five years of surveillance for familial and hereditary pancreatic ductal adenocarcinoma: Historical perspectives and introduction to the special issue"],"prefix":"10.1007","volume":"23","author":[{"given":"Hans FA","family":"Vasen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcia Irene","family":"Canto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Goggins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,6,6]]},"reference":[{"issue":"22","key":"404_CR1","doi-asserted-by":"publisher","first-page":"1569","DOI":"10.1056\/NEJM199705293362206","volume":"336","author":"JC Bailar","year":"1997","unstructured":"Bailar JC 3rd, Gornik HL (1997) Cancer undefeated. 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Marcia I Canto: Royalties UpToDate (familial pancreatic cancer), Michael Goggins: no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}