{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T10:43:53Z","timestamp":1762253033364,"version":"3.37.3"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2019,7,2]],"date-time":"2019-07-02T00:00:00Z","timestamp":1562025600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,7,2]],"date-time":"2019-07-02T00:00:00Z","timestamp":1562025600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"Science and Technology Commission of the Shanghai Municipality","award":["No.13ZR1419600"],"award-info":[{"award-number":["No.13ZR1419600"]}]},{"name":"Hydrobiological Project of Shanghai Leading Academic Discipline","award":["NO. S30701"],"award-info":[{"award-number":["NO. S30701"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Fish Physiol Biochem"],"published-print":{"date-parts":[[2019,8]]},"DOI":"10.1007\/s10695-019-00653-2","type":"journal-article","created":{"date-parts":[[2019,7,2]],"date-time":"2019-07-02T14:06:31Z","timestamp":1562076391000},"page":"1431-1443","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Cloning, molecular characterization, and tissue differential expression of connective tissue growth factor (ctgf) of grass carp"],"prefix":"10.1007","volume":"45","author":[{"given":"Wen-Qian","family":"Pan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun-Peng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhi-Han","family":"Tu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tian","family":"Gan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Wei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiang-Jun","family":"Leng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3562-9389","authenticated-orcid":false,"given":"Xiao-Qin","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,7,2]]},"reference":[{"key":"653_CR1","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1038\/ncb826","volume":"4","author":"JG Abreu","year":"2002","unstructured":"Abreu JG, Ketpura NI, Reversade B, De Robertis EM (2002) Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta. Nat Cell Biol 4:599\u2013604","journal-title":"Nat Cell Biol"},{"key":"653_CR2","doi-asserted-by":"publisher","first-page":"2958","DOI":"10.1128\/MCB.19.4.2958","volume":"19","author":"AM Babic","year":"1999","unstructured":"Babic AM, Chen CC, Lau LF (1999) Fisp12\/mouse connective tissue growth factor mediates endothelial cell adhesion and migration through integrin v3, promotes endothelial cell survival, and induces angiogenesis in vivo. Mol Cell Biol 19:2958\u20132966","journal-title":"Mol Cell Biol"},{"key":"653_CR3","doi-asserted-by":"publisher","first-page":"828","DOI":"10.1095\/biolreprod59.4.828","volume":"59","author":"DK Ball","year":"1998","unstructured":"Ball DK, Surveyor GA, Diehl JR, Steffen CL, Uzumcu M, Mirando MA, Brigstock DR (1998) Characterization of 16- to 20-kilodalton (kDa) connective tissue growth factors (CTGFs) and demonstration of proteolytic activity for 38-kDa CTGF in pig uterine luminal flushings. Biol Reprod 59:828\u2013835","journal-title":"Biol Reprod"},{"key":"653_CR4","doi-asserted-by":"publisher","first-page":"1290","DOI":"10.1002\/bjs.5431","volume":"93","author":"D Beddy","year":"2006","unstructured":"Beddy D, Mulsow J, Watson RW, Fitzpatrick JM, O\u2019Connell PR (2006) Expression and regulation of connective tissue growth factor by transforming growth factor beta and tumour necrosis factor alpha in fibroblasts isolated from strictures in patients with Crohn\u2019s disease. Br J Surg 93:1290\u20131296","journal-title":"Br J Surg"},{"key":"653_CR5","doi-asserted-by":"publisher","first-page":"1139","DOI":"10.1093\/ndt\/16.6.1139","volume":"16","author":"IE Blom","year":"2001","unstructured":"Blom IE, van Dijk AJ, Wieten L, Duran K, Ito Y, Kleij L, deNichilo M, Rabelink TJ, Weening JJ, Aten J, Goldschmeding R (2001) In vitro evidence for differential involvement of CTGF, TGFbeta, and PDGF-BB in mesangial response to injury. Nephrol Dial Transplant 16:1139\u20131148","journal-title":"Nephrol Dial Transplant"},{"key":"653_CR6","doi-asserted-by":"publisher","first-page":"770","DOI":"10.1164\/rccm.200210-1254OC","volume":"168","author":"P Bonniaud","year":"2003","unstructured":"Bonniaud P, Margetts PJ, Kolb M, Haberberger T, Kelly M, Robertson J, Gauldie J (2003) Adenoviral gene transfer of connective tissue growth factor in the lung induces transient fibrosis. Am J Respir Crit Care Med 168:770\u2013778","journal-title":"Am J Respir Crit Care Med"},{"key":"653_CR7","first-page":"189","volume":"20","author":"DR Brigstock","year":"1999","unstructured":"Brigstock DR (1999) The connective tissue growth factor\/cysteine-rich 61\/nephroblastoma overexpressed (CCN) family. Endocr Rev 20:189\u2013206","journal-title":"Endocr Rev"},{"key":"653_CR8","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1136\/mp.56.2.127","volume":"56","author":"DR Brigstock","year":"2003","unstructured":"Brigstock DR, Goldschmeding R, Katsube KI, Lam SC, Lau LF, Lyons K, Naus C, Perbal B, Riser B, Takigawa M, Yeger H (2003) Proposal for a unified CCN nomenclature. Mol Pathol 56:127\u2013128","journal-title":"Mol Pathol"},{"key":"653_CR9","doi-asserted-by":"publisher","first-page":"20275","DOI":"10.1074\/jbc.272.32.20275","volume":"272","author":"DR Brigstock","year":"1997","unstructured":"Brigstock DR, Steffen CL, Kim GY, Vegunta RK, Diehl JR, Harding PA (1997) Purification and characterization of novel heparin-binding growth factors in uterine secretory fluids: identification as heparin-regulated Mr 10,000 forms of connective tissue growth factor. J Biol Chem 272:20275\u201320282","journal-title":"J Biol Chem"},{"key":"653_CR10","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1089\/dna.1991.10.293","volume":"10","author":"A Brunner","year":"1991","unstructured":"Brunner A, Chinn J, Neubauer M, Purchio AF (1991) Identification of a gene family regulated by transforming growth factor-\u03b2. DNA Cell Biol 10:293\u2013300","journal-title":"DNA Cell Biol"},{"key":"653_CR11","doi-asserted-by":"publisher","first-page":"5635","DOI":"10.1091\/mbc.e04-06-0490","volume":"15","author":"Y Chen","year":"2004","unstructured":"Chen Y, Abraham DJ, Shi WX, Pearson JD, Black CM, Lyons KM, Leask A (2004) CCN2 (connective tissue growth factor) promotes fibroblast adhesion to fibronectin. Mol Biol Cell 15:5635\u20135646","journal-title":"Mol Biol Cell"},{"key":"653_CR12","doi-asserted-by":"publisher","first-page":"909","DOI":"10.1016\/S1357-2725(98)00046-6","volume":"30","author":"J Dammeier","year":"1998","unstructured":"Dammeier J, Brauchle M, Falk W, Grotendorst GR, Werner S (1998) Connective tissue growth factor: a novel regulator of mucosal repair and fibrosis in inflammatory bowel disease? Int J Biochem Cell Biol 30:909\u2013922","journal-title":"Int J Biochem Cell Biol"},{"key":"653_CR13","doi-asserted-by":"publisher","first-page":"8454","DOI":"10.1128\/MCB.00821-07","volume":"27","author":"RA Dean","year":"2007","unstructured":"Dean RA, Butler GS, Yamina HK, Delb\u00e9 J, Brigstock DR, Courty J, Overal CM (2007) Identification of candidate angiogenic inhibitors processed by matrix metalloproteinase 2 (MMP-2) in cell-based proteomic screens: disruption of vascular endothelial growth factor (VEGF)\/heparin affin regulatory peptide (pleiotrophin) and VEGF\/connective tissue growth factor angiogenic inhibitory complexes by MMP-2 proteolysis. Mol Cell Biol 27:8454\u20138465","journal-title":"Mol Cell Biol"},{"key":"653_CR14","doi-asserted-by":"crossref","unstructured":"Fernando CA, Conrad PA, Bartels CF, Marques T, To M, Balow SA, Nakamura Y, Warman ML (2010) Temporal and spatial expression of CCN genes in zebrafish. J Developmental Dynamics 239(6):1755\u20131767","DOI":"10.1002\/dvdy.22279"},{"key":"653_CR15","doi-asserted-by":"publisher","first-page":"8848","DOI":"10.1074\/jbc.M313204200","volume":"279","author":"R Gao","year":"2004","unstructured":"Gao R, Brigstock DR (2004) Connective tissue growth factor (CCN2) induces adhesion of rat activated hepatic stellate cells by binding of its C-terminal domain to integrin alpha (v) beta (3) and heparan sulfate proteoglycan. J Biol Chem 279:8848\u20138855","journal-title":"J Biol Chem"},{"key":"653_CR16","first-page":"469","volume":"7","author":"GR Grotendorst","year":"1996","unstructured":"Grotendorst GR, Okochi H, Hayashi N (1996) A novel transforming growth factor \u03b2 response element controls the expression of the connective tissue growth factor gene. Cell Growth Differ 7:469\u2013480","journal-title":"Cell Growth Differ"},{"key":"653_CR17","doi-asserted-by":"publisher","first-page":"36288","DOI":"10.1074\/jbc.M201674200","volume":"277","author":"G Hashimoto","year":"2002","unstructured":"Hashimoto G, Inoki I, Fujii Y, Aoki T, Ikeda E, Okada Y (2002) Matrix metalloproteinases cleave connective tissue growth factor and reactivate angiogenic activity of vascular endothelial growth factor 165. J Biol Chem 277:36288\u201336295","journal-title":"J Biol Chem"},{"key":"653_CR18","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1111\/1523-1747.ep12318465","volume":"105","author":"A Igarashi","year":"1995","unstructured":"Igarashi A, Nashiro K, Kikuchi K, Sato S, Ihn H, Grotendorst GR, Takehara K (1995) Significant correlation between connective tissue growth factor gene expression and skin sclerosis in tissue sections from patients with systemic sclerosis. J Invest Dermatol 105:280\u2013284","journal-title":"J Invest Dermatol"},{"key":"653_CR19","doi-asserted-by":"publisher","first-page":"637","DOI":"10.1091\/mbc.4.6.637","volume":"4","author":"A Igarashi","year":"1993","unstructured":"Igarashi A, Okochi H, Bradham DM, Grotendorst GR (1993) Regulation of connective tissue growth factor gene expression in human skin fibroblasts and during wound repair. Mol Biol Cell 4:637\u2013645","journal-title":"Mol Biol Cell"},{"key":"653_CR20","doi-asserted-by":"publisher","first-page":"681","DOI":"10.1097\/00002281-200211000-00009","volume":"14","author":"H Ihn","year":"2002","unstructured":"Ihn H (2002) Pathogenesis of fibrosis: role of TGF-beta and CTGF. Curr Opin Rheumatol 14:681\u2013685","journal-title":"Curr Opin Rheumatol"},{"key":"653_CR21","doi-asserted-by":"publisher","first-page":"2779","DOI":"10.1242\/dev.00505","volume":"130","author":"S Ivkovic","year":"2003","unstructured":"Ivkovic S, Yoon BS, Popoff SN, Safadi FF, Libuda de Stephenson RC, Daluiski A, Lyons KM (2003) Connective tissue growth factor coordinates chondrogenesis and angiogenesis during skeletal development. Development 130:2779\u20132791","journal-title":"Development"},{"key":"653_CR22","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1016\/j.pnsc.2007.06.010","volume":"18","author":"XH Kong","year":"2008","unstructured":"Kong XH, Wang ZX, Gan XN, Li JB, He SP (2008) Molecular evolution of connective tissue growth factor of Cyprinidae (Teleostei: Cypriniformes). Prog Nat Sci 18:155\u2013160","journal-title":"Prog Nat Sci"},{"key":"653_CR23","first-page":"L365","volume":"275","author":"JA Lasky","year":"1998","unstructured":"Lasky JA, Ortiz LA, Tonthat B, Hoyle GW, Corti M, Athas G, Lungarella G, Brody A, Friedman M (1998) Connective tissue growth factor mRNA expression is upregulated in bleomycin-induced lung fibrosis. Am J Phys 275:L365\u2013L371","journal-title":"Am J Phys"},{"key":"653_CR24","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1006\/excr.1999.4456","volume":"248","author":"LF Lau","year":"1999","unstructured":"Lau LF, Lam SC (1999) The CCN family of angiogenic regulators: the integrin connection. Exp Cell Res 248:44\u201357","journal-title":"Exp Cell Res"},{"issue":"Pt23","key":"653_CR25","doi-asserted-by":"publisher","first-page":"4803","DOI":"10.1242\/jcs.03270","volume":"119","author":"A Leask","year":"2006","unstructured":"Leask A, Abraham DJ (2006) All in the CCN family: essential matricellular signaling modulators emerge from the bunker. J Cell Sci 119(Pt23):4803\u20134810","journal-title":"J Cell Sci"},{"key":"653_CR26","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1002\/jgm.894","volume":"8","author":"G Li","year":"2006","unstructured":"Li G, Xie Q, Shi Y, Li D, Zhang M, Jiang S, Zhou H, Lu H, Jin Y (2006) Inhibition of connective tissue growth factor by siRNA prevents liver fibrosis in rats. J Gene Med 8:889\u2013900","journal-title":"J Gene Med"},{"key":"653_CR27","doi-asserted-by":"crossref","unstructured":"Mercurio S, Latinkic B, Itasaki N, Krumlauf R, Smith JC (2004) Connective-tissue growth factor modulates WNT signalling and interacts with the WNT receptor complex. Development 131(9):2137\u20132147","DOI":"10.1242\/dev.01045"},{"key":"653_CR28","doi-asserted-by":"crossref","unstructured":"Meyer A, Peer YV (2005) From 2R to 3R: evidence for a fish-specific genome duplication (FSGD). Bioessays 27(9):937\u2013945","DOI":"10.1002\/bies.20293"},{"key":"653_CR29","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1016\/S0955-0674(99)00039-3","volume":"11","author":"A Meyer","year":"1999","unstructured":"Meyer A, Schartl M (1999) Gene and genome duplications in vertebrates: the one-to-four (-to-eight in fish) rule and the evolution of novel gene functions. Curr Op Cell Biol 11:699\u2013704","journal-title":"Curr Op Cell Biol"},{"key":"653_CR30","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1006\/mgme.2000.3059","volume":"71","author":"EE Moussad","year":"2000","unstructured":"Moussad EE, Brigstock DR (2000) Connective tissue growth factor: what\u2019s in a name? Mol Genet Metab 71:276\u2013292","journal-title":"Mol Genet Metab"},{"key":"653_CR31","doi-asserted-by":"publisher","first-page":"1094","DOI":"10.1016\/j.yexcr.2007.12.010","volume":"314","author":"Y Mori","year":"2008","unstructured":"Mori Y, Hinchcliff M, Wu M, Warner BM, M Lyons K, Varga J (2008) Connective tissue growth factor\/CCN2-null mouse embryonic fibroblasts retain intact transforming growth factor-beta responsiveness. Exp Cell Res 314:1094\u20131104","journal-title":"Exp Cell Res"},{"key":"653_CR32","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1002\/(SICI)1097-4652(199910)181:1<153::AID-JCP16>3.0.CO;2-K","volume":"181","author":"T Mori","year":"1999","unstructured":"Mori T, Kawara S, Shinozaki M, Hayashi N, Kakinuma T, Igarashi A, Takigawa M, Nakanishi T, Takehara K (1999) Role and interaction of connective tissue growth factor with transforming growth factorbeta in persistent fibrosis: a mouse fibrosis model. J Cell Physiol 181:153\u2013159","journal-title":"J Cell Physiol"},{"key":"653_CR33","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1210\/endo.141.1.7267","volume":"141","author":"T Nakanishi","year":"2000","unstructured":"Nakanishi T, Nishida T, Shimo T, Kobayashi K, Kubo T, Tamatani T, Tezuka K, Takigawa M (2000) Effects of CTGF\/Hcs24, a product of a hypertrophic chondrocyte-specific gene, on the proliferation and differentiation of chondrocytes in culture. Endocrinology 141:264\u2013273","journal-title":"Endocrinology"},{"key":"653_CR34","doi-asserted-by":"publisher","first-page":"678","DOI":"10.1006\/bbrc.2001.4379","volume":"281","author":"T Nakanishi","year":"2001","unstructured":"Nakanishi T, Yamaai T, Asano M, Nawachi K, Suzuki M, Sugimoto T, Takigawa M (2001) Overexpression of connective tissue growth factor\/hypertrophic chondrocyte-specific gene product 24 decreases bone density in adult mice and induces dwarfism. Biochem Biophys Res Commun 281:678\u2013681","journal-title":"Biochem Biophys Res Commun"},{"key":"653_CR35","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1002\/1097-4652(200008)184:2<197::AID-JCP7>3.0.CO;2-R","volume":"184","author":"T Nishida","year":"2000","unstructured":"Nishida T, Nakanishi T, Asano M, Shimo T, Takigawa M (2000) Effects of CTGF\/Hcs24, a hypertrophic chondrocyte-specific gene product, on the proliferation and differentiation of osteoblastic cells in vitro. J Cell Physiol 184:197\u2013206","journal-title":"J Cell Physiol"},{"key":"653_CR36","volume-title":"Hackensack","author":"B Perbal","year":"2005","unstructured":"Perbal B, Takigawa M (2005) CCN proteins: a new family of cell growth and differentiation regulators. In: Hackensack. Imperial College Press, London"},{"key":"653_CR37","doi-asserted-by":"publisher","first-page":"1045","DOI":"10.1359\/jbmr.060416","volume":"21","author":"T Shimo","year":"2006","unstructured":"Shimo T, Kubota S, Yoshioka N, Ibaragi S, Isowa S, Eguchi T, Sasaki A, Takigawa M (2006) Pathogenic role of connective tissue growth factor (CTGF\/CCN2) in osteolytic metastasis of breast cancer. J Bone Miner Res 21:1045\u20131059","journal-title":"J Bone Miner Res"},{"key":"653_CR38","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1093\/oxfordjournals.jbchem.a022071","volume":"124","author":"T Shimo","year":"1998","unstructured":"Shimo T, Nakanishi T, Kimura Y, Nishida T, Ishizeki K, Matsumura T, Takigawa M (1998) Inhibition of endogenous expression of connective tissue growth factor by its antisense oligonucleotide and antisense RNA suppresses proliferation and migration of vascular endothelial cells. J Biochem (Tokyo) 124:130\u2013140","journal-title":"J Biochem (Tokyo)"},{"key":"653_CR39","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1080\/08977190512331340566","volume":"23","author":"F S\u00f6nke","year":"2005","unstructured":"S\u00f6nke F, Heike H, Stephanie C (2005) Gene expression of connective tissue growth factor in adult mouse. J Growth Factors 23:43\u201353","journal-title":"J Growth Factors"},{"key":"653_CR40","first-page":"179","volume":"22","author":"BY Su","year":"2002","unstructured":"Su BY, Cai WQ (2002) Progress in the study of CCN family. J First Mil Med Univ 22:179\u2013183","journal-title":"J First Mil Med Univ"},{"key":"653_CR41","unstructured":"Sun T (2012) Coloning, expression and SNP excavating of CCN family in common carp, PhD thesis, Shanghai Ocean University"},{"key":"653_CR42","first-page":"755","volume":"30","author":"K Takehara","year":"2003","unstructured":"Takehara K (2003) Hypothesis: pathogenesis of systemic sclerosis. J Rheumatol 30:755\u2013759","journal-title":"J Rheumatol"},{"key":"653_CR43","doi-asserted-by":"publisher","first-page":"748","DOI":"10.1006\/bbrc.1998.9543","volume":"251","author":"T Tamatani","year":"1998","unstructured":"Tamatani T, Kobayashi H, Tezuka K, Sakamoto S, Suzuki K, Nakanishi T, Takigawa M, Miyano T (1998) Establishment of the enzyme-linked immunosorbent assay for connective tissue growth factor (CTGF) and its detection in the sera of biliary atresia. Biochem Biophys Res Commun 251:748\u2013752","journal-title":"Biochem Biophys Res Commun"},{"key":"653_CR44","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1136\/mp.55.1.40","volume":"55","author":"P Vorwerk","year":"2002","unstructured":"Vorwerk P, Wex H, Hohmann B, Mohnike K, Schmidt U, Mittler U (2002) Expression of components of the IGF signalling system in child-hood acute lymphoblastic leukaemia. Mol Pathol 55:40\u201345","journal-title":"Mol Pathol"},{"key":"653_CR45","unstructured":"Wang Y (2014) Molecular cloning of CTGF genes and the study on the construction and transgenic efficiency of PB transposon and PB-Tgf2 transposition system in Megalobrama amblycephala, PhD thesis, Shanghai Ocean University"},{"key":"653_CR46","first-page":"8917","volume":"61","author":"D Xie","year":"2001","unstructured":"Xie D, Nakachi K, Wang H, Elashoff R, Koeffler HP (2001) Elevated levels of ccn1, ccn2 and ccn4 in primary breast cancers associated with more advanced features. Cancer Res 61:8917\u20138923","journal-title":"Cancer Res"},{"key":"653_CR47","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1016\/0378-1119(95)00891-8","volume":"171","author":"Z Ying","year":"1996","unstructured":"Ying Z, Ling ML (1996) Isolation and characterization of xnov, a Xenopus laevis ortholog of the chicken nov gene. Gene 171:243\u2013248","journal-title":"Gene"},{"key":"653_CR48","doi-asserted-by":"publisher","first-page":"3414","DOI":"10.3748\/wjg.v10.i23.3414","volume":"10","author":"ZJ Zeng","year":"2004","unstructured":"Zeng ZJ, Yang LY, Ding X, Wang W (2004) Expressions of cysteine-rich 61, connective tissue growth factor and Nov genes in hepatocellular carcinoma and their clinical significance. World J Gastroenterol 10:3414\u20133418","journal-title":"World J Gastroenterol"},{"key":"653_CR49","first-page":"220","volume":"26","author":"Q Zhang","year":"2006","unstructured":"Zhang Q, Lin Y (2006) The relationship between connective tissue growth factor and vascular remodeling. Int J Respiration 26:220\u2013222","journal-title":"Int J Respiration"}],"container-title":["Fish Physiology and Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10695-019-00653-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10695-019-00653-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10695-019-00653-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:04:53Z","timestamp":1593561893000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10695-019-00653-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7,2]]},"references-count":49,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,8]]}},"alternative-id":["653"],"URL":"https:\/\/doi.org\/10.1007\/s10695-019-00653-2","relation":{},"ISSN":["0920-1742","1573-5168"],"issn-type":[{"type":"print","value":"0920-1742"},{"type":"electronic","value":"1573-5168"}],"subject":[],"published":{"date-parts":[[2019,7,2]]},"assertion":[{"value":"24 May 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 May 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 July 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}