{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T22:12:56Z","timestamp":1787004776713,"version":"build-2736575974"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"1-2","license":[{"start":{"date-parts":[[2006,2,1]],"date-time":"2006-02-01T00:00:00Z","timestamp":1138752000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Glycoconj J"],"published-print":{"date-parts":[[2006,2]]},"DOI":"10.1007\/s10719-006-5436-x","type":"journal-article","created":{"date-parts":[[2006,3,30]],"date-time":"2006-03-30T13:22:35Z","timestamp":1143724955000},"page":"39-49","source":"Crossref","is-referenced-by-count":27,"title":["Differential usage of carbohydrate co-receptors influences cellular tropism of Theiler's murine encephalomyelitis virus infection of the central nervous system"],"prefix":"10.1007","volume":"23","author":[{"given":"Howard L.","family":"Lipton","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. S. Manoj","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shannon","family":"Hertzler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Honey V.","family":"Reddi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"5436_CR1","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.1128\/JVI.61.5.1507-1516.1987","volume":"61","author":"D.C. Pevear","year":"1987","unstructured":"Pevear, D.C., Calenoff, M., Rozhon, E., Lipton, H.L.: Analysis of the complete nucleotide sequence of the picornavirus Theiler's murine encephalomyelitis virus indicates that it is closely related to cardioviruses. J. Virol. 61, 1507\u20131516 (1987)","journal-title":"J. Virol."},{"key":"5436_CR2","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1126\/science.80.2066.122-a","volume":"80","author":"M. Theiler","year":"1934","unstructured":"Theiler, M.: Spontaneous encephalomyelitis of mice - a new virus disease. Science. 80, 122 (1934)","journal-title":"Science"},{"key":"5436_CR3","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/S0168-1702(01)00256-8","volume":"76","author":"H.L. Lipton","year":"2001","unstructured":"Lipton, H.L., Kim, B.S., Yahikozawa, H., Nadler, C.F.: Serological evidence that Mus musculus is the natural host of Theiler's murine encephalomyelitis virus. Virus Res.. 76, 79\u201386 (2001)","journal-title":"Virus Res.."},{"key":"5436_CR4","doi-asserted-by":"crossref","first-page":"434","DOI":"10.3181\/00379727-41-10701","volume":"43","author":"P.K. Olitsky","year":"1939","unstructured":"Olitsky, P.K.: Viral effect produced by intestinal contents of normal mice and those having spontaneous encephalomyelitis. Proc. Soc. Exp. Biol. Med. 43, 434\u2013437 (1939)","journal-title":"Proc. Soc. Exp. Biol. Med."},{"key":"5436_CR5","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1097\/00005792-194120040-00002","volume":"20","author":"M. Theiler","year":"1941","unstructured":"Theiler, M.: Studies on poliomyelitis. Medicine. 20, 443\u2013462 (1941)","journal-title":"Medicine."},{"key":"5436_CR6","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1128\/IAI.11.5.1147-1155.1975","volume":"11","author":"H.L. Lipton","year":"1975","unstructured":"Lipton, H.L.: Theiler's virus infection in mice: An unusual biphasic disease process leading to demyelination. Infect. Immun. 11, 1147\u20131155 (1975)","journal-title":"Infect. Immun."},{"key":"5436_CR7","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/0022-510X(76)90167-2","volume":"29","author":"J.R. Lehrich","year":"1976","unstructured":"Lehrich, J.R., Arnason, B.G.W., Hochberg, F.H.: Demyelinating myelopathy in mice induced by the DA virus. J. Neurol. Sci. 29, 149\u2013160 (1976)","journal-title":"J. Neurol. Sci."},{"key":"5436_CR8","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/S0966-842X(02)02383-1","volume":"10","author":"M.G. Rossmann","year":"2002","unstructured":"Rossmann, M.G., He, Y., Kuhn, R.J.: Picornavirus-receptor interactions. Trends Microbiol. 10, 324\u2013331 (2002)","journal-title":"Trends Microbiol."},{"key":"5436_CR9","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1038\/317145a0","volume":"317","author":"M.G. Rossmann","year":"1985","unstructured":"Rossmann, M.G., Arnold, E., Erickson, J.W., Frankenberger, E.A., Griffith, J.P., Hecht, H.-J., Johnson, J.E., Kamer, G., Luo, M., Mosser, A.G., Rueckert, R.R., Sherry, B., Vriend, G.: Structure of a human common cold virus and functional relationship to other picornaviruses. Nature. 317, 145\u2013153 (1985)","journal-title":"Nature."},{"key":"5436_CR10","doi-asserted-by":"crossref","first-page":"1358","DOI":"10.1126\/science.2994218","volume":"229","author":"J.M. Hogle","year":"1985","unstructured":"Hogle, J.M., Chow, M., Filman, D.J.: Three-dimensional structure of poliovirus at 2.9 \u00c5 resolution. Science. 229, 1358\u20131365 (1985)","journal-title":"Science."},{"key":"5436_CR11","doi-asserted-by":"crossref","first-page":"5244","DOI":"10.1128\/JVI.65.10.5244-5249.1991","volume":"65","author":"D.R. Kilpatrick","year":"1991","unstructured":"Kilpatrick, D.R., Lipton, H.L.: Predominant binding of Theiler's viruses to a 34-kilodalton receptor protein on susceptible cell lines. J. Virol. 65, 5244\u20135249 (1991)","journal-title":"J. Virol."},{"key":"5436_CR12","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/0042-6822(91)90683-3","volume":"182","author":"C. Fotiadis","year":"1991","unstructured":"Fotiadis, C., Kilpatrick, D.R., Lipton, H.L.: Comparison of the binding characteristics to BHK-21 cells of viruses representing the two Theiler's virus neurovirulence groups. Virology 182, 365\u2013370 (1991)","journal-title":"Virology"},{"key":"5436_CR13","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1006\/viro.2002.1735","volume":"304","author":"A.H. Shah","year":"2002","unstructured":"Shah, A.H., Lipton, H.L.: Low-neurovirulence Theiler's viruses use sialic acid moieties on Nlinked oligosaccharide structures for attachment. Virology 304, 443\u2013450 (2002)","journal-title":"Virology"},{"key":"5436_CR14","doi-asserted-by":"crossref","first-page":"8400","DOI":"10.1128\/JVI.76.16.8400-8407.2002","volume":"76","author":"H.V. Reddi","year":"2002","unstructured":"Reddi, H.V., Lipton, H.L.: Heparan sulfate mediates infection of high-neurovirulence Theiler's viruses. J. Virol. 76, 8400\u20138407 (2002)","journal-title":"J. Virol."},{"key":"5436_CR15","doi-asserted-by":"crossref","first-page":"2485","DOI":"10.1099\/0022-1317-81-10-2485","volume":"81","author":"S. Hertzler","year":"2000","unstructured":"Hertzler, S., Trottier, M., Lipton, H.L.: Selection and characterization of a BHK-21 cell line resistant to infection by Theiler's murine encephalomyelitis virus due to a block in virus attachment and entry. J. Gen. Virol. 81, 2485\u20132490 (2000)","journal-title":"J. Gen. Virol."},{"key":"5436_CR16","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1099\/vir.0.18746-0","volume":"84","author":"H.V. Reddi","year":"2003","unstructured":"Reddi, H.V., Lipton, H.L.: Galactose is needed only for expression of co-receptors used by Theiler's murine encephalomyelitis virus as the virus does not directly bind galactose or use the UDP-galactose transporter as a receptor. J. Gen. Virol. 84, 845\u2013849 (2003)","journal-title":"J. Gen. Virol."},{"key":"5436_CR17","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1016\/0300-9084(88)90290-8","volume":"70","author":"W. McDowell","year":"1988","unstructured":"McDowell, W., Schwarz, R.T.: Dissecting glycoprotein biosynthesis by the use of specific inhibitors. Biochimie. 70, 1535\u20131549 (1988)","journal-title":"Biochimie."},{"key":"5436_CR18","doi-asserted-by":"crossref","first-page":"14155","DOI":"10.1016\/S0021-9258(19)45358-1","volume":"257","author":"B. Saunier","year":"1982","unstructured":"Saunier, B., Kilker, R.D., Tkacz, J.S., Quaroni, A.Q., Hersocovics, A.: Inhibition of N-linked complex oligosaccharide formation by 1-deoxynojirimycin, an inhibitor of processing glucosidases. J Biol Chem. 257, 14155\u201314161 (1982)","journal-title":"J Biol Chem."},{"key":"5436_CR19","doi-asserted-by":"crossref","first-page":"8609","DOI":"10.1016\/S0021-9258(19)75264-8","volume":"252","author":"J. Umemoto","year":"1977","unstructured":"Umemoto, J., Bhavanandan, V.P., Davidson, E.A.: Purification and properties of an endo-alpha- N-acetyl-D-galactosaminidase from Diplococcus pneumoniae. J Biol Chem. 252, 8609\u20138614 (1977)","journal-title":"J Biol Chem."},{"key":"5436_CR20","doi-asserted-by":"crossref","first-page":"9701","DOI":"10.1128\/JVI.71.12.9701-9712.1997","volume":"71","author":"L. Zhou","year":"1997","unstructured":"Zhou, L., Lin, X., Green, T.J., Lipton, H.L., Luo, M.: Role of sialyloligosaccharide binding in Theiler's virus persistence. J. Virol. 71, 9701\u20139712 (1997)","journal-title":"J. Virol."},{"key":"5436_CR21","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1128\/JVI.74.3.1477-1485.2000","volume":"74","author":"L. Zhou","year":"2000","unstructured":"Zhou, L., Luo, Y., Wu, Y., Tsao, J., Luo, M.: Sialylation of the host receptor may modulate entry of demyelinating persistent Theiler's virus. J. Virol. 74, 1477\u20131485 (2000)","journal-title":"J. Virol."},{"key":"5436_CR22","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1006\/viro.1996.0309","volume":"220","author":"M. Luo","year":"1996","unstructured":"Luo, M., Toth, K.S., Zhou, L., Pritchard, A., Lipton, H.L.: The structure of a highly virulent Theiler's murine encephalomyelitis virus (GDVII) and implications for determinants of viral persistence. Virology 220, 246\u2013250 (1996)","journal-title":"Virology"},{"key":"5436_CR23","doi-asserted-by":"crossref","first-page":"2709","DOI":"10.1128\/JVI.77.4.2709-2716.2003","volume":"77","author":"A.S. Kumar","year":"2003","unstructured":"Kumar, A.S., Kallio, P., Luo, M., Lipton, H.L.: Amino acid substitutions of low neurovirulence VP2 residues contacting sialic acid dramatically reduce viral binding and spread. J. Virol. 77, 2709\u20132716 (2003)","journal-title":"J. Virol."},{"key":"5436_CR24","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.1128\/JVI.72.2.1662-1665.1998","volume":"72","author":"C. Adami","year":"1998","unstructured":"Adami, C., Pritchard, A.E., Knauf, T., Luo, M., Lipton, H.L.: Mapping a determinant for central nervous system persistence in the capsid of Theiler's murine encephalomyelitis virus (TMEV) with recombinant viruses. J. Virol. 72, 1662\u20131665 (1998)","journal-title":"J. Virol."},{"key":"5436_CR25","doi-asserted-by":"crossref","first-page":"8860","DOI":"10.1128\/JVI.78.16.8860-8867.2004","volume":"78","author":"A.S.M. Kumar","year":"2004","unstructured":"Kumar, A.S.M., Reddi, H.V., Kung, A.Y., Dal, Canto MC, Lipton, H.L.: Virus persistence in an animal model requires virion attachment to sialic acid coreceptors. J. Virol. 78, 8860\u20138867 (2004)","journal-title":"J. Virol."},{"key":"5436_CR26","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/0042-6822(90)90198-Z","volume":"175","author":"S. Kim","year":"1990","unstructured":"Kim, S., Boege, U., Krishnaswamy, S., Minor, I., Smith, T.J., Luo, M., Scraba, D.G., Rossmann, M.G.: Conformational variability of a picornavirus capsid: pH-dependent structural changes of Mengo virus related to its host receptor attachment site and disassembly. Virology 175, 176\u2013190 (1990)","journal-title":"Virology"},{"key":"5436_CR27","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/0042-6822(90)90249-Q","volume":"176","author":"R.J. Clatch","year":"1990","unstructured":"Clatch, R.J., Miller, S.D., Metzner, R., Dal Canto, M.C., Lipton, H.L.: Monocytes\/macrophages isolated from the mouse central nervous system contain infectious Theiler's murine encephalomyelitis virus (TMEV). Virology 176, 244\u2013254 (1990)","journal-title":"Virology"},{"key":"5436_CR28","doi-asserted-by":"crossref","first-page":"2525","DOI":"10.1128\/JVI.69.4.2525-2533.1995","volume":"69","author":"H.L. Lipton","year":"1995","unstructured":"Lipton, H.L., Twaddle, G., Jelachich, M.L.: The predominant virus antigen burden is present in macrophages in Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease. J. Virol. 69, 2525\u20132533 (1995)","journal-title":"J. Virol."},{"key":"5436_CR29","doi-asserted-by":"crossref","first-page":"3336","DOI":"10.1128\/JVI.71.4.3336-3340.1997","volume":"71","author":"C. Pena-Rossi","year":"1997","unstructured":"Pena-Rossi, C., Delcroix, M., Huitinga, I., McAllister, A., van Rooijen, N., Claassen, E., Brahic, M.: Role of macrophages during Theiler's virus infection. J. Virol. 71, 3336\u20133340 (1997)","journal-title":"J. Virol."},{"key":"5436_CR30","doi-asserted-by":"crossref","first-page":"5930","DOI":"10.1128\/JVI.75.13.5930-5938.2001","volume":"75","author":"M.L. Jelachich","year":"2001","unstructured":"Jelachich, M.L., Lipton, H.L.: Theiler's murine encephalomyelitis virus induces apoptosis in gamma interferon activated M1 differentiated myelomonocytic cells through a mechanism 22 involving tumor necrosis factor alpha (TNF-\u03b1) and TNF-\u03b1-related apoptosis-inducing ligand. J. Virol. 75, 5930\u20135938 (2001)","journal-title":"J. Virol."},{"key":"5436_CR31","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1006\/viro.2001.0981","volume":"286","author":"S. Hertzler","year":"2001","unstructured":"Hertzler, S., Kallio, P., Lipton, H.L.: UDP-galactose transporter is required for Theiler's virus entry into mammalian cells. Virology 286, 336\u2013344 (2001)","journal-title":"Virology"},{"key":"5436_CR32","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1146\/annurev.biochem.68.1.729","volume":"68","author":"M. Bernfield","year":"1999","unstructured":"Bernfield, M., Gotte, M., Park, P.W., Reizes, O., Fitzgerald, M.L., Lincecum, J., Zako, M.: Functions of cell surface heparan sulfate proteoglycans. Ann. Rev. Biochem. 68, 729\u2013777 (1999)","journal-title":"Ann. Rev. Biochem."},{"key":"5436_CR33","doi-asserted-by":"crossref","first-page":"4918","DOI":"10.1128\/JVI.75.10.4918-4921.2001","volume":"75","author":"I.G. Goodfellow","year":"2001","unstructured":"Goodfellow, I.G., Sioofy, A.B., Powell, R.M., Evans, D.J.: Echoviruses bind heparan sulfate at the cell surface. J. Virol. 75, 4918\u20134921 (2001)","journal-title":"J. Virol."},{"key":"5436_CR34","doi-asserted-by":"crossref","first-page":"5282","DOI":"10.1128\/JVI.70.8.5282-5287.1996","volume":"70","author":"T. Jackson","year":"1996","unstructured":"Jackson, T., Ellard, F.M., Ghazaleh, R.A., Brookes, S.M., Blakemore, W.E., Corteyn, A.H., Stuart, D.I., Newman, J.W.I., King, A.M.Q.: Efficient infection of cells in culture by type-O foot-and-mouth disease virus requires binding to cell surface heparan sulfate. J. Virol. 70, 5282\u20135287 (1996)","journal-title":"J. Virol."},{"key":"5436_CR35","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1093\/emboj\/18.3.543","volume":"18","author":"E.E. Fry","year":"1999","unstructured":"Fry, E.E., Lea, S.M., Jackson, T., Newman, J.W., Ellard, F.M., Blakemore, W.E., Abu Ghazaleh, R., Samuel, A., King, A.M.Q, Stuart, D.I.: The structure and function of a foot-and-mouth diseasevirus oligosaccharide receptor complex. EMBO J. 18, 543\u2013554 (1999)","journal-title":"EMBO J."},{"key":"5436_CR36","doi-asserted-by":"crossref","first-page":"10071","DOI":"10.1128\/JVI.77.18.10071-10077.2003","volume":"77","author":"A.E. Zautner","year":"2003","unstructured":"Zautner, A.E., Korner, U., Henke, A., Dadorff, C., Schmidtke, M.: Heparan sulfate mediates swine vesicular disease virus attachment to the host cell. J. Virol. 77, 10071\u201310077 (2003)","journal-title":"J. Virol."},{"key":"5436_CR37","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1099\/vir.0.19603-0","volume":"85","author":"E. Escribano-Romero","year":"2004","unstructured":"Escribano-Romero, E., Jimenez-Clavero, M.A., Gomes, P., Garcia-Ranea, J.A., Ley, V.: Heparan sulfate mediates swine vesicular disease virus attachment to the host cell. J. Gen. Virol. 85, 653\u2013663 (2004)","journal-title":"J. Gen. Virol."},{"key":"5436_CR38","doi-asserted-by":"crossref","first-page":"29923","DOI":"10.1074\/jbc.R000008200","volume":"275","author":"P.W. Park","year":"2000","unstructured":"Park, P.W., Reizes, O., Bernfield, M.: Cell surface heparan sulfate proteoglycans: Selective regulators of ligand-receptor encounters. J. Biol. Chem. 275, 29923\u201329926 (2000)","journal-title":"J. Biol. Chem."},{"key":"5436_CR39","unstructured":"Huet, G., Kim, I., de Bolos, C., Lo-Guidice, J.M., Moreau, O., Hemon, B., Richet, C., Delannoy, P., Real, F.X., Degand, P.: Characterization of mucins and proteoglycans synthesized by a mucin-secreting HT-29 cell subpopulation. J Cell Sci. 108, 1275\u20131285 (1996) 23"},{"key":"5436_CR40","doi-asserted-by":"crossref","first-page":"2267","DOI":"10.1073\/pnas.89.6.2267","volume":"89","author":"K. Lidholt","year":"1992","unstructured":"Lidholt, K., Weinke, J.L., Kiser, C.S., Lugemwa, F.N., Bame, K.J., Cheifetz, S., Massague, J., Lindahl, U., Esko, J.D.: A single mutation affects both N-acetylglucosaminyltransferase and glucuronosyltransferase activities in a Chinese hamster ovary cell mutant defective in heparan sulfate biosynthesis. Proc. Natl. Acad. Sci. USA. 89, 2267\u20132271 (1992)","journal-title":"Proc. Natl. Acad. Sci. USA."},{"key":"5436_CR41","doi-asserted-by":"crossref","first-page":"8909","DOI":"10.1128\/JVI.78.16.8909-8916.2004","volume":"78","author":"H.V. Reddi","year":"2004","unstructured":"Reddi, H.V., Kumar, A.S.M., Kung, A.Y., Lipton, H.L. Heparan sulfate-dependent infection attenuates high-neurovirulence GDVII virus-induced. J. Virol. 78, 8909\u20138916 (2004)","journal-title":"J. Virol."},{"key":"5436_CR42","doi-asserted-by":"crossref","first-page":"13017","DOI":"10.1074\/jbc.274.19.13017","volume":"19","author":"X. Bai","year":"1999","unstructured":"Bai, X., Wei, G., Sinha, A., Esko, J.D.: Chinese hamster ovary cell mutants defective in glycosaminoglycan assembly and glucuronosyltransferase I. J. Biol. Chem. 19, 13017\u201313024 (1999)","journal-title":"J. Biol. Chem."},{"key":"5436_CR43","first-page":"691","volume":"119","author":"D.X. Guido","year":"1992","unstructured":"Guido, D.X., Bai, X.-M., Van Der Schueren, B., Cassiman, J.-J., Van Den Berghe H. Developmental changes in heparan sulfate expression: In situ detection with mAbs. J. Cell. Biol. 119, 691\u2013975 (1992)","journal-title":"J. Cell. Biol."},{"key":"5436_CR44","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0945-053X(00)00137-2","volume":"20","author":"U. Hartman","year":"2001","unstructured":"Hartman, U., Maurer, P.: Proteoglycans in the nervous system\u2014the quest for functional roles in vivo. Matrix Biology. 20, 23\u201335 (2001)","journal-title":"Matrix Biology."}],"container-title":["Glycoconjugate Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10719-006-5436-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10719-006-5436-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10719-006-5436-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,25]],"date-time":"2021-07-25T07:47:45Z","timestamp":1627199265000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10719-006-5436-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,2]]},"references-count":44,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2006,2]]}},"alternative-id":["5436"],"URL":"https:\/\/doi.org\/10.1007\/s10719-006-5436-x","relation":{},"ISSN":["0282-0080","1573-4986"],"issn-type":[{"value":"0282-0080","type":"print"},{"value":"1573-4986","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,2]]}}}