{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T22:43:53Z","timestamp":1778625833821,"version":"3.51.4"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2010,10,23]],"date-time":"2010-10-23T00:00:00Z","timestamp":1287792000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Mol Hist"],"published-print":{"date-parts":[[2010,12]]},"DOI":"10.1007\/s10735-010-9287-1","type":"journal-article","created":{"date-parts":[[2010,10,22]],"date-time":"2010-10-22T01:15:11Z","timestamp":1287710111000},"page":"309-314","source":"Crossref","is-referenced-by-count":30,"title":["The role of epidermal growth factor in the healing tympanic membrane following perforation in rats"],"prefix":"10.1007","volume":"41","author":[{"given":"Peter L.","family":"Santa Maria","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharon L.","family":"Redmond","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcus D.","family":"Atlas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reza","family":"Ghassemifar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2010,10,23]]},"reference":[{"issue":"11","key":"9287_CR1","doi-asserted-by":"crossref","first-page":"3970","DOI":"10.1016\/S0021-9258(17)34785-3","volume":"253","author":"A Aharonov","year":"1978","unstructured":"Aharonov A, Pruss RM et al (1978) Epidermal growth factor. relationship between receptor regulation and mitogenesis in 3T3 cells. J Biol Chem 253(11):3970\u20133977","journal-title":"J Biol Chem"},{"issue":"6","key":"9287_CR2","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1016\/S0002-9610(05)80797-4","volume":"165","author":"NT Bennett","year":"1993","unstructured":"Bennett NT, Schultz GS (1993a) Growth factors and wound healing: biochemical properties of growth factors and their receptors. Am J Surg 165(6):728\u2013737","journal-title":"Am J Surg"},{"issue":"1","key":"9287_CR3","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/S0002-9610(05)80589-6","volume":"166","author":"NT Bennett","year":"1993","unstructured":"Bennett NT, Schultz GS (1993b) Growth factors and wound healing: part II. Role in normal and chronic wound healing. Am J Surg 166(1):74\u201381","journal-title":"Am J Surg"},{"issue":"1","key":"9287_CR4","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0194-5998(99)70122-1","volume":"121","author":"K Chauvin","year":"1999","unstructured":"Chauvin K, Bratton C et al (1999) Healing large tympanic membrane perforations using hyaluronic acid, basic fibroblast growth factor, and epidermal growth factor. Otolaryngol Head Neck Surg 121(1):43\u201347","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"10","key":"9287_CR5","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1177\/000348948909801002","volume":"98","author":"RA Chole","year":"1989","unstructured":"Chole RA, Kodama K (1989) Comparative histology of the tympanic membrane and its relationship to cholesteatoma. Ann Otol Rhinol Laryngol 98(10):761\u2013766","journal-title":"Ann Otol Rhinol Laryngol"},{"issue":"12 Pt 1","key":"9287_CR6","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1288\/00005537-199512000-00007","volume":"105","author":"DW Dvorak","year":"1995","unstructured":"Dvorak DW, Abbas G et al (1995) Repair of chronic tympanic membrane perforations with long-term epidermal growth factor. Laryngoscope 105(12 Pt 1):1300\u20131304","journal-title":"Laryngoscope"},{"issue":"1","key":"9287_CR7","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1093\/nar\/30.1.207","volume":"30","author":"R Edgar","year":"2002","unstructured":"Edgar R, Domrachev M et al (2002) Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res 30(1):207\u2013210","journal-title":"Nucleic Acids Res"},{"issue":"5","key":"9287_CR8","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/S0030-6665(20)30467-9","volume":"28","author":"HB Gladstone","year":"1995","unstructured":"Gladstone HB, Jackler RK et al (1995) Tympanic membrane wound healing. An overview. Otolaryngol Clin North Am 28(5):913\u2013932","journal-title":"Otolaryngol Clin North Am"},{"issue":"3","key":"9287_CR9","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1097\/00129492-200305000-00004","volume":"24","author":"EA Guneri","year":"2003","unstructured":"Guneri EA, Tekin S et al (2003) The effects of hyaluronic acid, epidermal growth factor, and mitomycin in an experimental model of acute traumatic tympanic membrane perforation. Otol Neurotol 24(3):371\u2013376","journal-title":"Otol Neurotol"},{"issue":"5","key":"9287_CR10","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1016\/S0030-6665(20)30468-0","volume":"28","author":"DB Hom","year":"1995","unstructured":"Hom DB (1995) Growth factors in wound healing. Otolaryngol Clin North Am 28(5):933\u2013953","journal-title":"Otolaryngol Clin North Am"},{"issue":"3","key":"9287_CR11","doi-asserted-by":"crossref","first-page":"181","DOI":"10.3109\/00016486809126286","volume":"66","author":"DJ Lim","year":"1968","unstructured":"Lim DJ (1968a) Tympanic membrane. Electron microscopic observation. I: pars tensa. Acta Otolaryngol 66(3):181\u2013198","journal-title":"Acta Otolaryngol"},{"issue":"6","key":"9287_CR12","doi-asserted-by":"crossref","first-page":"515","DOI":"10.3109\/00016486809126316","volume":"66","author":"DJ Lim","year":"1968","unstructured":"Lim DJ (1968b) Tympanic membrane. II. Pars flaccida. Acta Otolaryngol 66(6):515\u2013532","journal-title":"Acta Otolaryngol"},{"issue":"6","key":"9287_CR13","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1080\/000164802320396259","volume":"122","author":"Y Ma","year":"2002","unstructured":"Ma Y, Zhao H et al (2002) Topical treatment with growth factors for tympanic membrane perforations: progress towards clinical application. Acta Otolaryngol 122(6):586\u2013599","journal-title":"Acta Otolaryngol"},{"issue":"3","key":"9287_CR14","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/S0094-1298(20)30617-9","volume":"17","author":"MH McGrath","year":"1990","unstructured":"McGrath MH (1990) Peptide growth factors and wound healing. Clin Plast Surg 17(3):421\u2013432","journal-title":"Clin Plast Surg"},{"issue":"1","key":"9287_CR15","doi-asserted-by":"crossref","first-page":"50","DOI":"10.3109\/00016489509133346","volume":"115","author":"M Mondain","year":"1995","unstructured":"Mondain M, Ryan A (1995) Epidermal growth factor and basic fibroblast growth factor are induced in guinea-pig tympanic membrane following traumatic perforation. Acta Otolaryngol 115(1):50\u201354","journal-title":"Acta Otolaryngol"},{"issue":"3","key":"9287_CR16","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1002\/jcp.1041450323","volume":"145","author":"T Nishida","year":"1990","unstructured":"Nishida T, Nakamura M et al (1990) Differential modes of action of fibronectin and epidermal growth factor on rabbit corneal epithelial migration. J Cell Physiol 145(3):549\u2013554","journal-title":"J Cell Physiol"},{"issue":"1","key":"9287_CR17","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1177\/000348949009900114","volume":"99","author":"TG O\u2019Daniel","year":"1990","unstructured":"O\u2019Daniel TG, Petitjean M et al (1990) Epidermal growth factor binding and action on tympanic membranes. Ann Otol Rhinol Laryngol 99(1):80\u201384","journal-title":"Ann Otol Rhinol Laryngol"},{"issue":"9","key":"9287_CR18","doi-asserted-by":"crossref","first-page":"e45","DOI":"10.1093\/nar\/29.9.e45","volume":"29","author":"MW Pfaffl","year":"2001","unstructured":"Pfaffl MW (2001) A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29(9):e45","journal-title":"Nucleic Acids Res"},{"issue":"4","key":"9287_CR19","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/S0194-5998(95)70071-4","volume":"113","author":"HA Ramsay","year":"1995","unstructured":"Ramsay HA, Heikkonen EJ et al (1995) Effect of epidermal growth factor on tympanic membranes with chronic perforations: a clinical trial. Otolaryngol Head Neck Surg 113(4):375\u2013379","journal-title":"Otolaryngol Head Neck Surg"},{"key":"9287_CR20","unstructured":"Rasband WS (1997\u20132004) ImageJ software. National Institutes of Health, Bethesda, MD, USA. from http:\/\/rsb.info.nih.gov\/ij\/"},{"issue":"4","key":"9287_CR21","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/0738-081X(91)90084-X","volume":"9","author":"MJ Rothe","year":"1991","unstructured":"Rothe MJ, Falanga V (1991) Growth factors and wound healing. Clin Dermatol 9(4):553\u2013559","journal-title":"Clin Dermatol"},{"key":"9287_CR26","doi-asserted-by":"crossref","unstructured":"Santa Maria PL, Redmond SL, Atlas MD, Ghassemifar R (2010) Histology of the healing tympanic membrane following perforations in rats. Laryngoscope 120(10):2061\u20132070","DOI":"10.1002\/lary.20998"},{"issue":"1","key":"9287_CR22","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1159\/000276181","volume":"53","author":"SH Schmidt","year":"1991","unstructured":"Schmidt SH, Hellstrom S (1991) Tympanic-membrane structure\u2013new views. A comparative study. ORL J Otorhinolaryngol Relat Spec 53(1):32\u201336","journal-title":"ORL J Otorhinolaryngol Relat Spec"},{"issue":"3","key":"9287_CR23","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/1471-2199-7-3","volume":"7","author":"A Schroeder","year":"2006","unstructured":"Schroeder A, Mueller O et al (2006) The RIN: an RNA integrity number for assigning integrity values to RNA measurements. BMC Mol Biol 7(3):3","journal-title":"BMC Mol Biol"},{"issue":"2","key":"9287_CR24","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1083\/jcb.151.2.209","volume":"151","author":"S Tokumaru","year":"2000","unstructured":"Tokumaru S, Higashiyama S et al (2000) Ectodomain shedding of epidermal growth factor receptor ligands is required for keratinocyte migration in cutaneous wound healing. J Cell Biol 151(2):209\u2013220","journal-title":"J Cell Biol"},{"key":"9287_CR25","doi-asserted-by":"crossref","unstructured":"Vandesompele J, De Preter K et al. (2002) Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 3(7): RESEARCH0034","DOI":"10.1186\/gb-2002-3-7-research0034"}],"container-title":["Journal of Molecular Histology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10735-010-9287-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10735-010-9287-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10735-010-9287-1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,31]],"date-time":"2024-03-31T17:15:41Z","timestamp":1711905341000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10735-010-9287-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,10,23]]},"references-count":26,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2010,12]]}},"alternative-id":["9287"],"URL":"https:\/\/doi.org\/10.1007\/s10735-010-9287-1","relation":{},"ISSN":["1567-2379","1567-2387"],"issn-type":[{"value":"1567-2379","type":"print"},{"value":"1567-2387","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,10,23]]}}}