{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T08:02:15Z","timestamp":1772006535130,"version":"3.50.1"},"reference-count":96,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T00:00:00Z","timestamp":1766966400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T00:00:00Z","timestamp":1766966400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Mol Histol"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1007\/s10735-025-10659-1","type":"journal-article","created":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T14:20:31Z","timestamp":1767018031000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Protective effect of Carica papaya leaf extract against dental pulp damage induced by gamma irradiation"],"prefix":"10.1007","volume":"57","author":[{"given":"Saher S.","family":"Mohammed","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amany E.","family":"Ragab","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanaa M.","family":"Hassan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Walied","family":"Abdo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Magda E.","family":"Mahmoud","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ibrahim Y.","family":"Abdelrahman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asmaa M.","family":"Abdeen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,12,29]]},"reference":[{"issue":"1","key":"10659_CR1","doi-asserted-by":"publisher","first-page":"111","DOI":"10.21608\/ejhm.2005.18115","volume":"19","author":"NAR Abdel Motaal","year":"2005","unstructured":"Abdel Motaal NAR, Abdel Maguid A (2005) Effect of fractionated and single doses gamma irradiation on certain mammalian organs. Egypt J Hosp Med 19(1):111\u2013122. https:\/\/doi.org\/10.21608\/ejhm.2005.18115","journal-title":"Egypt J Hosp Med"},{"issue":"4","key":"10659_CR2","first-page":"39","volume":"53","author":"IY Abdelrahman","year":"2020","unstructured":"Abdelrahman IY, El-Kashef H, Hassan NHJA (2020) Anti-tumor effect of green tea extract, simvastatin and gamma radiation on solid tumor in mice. JoNS, Applications 53(4):39\u201352","journal-title":"JoNS, Applications"},{"key":"10659_CR3","doi-asserted-by":"crossref","unstructured":"A\u011eALAR H, Ciftci G, G\u00f6ger F, KIRIMER N (2018) Activity guided fractionation of Arum italicum miller tubers and the LC\/MS-MS profiles. Records of Natural Products 12 (1)","DOI":"10.25135\/rnp.06.17.05.089"},{"issue":"2","key":"10659_CR4","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1016\/S0308-8146(00)00324-1","volume":"73","author":"MB Arnao","year":"2001","unstructured":"Arnao MB, Cano A, Acosta M (2001) The hydrophilic and lipophilic contribution to total antioxidant activity. Food Chem 73(2):239\u2013244","journal-title":"Food Chem"},{"issue":"1","key":"10659_CR5","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s13065-016-0149-0","volume":"10","author":"N Asghar","year":"2016","unstructured":"Asghar N, Naqvi SAR, Hussain Z, Rasool N, Khan ZA, Shahzad SA, Sherazi TA, Janjua MRSA, Nagra SA, Zia-Ul-Haq M (2016) Compositional difference in antioxidant and antibacterial activity of all parts of the Carica papaya using different solvents. Chem Cent J 10(1):1\u201311","journal-title":"Chem Cent J"},{"key":"10659_CR6","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1186\/s12906-015-0749-6","volume":"15","author":"J Aziz","year":"2015","unstructured":"Aziz J, Abu Kassim NL, Abu Kasim NH, Haque N, Rahman MT (2015) Carica papaya induces in vitro thrombopoietic cytokines secretion by mesenchymal stem cells and haematopoietic cells. BMC Complement Altern Med 15:215. https:\/\/doi.org\/10.1186\/s12906-015-0749-6","journal-title":"BMC Complement Altern Med"},{"issue":"1","key":"10659_CR7","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1007\/s40199-022-00435-x","volume":"30","author":"SR Bahoosh","year":"2022","unstructured":"Bahoosh SR, Shokoohinia Y, Eftekhari M (2022) Glucosinolates and their hydrolysis products as potential nutraceuticals to combat cytokine storm in SARS-COV-2. DARU J Pharm Sci 30(1):245\u2013252","journal-title":"DARU J Pharm Sci"},{"issue":"7","key":"10659_CR8","doi-asserted-by":"publisher","first-page":"821","DOI":"10.1177\/002215540104900703","volume":"49","author":"KL Barrett","year":"2001","unstructured":"Barrett KL, Willingham JM, Garvin AJ, Willingham MC (2001) Advances in cytochemical methods for detection of apoptosis. J Histochem Cytochem 49(7):821\u2013832. https:\/\/doi.org\/10.1177\/002215540104900703","journal-title":"J Histochem Cytochem"},{"issue":"1","key":"10659_CR9","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1006\/abio.1996.0292","volume":"239","author":"IF Benzie","year":"1996","unstructured":"Benzie IF, Strain JJ (1996) The ferric reducing ability of plasma (FRAP) as a measure of \u201cantioxidant power\u201d: the FRAP assay. Anal Biochem 239(1):70\u201376","journal-title":"Anal Biochem"},{"issue":"1","key":"10659_CR10","first-page":"29","volume":"8","author":"R Boly","year":"2016","unstructured":"Boly R, Lamkami T, Lompo M, Dubois J, Guissou I (2016) DPPH free radical scavenging activity of two extracts from Agelanthus dodoneifolius (Loranthaceae) leaves. Int J Toxicol Pharmacol Res 8(1):29\u201334","journal-title":"Int J Toxicol Pharmacol Res"},{"key":"10659_CR11","doi-asserted-by":"publisher","unstructured":"Bouten RM, Young EF, Selwyn R, Iacono D, Rittase WB, Day RM (2021) Chapter Two - Effects of radiation on endothelial barrier and vascular integrity. In: Gorbunov NV (ed) Tissue Barriers in Disease, Injury and Regeneration. Elsevier, pp 43\u201394. https:\/\/doi.org\/10.1016\/B978-0-12-818561-2.00007-2","DOI":"10.1016\/B978-0-12-818561-2.00007-2"},{"key":"10659_CR12","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1016\/j.indcrop.2015.01.051","volume":"67","author":"MC Bowyer","year":"2015","unstructured":"Bowyer MC, Van Vuong Q, Van Altena IA, Scarlett CJ (2015) Phytochemicals and antioxidant capacity of Xao tam phan (Paramignya trimera) root as affected by various solvents and extraction methods. Ind Crops Prod 67:192\u2013200. https:\/\/doi.org\/10.1016\/j.indcrop.2015.01.051","journal-title":"Ind Crops Prod"},{"issue":"4","key":"10659_CR13","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1667\/RR2461.1","volume":"175","author":"M Buonanno","year":"2011","unstructured":"Buonanno M, de Toledo SM, Pain D, Azzam EI (2011) Long-term consequences of radiation-induced bystander effects depend on radiation quality and dose and correlate with oxidative stress. Radiat Res 175(4):405\u2013415","journal-title":"Radiat Res"},{"issue":"7","key":"10659_CR14","doi-asserted-by":"publisher","first-page":"584","DOI":"10.1016\/j.jfca.2007.03.009","volume":"20","author":"A Canini","year":"2007","unstructured":"Canini A, Alesiani D, D\u2019Arcangelo G, Tagliatesta P (2007) Gas chromatography\u2013mass spectrometry analysis of phenolic compounds from Carica papaya L. leaf. J Food Compos Anal 20(7):584\u2013590","journal-title":"J Food Compos Anal"},{"key":"10659_CR15","doi-asserted-by":"crossref","unstructured":"Chang C-C, Yang M-H, Wen H-M, Chern J-C (2002) Estimation of total flavonoid content in propolis by two complementary colorimetric methods. Journal of food and drug analysis 10 (3)","DOI":"10.38212\/2224-6614.2748"},{"issue":"1","key":"10659_CR16","doi-asserted-by":"publisher","first-page":"414","DOI":"10.1016\/j.foodchem.2012.11.001","volume":"138","author":"Z Chen","year":"2013","unstructured":"Chen Z, Bertin R, Froldi G (2013) EC50 estimation of antioxidant activity in DPPH assay using several statistical programs. Food Chem 138(1):414\u2013420","journal-title":"Food Chem"},{"issue":"3","key":"10659_CR17","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1076\/1388-0209(200007)3831-SFT222","volume":"38","author":"I Chevalley","year":"2000","unstructured":"Chevalley I, Marston A, Hostettmann K (2000) New phenolic radical scavengers from Saxifraga cuneifolia. Pharm Biol 38(3):222\u2013228","journal-title":"Pharm Biol"},{"issue":"11","key":"10659_CR18","doi-asserted-by":"publisher","first-page":"1696","DOI":"10.3390\/antiox10111696","volume":"10","author":"S-S Choi","year":"2021","unstructured":"Choi S-S, Park H-R, Lee K-A (2021) A comparative study of rutin and rutin glycoside: antioxidant activity, anti-inflammatory effect, effect on platelet aggregation and blood coagulation. Antioxidants 10(11):1696","journal-title":"Antioxidants"},{"issue":"5","key":"10659_CR19","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1667\/RR1629.1","volume":"173","author":"SW Chung","year":"2010","unstructured":"Chung SW, Kim JM, Kim DH, Kim JY, Lee EK, Anton S, Jeong KS, Lee J, Yoo MA, Kim YJ (2010) Molecular delineation of \u03b3-ray-induced NF-\u03baB activation and pro-inflammatory genes in SMP30 knockout mice. Radiat Res 173(5):629\u2013634","journal-title":"Radiat Res"},{"issue":"4","key":"10659_CR20","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1111\/j.1834-7819.2008.00080.x","volume":"53","author":"JE Clarkson","year":"2008","unstructured":"Clarkson JE, Worthington HV, Eden OB (2008) Interventions for treating oral mucositis for patients with cancer receiving treatment. Aust Dent J 53(4):363\u2013365. https:\/\/doi.org\/10.1111\/j.1834-7819.2008.00080.x","journal-title":"Aust Dent J"},{"issue":"9","key":"10659_CR21","doi-asserted-by":"publisher","first-page":"1210","DOI":"10.1136\/gut.34.9.1210","volume":"34","author":"A Cole","year":"1993","unstructured":"Cole A, Slater K, Sokal M, Hawkey C (1993) In vivo rectal inflammatory mediator changes with radiotherapy to the pelvis. Gut 34(9):1210\u20131214","journal-title":"Gut"},{"key":"10659_CR22","doi-asserted-by":"crossref","unstructured":"Cole A, Slater K, Sokal M, Filipowicz B, Kurlak L, Hawkey C Elevated Rectal Leukotriene B 4, Thromboxane B 2 and Prostaglandin E 2 Levels in Patients Having Pelvic Radiotherapy. In: Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation and Radiation Injury: Proceedings of the 2nd International Conference September 17\u201321, 1991 Berlin, FRG, 1993a. Springer, pp 771\u2013773","DOI":"10.1007\/978-1-4615-3520-1_149"},{"key":"10659_CR23","unstructured":"Council N (2011) Guide fo the Care and Use of Laboratory Animals: Eight Edition. Tha National Academies Press, Washington, DC[Google Scholar]"},{"key":"10659_CR24","unstructured":"De S, Rr L, Vabeiryureilai M, Senthil N, Lalnunmawii E (2015) An investigation of the antioxidant property of Carica papaya leaf extracts from Mizoram, Northeast India. Research & Reviews: Journal of BotanicalSciences"},{"issue":"4","key":"10659_CR25","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1016\/S0024-3205(99)00120-4","volume":"65","author":"G Di Carlo","year":"1999","unstructured":"Di Carlo G, Mascolo N, Izzo AA, Capasso F (1999) Flavonoids: old and new aspects of a class of natural therapeutic drugs. Life Sci 65(4):337\u2013353","journal-title":"Life Sci"},{"issue":"3","key":"10659_CR26","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1007\/s00411-013-0469-6","volume":"52","author":"N El-Faramawy","year":"2013","unstructured":"El-Faramawy N, Ameen R, El-Haddad K, El-Zainy M (2013) Effects of gamma radiation on hard dental tissues of albino rats: investigation by light microscopy. Radiat Environ Biophys 52(3):375\u2013387. https:\/\/doi.org\/10.1007\/s00411-013-0469-6","journal-title":"Radiat Environ Biophys"},{"issue":"Issue 2 - April","key":"10659_CR27","doi-asserted-by":"publisher","first-page":"1315","DOI":"10.21608\/edj.2018.77388","volume":"64","author":"KE-S El-Haddad","year":"2018","unstructured":"El-Haddad KE-S, Metwaly HAM (2018) Evaluation of dose dependent effects of gamma radiation on rat tongue internal structures: histomorphometric and immunohistochemical study. Egypt Dent J 64(Issue 2-April (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)):1315\u20131325. https:\/\/doi.org\/10.21608\/edj.2018.77388","journal-title":"Egypt Dent J"},{"key":"10659_CR28","doi-asserted-by":"crossref","unstructured":"El-Shazly MA, Hamed AA, Kabary HA, Ghareeb MA (2021) LC-MS\/MS profiling, antibiofilm, antimicrobial and bacterial growth kinetic studies of Pluchea dioscoridis extracts. Acta Chromatographica","DOI":"10.1556\/1326.2021.00956"},{"key":"10659_CR29","volume-title":"Radiation pathology","author":"LF Fajardo","year":"2001","unstructured":"Fajardo LF, Berthrong M, Anderson RE (2001) Radiation pathology. Oxford University Press"},{"key":"10659_CR30","doi-asserted-by":"publisher","DOI":"10.1590\/S0001-37652013005000009","author":"SC Ferreira-Machado","year":"2013","unstructured":"Ferreira-Machado SC, Salata C, Rocha NN, Corr\u00eaa AFS, C\u00f4rte-Real S, Peregrino AAF, Campos VMAd, Andrade CBV, Bernardo-Filho M, Cabral-Neto JB, Dealmeida CE (2013) Caspase-3 activation and increased procollagen type I in irradiated hearts. An Acad Bras Cienc. https:\/\/doi.org\/10.1590\/S0001-37652013005000009","journal-title":"An Acad Bras Cienc"},{"issue":"3","key":"10659_CR31","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1016\/s1079-2104(99)70044-2","volume":"88","author":"M Goldstein","year":"1999","unstructured":"Goldstein M, Maxymiw WG, Cummings BJ, Wood RE (1999) The effects of antitumor irradiation on mandibular opening and mobility: a prospective study of 58 patients. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 88(3):365\u2013373. https:\/\/doi.org\/10.1016\/s1079-2104(99)70044-2","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"issue":"3","key":"10659_CR32","doi-asserted-by":"publisher","DOI":"10.1016\/j.phyplu.2022.100306","volume":"2","author":"CNFL Gondim","year":"2022","unstructured":"Gondim CNFL, Bezerra DAC, Sampaio NFL, de Alencar MAS, da Costa RHS, Abreu LS, Junior FNP, Tavares JF, da Silva MS, Ribeiro-Filho J (2022) HPLC-DAD-ESI-MS profile, antibacterial activity, and modulation of the activity of antibiotics by Carica papaya L. against Escherichia coli serotypes. Phytomedicine plus 2(3):100306","journal-title":"Phytomedicine plus"},{"issue":"2","key":"10659_CR33","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1016\/j.jpba.2006.08.005","volume":"43","author":"R Govindarajan","year":"2007","unstructured":"Govindarajan R, Singh D, Rawat A (2007) High-performance liquid chromatographic method for the quantification of phenolics in \u2018Chyavanprash\u2019a potent Ayurvedic drug. J Pharm Biomed Anal 43(2):527\u2013532","journal-title":"J Pharm Biomed Anal"},{"issue":"4","key":"10659_CR34","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1177\/002215540205000401","volume":"50","author":"AM Gown","year":"2002","unstructured":"Gown AM, Willingham MC (2002) Improved detection of apoptotic cells in archival paraffin sections: immunohistochemistry using antibodies to cleaved caspase 3. J Histochem Cytochem 50(4):449\u2013454. https:\/\/doi.org\/10.1177\/002215540205000401","journal-title":"J Histochem Cytochem"},{"issue":"1","key":"10659_CR35","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/s0092-8674(00)00003-9","volume":"102","author":"DR Green","year":"2000","unstructured":"Green DR (2000) Apoptotic pathways: paper wraps stone blunts scissors. Cell 102(1):1\u20134. https:\/\/doi.org\/10.1016\/s0092-8674(00)00003-9","journal-title":"Cell"},{"issue":"11","key":"10659_CR36","doi-asserted-by":"publisher","first-page":"3845","DOI":"10.1096\/fj.201600620R","volume":"30","author":"M Halle","year":"2016","unstructured":"Halle M, Christersdottir T, B\u00e4ck M (2016) Chronic adventitial inflammation, vasa vasorum expansion, and 5-lipoxygenase up-regulation in irradiated arteries from cancer survivors. FASEB J 30(11):3845","journal-title":"FASEB J"},{"key":"10659_CR37","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1007\/BF01569740","volume":"9","author":"CT Hou","year":"1992","unstructured":"Hou CT, Bagby MO (1992) 10-hydroxy-8 (Z)-octadecenoic acid, an intermediate in the bioconversion of oleic acid to 7, 10-dihydroxy-8 (E)-octadecenoic acid. J Ind Microbiol 9:103\u2013107","journal-title":"J Ind Microbiol"},{"key":"10659_CR38","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2020.153400","volume":"80","author":"W-H Hu","year":"2021","unstructured":"Hu W-H, Dai DK, Zheng BZ-Y, Duan R, Chan GK-L, Dong TT-X, Qin Q-W, Tsim KW-K (2021) The binding of kaempferol-3-O-rutinoside to vascular endothelial growth factor potentiates anti-inflammatory efficiencies in lipopolysaccharide-treated mouse macrophage RAW264. 7 cells. Phytomedicine 80:153400","journal-title":"Phytomedicine"},{"issue":"6","key":"10659_CR39","doi-asserted-by":"publisher","first-page":"1841","DOI":"10.1021\/jf030723c","volume":"53","author":"D Huang","year":"2005","unstructured":"Huang D, Ou B, Prior RL (2005) The chemistry behind antioxidant capacity assays. J Agric Food Chem 53(6):1841\u20131856","journal-title":"J Agric Food Chem"},{"issue":"9","key":"10659_CR40","doi-asserted-by":"publisher","first-page":"792","DOI":"10.1177\/0022034509340867","volume":"88","author":"GT Huang","year":"2009","unstructured":"Huang GT, Gronthos S, Shi S (2009) Mesenchymal stem cells derived from dental tissues vs. those from other sources: their biology and role in regenerative medicine. J Dent Res 88(9):792\u2013806. https:\/\/doi.org\/10.1177\/0022034509340867","journal-title":"J Dent Res"},{"issue":"7","key":"10659_CR41","doi-asserted-by":"publisher","first-page":"860","DOI":"10.1038\/nm.2385","volume":"17","author":"Q Huang","year":"2011","unstructured":"Huang Q, Li F, Liu X, Li W, Shi W, Liu FF, O\u2019Sullivan B, He Z, Peng Y, Tan AC, Zhou L, Shen J, Han G, Wang XJ, Thorburn J, Thorburn A, Jimeno A, Raben D, Bedford JS, Li CY (2011) Caspase 3-mediated stimulation of tumor cell repopulation during cancer radiotherapy. Nat Med 17(7):860\u2013866. https:\/\/doi.org\/10.1038\/nm.2385","journal-title":"Nat Med"},{"key":"10659_CR42","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2023.1218015","author":"J Huang","year":"2023","unstructured":"Huang J, Xie M, He L, Song X, Cao T (2023) Chlorogenic acid: a review on its mechanisms of anti-inflammation, disease treatment, and related delivery systems. Front Pharmacol. https:\/\/doi.org\/10.3389\/fphar.2023.1218015","journal-title":"Front Pharmacol"},{"key":"10659_CR43","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.phymed.2017.04.009","volume":"32","author":"A Inam","year":"2017","unstructured":"Inam A, Shahzad M, Shabbir A, Shahid H, Shahid K, Javeed A (2017) Carica papaya ameliorates allergic asthma via down regulation of IL-4, IL-5, eotaxin, TNF-\u03b1, NF-\u0138B, and iNOS levels. Phytomedicine 32:1\u20137","journal-title":"Phytomedicine"},{"issue":"2","key":"10659_CR44","first-page":"267","volume":"23","author":"M Indran","year":"1991","unstructured":"Indran M, Carr K, Gilmore R, Boyle F (1991) Mucosal changes in mouse duodenum after gamma-irradiation or reserpine treatment. J Submicrosc Cytol Pathol 23(2):267\u2013278","journal-title":"J Submicrosc Cytol Pathol"},{"key":"10659_CR45","doi-asserted-by":"crossref","unstructured":"Ismail Z, Halim SZ, Abdullah NR, Afzan A, Abdul Rashid BA, Jantan I (2014) Safety evaluation of oral toxicity of Carica papaya Linn. leaves: a subchronic toxicity study in sprague dawley rats. Evidence-Based Complementary and Alternative Medicine 2014","DOI":"10.1155\/2014\/741470"},{"issue":"3","key":"10659_CR46","first-page":"225","volume":"22","author":"N Kahkeshani","year":"2019","unstructured":"Kahkeshani N, Farzaei F, Fotouhi M, Alavi SS, Bahramsoltani R, Naseri R, Momtaz S, Abbasabadi Z, Rahimi R, Farzaei MH (2019) Pharmacological effects of gallic acid in health and diseases: a mechanistic review. Iran J Basic Med Sci 22(3):225","journal-title":"Iran J Basic Med Sci"},{"issue":"1","key":"10659_CR47","doi-asserted-by":"publisher","first-page":"1","DOI":"10.32807\/jkp.v15i1.399","volume":"15","author":"L Kamilla","year":"2021","unstructured":"Kamilla L, Tumpuk S, Salim M (2021) Anti-inflammatory of papaya leaf extract (Carica papaya L) towards membrane stabilization of red blood cells. Jurnal Kesehatan Prima 15(1):1\u20137","journal-title":"Jurnal Kesehatan Prima"},{"issue":"3","key":"10659_CR48","doi-asserted-by":"publisher","first-page":"149","DOI":"10.4103\/jphi.JPHI_60_17","volume":"7","author":"N Karimi","year":"2017","unstructured":"Karimi N, Monfared AS, Haddadi GH, Soleymani A, Mohammadi E, Hajian-Tilaki K, Borzoueisileh S (2017) Radioprotective effect of hesperidin on reducing oxidative stress in the lens tissue of rats. Int J Pharm Investig 7(3):149","journal-title":"Int J Pharm Investig"},{"issue":"2","key":"10659_CR49","first-page":"14","volume":"1","author":"S Khamsah","year":"2006","unstructured":"Khamsah S, Akowah G, Zhari I (2006) Antioxidant activity and phenolic content of Orthosiphon stamineus benth from different geographical origin. J Sustain Sci Manag 1(2):14\u201320","journal-title":"J Sustain Sci Manag"},{"issue":"5","key":"10659_CR50","doi-asserted-by":"publisher","first-page":"1489","DOI":"10.3390\/molecules26051489","volume":"26","author":"B-K Khor","year":"2021","unstructured":"Khor B-K, Chear NJ-Y, Azizi J, Khaw K-Y (2021a) Chemical composition, antioxidant and cytoprotective potentials of Carica papaya leaf extracts: a comparison of supercritical fluid and conventional extraction methods. Molecules 26(5):1489","journal-title":"Molecules"},{"key":"10659_CR51","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26051489","author":"B-K Khor","year":"2021","unstructured":"Khor B-K, Chear NJ, Azizi J, Khaw K-Y (2021b) Chemical composition, antioxidant and cytoprotective potentials of Carica papaya leaf extracts: a comparison of supercritical fluid and conventional extraction methods. Molecules. https:\/\/doi.org\/10.3390\/molecules26051489","journal-title":"Molecules"},{"issue":"4","key":"10659_CR52","first-page":"283","volume":"37","author":"R Kumar","year":"2018","unstructured":"Kumar R, Chauhan SK, Shinde G, Subramanian V, Nadanasabapathi S (2018) Whey proteins: a potential ingredient for food industry-a review. Asian J Dairy Food Res 37(4):283\u2013290","journal-title":"Asian J Dairy Food Res"},{"issue":"1","key":"10659_CR53","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1016\/j.cden.2007.10.002","volume":"52","author":"RV Lalla","year":"2008","unstructured":"Lalla RV, Sonis ST, Peterson DE (2008) Management of oral mucositis in patients who have cancer. Dent Clin North Am 52(1):61\u201377. https:\/\/doi.org\/10.1016\/j.cden.2007.10.002","journal-title":"Dent Clin North Am"},{"issue":"2","key":"10659_CR54","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1016\/j.seppur.2005.07.005","volume":"48","author":"B Li","year":"2006","unstructured":"Li B, Smith B, Hossain MM (2006) Extraction of phenolics from citrus peels: I. solvent extraction method. Sep Purif Technol 48(2):182\u2013188","journal-title":"Sep Purif Technol"},{"issue":"11","key":"10659_CR55","doi-asserted-by":"publisher","first-page":"19180","DOI":"10.3390\/molecules191119180","volume":"19","author":"N Liang","year":"2014","unstructured":"Liang N, Kitts DD (2014) Antioxidant property of coffee components: assessment of methods that define mechanisms of action. Molecules 19(11):19180\u201319208","journal-title":"Molecules"},{"issue":"1","key":"10659_CR56","doi-asserted-by":"publisher","first-page":"5441","DOI":"10.1038\/s41598-018-23748-x","volume":"8","author":"H Ma","year":"2018","unstructured":"Ma H, Li J, An M, Gao X-m, Chang Y-x (2018) A powerful on line ABTS+\u2013CE-DAD method to screen and quantify major antioxidants for quality control of Shuxuening Injection. Sci Rep 8(1):5441","journal-title":"Sci Rep"},{"issue":"1","key":"10659_CR57","doi-asserted-by":"publisher","first-page":"19","DOI":"10.4103\/1735-3327.201139","volume":"14","author":"ZS Madani","year":"2017","unstructured":"Madani ZS, Azarakhsh S, Shakib PA, Karimi M (2017) Histopathological changes in dental pulp of rats following radiotherapy. Dent Res J (Isfahan) 14(1):19\u201324. https:\/\/doi.org\/10.4103\/1735-3327.201139","journal-title":"Dent Res J (Isfahan)"},{"issue":"3","key":"10659_CR58","first-page":"1043","volume":"20","author":"A Maisarah","year":"2013","unstructured":"Maisarah A, Amira NB, Asmah R, Fauziah O (2013) Antioxidant analysis of different parts of Carica papaya. Int Food Res J 20(3):1043","journal-title":"Int Food Res J"},{"key":"10659_CR59","doi-asserted-by":"crossref","unstructured":"Malafaia O, Andreollo NA, Zilberstein B, Cecconello I (2014) ABCD-Arquivos Brasileiros de Cirurgia Digestiva: 1000 artigos e uma trajet\u00f3ria de vit\u00f3rias. vol 27. SciELO Brasil,","DOI":"10.1590\/S0102-67202014000200001"},{"issue":"1","key":"10659_CR60","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1016\/S0360-3016(03)00523-6","volume":"57","author":"M Moll\u00e0","year":"2003","unstructured":"Moll\u00e0 M, Gironella M, Miquel R, Tovar V, Engel P, Biete A, Piqu\u00e9 JM, Pan\u00e9s J (2003) Relative roles of ICAM-1 and VCAM-1 in the pathogenesis of experimental radiation-induced intestinal inflammation. Int J Radiat Oncol Biol Phys 57(1):264\u2013273","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"2","key":"10659_CR61","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1016\/j.foodchem.2004.07.028","volume":"92","author":"P Montoro","year":"2005","unstructured":"Montoro P, Braca A, Pizza C, De Tommasi N (2005) Structure\u2013antioxidant activity relationships of flavonoids isolated from different plant species. Food Chem 92(2):349\u2013355","journal-title":"Food Chem"},{"issue":"4","key":"10659_CR62","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1080\/09553002.2018.1440092","volume":"94","author":"M Najafi","year":"2018","unstructured":"Najafi M, Motevaseli E, Shirazi A, Geraily G, Rezaeyan A, Norouzi F, Rezapoor S, Abdollahi H (2018) Mechanisms of inflammatory responses to radiation and normal tissues toxicity: clinical implications. Int J Radiat Biol 94(4):335\u2013356","journal-title":"Int J Radiat Biol"},{"issue":"3","key":"10659_CR63","doi-asserted-by":"publisher","first-page":"13","DOI":"10.7897\/2230-8407.080328","volume":"8","author":"A Nariya","year":"2017","unstructured":"Nariya A, Jhala D (2017) Pharmacognostic study of Carica papaya leaf extract as inhibitors of reactive oxygen species. Int Res J Pharm 8(3):13\u201317","journal-title":"Int Res J Pharm"},{"key":"10659_CR64","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1016\/j.jep.2015.11.049","volume":"178","author":"NW Nghonjuyi","year":"2016","unstructured":"Nghonjuyi NW, Tiambo CK, Ta\u00efwe GS, Toukala JP, Lisita F, Juliano RS, Kimbi HK (2016) Acute and sub-chronic toxicity studies of three plants used in Cameroonian ethnoveterinary medicine: Aloe vera (L.) Burm. f. (Xanthorrhoeaceae) leaves, Carica papaya L. (Caricaceae) seeds or leaves, and Mimosa pudica L. (Fabaceae) leaves in Kabir chicks. J Ethnopharmacol 178:40\u201349","journal-title":"J Ethnopharmacol"},{"issue":"1","key":"10659_CR65","first-page":"305","volume":"46","author":"N Nour","year":"2012","unstructured":"Nour N, Hamza (2012) Protective effect of Carica papaya Linn against\u202f?-radiation-induced tissue damage in rats. Arab J Nucl Sci Appl 46(1):305\u2013312","journal-title":"Arab J Nucl Sci Appl"},{"issue":"3","key":"10659_CR66","first-page":"241","volume":"17","author":"AA Omonkhua","year":"2011","unstructured":"Omonkhua AA, Onoagbe IO (2011) Long-term hepatotoxicity and hypoglycaemic study of aqueous extracts of Carica papaya leaves on normal rabbits. Glob J Pure Appl Sci 17(3):241\u2013247","journal-title":"Glob J Pure Appl Sci"},{"issue":"5","key":"10659_CR67","doi-asserted-by":"publisher","first-page":"265","DOI":"10.3166\/phyto-2018-0096","volume":"17","author":"Y Peristiowati","year":"2019","unstructured":"Peristiowati Y, Puspitasari Y (2019) Effects of papaya leaf extract (Carica papaya L.) on cellular proliferation and apoptosis in cervical cancer mice model. Phytotherapie 17(5):265\u2013275","journal-title":"Phytotherapie"},{"issue":"3","key":"10659_CR68","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1016\/j.tox.2004.12.009","volume":"209","author":"NR Prasad","year":"2005","unstructured":"Prasad NR, Menon VP, Vasudev V, Pugalendi K (2005) Radioprotective effect of sesamol on \u03b3-radiation induced DNA damage, lipid peroxidation and antioxidants levels in cultured human lymphocytes. Toxicology 209(3):225\u2013235","journal-title":"Toxicology"},{"issue":"2","key":"10659_CR69","doi-asserted-by":"publisher","first-page":"997","DOI":"10.1016\/j.bmc.2006.10.030","volume":"15","author":"N Rajapakse","year":"2007","unstructured":"Rajapakse N, Kim M-M, Mendis E, Kim S-K (2007) Inhibition of free radical-mediated oxidation of cellular biomolecules by carboxylated chitooligosaccharides. Bioorg Med Chem 15(2):997\u20131003","journal-title":"Bioorg Med Chem"},{"key":"10659_CR70","unstructured":"Reed KA (2009) Identification of phenolic compounds from peanut skin using HPLC-MSn. Virginia Tech,"},{"issue":"1","key":"10659_CR71","first-page":"17","volume":"18","author":"UZ Said","year":"2005","unstructured":"Said UZ, Saada HN, Rezk RG (2005) Role of calcium pantothenate in recovery of radiation induced injury to mammalian organs. Egypt J Radiat Sci Appl 18(1):17\u201338","journal-title":"Egypt J Radiat Sci Appl"},{"issue":"4","key":"10659_CR72","doi-asserted-by":"publisher","first-page":"37","DOI":"10.3390\/antibiotics6040037","volume":"6","author":"EY Salih","year":"2017","unstructured":"Salih EY, Fyhrquist P, Abdalla AM, Abdelgadir AY, Kanninen M, Sipi M, Luukkanen O, Fahmi MK, Elamin MH, Ali HA (2017) LC-MS\/MS tandem mass spectrometry for analysis of phenolic compounds and pentacyclic triterpenes in antifungal extracts of Terminalia brownii (Fresen). Antibiotics 6(4):37","journal-title":"Antibiotics"},{"issue":"3","key":"10659_CR73","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1007\/s11418-014-0841-0","volume":"68","author":"E Salim","year":"2014","unstructured":"Salim E, Kumolosasi E, Jantan I (2014) Inhibitory effect of selected medicinal plants on the release of pro-inflammatory cytokines in lipopolysaccharide-stimulated human peripheral blood mononuclear cells. J Nat Med 68(3):647\u2013653. https:\/\/doi.org\/10.1007\/s11418-014-0841-0","journal-title":"J Nat Med"},{"issue":"Suppl_B","key":"10659_CR74","doi-asserted-by":"publisher","first-page":"B57","DOI":"10.1269\/jrr.47.B57","volume":"47","author":"K Sankaranarayanan","year":"2006","unstructured":"Sankaranarayanan K (2006) Estimation of the genetic risks of exposure to ionizing radiation in humans: current status and emerging perspectives. J Radiat Res 47(Suppl_B):B57\u2013B66","journal-title":"J Radiat Res"},{"issue":"5","key":"10659_CR75","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1016\/0964-1955(96)00037-1","volume":"32b","author":"C Scully","year":"1996","unstructured":"Scully C, Epstein JB (1996) Oral health care for the cancer patient. Eur J Cancer B Oral Oncol 32b(5):281\u2013292. https:\/\/doi.org\/10.1016\/0964-1955(96)00037-1","journal-title":"Eur J Cancer B Oral Oncol"},{"issue":"6","key":"10659_CR76","doi-asserted-by":"publisher","first-page":"1003","DOI":"10.1093\/jn\/128.6.1003","volume":"128","author":"M Serafini","year":"1998","unstructured":"Serafini M, Maiani G, Ferro-Luzzi A (1998) Alcohol-free red wine enhances plasma antioxidant capacity in humans. J Nutr 128(6):1003\u20131007","journal-title":"J Nutr"},{"issue":"3","key":"10659_CR77","doi-asserted-by":"publisher","first-page":"637","DOI":"10.1515\/jcim-2021-0568","volume":"19","author":"D Shanmugasundaram","year":"2022","unstructured":"Shanmugasundaram D, Roza JM (2022) Assessment of anti-inflammatory and antioxidant activity of quercetin\u2013rutin blend (SophorOx\u2122)\u2013an invitro cell based assay. J Complement Integr Med 19(3):637\u2013644","journal-title":"J Complement Integr Med"},{"key":"10659_CR78","doi-asserted-by":"publisher","unstructured":"Sharma A, Sharma R, Sharma M, Kumar M, Barbhai MD, Lorenzo JM, Sharma S, Samota MK, Atanassova M, Caruso G, Naushad M, Radha, Chandran D, Prakash P, Hasan M, Rais N, Dey A, Mahato DK, Dhumal S, Singh S, Senapathy M, Rajalingam S, Visvanathan M, Saleena LAK, Mekhemar M (2022a) Carica papaya L. Leaves: Deciphering Its Antioxidant Bioactives, Biological Activities, Innovative Products, and Safety Aspects. Oxid Med Cell Longev 2022:2451733. https:\/\/doi.org\/10.1155\/2022\/2451733","DOI":"10.1155\/2022\/2451733"},{"key":"10659_CR79","doi-asserted-by":"publisher","unstructured":"Sharma A, Sharma R, Sharma M, Kumar M, Barbhai MD, Lorenzo JM, Sharma S, Samota MK, Atanassova M, Caruso G, Naushad M, Radha, Chandran D, Prakash P, Hasan M, Rais N, Dey A, Mahato DK, Dhumal S, Singh S, Senapathy M, Rajalingam S, Visvanathan M, Saleena LAK, Mekhemar M (2022b) <i>Carica papaya<\/i>L. Leaves: Deciphering Its Antioxidant Bioactives, Biological Activities, Innovative Products, and Safety Aspects. Oxidative Medicine and Cellular Longevity 2022:2451733. https:\/\/doi.org\/10.1155\/2022\/2451733","DOI":"10.1155\/2022\/2451733"},{"issue":"8","key":"10659_CR80","doi-asserted-by":"publisher","first-page":"1086","DOI":"10.1016\/j.joen.2011.05.020","volume":"37","author":"Y Shigetani","year":"2011","unstructured":"Shigetani Y, Sasa N, Suzuki H, Okiji T, Ohshima H (2011) GaAlAs laser irradiation induces active tertiary dentin formation after pulpal apoptosis and cell proliferation in rat molars. J Endod 37(8):1086\u20131091. https:\/\/doi.org\/10.1016\/j.joen.2011.05.020","journal-title":"J Endod"},{"issue":"3","key":"10659_CR81","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1086\/physzool.24.3.30152119","volume":"24","author":"DE Smith","year":"1951","unstructured":"Smith DE, Svihla G, Patt HM (1951) The effects of X-radiation on circulation in the wing of the bat. Physiol Zool 24(3):249\u2013257","journal-title":"Physiol Zool"},{"issue":"3","key":"10659_CR82","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1177\/10454411980090030201","volume":"9","author":"AI Spielman","year":"1998","unstructured":"Spielman AI (1998) Chemosensory function and dysfunction. Crit Rev Oral Biol Med 9(3):267\u2013291. https:\/\/doi.org\/10.1177\/10454411980090030201","journal-title":"Crit Rev Oral Biol Med"},{"issue":"2","key":"10659_CR83","doi-asserted-by":"publisher","first-page":"92","DOI":"10.3164\/jcbn.40.92","volume":"40","author":"M Srinivasan","year":"2007","unstructured":"Srinivasan M, Sudheer AR, Menon VP (2007) Ferulic acid: therapeutic potential through its antioxidant property. J Clin Biochem Nutr 40(2):92\u2013100","journal-title":"J Clin Biochem Nutr"},{"issue":"2","key":"10659_CR84","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/s0165-3806(00)00041-9","volume":"121","author":"M Tanaka","year":"2000","unstructured":"Tanaka M, Momoi T, Marunouchi T (2000) In situ detection of activated caspase-3 in apoptotic granule neurons in the developing cerebellum in slice cultures and in vivo. Brain Res Dev Brain Res 121(2):223\u2013228. https:\/\/doi.org\/10.1016\/s0165-3806(00)00041-9","journal-title":"Brain Res Dev Brain Res"},{"issue":"1","key":"10659_CR85","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1046\/j.1525-1373.1999.d01-48.x","volume":"221","author":"SE Taylor","year":"1999","unstructured":"Taylor SE, Miller EG (1999) Preemptive pharmacologic intervention in radiation-induced salivary dysfunction. Proc Soc Exp Biol Med 221(1):14\u201326. https:\/\/doi.org\/10.1046\/j.1525-1373.1999.d01-48.x","journal-title":"Proc Soc Exp Biol Med"},{"issue":"1","key":"10659_CR86","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1097\/PRS.0b013e31821741d4","volume":"128","author":"CN Tchanque-Fossuo","year":"2011","unstructured":"Tchanque-Fossuo CN, Monson LA, Farberg AS, Donneys A, Zehtabzadeh AJ, Razdolsky ER, Buchman SR (2011) Dose-response effect of human equivalent radiation in the murine mandible. Part I. A histomorphometric assessment. Plast Reconstr Surg 128(1):114","journal-title":"Plast Reconstr Surg"},{"key":"10659_CR87","doi-asserted-by":"publisher","DOI":"10.1016\/j.prmcm.2023.100266","author":"EA Ugbogu","year":"2023","unstructured":"Ugbogu EA, Dike ED, Uche ME, Etumnu LR, Okoro BC, Ugbogu OC, Adurosakin OE, Chinma CE, Ohaeri E, Iweala EJ (2023) Ethnomedicinal uses, nutritional composition, phytochemistry and potential health benefits of Carica papaya. Pharmacological Res-Modern Chinese Med. https:\/\/doi.org\/10.1016\/j.prmcm.2023.100266","journal-title":"Pharmacological Res-Modern Chinese Med"},{"issue":"1","key":"10659_CR88","doi-asserted-by":"publisher","DOI":"10.1080\/23312025.2016.1247607","volume":"2","author":"V Vidya","year":"2016","unstructured":"Vidya V, Vishakh R, Shetty J, Peter AJ (2016) Radioprotective effects of diallyl disulphide and Carica papaya (L.) leaf extract in electron beam radiation induced hematopoietic suppression. Cogent Biol 2(1):1247607","journal-title":"Cogent Biol"},{"issue":"11","key":"10659_CR89","doi-asserted-by":"publisher","first-page":"859","DOI":"10.1111\/j.1365-2591.2007.01294.x","volume":"40","author":"FV Vier-Pelisser","year":"2007","unstructured":"Vier-Pelisser FV, Figueiredo MA, Cherubini K, Braga Filho A, Figueiredo JA (2007) The effect of head-fractioned teletherapy on pulp tissue. Int Endod J 40(11):859\u2013865. https:\/\/doi.org\/10.1111\/j.1365-2591.2007.01294.x","journal-title":"Int Endod J"},{"issue":"3","key":"10659_CR90","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1177\/154411130301400305","volume":"14","author":"A Vissink","year":"2003","unstructured":"Vissink A, Jansma J, Spijkervet FK, Burlage FR, Coppes RP (2003) Oral sequelae of head and neck radiotherapy. Crit Rev Oral Biol Med 14(3):199\u2013212. https:\/\/doi.org\/10.1177\/154411130301400305","journal-title":"Crit Rev Oral Biol Med"},{"key":"10659_CR91","volume-title":"Understanding radiation-induced vascular disease","author":"NL Weintraub","year":"2010","unstructured":"Weintraub NL, Jones WK, Manka D (2010) Understanding radiation-induced vascular disease, vol 55. American College of Cardiology Foundation, Washington, DC"},{"key":"10659_CR92","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2021.105136","volume":"127","author":"M Widbiller","year":"2021","unstructured":"Widbiller M, Rothmaier C, Saliter D, W\u00f6lflick M, Rosendahl A, Buchalla W, Schmalz G, Spruss T, Galler KM (2021) Histology of human teeth: standard and specific staining methods revisited. Arch Oral Biol 127:105136. https:\/\/doi.org\/10.1016\/j.archoralbio.2021.105136","journal-title":"Arch Oral Biol"},{"issue":"1","key":"10659_CR93","doi-asserted-by":"publisher","first-page":"438","DOI":"10.1080\/15538362.2022.2047138","volume":"22","author":"R Zhang","year":"2022","unstructured":"Zhang R, Lv J, Yu J, Xiong H, Chen P, Cao H, John Martin JJ (2022) Antioxidant analysis of different parts of several cultivars of papaya (Carica papaya L.). Int J Fruit Sci 22(1):438\u2013452","journal-title":"Int J Fruit Sci"},{"issue":"1","key":"10659_CR94","doi-asserted-by":"publisher","first-page":"36","DOI":"10.3923\/pjbs.2017.36.41","volume":"20","author":"F Zuhrotun Nisa","year":"2017","unstructured":"Zuhrotun Nisa F, Astuti M, Murdiati A, Mubarika Haryana S (2017) Anti-proliferation and apoptosis induction of aqueous leaf extract of Carica papaya L. on human breast cancer cells MCF-7. Pak J Biol Sci 20(1):36\u201341. https:\/\/doi.org\/10.3923\/pjbs.2017.36.41","journal-title":"Pak J Biol Sci"},{"key":"10659_CR95","doi-asserted-by":"crossref","unstructured":"Zuiter A (2014) Proanthocyanidin: Chemistry and biology: From phenolic compounds to proanthocyanidins.","DOI":"10.1016\/B978-0-12-409547-2.11046-7"},{"issue":"22","key":"10659_CR96","doi-asserted-by":"publisher","first-page":"2097","DOI":"10.1080\/14786419.2014.986658","volume":"29","author":"V Zunjar","year":"2015","unstructured":"Zunjar V, Mammen D, Trivedi B (2015) Antioxidant activities and phenolics profiling of different parts of Carica papaya by LCMS-MS. Nat Prod Res 29(22):2097\u20132099","journal-title":"Nat Prod Res"}],"container-title":["Journal of Molecular Histology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10735-025-10659-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10735-025-10659-1","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10735-025-10659-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T07:05:56Z","timestamp":1772003156000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10735-025-10659-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,29]]},"references-count":96,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["10659"],"URL":"https:\/\/doi.org\/10.1007\/s10735-025-10659-1","relation":{},"ISSN":["1567-2379","1567-2387"],"issn-type":[{"value":"1567-2379","type":"print"},{"value":"1567-2387","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,29]]},"assertion":[{"value":"23 April 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 November 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 December 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This study conforms to the Research Ethics Committee, National Centre for Radiation Research and Technology (NCRRT), Nasr City, Cairo, Egypt rules as well as the Institutional Research Board (IRB) and National Institutes of Health (NIH) guidelines for using animals in research. The National Centre for Radiation Research and Technology granted approval for the investigation. The committee approval number is 45A\/22. All methods were carried out in accordance with the guidelines provided by the ethics committee for the National Cent for Radiation Research and Technology in Nasr City, Cairo, Egypt, and complied with the ARRIVE guidelines.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}],"article-number":"16"}}