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Approval was granted by the Ethics Committee of Jinan Maternity Child Careand Hospital. (Date:2023\u20138-30\/NO:IRB KY-23\u201368). This study identified\u00a0ADAMTS18 as a novel tumor suppressor\u00a0in endometrial carcinoma (EC). Its downregulation can serve as a\u00a0potential diagnostic\/prognostic biomarker, correlating with advanced FIGO stage (\u2265\u2009III) and larger tumors (\u2265\u20092\u00a0cm). Critically, ADAMTS18 overexpression\u00a0suppresses the proliferation, migration, and invasion of EC cells and promotes apoptosis, establishing its\u00a0therapeutic potential\u00a0as adjuvant therapy for EC.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"The authors affirm that human research participants provided informed consent for publication of the images in Figure(s) 1\u20137 and Table(s)1\u20132.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}],"article-number":"77"}}