{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T21:45:15Z","timestamp":1792273515249,"version":"4.4.0"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Mol Histol"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1007\/s10735-026-11000-0","type":"journal-article","created":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T07:27:55Z","timestamp":1791185275000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Apigenin attenuates MASLD progression by suppressing lipogenesis and macrophage M1-like inflammatory activation: involvement of SMAD4-associated signaling"],"prefix":"10.1007","volume":"57","author":[{"given":"Lijun","family":"Cao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongna","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,10,5]]},"reference":[{"issue":"2","key":"11000_CR1","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1172\/jci22422","volume":"114","author":"JD Browning","year":"2004","unstructured":"Browning JD, Horton JD (2004) Molecular mediators of hepatic steatosis and liver injury. J Clin Invest 114(2):147\u2013152. https:\/\/doi.org\/10.1172\/jci22422","journal-title":"J Clin Invest"},{"issue":"13","key":"11000_CR2","doi-asserted-by":"publisher","first-page":"2367","DOI":"10.7150\/ijbs.47143","volume":"16","author":"J Chen","year":"2020","unstructured":"Chen J, Deng X, Liu Y, Tan Q, Huang G, Che Q, Guo J, Su Z (2020) Kupffer cells in non-alcoholic fatty liver disease: friend or foe? Int J Biol Sci 16(13):2367\u20132378. https:\/\/doi.org\/10.7150\/ijbs.47143","journal-title":"Int J Biol Sci"},{"issue":"1","key":"11000_CR3","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1002\/hep.24341","volume":"54","author":"T Csak","year":"2011","unstructured":"Csak T, Ganz M, Pespisa J, Kodys K, Dolganiuc A, Gyongyi Szabo (2011) Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells. Hepatology 54(1):133\u2013144. https:\/\/doi.org\/10.1002\/hep.24341","journal-title":"Hepatology"},{"issue":"2","key":"11000_CR4","doi-asserted-by":"publisher","first-page":"108626","DOI":"10.1016\/j.celrep.2020.108626","volume":"34","author":"S Daemen","year":"2021","unstructured":"Daemen S, Gainullina A, Kalugotla G, He L, Chan MM, Beals JW, Liss KH, Klein S, Feldstein AE, Finck BN, Artyomov MN, Schilling JD (2021) Dynamic shifts in the composition of resident and recruited macrophages influence tissue remodeling in NASH. Cell Rep 34(2):108626. https:\/\/doi.org\/10.1016\/j.celrep.2020.108626","journal-title":"Cell Rep"},{"issue":"11","key":"11000_CR5","doi-asserted-by":"publisher","first-page":"101196","DOI":"10.1016\/j.jhepr.2024.101196","volume":"6","author":"FF De Ponti","year":"2024","unstructured":"De Ponti FF, Liu Z, Scott CL (2024) Understanding the complex macrophage landscape in MASLD. JHEP Rep 6(11):101196. https:\/\/doi.org\/10.1016\/j.jhepr.2024.101196","journal-title":"JHEP Rep"},{"issue":"5","key":"11000_CR6","doi-asserted-by":"publisher","first-page":"1343","DOI":"10.1172\/jci23621","volume":"115","author":"KL Donnelly","year":"2005","unstructured":"Donnelly KL, Smith CI, Schwarzenberg SJ, Jessurun J, Boldt MD, Parks EJ (2005) Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. J Clin Invest 115(5):1343\u20131351. https:\/\/doi.org\/10.1172\/jci23621","journal-title":"J Clin Invest"},{"issue":"8","key":"11000_CR7","doi-asserted-by":"publisher","first-page":"3891","DOI":"10.1021\/acs.jcim.1c00203","volume":"61","author":"J Eberhardt","year":"2021","unstructured":"Eberhardt J, Santos-Martins D, Tillack AF, Forli S (2021) AutoDock Vina 1.2.0: new docking methods, expanded force field, and python bindings. J Chem Inf Model 61(8):3891\u20133898. https:\/\/doi.org\/10.1021\/acs.jcim.1c00203","journal-title":"J Chem Inf Model"},{"key":"11000_CR8","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1016\/j.ebiom.2016.06.017","volume":"9","author":"X Feng","year":"2016","unstructured":"Feng X, Weng D, Zhou F, Owen YD, Qin H, Zhao J, Yu W, Huang Y, Chen J, Fu H, Yang N, Chen D, Li J, Tan R, Pingping Shen (2016) Activation of PPAR\u03b3 by a natural flavonoid modulator, apigenin ameliorates obesity-related inflammation via regulation of macrophage polarization. eBioMedicine 9:61\u201376. https:\/\/doi.org\/10.1016\/j.ebiom.2016.06.017","journal-title":"eBioMedicine"},{"key":"11000_CR9","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1016\/j.bcp.2017.04.014","volume":"136","author":"X Feng","year":"2017","unstructured":"Feng X, Yu W, Li X, Zhou F, Zhang W, Shen Q, Li J, Zhang C, Shen P (2017) Apigenin, a modulator of PPAR\u03b3, attenuates HFD-induced NAFLD by regulating hepatocyte lipid metabolism and oxidative stress via Nrf2 activation. Biochem Pharmacol 136:136\u2013149. https:\/\/doi.org\/10.1016\/j.bcp.2017.04.014","journal-title":"Biochem Pharmacol"},{"issue":"7","key":"11000_CR10","doi-asserted-by":"publisher","first-page":"908","DOI":"10.1038\/s41591-018-0104-9","volume":"24","author":"SL Friedman","year":"2018","unstructured":"Friedman SL, Brent A, Neuschwander-Tetri M, Rinella, Arun J, Sanyal (2018) Mechanisms of NAFLD development and therapeutic strategies. Nat Med 24(7):908\u2013922. https:\/\/doi.org\/10.1038\/s41591-018-0104-9","journal-title":"Nat Med"},{"issue":"9","key":"11000_CR11","doi-asserted-by":"publisher","first-page":"a022061","DOI":"10.1101\/cshperspect.a022061","volume":"8","author":"A Hata","year":"2016","unstructured":"Hata A, Chen YG (2016) TGF-\u03b2 signaling from receptors to Smads. Cold Spring Harb Perspect Biol 8(9):a022061. https:\/\/doi.org\/10.1101\/cshperspect.a022061","journal-title":"Cold Spring Harb Perspect Biol"},{"issue":"10","key":"11000_CR12","doi-asserted-by":"publisher","first-page":"a022079","DOI":"10.1101\/cshperspect.a022079","volume":"8","author":"CS Hill","year":"2016","unstructured":"Hill CS (2016) Transcriptional control by the SMADs. Cold Spring Harb Perspect Biol 8(10):a022079. https:\/\/doi.org\/10.1101\/cshperspect.a022079","journal-title":"Cold Spring Harb Perspect Biol"},{"issue":"9","key":"11000_CR13","doi-asserted-by":"publisher","first-page":"1125","DOI":"10.1172\/jci15593","volume":"109","author":"JD Horton","year":"2002","unstructured":"Horton JD, Goldstein JL, Brown MS (2002) SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J Clin Invest 109(9):1125\u20131131. https:\/\/doi.org\/10.1172\/jci15593","journal-title":"J Clin Invest"},{"issue":"2","key":"11000_CR14","doi-asserted-by":"publisher","first-page":"347","DOI":"10.2337\/db09-0016","volume":"59","author":"W Huang","year":"2010","unstructured":"Huang W, Metlakunta A, Dedousis N, Zhang P, Sipula I, Dube JJ, Scott DK, O\u2019Doherty RM (2010) Depletion of liver kupffer cells prevents the development of diet-induced hepatic steatosis and insulin resistance. Diabetes 59(2):347\u2013357. https:\/\/doi.org\/10.2337\/db09-0016","journal-title":"Diabetes"},{"issue":"18","key":"11000_CR15","doi-asserted-by":"publisher","first-page":"3313","DOI":"10.1007\/s00018-018-2860-6","volume":"75","author":"D Ipsen","year":"2018","unstructured":"Ipsen D, H\u00f8jland J, Lykkesfeldt, Pernille Tveden-Nyborg (2018) Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver disease. Cell Mol Life Sci 75(18):3313\u20133327. https:\/\/doi.org\/10.1007\/s00018-018-2860-6","journal-title":"Cell Mol Life Sci"},{"issue":"9","key":"11000_CR16","doi-asserted-by":"publisher","first-page":"2100","DOI":"10.1038\/nprot.2014.138","volume":"9","author":"R Jafari","year":"2014","unstructured":"Jafari R, Almqvist H, Axelsson H, Ignatushchenko M, Lundb\u00e4ck T, Nordlund P, Martinez Molina D (2014) The cellular thermal shift assay for evaluating drug target interactions in cells. Nat Protoc 9(9):2100\u20132122. https:\/\/doi.org\/10.1038\/nprot.2014.138","journal-title":"Nat Protoc"},{"issue":"D1","key":"11000_CR17","doi-asserted-by":"publisher","first-page":"D1388","DOI":"10.1093\/nar\/gkaa971","volume":"49","author":"S Kim","year":"2021","unstructured":"Kim S, Chen J, Cheng T, Gindulyte A, He J, He S, Li Q, Shoemaker BA, Thiessen PA, Yu B, Zaslavsky L, Zhang J, Bolton EE (2021) PubChem in 2021: new data content and improved web interfaces. Nucleic Acids Res 49(D1):D1388\u2013d1395. https:\/\/doi.org\/10.1093\/nar\/gkaa971","journal-title":"Nucleic Acids Res"},{"issue":"5","key":"11000_CR18","doi-asserted-by":"publisher","first-page":"306","DOI":"10.1038\/nri.2017.11","volume":"17","author":"O Krenkel","year":"2017","unstructured":"Krenkel O, and Frank Tacke (2017) Liver macrophages in tissue homeostasis and disease. Nat Rev Immunol 17(5):306\u2013321. https:\/\/doi.org\/10.1038\/nri.2017.11","journal-title":"Nat Rev Immunol"},{"issue":"12","key":"11000_CR19","doi-asserted-by":"publisher","first-page":"3280","DOI":"10.3390\/biomedicines11123280","volume":"11","author":"N Li","year":"2023","unstructured":"Li N, Li X, Ding Y, Liu X, Diggle K, Kisseleva T, Brenner DA (2023) SREBP regulation of lipid metabolism in liver disease, and therapeutic strategies. Biomedicines 11(12):3280. https:\/\/doi.org\/10.3390\/biomedicines11123280","journal-title":"Biomedicines"},{"issue":"4","key":"11000_CR20","doi-asserted-by":"publisher","first-page":"2965","DOI":"10.3892\/etm.2019.7905","volume":"18","author":"J Lu","year":"2019","unstructured":"Lu J, Meng Z, Cheng B, Liu M, Tao S, Guan S (2019) Apigenin reduces the excessive accumulation of lipids induced by palmitic acid via the AMPK signaling pathway in HepG2 cells. Exp Ther Med 18(4):2965\u20132971. https:\/\/doi.org\/10.3892\/etm.2019.7905","journal-title":"Exp Ther Med"},{"issue":"10","key":"11000_CR21","doi-asserted-by":"publisher","first-page":"616","DOI":"10.1038\/nrm3434","volume":"13","author":"J Massagu\u00e9","year":"2012","unstructured":"Massagu\u00e9 J (2012) TGF\u03b2 signalling in context. Nat Rev Mol Cell Biol 13(10):616\u2013630. https:\/\/doi.org\/10.1038\/nrm3434","journal-title":"Nat Rev Mol Cell Biol"},{"issue":"19","key":"11000_CR22","doi-asserted-by":"publisher","first-page":"4007","DOI":"10.1016\/j.cell.2023.07.036","volume":"186","author":"J Massagu\u00e9","year":"2023","unstructured":"Massagu\u00e9 J, Sheppard D (2023) TGF-\u03b2 signaling in health and disease. Cell 186(19):4007\u20134037. https:\/\/doi.org\/10.1016\/j.cell.2023.07.036","journal-title":"Cell"},{"issue":"9","key":"11000_CR23","doi-asserted-by":"publisher","first-page":"2525","DOI":"10.1194\/jlr.M040212","volume":"54","author":"MR Maurya","year":"2013","unstructured":"Maurya MR, Gupta S, Li X, Fahy E, Dinasarapu AR, Sud M, Brown HA, Glass CK, Murphy RC, Russell DW, Dennis EA, Subramaniam S (2013) Analysis of inflammatory and lipid metabolic networks across RAW264.7 and thioglycolate-elicited macrophages. J Lipid Res 54(9):2525\u20132542. https:\/\/doi.org\/10.1194\/jlr.M040212","journal-title":"J Lipid Res"},{"issue":"18","key":"11000_CR24","doi-asserted-by":"publisher","first-page":"7032","DOI":"10.1021\/acs.jafc.2c07581","volume":"71","author":"Z Meng","year":"2023","unstructured":"Meng Z, Gao M, Wang C, Guan S, Zhang D, Lu J (2023) Apigenin alleviated high-fat-diet-induced hepatic pyroptosis by mitophagy-ROS-CTSB-NLRP3 pathway in mice and AML12 Cells. J Agric Food Chem 71(18):7032\u20137045. https:\/\/doi.org\/10.1021\/acs.jafc.2c07581","journal-title":"J Agric Food Chem"},{"issue":"1","key":"11000_CR25","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1016\/j.immuni.2014.06.008","volume":"41","author":"PJ Murray","year":"2014","unstructured":"Murray PJ, Allen JE, Biswas SK, Fisher EA, Gilroy DW, Goerdt S, Gordon S, Hamilton JA, Ivashkiv LB, Lawrence T, Locati M, Mantovani A, Martinez FO, Mege JL, Mosser DM, Natoli G, Saeij JP, Schultze JL, Shirey KA, Sica A, Suttles J, Udalova I, van Ginderachter JA, Vogel SN, Wynn TA (2014) Macrophage activation and polarization: nomenclature and experimental guidelines. Immunity 41(1):14\u201320. https:\/\/doi.org\/10.1016\/j.immuni.2014.06.008","journal-title":"Immunity"},{"issue":"12","key":"11000_CR26","doi-asserted-by":"publisher","first-page":"1493","DOI":"10.1016\/S0969-2126(00)88340-9","volume":"7","author":"B Qin","year":"1999","unstructured":"Qin B, Lam SSW, Kai Lin (1999) Crystal structure of a transcriptionally active Smad4 fragment. Structure 7(12):1493\u20131503. https:\/\/doi.org\/10.1016\/S0969-2126(00)88340-9","journal-title":"Structure"},{"issue":"5","key":"11000_CR27","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1111\/1751-2980.12599","volume":"19","author":"G Qin","year":"2018","unstructured":"Qin G, Wang GZ, Guo DD, Bai RX, Wang M, Du SY (2018) Deletion of Smad4 reduces hepatic inflammation and fibrogenesis during nonalcoholic steatohepatitis progression. J Dig Dis 19(5):301\u2013313. https:\/\/doi.org\/10.1111\/1751-2980.12599","journal-title":"J Dig Dis"},{"issue":"6","key":"11000_CR28","doi-asserted-by":"publisher","first-page":"1966","DOI":"10.1097\/hep.0000000000000520","volume":"78","author":"ME Rinella","year":"2023","unstructured":"Rinella ME, Lazarus JV, Ratziu V, Francque SM, Sanyal AJ, Kanwal F, Romero D, Abdelmalek MF, Anstee QM, Arab JP, Arrese M, Bataller R, Beuers U, Boursier J, Bugianesi E, Byrne CD, Castro Narro GE, Chowdhury A, Cortez-Pinto H, Cryer DR, Cusi K, El-Kassas M, Klein S, Eskridge W, Fan J, Gawrieh S, Guy CD, Harrison SA, Kim SU, Koot BG, Korenjak M, Kowdley KV, Lacaille F, Loomba R, Mitchell-Thain R, Morgan TR, Powell EE, Roden M, Romero-G\u00f3mez M, Silva M, Singh SP, Sookoian SC, Spearman CW, Tiniakos D, Valenti L, Vos MB, Wong VW, Xanthakos S, Yilmaz Y, Younossi Z, Hobbs A, Villota-Rivas M, Newsome PN (2023). A multisociety Delphi consensus statement on new fatty liver disease nomenclature. Hepatology 78 (6):1966\u20131986. https:\/\/doi.org\/10.1097\/hep.0000000000000520","journal-title":"Hepatology"},{"issue":"6","key":"11000_CR29","doi-asserted-by":"publisher","first-page":"1305","DOI":"10.3390\/ijms20061305","volume":"20","author":"B Salehi","year":"2019","unstructured":"Salehi B, Venditti A, Sharifi-Rad M, Kr\u0119giel D, Sharifi-Rad J, Durazzo A, Lucarini M, Santini A, Souto EB Novellino E, Antolak H, Azzini E, Setzer WN, Martins N (2019) Therapeutic potential apigenin. Int J Mol Sci 20(6):1305. https:\/\/doi.org\/10.3390\/ijms20061305","journal-title":"Int J Mol Sci"},{"issue":"12","key":"11000_CR30","doi-asserted-by":"publisher","first-page":"1596","DOI":"10.1038\/s42255-021-00501-9","volume":"3","author":"H Tilg","year":"2021","unstructured":"Tilg H, Adolph TE, Dudek M, Knolle P (2021) Non-alcoholic fatty liver disease: the interplay between metabolism, microbes and immunity. Nat Metabolism 3(12):1596\u20131607. https:\/\/doi.org\/10.1038\/s42255-021-00501-9","journal-title":"Nat Metabolism"},{"issue":"11","key":"11000_CR31","doi-asserted-by":"publisher","first-page":"678","DOI":"10.1038\/nrm4074","volume":"16","author":"Y Wang","year":"2015","unstructured":"Wang Y, Viscarra J, Kim SJ, Sul HS (2015) Transcriptional regulation of hepatic lipogenesis. Nat Rev Mol Cell Biol 16(11):678\u2013689. https:\/\/doi.org\/10.1038\/nrm4074","journal-title":"Nat Rev Mol Cell Biol"},{"issue":"1","key":"11000_CR32","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1124\/jpet.120.000162","volume":"377","author":"L Wu","year":"2021","unstructured":"Wu L, Guo T, Deng R, Liu L, and Yongxiong Yu (2021) Apigenin ameliorates insulin resistance and lipid accumulation by endoplasmic reticulum stress and SREBP-1c\/SREBP-2 pathway in palmitate-induced HepG2 cells and high-fat diet\u2013fed mice. J Pharmacol Exp Ther 377(1):146\u2013156. https:\/\/doi.org\/10.1124\/jpet.120.000162","journal-title":"J Pharmacol Exp Ther"},{"issue":"1","key":"11000_CR33","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1038\/s41419-025-07376-8","volume":"16","author":"W Yang","year":"2025","unstructured":"Yang W, Yan X, Chen R, Xin X, Ge S, Zhao Y, Yan X, Zhang J (2025) Smad4 deficiency in hepatocytes attenuates NAFLD progression via inhibition of lipogenesis and macrophage polarization. Cell Death Dis 16(1):58. https:\/\/doi.org\/10.1038\/s41419-025-07376-8","journal-title":"Cell Death Dis"},{"key":"11000_CR34","doi-asserted-by":"publisher","first-page":"1679919","DOI":"10.3389\/fphar.2025.1679919","volume":"16","author":"H Yoon","year":"2025","unstructured":"Yoon H, Gong YL, Seo J, Kim J, Uddin MS, Han SB, Sayeon Cho (2025) Anti-inflammatory and antioxidant effects of Pogostemon stellatus (Lour.) Kuntze via MAPK, NF-\u03baB, and Nrf2 signaling pathways in LPS-activated RAW 264.7 macrophages. Front Pharmacol 16:1679919. https:\/\/doi.org\/10.3389\/fphar.2025.1679919","journal-title":"Front Pharmacol"},{"issue":"4","key":"11000_CR35","doi-asserted-by":"publisher","first-page":"1335","DOI":"10.1097\/hep.0000000000000004","volume":"77","author":"ZM Younossi","year":"2023","unstructured":"Younossi ZM, Golabi P, Paik JM, Henry A, Van Dongen C, Henry L (2023) The global epidemiology of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH): a systematic review. Hepatology 77(4):1335\u20131347. https:\/\/doi.org\/10.1097\/hep.0000000000000004","journal-title":"Hepatology"},{"issue":"1","key":"11000_CR37","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1476-511X-11-1","volume":"11","author":"Y Zhang","year":"2012","unstructured":"Zhang Y, Xue R, Zhang Z, Yang X, Hongyang, Shi (2012) Palmitic and linoleic acids induce ER stress and apoptosis in hepatoma cells. Lipids Health Dis 11(1):1. https:\/\/doi.org\/10.1186\/1476-511X-11-1","journal-title":"Lipids Health Dis"},{"issue":"9","key":"11000_CR36","doi-asserted-by":"publisher","first-page":"e107072","DOI":"10.1371\/journal.pone.0107072","volume":"9","author":"X Zhang","year":"2014","unstructured":"Zhang X, Wang G, Gurley EC, Zhou H (2014) Flavonoid apigenin inhibits lipopolysaccharide-induced inflammatory response through multiple mechanisms in macrophages. PLoS ONE 9(9):e107072. https:\/\/doi.org\/10.1371\/journal.pone.0107072","journal-title":"PLoS ONE"}],"container-title":["Journal of Molecular Histology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10735-026-11000-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10735-026-11000-0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10735-026-11000-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T21:19:44Z","timestamp":1792271984000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10735-026-11000-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":37,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["11000"],"URL":"https:\/\/doi.org\/10.1007\/s10735-026-11000-0","relation":{},"ISSN":["1567-2379","1567-2387"],"issn-type":[{"value":"1567-2379","type":"print"},{"value":"1567-2387","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"3 July 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 September 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 October 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"328"}}