{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T16:26:32Z","timestamp":1773419192391,"version":"3.50.1"},"reference-count":69,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Heart Fail Rev"],"published-print":{"date-parts":[[2005,1]]},"DOI":"10.1007\/s10741-005-2347-z","type":"journal-article","created":{"date-parts":[[2005,6,9]],"date-time":"2005-06-09T17:35:03Z","timestamp":1118338503000},"page":"39-46","source":"Crossref","is-referenced-by-count":16,"title":["Effects of Aldosterone and Mineralocorticoid Receptor Blockade on Intracellular Electrolytes"],"prefix":"10.1007","volume":"10","author":[{"given":"Martin","family":"Wehling","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"2347_CR1","doi-asserted-by":"crossref","first-page":"2103","DOI":"10.1172\/JCI104436","volume":"40","author":"J Crabbe","year":"1961","unstructured":"Crabbe J. Stimulation of active sodium transport by the isolated toad bladder with aldosterone in vitro. J Clin Invest 1961;40:2103\u20132110.","journal-title":"J Clin Invest"},{"key":"2347_CR2","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1073\/pnas.50.6.1169","volume":"50","author":"IS Edelman","year":"1963","unstructured":"Edelman IS, Bogoroch R, Porter GA. On the mechanism of action of aldosterone on sodium transport: The role of protein synthesis. Proc Natl Acad Sci USA 1963;50:1169\u20131177.","journal-title":"Proc Natl Acad Sci USA"},{"key":"2347_CR3","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1126\/science.3037703","volume":"23","author":"LA Arriza","year":"1987","unstructured":"Arriza LA, Weinberger C, Cerelli G, Glaser TM, Handelin BL, et al. Cloning of human mineralocorticoid receptor complementary DNA: Structural and functional kinship with the glucocorticoid receptor. Science 1987;23:268\u2013275.","journal-title":"Science"},{"key":"2347_CR4","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1038\/367463a0","volume":"367","author":"CM Canessa","year":"1994","unstructured":"Canessa CM, Schild L, Buell G, Thorens B, Gautschi I, Horisberger J-D, Rossier BC. Amiloride-sensitive epithelial Na_ channel is made of three homologous subunits. Nature 1994;367:463\u2013467.","journal-title":"Nature"},{"key":"2347_CR5","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1038\/ki.1995.376","volume":"48","author":"CM Canessa","year":"1995","unstructured":"Canessa CM, Horisberger J-D Schild L, Rossier BC. Expression cloning of the epithelial sodium channel. Kidney Int 1995;48:950\u2013955.","journal-title":"Kidney Int"},{"key":"2347_CR6","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/0092-8674(94)90250-X","volume":"79","author":"RA Shimkets","year":"1994","unstructured":"Shimkets RA, Warnock DG, Bositis CM, Nelson-Williams C, Hansson JH, Schambelan M, Gill JR, Ulick S, Milora RV, Findling JW, Canessa CM, Rossier BC, Lifton RP. Liddle\u2019s syndrome: Heritable human hypertension caused by mutations in the alpha-subunit of the epithelial sodium channel. Cell 1994;79:407\u2013414.","journal-title":"Cell"},{"key":"2347_CR7","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1038\/355262a0","volume":"355","author":"RP Lifton","year":"1992","unstructured":"Lifton RP, Dluhy RG, Powers M, Rich GM, Cook S, Ulick S, Lalouel J. A chimaeric 11-beta-hydroxylase\/aldosterone synthase gene causes glucocorticoid-remediable aldosteronism and human hypertension. Nature 1992;355:262\u2013265.","journal-title":"Nature"},{"key":"2347_CR8","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1038\/ng0895-394","volume":"10","author":"T Mune","year":"1995","unstructured":"Mune T, Rogerson FM, Nikkila H, Agarwal AK, White PC. Human hypertension caused by mutations in the kidney isozyme of 11-beta-hydroxysteroid dehydrogenase. Nat Genet 1995;10:394\u2013399.","journal-title":"Nat Genet"},{"key":"2347_CR9","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1126\/science.289.5476.119","volume":"289","author":"DS Geller","year":"2000","unstructured":"Geller DS, Farhi A, Pinkerton N, Fradley M, Moritz M, Spitzer A, Meinke G, Tsai FTF, Sigler PB, Lifton RP. Activating mineralocorticoid receptor mutation in hypertension exacerbated by pregnancy. Science 2000;289:119\u2013123.","journal-title":"Science"},{"key":"2347_CR10","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1146\/annurev.physiol.59.1.365","volume":"59","author":"M Wehling","year":"1997","unstructured":"Wehling M. Specific, nongenomic actions of steroid hormones. Annu Rev Physiol 1997;59:365\u2013393.","journal-title":"Annu Rev Physiol"},{"key":"2347_CR11","doi-asserted-by":"crossref","first-page":"F319","DOI":"10.1152\/ajprenal.1999.277.3.F319","volume":"277","author":"F Verrey","year":"1999","unstructured":"Verrey F. Early aldosterone action: Toward filling the gap between transcription and transport. Am J Physiol (Renal Physiol) 1999;277:F319\u2013F327.","journal-title":"Am J Physiol (Renal Physiol)"},{"key":"2347_CR12","doi-asserted-by":"crossref","first-page":"013","DOI":"10.1159\/000070245","volume":"13","author":"D Pearce","year":"2003","unstructured":"Pearce D. SGK1 Regulation of Epithelial Sodium Transport. Cell Physiol Biochem 2003;13:013\u2013020.","journal-title":"Cell Physiol Biochem"},{"key":"2347_CR13","doi-asserted-by":"crossref","first-page":"2514","DOI":"10.1073\/pnas.96.5.2514","volume":"96","author":"S-Y Chen","year":"1999","unstructured":"Chen S-Y, Bhargava A, Mastroberardino L, Meijer OC, Wang J, Buse P, Firestone GL, Verrey F, Pearce D. Epithelial sodium channel regulated by aldosterone-induced protein SGK. Proc Natl Acad Sci USA 1999;96:2514\u20132519.","journal-title":"Proc Natl Acad Sci USA"},{"key":"2347_CR14","doi-asserted-by":"crossref","first-page":"7052","DOI":"10.1093\/emboj\/20.24.7052","volume":"20","author":"C Debonneville","year":"2001","unstructured":"Debonneville C, Flores SY, Kamynina E, Plant PJ, Tauxe C, Thomas MA, Munster C, Chraibi A, Pratt JH, Horisberger JD, Pearce D, Loffing J, Staub O. Phosphorylation of Nedd4\u20132 by SGK1 regulates epithelial Na(+) channel cell surface expression. Embo J 2001;20:7052\u20137059.","journal-title":"Embo J"},{"key":"2347_CR15","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1085\/jgp.102.1.25","volume":"102","author":"J Pa\u2032cha","year":"1993","unstructured":"Pa\u2032cha J, Frindt G, Antonian L, Silver RB, Palmer LG. Regulation of Na channels of the rat cortical collecting tubule by aldosterone. J Gen Physiol 1993;102:25\u201342.","journal-title":"J Gen Physiol"},{"key":"2347_CR16","doi-asserted-by":"crossref","first-page":"C605","DOI":"10.1152\/ajpcell.1996.271.2.C605","volume":"271","author":"C Asher","year":"1996","unstructured":"Asher C, Wald H, Rossier BC, Garty H. Aldosterone-induced increase in the abundance of Na-channel subunits. Am J Physiol Cell Physiol 1996;271:C605\u2013C611.","journal-title":"Am J Physiol Cell Physiol"},{"key":"2347_CR17","doi-asserted-by":"crossref","first-page":"C1699","DOI":"10.1152\/ajpcell.1998.274.6.C1699","volume":"274","author":"JB Stokes","year":"1998","unstructured":"Stokes JB, Sigmund RD. Regulation of rENaC mRNA by dietary NaCl and steroids: Organ, tissue, and steroid heterogeneity. Am J Physiol Cell Physiol 1998;274:C1699\u2013C1707.","journal-title":"Am J Physiol Cell Physiol"},{"key":"2347_CR18","doi-asserted-by":"crossref","first-page":"323","DOI":"10.3181\/00379727-99-24338","volume":"99","author":"AJ Vander","year":"1958","unstructured":"Vander AJ, Malvin RL, Wilde WS, Lapides J, Sullivan LP, McMurray VM. Effects of adrenalectomy and aldosterone on proximal and distal tubular sodium reabsorption. Proc Soc Exp Biol Med 1958;99:323\u2013325.","journal-title":"Proc Soc Exp Biol Med"},{"key":"2347_CR19","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1126\/science.3037703","volume":"23","author":"LA Arriza","year":"1987","unstructured":"Arriza LA, Weinberger C, Cerelli G, Glaser TM, Handelin BL, et al. Cloning of human mineralocorticoid receptor complementary DNA: Structural and functional kinship with the glucocorticoid receptor. Science 1987;23:268\u2013275.","journal-title":"Science"},{"key":"2347_CR20","first-page":"1","volume":"24","author":"IS Edelman","year":"1968","unstructured":"Edelman IS, Fimognari GM. Modes of hormone action: On the biochemical mechanism of action of aldosterone. Recent Prog Hormone Res 1968;24:1\u201344.","journal-title":"Recent Prog Hormone Res"},{"key":"2347_CR21","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1126\/science.8382375","volume":"259","author":"JW Funder","year":"1993","unstructured":"Funder JW. Mineralocorticoids, glucocorticoids, receptors and response elements. Science 1993;259:1132\u20131136.","journal-title":"Science"},{"key":"2347_CR22","first-page":"131","volume-title":"Endocrinology of Hypertension","author":"JH Myers","year":"1985","unstructured":"Myers JH, Bohr D. Mechanisms responsible for the pressure elevation in sodium dependent mineralocorticoid hypertension. In: Mantero F, Biglieri EG, Edwards CRW, eds., Endocrinology of Hypertension, New York: Raven, 1985:131\u2013148."},{"key":"2347_CR23","first-page":"1373","volume-title":"The Kidney: Physiology and Pathophysiology","author":"BC Rossier","year":"1992","unstructured":"Rossier BC, Palmer LG. Mechanisms of aldosteroneaction on sodium and potassium transport. In: Seldin DW, Giebisch G, eds., The Kidney: Physiology and Pathophysiology, 2nd ed. New York: Raven Press, 1992;1373\u20131409.","edition":"2"},{"key":"2347_CR24","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/BF00232796","volume":"144","author":"F Verrey","year":"1995","unstructured":"Verrey F. Transcriptional control of sodium transport in tight epithelia by adrenal steroids. J Membr Biol 1995;144:93\u2013110.","journal-title":"J Membr Biol"},{"key":"2347_CR25","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1210\/endo.135.3.8070376","volume":"135","author":"M Lombes","year":"1994","unstructured":"Lombes M, Kenouch S, Souque A, Farman N, Rafestin-Oblin ME. The mineralocorticoid receptor discriminates aldosterone from glucocorticoids independently of the 11 beta-hydroxysteroid dehydrogenase. Endocrinology 1994:135, 834\u2013840.","journal-title":"Endocrinology"},{"key":"2347_CR26","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1152\/physrev.1997.77.2.359","volume":"77","author":"H Garty","year":"1997","unstructured":"Garty H, Palmer LG. Epithelial sodium channels: Function, structure, and regulation. Physiol Rev 1997;77:359\u2013396.","journal-title":"Physiol Rev"},{"key":"2347_CR27","doi-asserted-by":"crossref","first-page":"C825","DOI":"10.1152\/ajpcell.1992.263.4.C825","volume":"263","author":"AE Kemendy","year":"1992","unstructured":"Kemendy AE, Kleyman TR, Eaton DC. Aldosterone alters the open probability of amiloride-blockable sodium channels in A6 epithelia. Am J Physiol 1992;263:C825\u2013 C837.","journal-title":"Am J Physiol"},{"key":"2347_CR28","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1007\/BF00663910","volume":"339","author":"G El Mernissi","year":"1983","unstructured":"El Mernissi G, Doucet A. Short-term effect of aldosterone on renal sodium transport and tubular Na-K-ATPase in the rat. Pfl\u00fcgers Arch 1983;339:139\u2013146.","journal-title":"Pfl\u00fcgers Arch"},{"key":"2347_CR29","first-page":"279","volume":"22","author":"F Verrey","year":"1996","unstructured":"Verrey F, Beron J, Spindler B. Corticosteroid regulation of renal Na,K-ATPase. Miner Electrolyte Metab 1996;22:279\u2013292.","journal-title":"Miner Electrolyte Metab"},{"key":"2347_CR30","doi-asserted-by":"crossref","first-page":"E505","DOI":"10.1152\/ajpcell.1987.252.5.C505","volume":"252","author":"M Wehling","year":"1987","unstructured":"Wehling M, Armanini D, Strasser T, Weber PC. Effect of aldosterone on the sodium and potassium concentrations in human mononuclear leukocytes. Am J Physiol 1987;252:E505\u2013E508.","journal-title":"Am J Physiol"},{"key":"2347_CR31","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/0143-4160(90)90010-R","volume":"11","author":"M Wehling","year":"1990","unstructured":"Wehling M, K\u00e4smayr J, Theisen K. Aldosterone influences free intracellular calcium in human mononuclear leukocytes in vitro. Cell Calcium 1990;11:565\u2013571.","journal-title":"Cell Calcium"},{"key":"2347_CR32","first-page":"E170","volume":"257","author":"M Wehling","year":"1989","unstructured":"Wehling M, Kuhls S, Armanini D. Volume regulation of human lymphocytes by aldosterone in isotonic medium. Am J Physiol 1989;257:E170\u2013E174.","journal-title":"Am J Physiol"},{"key":"2347_CR33","first-page":"E719","volume":"260","author":"M Wehling","year":"1991","unstructured":"Wehling M, K\u00e4smayr J, Theisen K. Rapid effects of mineralocorticoids on sodium-proton exchanger: Genomic or nongenomic pathway? Am J Physiol 1991;260:E719\u2013E726.","journal-title":"Am J Physiol"},{"key":"2347_CR34","first-page":"1452","volume":"77","author":"M Christ","year":"1993","unstructured":"Christ M, Eisen C, Aktas J, Theisen K, Wehling M. The inositol-1,4,5-trisphosphate system is involved in rapid effects of aldosterone in human mononuclear leukocytes. J Clin Endocrinol Metab 1993;77:1452\u20131457.","journal-title":"J Clin Endocrinol Metab"},{"key":"2347_CR35","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1161\/01.HYP.25.1.117","volume":"25","author":"M Christ","year":"1995","unstructured":"Christ M, Douwes K, Eisen C, Bechtner G, Theisen K, Wehling M. Rapid effects of aldosterone on sodium transport in vascular smooth muscle cells. Hypertension 1995;25:117\u2013123.","journal-title":"Hypertension"},{"key":"2347_CR36","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1073\/pnas.84.5.1464","volume":"84","author":"H Oberleithner","year":"1987","unstructured":"Oberleithner H, Weigt M, Westphale HJ, Wang W. Aldosterone activates Na+\/H+ exchange and raises cytoplasmic pH in target cells of the amphibian kidney. Proc Natl Acad Sci USA 1987;84:1464\u20131468.","journal-title":"Proc Natl Acad Sci USA"},{"key":"2347_CR37","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1016\/0006-291X(92)90233-B","volume":"189","author":"M Wehling","year":"1992","unstructured":"Wehling M, Eisen C, Aktas J, Christ M, Theisen K. Photoaffinity labeling of plasma membrane receptors for aldosterone from human mononuclear leukocytes. Biochem Biophys Res Commun 1992;189:1424\u20131428.","journal-title":"Biochem Biophys Res Commun"},{"key":"2347_CR38","first-page":"E974","volume":"263","author":"M Wehling","year":"1992","unstructured":"Wehling M, Christ M, Theisen K. Membrane receptors for aldosterone: A novel pathway for mineralocorticoid action. Am J Physiol 1992;263:E974\u2013E979.","journal-title":"Am J Physiol"},{"key":"2347_CR39","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1152\/physrev.00003.2003","volume":"83","author":"RM L\u00f6sel","year":"2003","unstructured":"L\u00f6sel RM, Falkenstein E, Feuring M, Schultz A, Tillmann HC, Rossol-Haseroth K, Wehling M. Nongenomic Steroid Action: Controversies, Questions, and Answers. Physiol Rev 2003;83:965\u20131016.","journal-title":"Physiol Rev"},{"key":"2347_CR40","doi-asserted-by":"crossref","first-page":"2231","DOI":"10.1073\/pnas.0336132100","volume":"100","author":"Y Zhu","year":"2003","unstructured":"Zhu Y, Rice CD, Pang Y, Pace M, Thomas P. Cloning, expression, and characterization of a membrane progestin receptor and evidence it is an intermediary in meiotic maturation of fish oocytes. Proc Natl Acad Sci USA 2003;100:2231\u20132236.","journal-title":"Proc Natl Acad Sci USA"},{"key":"2347_CR41","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1172\/JCI104906","volume":"43","author":"C Spach","year":"1964","unstructured":"Spach C, Streeten DH. Retardation of sodium exchange in dog erythrocytes by physiological concentrations of aldosterone, in vitro. J Clin Invest 1964;43:217\u2013227.","journal-title":"in vitro. J Clin Invest"},{"key":"2347_CR42","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1161\/01.HYP.6.3.425","volume":"6","author":"AM Moura","year":"1984","unstructured":"Moura AM, Worcel M. Direct action of aldosterone on transmembrane NaC efflux from arterial smooth muscle. Hypertension 1984;6:425\u2013430.","journal-title":"Hypertension"},{"key":"2347_CR43","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1172\/JCI115555","volume":"89","author":"D Petzel","year":"1992","unstructured":"Petzel D, Ganz MB, Nestler EJ, Lewis JJ, Goldenring J, et al. Correlates of aldosterone-induced increases in Ca2C I and Isc suggest that Ca2C i is the second messenger for stimulation of apical membrane conductance. J Clin Invest 1992;89:150\u2013156.","journal-title":"J Clin Invest"},{"key":"2347_CR44","first-page":"E487","volume":"261","author":"A Menachery","year":"1991","unstructured":"Menachery A, Braley LM, Kifor I, Gleason R,Williams GH. Dissociation in plasma renin and adrenal ANG II and aldosterone responses to sodium restriction in rats. Am J Physiol 1991;261:E487\u2013E449.","journal-title":"Am J Physiol"},{"key":"2347_CR45","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1210\/jcem-46-1-105","volume":"46","author":"EAS Al-Dujaili","year":"1978","unstructured":"Al-Dujaili EAS, Edwards CRW. The development and application of direct radioimmunoassay for plasma aldosterone using 131I-labelled ligandcomparison of three methods. J Clin Endocrinol Metab 1978; 46:105\u2013113.","journal-title":"J Clin Endocrinol Metab"},{"key":"2347_CR46","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1161\/01.HYP.35.5.1099","volume":"35","author":"R Alzamora","year":"2000","unstructured":"Alzamora R, Michea L, Marusic ET. Role of 11beta-hydroxysteroid dehydrogenase in non-genomic aldosterone effects in human arteries. Hypertension 2000;35,1099\u20131104.","journal-title":"Hypertension"},{"key":"2347_CR47","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1161\/01.RES.76.6.973","volume":"76","author":"M Wehling","year":"1995","unstructured":"Wehling M, Neylon CB, Fullerton M, Bobik A, Funder JW. Nongenomic effects of aldosterone on intracellular calcium in vascular smooth muscle cells. Circ Res 1995;76:973\u2013 979.","journal-title":"Circ Res"},{"key":"2347_CR48","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1006\/bbrc.1994.2484","volume":"204","author":"M Wehling","year":"1994","unstructured":"Wehling M, Ulsenheimer A, Schneider M, Neylon C, Christ M. Rapid effects of aldosterone on free intracellular calcium in vascular smooth muscle and endothelial cells: Subcellular localization of calcium release by single cell imaging. Biochem Biophys Res Commun 1994;204:475\u2013 481.","journal-title":"Biochem Biophys Res Commun"},{"key":"2347_CR49","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1006\/bbrc.1995.2106","volume":"213","author":"M Christ","year":"1995","unstructured":"Christ M, Eisen C, Meyer C, Theisen K, Wehling M. Immediate effects of aldosterone on diacylglycerol production and protein kinaseCtranslocation in vascular smooth muscle cells. Biochem Biophys Res Commun 1995;213:123\u2013129.","journal-title":"Biochem Biophys Res Commun"},{"key":"2347_CR50","first-page":"R564","volume":"266","author":"SN Thornton","year":"1994","unstructured":"Thornton SN, Nicolaidis S. Long-term mineralocorticoid-induced changes in rat neuron properties plus interaction of aldosterone and ANG II. Am J Physiol 1994;266:R564\u2013R571.","journal-title":"Am J Physiol"},{"key":"2347_CR51","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1046\/j.1523-1755.1999.00674.x","volume":"56","author":"S Ebata","year":"1999","unstructured":"Ebata S, Muto S, Okada K, Nemoto J, Amemiya M, Saito T, Asano Y. Aldosterone activates Na1\/H1 exchange in vascular smooth muscle cells by nongenomic and genomic mechanisms. Kidney Int 1999;56:1400\u20131412.","journal-title":"Kidney Int"},{"key":"2347_CR52","doi-asserted-by":"crossref","first-page":"C1673","DOI":"10.1152\/ajpcell.1997.273.5.C1673","volume":"273","author":"M Gekle","year":"1997","unstructured":"Gekle M, Silbernagl S, Oberleithner H. The mineralocorticoid aldosterone activates a proton conductance in cultured kidney cells. Am J Physiol 1997;273:C1673\u2013C1678.","journal-title":"Am J Physiol"},{"key":"2347_CR53","doi-asserted-by":"crossref","first-page":"3410","DOI":"10.1210\/endo.138.8.5352","volume":"138","author":"A Sato","year":"1997","unstructured":"Sato A, Liu JP, Funder JW. Aldosterone rapidly represses protein kinase C activity in neonatal rat cardiomyocytes in vitro. Endocrinology 1997;138:3410\u20133416.","journal-title":"Endocrinology"},{"key":"2347_CR54","doi-asserted-by":"crossref","first-page":"8763","DOI":"10.1074\/jbc.271.15.8763","volume":"271","author":"CM Doolan","year":"1996","unstructured":"Doolan CM, Harvey BJ. Modulation of cytosolic protein kinase C and calcium ion activity by steroid hormones in rat distal colon. J Biol Chem 1996;271:8763\u20138767.","journal-title":"J Biol Chem"},{"key":"2347_CR55","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1161\/01.RES.85.12.1139","volume":"85","author":"JP Benitah","year":"1999","unstructured":"Benitah JP, Vassort G. Aldosterone upregulates Ca(21) current in adult rat cardiomyocytes. Circ Res 1999;85:1139\u20131145.","journal-title":"Circ Res"},{"key":"2347_CR56","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/253357a0","volume":"253","author":"RJ Pietras","year":"1975","unstructured":"Pietras RJ, Szego CM. Endometrial cell calcium and oestrogen action. Nature (Lond) 1975; 253:357\u2013359.","journal-title":"Nature (Lond)"},{"key":"2347_CR57","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1038\/265069a0","volume":"265","author":"RJ Pietras","year":"1977","unstructured":"Pietras RJ, Szego CM. Specific binding sites for oestrogen at the outer surfaces of isolated endometrial cells. Nature (Lond) 1977;265:69\u201372.","journal-title":"Nature (Lond)"},{"key":"2347_CR58","doi-asserted-by":"crossref","unstructured":"Pietras RJ, Szego CM. Cell membrane estrogen receptors on the surface. Nat Med 5:1330.","DOI":"10.1038\/70877"},{"key":"2347_CR59","unstructured":"= 10."},{"key":"2347_CR60","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1210\/endo.134.4.8137736","volume":"134","author":"SK Nordeen","year":"1994","unstructured":"Nordeen SK, Moyer ML, Bona BJ. The coupling of multiple signal transduction pathways with steroid response mechanisms. Endocrinology 1994;134:1723\u20131732.","journal-title":"Endocrinology"},{"key":"2347_CR61","doi-asserted-by":"crossref","first-page":"2537","DOI":"10.1210\/endo.138.6.5214","volume":"138","author":"SS Lim-Tio","year":"1997","unstructured":"Lim-Tio SS, Keightley M-C, Fuller PJ. Determinants of specificity of transactivation by the mineralocorticoid or glucocorticoid receptor. Endocrinology 1997;138: 2537\u20132543.","journal-title":"Endocrinology"},{"key":"2347_CR62","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1006\/bbrc.1999.1771","volume":"266","author":"K Haseroth","year":"1999","unstructured":"Haseroth K, Gerdes D, Berger S, Feuring M, Gunther A, Herbst C, Christ M, Wehling M. Rapid nongenomic effects of aldosterone in mineralocorticoidreceptor-knockout mice. Biochem Biophys Res Commun 1999;266:257\u2013261.","journal-title":"Biochem Biophys Res Commun"},{"key":"2347_CR63","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.bbrc.2004.04.026","volume":"318","author":"K Rossol-Haseroth","year":"2004","unstructured":"Rossol-Haseroth K, Zhou Q, Braun S, Boldyreff B, Falkenstein E, Wehling M. Mineralocorticoid receptor antagonists do not block rapid ERK activation by aldosterone. Biochem Biophys Res Commun 2004;318:281\u2013288.","journal-title":"Biochem Biophys Res Commun"},{"key":"2347_CR64","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1210\/en.2003-1137","volume":"145","author":"AS Mihailidou","year":"2004","unstructured":"Mihailidou AS, Mardini M, Funder JW. Rapid, nongenomic effects of aldosterone in the heart mediated by epsilon protein kinase C. Endocrinology 2004;145:773\u2013780.","journal-title":"Endocrinology"},{"key":"2347_CR65","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1161\/01.RES.0000106135.02935.E1","volume":"93","author":"TR Uhrenholt","year":"2003","unstructured":"Uhrenholt TR, Schjerning J, Hansen PB, Norregaard R, Jensen BL, Sorensen GL, Skott O. Rapid inhibition of vasoconstriction in renal afferent arterioles by aldosterone. Circ Res 2003;93:1258\u20131266.","journal-title":"Circ Res"},{"key":"2347_CR66","first-page":"1145","volume":"15","author":"C Moellic","year":"2004","unstructured":"Moellic C, Ouvrard-Pascaud A, Capurro C, Cluzeaud F, Fay M, Jaisser F, Farman N, Blot-Chabaud M. Early Nongenomic Events in Aldosterone Action in Renal Collecting Duct Cells: PKC Activation, Mineralocorticoid Receptor Phosphorylation, and Cross-Talk with the Genomic Response. J Am Soc Nephrol 2004;15:1145\u20131160.","journal-title":"J Am Soc Nephrol"},{"key":"2347_CR67","doi-asserted-by":"crossref","unstructured":"L\u00f6sel R, Schultz A, Boldyreff B, Wehling M, Rapid effects of aldosterone on vascular cells: Clinical implications. In: Norman AW, Wehling M, Baldi E, Forti G, es., Special issue: Proceedings of the Third International Meeting on Rapid Responses to Steroid Hormones. Steroids 2004;69;575\u2013 578.","DOI":"10.1016\/j.steroids.2004.05.005"},{"key":"2347_CR68","first-page":"761","volume":"86","author":"B.MW Schmidt","year":"2001","unstructured":"Schmidt B.MW, Georgens AC, Martin N, Tillmann HC, Feuring M, Christ M, Wehling M. Interaction of rapid nongenomic cardiovascular aldosterone effects with the adrenergic system. J Clin Endocrinol Metab 2001;86,761\u2013767.","journal-title":"J Clin Endocrinol Metab"},{"key":"2347_CR69","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1172\/JCI118867","volume":"98","author":"EL Greene","year":"1996","unstructured":"Greene EL, Kren S, Hostetter TH. Role of aldosterone in the remnant kidney model in the rat. J Clin Invest 1996;98:1063\u20131068.","journal-title":"J Clin Invest"}],"container-title":["Heart Failure Reviews"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10741-005-2347-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10741-005-2347-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10741-005-2347-z","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,7]],"date-time":"2020-04-07T15:53:38Z","timestamp":1586274818000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10741-005-2347-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,1]]},"references-count":69,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2005,1]]}},"alternative-id":["2347"],"URL":"https:\/\/doi.org\/10.1007\/s10741-005-2347-z","relation":{},"ISSN":["1382-4147","1573-7322"],"issn-type":[{"value":"1382-4147","type":"print"},{"value":"1573-7322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,1]]}}}