{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T03:41:39Z","timestamp":1791258099511,"version":"4.1.0"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2016,2,15]],"date-time":"2016-02-15T00:00:00Z","timestamp":1455494400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Heart Fail Rev"],"published-print":{"date-parts":[[2016,9]]},"DOI":"10.1007\/s10741-016-9541-z","type":"journal-article","created":{"date-parts":[[2016,2,15]],"date-time":"2016-02-15T16:19:28Z","timestamp":1455553168000},"page":"529-538","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":47,"title":["Heart failure and orthostatic hypotension"],"prefix":"10.1007","volume":"21","author":[{"given":"Oleg","family":"Gorelik","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonid","family":"Feldman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natan","family":"Cohen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,2,15]]},"reference":[{"key":"9541_CR1","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1056\/NEJM198910053211407","volume":"321","author":"LA Lipsitz","year":"1989","unstructured":"Lipsitz LA (1989) Orthostatic hypotension in the elderly. N Engl J Med 321:952\u2013957","journal-title":"N Engl J Med"},{"key":"9541_CR2","first-page":"22","volume":"59","author":"A Sclater","year":"2004","unstructured":"Sclater A, Alagiakrishnan K (2004) Orthostatic hypotension: a primary care primer for assessment and treatment. Geriatrics 59:22\u201327","journal-title":"Geriatrics"},{"key":"9541_CR3","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/s10286-011-0119-5","volume":"21","author":"R Freeman","year":"2011","unstructured":"Freeman R, Wieling W, Axelrod FB, Benditt DG, Benarroch E, Biaggioni I, Cheshire WP, Chelimsky T, Cortelli P, Gibbons CH, Goldstein DS, Hainsworth R, Hilz MJ, Jacob G, Kaufmann H, Jordan J, Lipsitz LA, Levine BD, Low PA, Mathias C, Raj SR, Robertson D, Sandroni P, Schatz I, Schondorff R, Stewart JM, van Dijk JG (2011) Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome. Clin Auton Res 21:69\u201372","journal-title":"Clin Auton Res"},{"key":"9541_CR4","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1111\/joim.12021","volume":"273","author":"A Fedorowski","year":"2013","unstructured":"Fedorowski A, Melander O (2013) Syndromes of orthostatic intolerance: a hidden danger. J Intern Med 273:322\u2013335","journal-title":"J Intern Med"},{"key":"9541_CR5","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.jash.2013.04.006","volume":"7","author":"C Shibao","year":"2013","unstructured":"Shibao C, Lipsitz LA, Biaggioni I (2013) Evaluation and treatment of orthostatic hypotension. J Am Soc Hypertens 7:317\u2013324","journal-title":"J Am Soc Hypertens"},{"key":"9541_CR6","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1016\/j.jacc.2015.06.1084","volume":"66","author":"F Ricci","year":"2015","unstructured":"Ricci F, De Caterina R, Fedorowski A (2015) Orthostatic hypotension: epidemiology, prognosis, and treatment. J Am Coll Cardiol 66:848\u2013860","journal-title":"J Am Coll Cardiol"},{"key":"9541_CR7","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1093\/eurheartj\/ehp329","volume":"31","author":"A Fedorowski","year":"2010","unstructured":"Fedorowski A, Stavenow L, Hedblad B, Berglund G, Nilsson PM, Melander O (2010) Orthostatic hypotension predicts all-cause mortality and coronary events in middle-aged individuals (The Malmo Preventive Project). Eur Heart J 31:85\u201391","journal-title":"Eur Heart J"},{"key":"9541_CR8","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1093\/eurheartj\/ehv093","volume":"36","author":"F Ricci","year":"2015","unstructured":"Ricci F, Fedorowski A, Radico F, Romanello M, Tatasciore A, Di Nicola M, Zimarino M, De Caterina R (2015) Cardiovascular morbidity and mortality related to orthostatic hypotension: a meta-analysis of prospective observational studies. Eur Heart J 36:1609\u20131617","journal-title":"Eur Heart J"},{"key":"9541_CR9","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.ijcard.2015.05.060","volume":"195","author":"RH Chou","year":"2015","unstructured":"Chou RH, Liu CJ, Chao TF, Chen SJ, Tuan TC, Chen TJ, Chen SA (2015) Association between orthostatic hypotension, mortality, and cardiovascular disease in Asians. Int J Cardiol 195:40\u201344","journal-title":"Int J Cardiol"},{"key":"9541_CR10","doi-asserted-by":"crossref","first-page":"2290","DOI":"10.1161\/01.CIR.98.21.2290","volume":"98","author":"KH Masaki","year":"1998","unstructured":"Masaki KH, Schatz IJ, Burchfiel CM, Sharp DS, Chiu D, Foley D, Curb JD (1998) Orthostatic hypotension predicts mortality in elderly men: the Honolulu Heart Program. Circulation 98:2290\u20132295","journal-title":"Circulation"},{"key":"9541_CR11","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1161\/CIRCULATIONAHA.105.598722","volume":"114","author":"KM Rose","year":"2006","unstructured":"Rose KM, Eigenbrodt ML, Biga RL, Couper DJ, Light KC, Sharrett AR, Heiss G (2006) Orthostatic hypotension predicts mortality in middle-aged adults: the atherosclerosis risk in communities (ARIC) study. Circulation 114:630\u2013636","journal-title":"Circulation"},{"key":"9541_CR12","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.jash.2011.08.008","volume":"6","author":"C Feldstein","year":"2012","unstructured":"Feldstein C, Weder AB (2012) Orthostatic hypotension: a common, serious and underrecognized problem in hospitalized patients. J Am Soc Hypertens 6:27\u201339","journal-title":"J Am Soc Hypertens"},{"key":"9541_CR13","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/S0749-0690(05)70032-X","volume":"16","author":"PE McGann","year":"2000","unstructured":"McGann PE (2000) Comorbidity in heart failure in the elderly. Clin Geriatr Med 16:631\u2013648","journal-title":"Clin Geriatr Med"},{"key":"9541_CR14","doi-asserted-by":"crossref","first-page":"1816","DOI":"10.1111\/j.1532-5415.2008.01946.x","volume":"56","author":"GC Verwoert","year":"2008","unstructured":"Verwoert GC, Mattace-Raso FU, Hofman A, Heeringa J, Stricker BH, Breteler MM, Witteman JC (2008) Orthostatic hypotension and risk of cardiovascular disease in elderly people: the Rotterdam study. J Am Geriatr Soc 56:1816\u20131820","journal-title":"J Am Geriatr Soc"},{"key":"9541_CR15","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1038\/ajh.2010.150","volume":"23","author":"A Fedorowski","year":"2010","unstructured":"Fedorowski A, Engstr\u00f6m G, Hedblad B, Melander O (2010) Orthostatic hypotension predicts incidence of heart failure: the Malm\u00f6 preventive project. Am J Hypertens 23:1209\u20131215","journal-title":"Am J Hypertens"},{"key":"9541_CR16","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1161\/HYPERTENSIONAHA.111.188151","volume":"59","author":"CD Jones","year":"2012","unstructured":"Jones CD, Loehr L, Franceschini N, Rosamond WD, Chang PP, Shahar E, Couper DJ, Rose KM (2012) Orthostatic hypotension as a risk factor for incident heart failure: the atherosclerosis risk in communities study. Hypertension 59:913\u2013918","journal-title":"Hypertension"},{"key":"9541_CR17","doi-asserted-by":"crossref","first-page":"e63169","DOI":"10.1371\/journal.pone.0063169","volume":"8","author":"W Xin","year":"2013","unstructured":"Xin W, Lin Z, Li X (2013) Orthostatic hypotension and the risk of congestive heart failure: a meta-analysis of prospective cohort studies. PLoS One 8:e63169","journal-title":"PLoS One"},{"key":"9541_CR18","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1093\/gerona\/glt086","volume":"69","author":"K Alagiakrishnan","year":"2014","unstructured":"Alagiakrishnan K, Patel K, Desai RV, Ahmed MB, Fonarow GC, Forman DE, White M, Aban IB, Love TE, Aronow WS, Allman RM, Anker SD, Ahmed A (2014) Orthostatic hypotension and incident heart failure in community-dwelling older adults. J Gerontol A Biol Sci Med Sci 69:223\u2013230","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"9541_CR19","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1007\/BF03351506","volume":"13","author":"K Potocka-Plazak","year":"2001","unstructured":"Potocka-Plazak K, Plazak W (2001) Orthostatic hypotension in elderly women with congestive heart failure. Aging Clin Exp Res 13:378\u2013384","journal-title":"Aging Clin Exp Res"},{"key":"9541_CR20","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1080\/08037050510008968","volume":"14","author":"O Gorelik","year":"2005","unstructured":"Gorelik O, Fishlev G, Litvinov V, Almoznino-Sarafian D, Alon I, Shteinshnaider M, Chachashvily S, Modai D, Cohen N (2005) First morning standing up may be risky in acutely ill older inpatients. Blood Press 14:139\u2013143","journal-title":"Blood Press"},{"key":"9541_CR21","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.1093\/eurheartj\/ehs104","volume":"33","author":"JJ McMurray","year":"2012","unstructured":"McMurray JJ, Adamopoulos S, Anker SD, Auricchio A, B\u00f6hm M, Dickstein K, Falk V, Filippatos G, Fonseca C, Gomez-Sanchez MA, Jaarsma T, K\u00f8ber L, Lip GY, Maggioni AP, Parkhomenko A, Pieske BM, Popescu BA, R\u00f8nnevik PK, Rutten FH, Schwitter J, Seferovic P, Stepinska J, Trindade PT, Voors AA, Zannad F, Zeiher A (2012) ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: the task force for the diagnosis and treatment of acute and chronic heart failure 2012 of the European society of cardiology. Eur Heart J 33:1787\u20131847","journal-title":"Eur Heart J"},{"key":"9541_CR22","doi-asserted-by":"crossref","first-page":"e240","DOI":"10.1161\/CIR.0b013e31829e8807","volume":"128","author":"CW Yancy","year":"2013","unstructured":"Yancy CW, Jessup M, Bozkurt B, Butler J, Casey DE Jr, Drazner MH, Fonarow GC, Geraci SA, Horwich T, Januzzi JL, Johnson MR, Kasper EK, Levy WC, Masoudi FA, McBride PE, McMurray JJ, Mitchell JE, Peterson PN, Riegel B, Sam F, Stevenson LW, Tang WH, Tsai EJ, Wilkoff BL (2013) 2013 ACCF\/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation\/American Heart Association Task Force on practice guidelines. Circulation 128:e240\u2013e327","journal-title":"Circulation"},{"key":"9541_CR23","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.amjopharm.2009.10.001","volume":"7","author":"JW Cheng","year":"2009","unstructured":"Cheng JW, Nayar M (2009) A review of heart failure management in the elderly population. Am J Geriatr Pharmacother 7:233\u2013249","journal-title":"Am J Geriatr Pharmacother"},{"key":"9541_CR24","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/0002-9149(69)90515-3","volume":"23","author":"WH Abelmann","year":"1969","unstructured":"Abelmann WH, Fareeduddin K (1969) Increased tolerance of orthostatic stress in patients with heart disease. Am J Cardiol 23:354\u2013363","journal-title":"Am J Cardiol"},{"key":"9541_CR25","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1161\/01.CIR.66.1.135","volume":"66","author":"RJ Cody","year":"1982","unstructured":"Cody RJ, Franklin KW, Kluger J, Laragh JH (1982) Mechanisms governing the postural response and baroreceptor abnormalities in chronic congestive heart failure: effects of acute and long-term converting-enzyme inhibition. Circulation 66:135\u2013142","journal-title":"Circulation"},{"key":"9541_CR26","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/0002-9149(83)90017-6","volume":"52","author":"SH Kubo","year":"1983","unstructured":"Kubo SH, Cody RJ (1983) Circulatory autoregulation in chronic congestive heart failure: responses to head-up tilt in 41 patients. Am J Cardiol 52:512\u2013518","journal-title":"Am J Cardiol"},{"key":"9541_CR27","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/0002-8703(82)90333-7","volume":"103","author":"RJ Cody","year":"1982","unstructured":"Cody RJ, Franklin KW, Laragh JH (1982) Postural hypotension during tilt with chronic captopril and diuretic therapy of severe congestive heat failure. Am Heart J 103:480\u2013484","journal-title":"Am Heart J"},{"key":"9541_CR28","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1016\/S0002-9149(02)02562-6","volume":"90","author":"DJ Mehagnoul-Schipper","year":"2002","unstructured":"Mehagnoul-Schipper DJ, Colier WN, Hoefnagels WH, Verheugt FW, Jansen RW (2002) Effects of furosemide versus captopril on postprandial and orthostatic blood pressure and on cerebral oxygenation in patients \u226570\u00a0years of age with heart failure. Am J Cardiol 90:596\u2013600","journal-title":"Am J Cardiol"},{"key":"9541_CR29","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1001\/archinte.1995.00430090067008","volume":"155","author":"I R\u00e4ih\u00e4","year":"1995","unstructured":"R\u00e4ih\u00e4 I, Luutonen S, Piha J, Sepp\u00e4nen A, Toikka T, Sourander L (1995) Prevalence, predisposing factors, and prognostic importance of postural hypotension. Arch Intern Med 155:930\u2013935","journal-title":"Arch Intern Med"},{"key":"9541_CR30","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1185\/03007998809114241","volume":"11","author":"D Heseltine","year":"1988","unstructured":"Heseltine D, Bramble MG (1988) Loop diuretics cause less postural hypotension than thiazide diuretics in the frail elderly. Curr Med Res Opin 11:232\u2013235","journal-title":"Curr Med Res Opin"},{"key":"9541_CR31","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1097\/MBP.0b013e3282fd16f8","volume":"13","author":"JM Mallion","year":"2008","unstructured":"Mallion JM, Neuder Y, Ormezzano O, Rochette GB, Salvat M, Baguet JP (2008) Study of nycthemeral variations in blood pressure in patients with heart failure. Blood Press Monit 13:163\u2013165","journal-title":"Blood Press Monit"},{"key":"9541_CR32","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1161\/01.CIR.63.3.658","volume":"63","author":"B Massie","year":"1981","unstructured":"Massie B, Kramer B, Haughom F (1981) Postural hypotension and tachycardia during hydralazine-isosorbide dinitrate therapy for chronic heart failure. Circulation 63:658\u2013664","journal-title":"Circulation"},{"key":"9541_CR33","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1159\/000141920","volume":"55","author":"O Gorelik","year":"2009","unstructured":"Gorelik O, Almoznino-Sarafian D, Litvinov V, Alon I, Shteinshnaider M, Dotan E, Modai D, Cohen N (2009) Seating-induced postural hypotension is common in older patients with decompensated heart failure and may be prevented by lower limb compression bandaging. Gerontology 55:138\u2013144","journal-title":"Gerontology"},{"key":"9541_CR34","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1016\/j.jash.2015.10.001","volume":"9","author":"O Gorelik","year":"2015","unstructured":"Gorelik O, Cohen N (2015) Seated postural hypotension. J Am Soc Hypertens 9:985\u2013992","journal-title":"J Am Soc Hypertens"},{"key":"9541_CR35","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1093\/ajh\/hpv022","volume":"28","author":"N Veronese","year":"2015","unstructured":"Veronese N, De Rui M, Bolzetta F, Zambon S, Corti MC, Baggio G, Toffanello ED, Maggi S, Crepaldi G, Perissinotto E, Manzato E, Sergi G (2015) Orthostatic changes in blood pressure and mortality in the elderly: the Pro.V.A study. Am J Hypertens 28:1248\u20131256","journal-title":"Am J Hypertens"},{"key":"9541_CR36","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1111\/j.1525-1497.2006.00450.x","volume":"21","author":"A Weiss","year":"2006","unstructured":"Weiss A, Beloosesky Y, Kornowski R, Yalov A, Grinblat J, Grossman E (2006) Influence of orthostatic hypotension on mortality among patients discharged from an acute geriatric ward. J Gen Intern Med 21:602\u2013606","journal-title":"J Gen Intern Med"},{"key":"9541_CR37","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1016\/j.amjmed.2008.10.040","volume":"122","author":"SD Arbogast","year":"2009","unstructured":"Arbogast SD, Alshekhlee A, Hussain Z, McNeeley K, Chelimsky TC (2009) Hypotension unawareness in profound orthostatic hypotension. Am J Med 122:574\u2013580","journal-title":"Am J Med"},{"key":"9541_CR38","first-page":"775","volume":"66","author":"E Kristal-Boneh","year":"1995","unstructured":"Kristal-Boneh E, Harari G, Weinstein Y, Green MS (1995) Factors affecting differences in supine, sitting, and standing heart rate: the Israeli CORDIS study. Aviat Space Environ Med 66:775\u2013779","journal-title":"Aviat Space Environ Med"},{"key":"9541_CR39","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1097\/HJH.0b013e3283279860","volume":"27","author":"A Fedorowski","year":"2009","unstructured":"Fedorowski A, Burri P, Melander O (2009) Orthostatic hypotension in genetically related hypertensive and normotensive individuals. J Hypertens 27:976\u2013982","journal-title":"J Hypertens"},{"key":"9541_CR40","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1002\/j.1552-4604.1994.tb04980.x","volume":"34","author":"CM Lathers","year":"1994","unstructured":"Lathers CM, Charles JB (1994) Orthostatic hypotension in patients, bed rest subjects, and astronauts. J Clin Pharmacol 34:403\u2013417","journal-title":"J Clin Pharmacol"},{"key":"9541_CR41","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/0002-9149(92)90599-T","volume":"70","author":"JN Cohn","year":"1992","unstructured":"Cohn JN (1992) Mechanisms of action and efficacy of nitrates in heart failure. Am J Cardiol 70:88\u201392B","journal-title":"Am J Cardiol"},{"key":"9541_CR42","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1159\/000081007","volume":"102","author":"O Gorelik","year":"2004","unstructured":"Gorelik O, Fishlev G, Almoznino-Sarafian D, Alon I, Weissgarten J, Shteinshnaider M, Chachashvily S, Modai D, Cohen N (2004) Lower limb compression bandaging is effective in preventing signs and symptoms of seating-induced postural hypotension. Cardiology 102:177\u2013183","journal-title":"Cardiology"},{"key":"9541_CR43","doi-asserted-by":"crossref","first-page":"248","DOI":"10.3109\/08037051.2013.871787","volume":"23","author":"O Gorelik","year":"2014","unstructured":"Gorelik O, Shteinshnaider M, Tzur I, Feldman L, Cohen N, Almoznino-Sarafian D (2014) Factors associated with prevention of postural hypotension by leg compression bandaging. Blood Press 23:248\u2013254","journal-title":"Blood Press"},{"key":"9541_CR44","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1093\/ajh\/hpt172","volume":"27","author":"E Casiglia","year":"2014","unstructured":"Casiglia E, Tikhonoff V, Caffi S, Boschetti G, Giordano N, Guidotti F, Segato F, Mazza A, Grasselli C, Saugo M, Rigoni G, Guglielmi F, Martini B, Palatini P (2014) Orthostatic hypotension does not increase cardiovascular risk in the elderly at a population level. Am J Hypertens 27:81\u201388","journal-title":"Am J Hypertens"}],"container-title":["Heart Failure Reviews"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10741-016-9541-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10741-016-9541-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10741-016-9541-z","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,30]],"date-time":"2019-05-30T23:01:31Z","timestamp":1559257291000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10741-016-9541-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2,15]]},"references-count":44,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016,9]]}},"alternative-id":["9541"],"URL":"https:\/\/doi.org\/10.1007\/s10741-016-9541-z","relation":{},"ISSN":["1382-4147","1573-7322"],"issn-type":[{"value":"1382-4147","type":"print"},{"value":"1573-7322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,2,15]]}}}