{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T05:59:42Z","timestamp":1787983182063,"version":"build-2784847793"},"reference-count":83,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2019,3,14]],"date-time":"2019-03-14T00:00:00Z","timestamp":1552521600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Heart Fail Rev"],"published-print":{"date-parts":[[2019,7]]},"DOI":"10.1007\/s10741-019-09771-8","type":"journal-article","created":{"date-parts":[[2019,3,14]],"date-time":"2019-03-14T06:13:39Z","timestamp":1552544019000},"page":"461-472","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["READY: relative efficacy of loop diuretics in patients with chronic systolic heart failure\u2014a systematic review and network meta-analysis of randomised trials"],"prefix":"10.1007","volume":"24","author":[{"given":"Tobias","family":"T\u00e4ger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanna","family":"Fr\u00f6hlich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirjam","family":"Seiz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugo A.","family":"Katus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7216-1004","authenticated-orcid":false,"given":"Lutz","family":"Frankenstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,3,14]]},"reference":[{"key":"9771_CR1","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1016\/j.ahj.2004.08.005","volume":"149","author":"KF Adams Jr","year":"2005","unstructured":"Adams KF Jr, Fonarow GC, Emerman CL, LeJemtel TH, Costanzo MR, Abraham WT, Berkowitz RL, Galvao M, Horton DP (2005) Characteristics and outcomes of patients hospitalized for heart failure in the United States: rationale, design, and preliminary observations from the first 100,000 cases in the Acute Decompensated Heart Failure National Registry (ADHERE). Am Heart J 149:209\u2013216","journal-title":"Am Heart J"},{"key":"9771_CR2","doi-asserted-by":"publisher","first-page":"1431","DOI":"10.1093\/eurheartj\/ehi890","volume":"27","author":"A Ahmed","year":"2006","unstructured":"Ahmed A, Husain A, Love TE, Gambassi G, Dell'Italia LJ, Francis GS, Gheorghiade M, Allman RM, Meleth S, Bourge RC (2006) Heart failure, chronic diuretic use, and increase in mortality and hospitalization: an observational study using propensity score methods. Eur Heart J 27:1431\u20131439","journal-title":"Eur Heart J"},{"issue":"Suppl 2","key":"9771_CR3","first-page":"17b","volume":"18","author":"S Allman","year":"1990","unstructured":"Allman S, Norris RJ (1990) An open, parallel group study comparing a frusemide\/amiloride diuretic and a diuretic containing cyclopenthiazide with sustained release potassium in the treatment of congestive cardiac failure--a multicentre general practice study. J Int Med Res 18(Suppl 2):17b\u201323b","journal-title":"J Int Med Res"},{"key":"9771_CR4","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1536\/ihj.16-290","volume":"58","author":"M Asami","year":"2017","unstructured":"Asami M, Aoki J, Tanimoto S, Horiuchi Y, Watanabe M, Furui K, Yasuhara K, Sato T, Tanabe K, Hara K (2017) Effects of long-acting loop diuretics in heart failure with reduced ejection fraction patients with cardiac resynchronization therapy. Int Heart J 58:211\u2013219","journal-title":"Int Heart J"},{"key":"9771_CR5","doi-asserted-by":"publisher","first-page":"1549","DOI":"10.1016\/j.jacc.2012.12.043","volume":"61","author":"B Bikdeli","year":"2013","unstructured":"Bikdeli B, Strait KM, Dharmarajan K, Partovian C, Coca SG, Kim N, Li SX, Testani JM, Khan U, Krumholz HM (2013) Dominance of furosemide for loop diuretic therapy in heart failure: time to revisit the alternatives? J Am Coll Cardiol 61:1549\u20131550","journal-title":"J Am Coll Cardiol"},{"key":"9771_CR6","doi-asserted-by":"publisher","first-page":"708","DOI":"10.1002\/j.1552-4604.1998.tb04810.x","volume":"38","author":"BE Bleske","year":"1998","unstructured":"Bleske BE, Welage LS, Kramer WG, Nicklas JM (1998) Pharmacokinetics of torsemide in patients with decompensated and compensated congestive heart failure. J Clin Pharmacol 38:708\u2013714","journal-title":"J Clin Pharmacol"},{"key":"9771_CR7","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1016\/j.ahj.2014.12.009","volume":"169","author":"J Buggey","year":"2015","unstructured":"Buggey J, Mentz RJ, Pitt B, Eisenstein EL, Anstrom KJ, Velazquez EJ, O'Connor CM (2015) A reappraisal of loop diuretic choice in heart failure patients. Am Heart J 169:323\u2013333","journal-title":"Am Heart J"},{"key":"9771_CR8","doi-asserted-by":"publisher","first-page":"e76654","DOI":"10.1371\/journal.pone.0076654","volume":"8","author":"A Chaimani","year":"2013","unstructured":"Chaimani A, Higgins JP, Mavridis D et al (2013) Graphical tools for network meta-analysis in STATA. PLoS One 8:e76654","journal-title":"PLoS One"},{"key":"9771_CR9","first-page":"157","volume":"16","author":"RR Chaudhury","year":"1968","unstructured":"Chaudhury RR, Chugh KS, Gupta GS et al (1968) A controlled clinical trial comparing the diuretic furosemide and hydrochlorothiazide. J Assoc Physicians India 16:157\u2013163","journal-title":"J Assoc Physicians India"},{"key":"9771_CR10","doi-asserted-by":"publisher","first-page":"480","DOI":"10.1016\/0002-8703(82)90333-7","volume":"103","author":"RJ Cody","year":"1982","unstructured":"Cody RJ, Franklin KW, Laragh JH (1982) Postural hypotension during tilt with chronic captopril and diuretic therapy of severe congestive heart failure. Am Heart J 103:480\u2013484","journal-title":"Am Heart J"},{"key":"9771_CR11","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1016\/S1388-9842(02)00122-8","volume":"4","author":"J Cosin","year":"2002","unstructured":"Cosin J, Diez J, Investigators T (2002) Torasemide in chronic heart failure: results of the TORIC study. Eur J Heart Fail 4:507\u2013513","journal-title":"Eur J Heart Fail"},{"key":"9771_CR12","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1177\/030006058801600209","volume":"16","author":"RJ Crawford","year":"1988","unstructured":"Crawford RJ, Allman S, Gibson W, Kitchen S, Richards HH (1988) A comparative study of frusemide-amiloride and cyclopenthiazide-potassium chloride in the treatment of congestive cardiac failure in general practice. J Int Med Res 16:143\u2013149","journal-title":"J Int Med Res"},{"key":"9771_CR13","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1002\/ejhf.462","volume":"18","author":"K Damman","year":"2016","unstructured":"Damman K, Kjekshus J, Wikstrand J, Cleland JGF, Komajda M, Wedel H, Waagstein F, McMurray JJV (2016) Loop diuretics, renal function and clinical outcome in patients with heart failure and reduced ejection fraction. Eur J Heart Fail 18:328\u2013336","journal-title":"Eur J Heart Fail"},{"key":"9771_CR14","doi-asserted-by":"publisher","first-page":"656","DOI":"10.1111\/ijcp.12144","volume":"67","author":"FL Dini","year":"2013","unstructured":"Dini FL, Ghio S, Klersy C, Rossi A, Simioniuc A, Scelsi L, Genta FT, Cicoira M, Tavazzi L, Temporelli PL (2013) Effects on survival of loop diuretic dosing in ambulatory patients with chronic heart failure using a propensity score analysis. Int J Clin Pract 67:656\u2013664","journal-title":"Int J Clin Pract"},{"key":"9771_CR15","doi-asserted-by":"publisher","first-page":"707","DOI":"10.2217\/fca.12.54","volume":"8","author":"JJ Dinicolantonio","year":"2012","unstructured":"Dinicolantonio JJ (2012) Should torsemide be the loop diuretic of choice in systolic heart failure? Futur Cardiol 8:707\u2013728","journal-title":"Futur Cardiol"},{"key":"9771_CR16","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1016\/S0735-1097(03)00765-4","volume":"42","author":"M Domanski","year":"2003","unstructured":"Domanski M, Norman J, Pitt B, Haigney M, Hanlon S, Peyster E, Studies of Left Ventricular Dysfunction (2003) Diuretic use, progressive heart failure, and death in patients in the Studies Of Left Ventricular Dysfunction (SOLVD). J Am Coll Cardiol 42:705\u2013708","journal-title":"J Am Coll Cardiol"},{"key":"9771_CR17","doi-asserted-by":"crossref","unstructured":"Faris RF, Flather M, Purcell H et al (2012) Diuretics for heart failure. Cochrane Database Syst Rev:CD003838","DOI":"10.1002\/14651858.CD003838.pub3"},{"key":"9771_CR18","doi-asserted-by":"crossref","unstructured":"Ferrara N, Leosco D, Del P et al (1997) Torasemide versus furosemide in patients with congestive heart failure: a double-masked, randomized study. Curr Ther Res Clin Exp:291\u2013299","DOI":"10.1016\/S0011-393X(97)80026-4"},{"key":"9771_CR19","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1007\/BF00541540","volume":"30","author":"AJ Funke Kupper","year":"1986","unstructured":"Funke Kupper AJ, Fintelman H, Huige MC et al (1986) Cross-over comparison of the fixed combination of hydrochlorothiazide and triamterene and the free combination of furosemide and triamterene in the maintenance treatment of congestive heart failure. Eur J Clin Pharmacol 30:341\u2013343","journal-title":"Eur J Clin Pharmacol"},{"key":"9771_CR20","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1136\/pgmj.57.664.71","volume":"57","author":"R Gabriel","year":"1981","unstructured":"Gabriel R, Baylor P (1981) Comparison of the chronic effects of bendrofluazide, bumetanide and frusemide on plasma biochemical variables. Postgrad Med J 57:71\u201374","journal-title":"Postgrad Med J"},{"key":"9771_CR21","first-page":"1051","volume":"15","author":"KM Goebel","year":"1993","unstructured":"Goebel KM (1993) Six-week study of torsemide in patients with congestive heart failure. Clin Ther 15:1051\u20131059","journal-title":"Clin Ther"},{"key":"9771_CR22","doi-asserted-by":"publisher","first-page":"1204","DOI":"10.1016\/j.clinthera.2011.08.006","volume":"33","author":"Group. TTI","year":"2011","unstructured":"Group. TTI (2011) Effects of prolonged-release torasemide versus furosemide on myocardial fibrosis in hypertensive patients with chronic heart failure: a randomized, blinded-end point, active-controlled study. Clin Ther 33:1204\u20131213.e1203","journal-title":"Clin Ther"},{"key":"9771_CR23","doi-asserted-by":"publisher","first-page":"746","DOI":"10.1093\/eurjhf\/hfq090","volume":"12","author":"S Gupta","year":"2010","unstructured":"Gupta S, Waywell C, Gandhi N, Clayton N, Keevil B, Clark AL, Ng LL, Brooks N, Neyses L (2010) The effects of adding torasemide to standard therapy on peak oxygen consumption, natriuretic peptides, and quality of life in patients with compensated left ventricular systolic dysfunction. Eur J Heart Fail 12:746\u2013752","journal-title":"Eur J Heart Fail"},{"key":"9771_CR24","doi-asserted-by":"publisher","first-page":"1154","DOI":"10.1016\/0735-1097(94)00543-Y","volume":"25","author":"SA Hall","year":"1995","unstructured":"Hall SA, Cigarroa CG, Marcoux L, Risser RC, Grayburn PA, Eichhorn EJ (1995) Time course of improvement in left ventricular function, mass and geometry in patients with congestive heart failure treated with beta-adrenergic blockade. J Am Coll Cardiol 25:1154\u20131161","journal-title":"J Am Coll Cardiol"},{"key":"9771_CR25","doi-asserted-by":"publisher","first-page":"1920","DOI":"10.1253\/circj.CJ-11-1196","volume":"76","author":"S Hamaguchi","year":"2012","unstructured":"Hamaguchi S, Kinugawa S, Tsuchihashi-Makaya M, Goto D, Yamada S, Yokoshiki H, Takeshita A, Tsutsui H, The JCARE-CARD Investigators (2012) Loop diuretic use at discharge is associated with adverse outcomes in hospitalized patients with heart failure: a report from the Japanese cardiac registry of heart failure in cardiology (JCARE-CARD). Circ J 76:1920\u20131927","journal-title":"Circ J"},{"key":"9771_CR26","doi-asserted-by":"publisher","first-page":"7262","DOI":"10.4238\/2014.September.5.11","volume":"13","author":"LN Han","year":"2014","unstructured":"Han LN, Guo SL, Lin XM, Shi XM, Zang CB, Yang LM, Ding GL (2014) Torasemide reduces dilated cardiomyopathy, complication of arrhythmia, and progression to heart failure. Genet Mol Res 13:7262\u20137274","journal-title":"Genet Mol Res"},{"key":"9771_CR27","doi-asserted-by":"publisher","first-page":"468","DOI":"10.1097\/FJC.0b013e3181a717f7","volume":"53","author":"K Harada","year":"2009","unstructured":"Harada K, Izawa H, Nishizawa T, Hirashiki A, Murase Y, Kobayashi M, Isobe S, Cheng XW, Noda A, Nagata K, Yokota M, Murohara T (2009) Beneficial effects of torasemide on systolic wall stress and sympathetic nervous activity in asymptomatic or mildly symptomatic patients with heart failure: comparison with azosemide. J Cardiovasc Pharmacol 53:468\u2013473","journal-title":"J Cardiovasc Pharmacol"},{"key":"9771_CR28","unstructured":"Higgins J, Green S, (Editors) Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. In:The Cochrane Collaboration, 2011"},{"key":"9771_CR29","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1002\/jrsm.1044","volume":"3","author":"JP Higgins","year":"2012","unstructured":"Higgins JP, Jackson D, Barrett JK et al (2012) Consistency and inconsistency in network meta-analysis: concepts and models for multi-arm studies. Res Synth Methods 3:98\u2013110","journal-title":"Res Synth Methods"},{"key":"9771_CR30","doi-asserted-by":"publisher","first-page":"892","DOI":"10.1093\/eurjhf\/hfr054","volume":"13","author":"S Hisatake","year":"2011","unstructured":"Hisatake S, Nanjo S, Fujimoto S, Yamashina S, Yuzawa H, Namiki A, Nakano H, Yamazaki J (2011) Comparative analysis of the therapeutic effects of long-acting and short-acting loop diuretics in the treatment of chronic heart failure using (123)I-metaiodobenzylguanidine scintigraphy. Eur J Heart Fail 13:892\u2013898","journal-title":"Eur J Heart Fail"},{"key":"9771_CR31","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1136\/pgmj.61.711.29","volume":"61","author":"M Hussain","year":"1985","unstructured":"Hussain M, Walton K, Davidson C, Morgan DB (1985) A study of two diuretic\/potassium combinations in heart failure. Postgrad Med J 61:29\u201333","journal-title":"Postgrad Med J"},{"key":"9771_CR32","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1016\/j.medcli.2016.02.025","volume":"147","author":"B Hutton","year":"2016","unstructured":"Hutton B, Catala-Lopez F, Moher D (2016) The PRISMA statement extension for systematic reviews incorporating network meta-analysis: PRISMA-NMA. Med Clin 147:262\u2013266","journal-title":"Med Clin"},{"key":"9771_CR33","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1016\/j.jval.2014.01.004","volume":"17","author":"JP Jansen","year":"2014","unstructured":"Jansen JP, Trikalinos T, Cappelleri JC, Daw J, Andes S, Eldessouki R, Salanti G (2014) Indirect treatment comparison\/network meta-analysis study questionnaire to assess relevance and credibility to inform health care decision making: an ISPOR-AMCP-NPC Good Practice Task Force report. Value Health 17:157\u2013173","journal-title":"Value Health"},{"key":"9771_CR34","doi-asserted-by":"publisher","first-page":"1434","DOI":"10.1136\/hrt.2005.079764","volume":"92","author":"S Kasama","year":"2006","unstructured":"Kasama S, Toyama T, Hatori T, Sumino H, Kumakura H, Takayama Y, Ichikawa S, Suzuki T, Kurabayashi M (2006) Effects of torasemide on cardiac sympathetic nerve activity and left ventricular remodelling in patients with congestive heart failure. Heart 92:1434\u20131440","journal-title":"Heart"},{"key":"9771_CR35","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1016\/S0195-668X(02)00700-5","volume":"24","author":"M Komajda","year":"2003","unstructured":"Komajda M, Follath F, Swedberg K, Cleland J, Aguilar JC, Cohen-Solal A, Dietz R, Gavazzi A, van Gilst W, Hobbs R, Korewicki J, Madeira HC, Moiseyev VS, Preda I, Widimsky J, Freemantle N, Eastaugh J, Mason J, Study Group on Diagnosis of the Working Group on Heart Failure of the European Society of Cardiology (2003) The EuroHeart Failure Survey programme--a survey on the quality of care among patients with heart failure in Europe. Part 2: treatment. Eur Heart J 24:464\u2013474","journal-title":"Eur Heart J"},{"key":"9771_CR36","doi-asserted-by":"publisher","first-page":"688","DOI":"10.1002\/j.1552-4604.1981.tb05684.x","volume":"21","author":"LL Konecke","year":"1981","unstructured":"Konecke LL (1981) Clinical trial of bumetanide versus furosemide in patients with congestive heart failure. J Clin Pharmacol 21:688\u2013690","journal-title":"J Clin Pharmacol"},{"key":"9771_CR37","first-page":"1165","volume":"103","author":"D Kremer","year":"1983","unstructured":"Kremer D (1983) Treatment of cardiac failure with diuretics. A double-blind study comparing a fixed combination of hydrochlorothiazide\/amiloride and furosemide plus potassium substitution. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 103:1165\u20131168","journal-title":"Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke"},{"key":"9771_CR38","doi-asserted-by":"publisher","first-page":"420","DOI":"10.1002\/j.1552-4604.1977.tb04625.x","volume":"17","author":"B Levy","year":"1977","unstructured":"Levy B (1977) The efficacy and safety of furosemide and a combination of spironolactone and hydrochlorothiazide in congestive heart failure. J Clin Pharmacol 17:420\u2013430","journal-title":"J Clin Pharmacol"},{"key":"9771_CR39","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1093\/ckj\/sfs160","volume":"6","author":"JA Lopes","year":"2013","unstructured":"Lopes JA, Jorge S (2013) The RIFLE and AKIN classifications for acute kidney injury: a critical and comprehensive review. Clin Kidney J 6:8\u201314","journal-title":"Clin Kidney J"},{"key":"9771_CR40","doi-asserted-by":"publisher","first-page":"2028","DOI":"10.1016\/j.jacc.2003.12.052","volume":"43","author":"B Lopez","year":"2004","unstructured":"Lopez B, Querejeta R, Gonzalez A et al (2004) Effects of loop diuretics on myocardial fibrosis and collagen type I turnover in chronic heart failure. J Am Coll Cardiol 43:2028\u20132035","journal-title":"J Am Coll Cardiol"},{"key":"9771_CR41","doi-asserted-by":"publisher","first-page":"859","DOI":"10.1016\/j.jacc.2007.04.080","volume":"50","author":"B Lopez","year":"2007","unstructured":"Lopez B, Gonzalez A, Beaumont J et al (2007) Identification of a potential cardiac antifibrotic mechanism of torasemide in patients with chronic heart failure. J Am Coll Cardiol 50:859\u2013867","journal-title":"J Am Coll Cardiol"},{"key":"9771_CR42","unstructured":"Mareev V, Mareev Y, Vygodin V et al (2017) Mortality and rehospitalization data from diuretic therapy with effective doses of oral torasemide and furosemide in treatment of patients with exacerbation of chronic heart failure (DUEL-CHF) trial. In: European journal of heart failure. Conference: heart failure 2016 and the 3rd world congress on acute heart failure. Florence Italy. Conference start: 20160521. Conference end: 20160524. Conference publication: (var.pagings). P 382-383"},{"key":"9771_CR43","doi-asserted-by":"publisher","first-page":"833","DOI":"10.1253\/circj.CJ-11-1500","volume":"76","author":"T Masuyama","year":"2012","unstructured":"Masuyama T, Tsujino T, Origasa H, Yamamoto K, Akasaka T, Hirano Y, Ohte N, Daimon T, Nakatani S, Ito H (2012) Superiority of long-acting to short-acting loop diuretics in the treatment of congestive heart failure. Circ J 76:833\u2013842","journal-title":"Circ J"},{"key":"9771_CR44","doi-asserted-by":"publisher","first-page":"e000276","DOI":"10.1136\/openhrt-2015-000276","volume":"3","author":"Y Matsuo","year":"2016","unstructured":"Matsuo Y, Kasama S, Toyama T, Funada R, Takama N, Koitabashi N, Ichikawa S, Suzuki Y, Matsumoto N, Sato Y, Kurabayashi M (2016) Comparative effects of long-acting and short-acting loop diuretics on cardiac sympathetic nerve activity in patients with chronic heart failure. Open Heart 3:e000276","journal-title":"Open Heart"},{"key":"9771_CR45","first-page":"205","volume":"135","author":"H Mauersberger","year":"1985","unstructured":"Mauersberger H, Rangoonwala B, Ehrlich E (1985) Comparative study of 2 diuretic-containing combination preparations in patients with edematous heart failure. Wien Med Wochenschr (1946) 135:205\u2013213","journal-title":"Wien Med Wochenschr (1946)"},{"key":"9771_CR46","doi-asserted-by":"publisher","first-page":"585","DOI":"10.2217\/fca.15.56","volume":"11","author":"RJ Mentz","year":"2015","unstructured":"Mentz RJ, Velazquez EJ, Metra M, McKendry C, Chiswell K, Fiuzat M, Givertz MM, Voors AA, Teerlink JR, O'Connor CM (2015) Comparative effectiveness of torsemide versus furosemide in heart failure patients: insights from the PROTECT trial. Futur Cardiol 11:585\u2013595","journal-title":"Futur Cardiol"},{"key":"9771_CR47","doi-asserted-by":"publisher","first-page":"404","DOI":"10.1016\/j.amjcard.2015.10.059","volume":"117","author":"RJ Mentz","year":"2016","unstructured":"Mentz RJ, Hasselblad V, Devore AD et al (2016) Torsemide versus furosemide in patients with acute heart failure (from the ASCEND-HF Trial). Am J Cardiol 117:404\u2013411","journal-title":"Am J Cardiol"},{"key":"9771_CR48","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1016\/j.jjcc.2011.12.007","volume":"59","author":"M Miyata","year":"2012","unstructured":"Miyata M, Sasaki T, Ikeda Y, Shinsato T, Kubozono T, Furusho Y, Kusumoto A, Hamasaki S, Tei C, COLD-CHF Investigators (2012) Comparative study of therapeutic effects of short- and long-acting loop diuretics in outpatients with chronic heart failure (COLD-CHF). J Cardiol 59:352\u2013358","journal-title":"J Cardiol"},{"key":"9771_CR49","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/2046-4053-4-1","volume":"4","author":"D Moher","year":"2015","unstructured":"Moher D, Shamseer L, Clarke M et al (2015) Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement. Syst Rev 4:1","journal-title":"Syst Rev"},{"key":"9771_CR50","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1186\/s13643-016-0191-y","volume":"5","author":"D Moher","year":"2016","unstructured":"Moher D, Stewart L, Shekelle P (2016) Implementing PRISMA-P: recommendations for prospective authors. Syst Rev 5:15","journal-title":"Syst Rev"},{"key":"9771_CR51","doi-asserted-by":"publisher","first-page":"793","DOI":"10.1016\/S1388-9842(03)00150-8","volume":"5","author":"K Muller","year":"2003","unstructured":"Muller K, Gamba G, Jaquet F et al (2003) Torasemide vs. furosemide in primary care patients with chronic heart failure NYHA II to IV--efficacy and quality of life. Eur J Heart Fail 5:793\u2013801","journal-title":"Eur J Heart Fail"},{"key":"9771_CR52","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1016\/S0002-9343(01)00903-2","volume":"111","author":"MD Murray","year":"2001","unstructured":"Murray MD, Deer MM, Ferguson JA, Dexter PR, Bennett SJ, Perkins SM, Smith FE, Lane KA, Adams LD, Tierney WM, Brater DC (2001) Open-label randomized trial of torsemide compared with furosemide therapy for patients with heart failure. Am J Med 111:513\u2013520","journal-title":"Am J Med"},{"key":"9771_CR53","doi-asserted-by":"publisher","first-page":"854","DOI":"10.1016\/S0149-2918(99)80007-1","volume":"21","author":"LL Noe","year":"1999","unstructured":"Noe LL, Vreeland MG, Pezzella SM, Trotter JP (1999) A pharmacoeconomic assessment of torsemide and furosemide in the treatment of patients with congestive heart failure. Clin Ther 21:854\u2013866","journal-title":"Clin Ther"},{"key":"9771_CR54","doi-asserted-by":"publisher","first-page":"398","DOI":"10.1016\/j.ijcard.2013.12.039","volume":"171","author":"K Ogino","year":"2014","unstructured":"Ogino K, Kinugasa Y, Kato M, Yamamoto K, Hisatome I, Anker SD, Doehner W (2014) Spironolactone, not furosemide, improved insulin resistance in patients with chronic heart failure. Int J Cardiol 171:398\u2013403","journal-title":"Int J Cardiol"},{"key":"9771_CR55","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1161\/01.CIR.68.4.803","volume":"68","author":"M Packer","year":"1983","unstructured":"Packer M, Medina N, Yushak M, Meller J (1983) Hemodynamic patterns of response during long-term captopril therapy for severe chronic heart failure. Circulation 68:803\u2013812","journal-title":"Circulation"},{"key":"9771_CR56","doi-asserted-by":"publisher","first-page":"346","DOI":"10.7326\/0003-4819-106-3-346","volume":"106","author":"M Packer","year":"1987","unstructured":"Packer M, Lee WH, Medina N, Yushak M, Kessler PD (1987) Functional renal insufficiency during long-term therapy with captopril and enalapril in severe chronic heart failure. Ann Intern Med 106:346\u2013354","journal-title":"Ann Intern Med"},{"key":"9771_CR57","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1016\/0167-5273(93)90004-Z","volume":"40","author":"JO Parker","year":"1993","unstructured":"Parker JO (1993) The effects of oral ibopamine in patients with mild heart failure--a double blind placebo controlled comparison to furosemide. The Ibopamine Study Group. Int J Cardiol 40:221\u2013227","journal-title":"Int J Cardiol"},{"key":"9771_CR58","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1007\/BF00543315","volume":"28","author":"SK Pehrsson","year":"1985","unstructured":"Pehrsson SK (1985) Multicentre comparison between slow-release furosemide and bendroflumethiazide in congestive heart failure. Eur J Clin Pharmacol 28:235\u2013239","journal-title":"Eur J Clin Pharmacol"},{"key":"9771_CR59","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1007\/s10557-016-6697-7","volume":"30","author":"P Pellicori","year":"2016","unstructured":"Pellicori P, Cleland JG, Zhang J et al (2016) Cardiac dysfunction, congestion and loop diuretics: their relationship to prognosis in heart failure. Cardiovasc Drugs Ther 30:599\u2013609","journal-title":"Cardiovasc Drugs Ther"},{"key":"9771_CR60","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1056\/NEJM199909023411001","volume":"341","author":"B Pitt","year":"1999","unstructured":"Pitt B, Zannad F, Remme WJ et al (1999) The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. N Engl J Med 341:709\u2013717","journal-title":"N Engl J Med"},{"key":"9771_CR61","doi-asserted-by":"publisher","first-page":"2129","DOI":"10.1093\/eurheartj\/ehw128","volume":"37","author":"P Ponikowski","year":"2016","unstructured":"Ponikowski P, Voors AA, Anker SD, Bueno H, Cleland JGF, Coats AJS, Falk V, Gonz\u00e1lez-Juanatey JR, Harjola VP, Jankowska EA, Jessup M, Linde C, Nihoyannopoulos P, Parissis JT, Pieske B, Riley JP, Rosano GMC, Ruilope LM, Ruschitzka F, Rutten FH, van der Meer P, ESC Scientific Document Group (2016) 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: the Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC)Developed with the special contribution of the Heart Failure Association (HFA) of the ESC. Eur Heart J 37:2129\u20132200","journal-title":"Eur Heart J"},{"key":"9771_CR62","doi-asserted-by":"publisher","first-page":"g5630","DOI":"10.1136\/bmj.g5630","volume":"349","author":"MA Puhan","year":"2014","unstructured":"Puhan MA, Schunemann HJ, Murad MH, Li T, Brignardello-Petersen R, Singh JA, Kessels AG, Guyatt GH, for the GRADE Working Group (2014) A GRADE Working Group approach for rating the quality of treatment effect estimates from network meta-analysis. BMJ 349:g5630","journal-title":"BMJ"},{"key":"9771_CR63","doi-asserted-by":"publisher","first-page":"682","DOI":"10.1185\/03007998809111119","volume":"10","author":"F Ramsay","year":"1988","unstructured":"Ramsay F, Crawford RJ, Allman S, Bailey R, Martin A (1988) An open comparative study of two diuretic combinations, frusemide\/amiloride (\u2018Frumil\u2019) and bumetanide\/potassium chloride (\u2018Burinex\u2019 K), in the treatment of congestive cardiac failure in hospital out-patients. Curr Med Res Opin 10:682\u2013689","journal-title":"Curr Med Res Opin"},{"key":"9771_CR64","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1002\/jrsm.1037","volume":"3","author":"G Salanti","year":"2012","unstructured":"Salanti G (2012) Indirect and mixed-treatment comparison, network, or multiple-treatments meta-analysis: many names, many benefits, many concerns for the next generation evidence synthesis tool. Res Synth Methods 3:80\u201397","journal-title":"Res Synth Methods"},{"key":"9771_CR65","doi-asserted-by":"publisher","first-page":"857","DOI":"10.1016\/j.jclinepi.2008.10.001","volume":"62","author":"G Salanti","year":"2009","unstructured":"Salanti G, Marinho V, Higgins JP (2009) A case study of multiple-treatments meta-analysis demonstrates that covariates should be considered. J Clin Epidemiol 62:857\u2013864","journal-title":"J Clin Epidemiol"},{"key":"9771_CR66","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1016\/j.jclinepi.2010.03.016","volume":"64","author":"G Salanti","year":"2011","unstructured":"Salanti G, Ades AE, Ioannidis JP (2011) Graphical methods and numerical summaries for presenting results from multiple-treatment meta-analysis: an overview and tutorial. J Clin Epidemiol 64:163\u2013171","journal-title":"J Clin Epidemiol"},{"key":"9771_CR67","doi-asserted-by":"publisher","first-page":"e99682","DOI":"10.1371\/journal.pone.0099682","volume":"9","author":"G Salanti","year":"2014","unstructured":"Salanti G, Del Giovane C, Chaimani A et al (2014) Evaluating the quality of evidence from a network meta-analysis. PLoS One 9:e99682","journal-title":"PLoS One"},{"key":"9771_CR68","doi-asserted-by":"crossref","unstructured":"Sargento L, Simoes AV, Longo S et al (2016) Furosemide prescription during the dry state is a predictor of long-term survival of stable, optimally medicated patients with systolic heart failure. J Cardiovasc Pharmacol Ther","DOI":"10.1177\/1074248416675613"},{"key":"9771_CR69","doi-asserted-by":"publisher","first-page":"g7647","DOI":"10.1136\/bmj.g7647","volume":"349","author":"L Shamseer","year":"2015","unstructured":"Shamseer L, Moher D, Clarke M, Ghersi D, Liberati A, Petticrew M, Shekelle P, Stewart LA, the PRISMA-P Group (2015) Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation. BMJ 349:g7647","journal-title":"BMJ"},{"key":"9771_CR70","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1016\/S0140-6736(88)90347-9","volume":"1","author":"N Sharpe","year":"1988","unstructured":"Sharpe N, Murphy J, Smith H et al (1988) Treatment of patients with symptomless left ventricular dysfunction after myocardial infarction. Lancet (London, England) 1:255\u2013259","journal-title":"Lancet (London, England)"},{"key":"9771_CR71","doi-asserted-by":"publisher","first-page":"1277","DOI":"10.1136\/bmj.2.5473.1277","volume":"2","author":"JH Stewart","year":"1965","unstructured":"Stewart JH, Edwards KD (1965) Clinical comparison of frusemide with bendrofluazide, mersalyl, and ethacrynic acid. Br Med J 2:1277\u20131281","journal-title":"Br Med J"},{"issue":"1204\u20131213","key":"9771_CR72","first-page":"e1203","volume":"33","author":"Torafic Investigators Group","year":"2011","unstructured":"Torafic Investigators Group (2011) Effects of prolonged-release torasemide versus furosemide on myocardial fibrosis in hypertensive patients with chronic heart failure: a randomized, blinded-end point, active-controlled study. Clin Ther 33(1204\u20131213):e1203","journal-title":"Clin Ther"},{"key":"9771_CR73","doi-asserted-by":"publisher","first-page":"2252","DOI":"10.1016\/j.jacc.2004.09.009","volume":"44","author":"T Tsutamoto","year":"2004","unstructured":"Tsutamoto T, Sakai H, Wada A, Ishikawa C, Ohno K, Fujii M, Yamamoto T, Takayama T, Dohke T, Horie M (2004) Torasemide inhibits transcardiac extraction of aldosterone in patients with congestive heart failure. J Am Coll Cardiol 44:2252\u20132253","journal-title":"J Am Coll Cardiol"},{"key":"9771_CR74","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1016\/0014-2999(91)90812-5","volume":"205","author":"T Uchida","year":"1991","unstructured":"Uchida T, Yamanaga K, Nishikawa M, Ohtaki Y, Kido H, Watanabe M (1991) Anti-aldosteronergic effect of torasemide. Eur J Pharmacol 205:145\u2013150","journal-title":"Eur J Pharmacol"},{"key":"9771_CR75","doi-asserted-by":"publisher","first-page":"1599","DOI":"10.1001\/archinte.159.14.1599","volume":"159","author":"DJ Kraaij Van","year":"1999","unstructured":"Van Kraaij DJ, Jansen RW, Bouwels LH et al (1999) Furosemide withdrawal improves postprandial hypotension in elderly patients with heart failure and preserved left ventricular systolic function. Arch Intern Med 159:1599\u20131605","journal-title":"Arch Intern Med"},{"key":"9771_CR76","doi-asserted-by":"publisher","first-page":"601","DOI":"10.1016\/0009-9236(95)90222-8","volume":"57","author":"DL Vargo","year":"1995","unstructured":"Vargo DL, Kramer WG, Black PK, Smith WB, Serpas T, Brater DC (1995) Bioavailability, pharmacokinetics, and pharmacodynamics of torsemide and furosemide in patients with congestive heart failure. Clin Pharmacol Ther 57:601\u2013609","journal-title":"Clin Pharmacol Ther"},{"key":"9771_CR77","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/j.ejphar.2007.11.034","volume":"581","author":"PT Veeraveedu","year":"2008","unstructured":"Veeraveedu PT, Watanabe K, Ma M, Palaniyandi SS, Yamaguchi K\u2019, Suzuki K, Kodama M, Aizawa Y (2008) Torasemide, a long-acting loop diuretic, reduces the progression of myocarditis to dilated cardiomyopathy. Eur J Pharmacol 581:121\u2013131","journal-title":"Eur J Pharmacol"},{"key":"9771_CR78","doi-asserted-by":"publisher","first-page":"649","DOI":"10.1016\/j.bcp.2007.09.026","volume":"75","author":"PT Veeraveedu","year":"2008","unstructured":"Veeraveedu PT, Watanabe K, Ma M, Thandavarayan RA, Palaniyandi SS, Yamaguchi K\u2019, Suzuki K, Kodama M, Aizawa Y (2008) Comparative effects of torasemide and furosemide in rats with heart failure. Biochem Pharmacol 75:649\u2013659","journal-title":"Biochem Pharmacol"},{"key":"9771_CR79","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1002\/j.1552-4604.1982.tb02644.x","volume":"22","author":"A Vermeulen","year":"1982","unstructured":"Vermeulen A, Chadha DR (1982) Slow-release furosemide and hydrochlorothiazide in congestive cardiac failure: a controlled trial. J Clin Pharmacol 22:513\u2013519","journal-title":"J Clin Pharmacol"},{"key":"9771_CR80","doi-asserted-by":"crossref","unstructured":"Watanabe K, Sreedhar R, Thandavarayan RA et al (2016) Comparative effects of torasemide and furosemide on gap junction proteins and cardiac fibrosis in a rat model of dilated cardiomyopathy. Biofactors","DOI":"10.1002\/biof.1332"},{"key":"9771_CR81","doi-asserted-by":"publisher","first-page":"1794","DOI":"10.1016\/S0735-1097(99)00435-0","volume":"34","author":"AS Westheim","year":"1999","unstructured":"Westheim AS, Bostrom P, Christensen CC et al (1999) Hemodynamic and neuroendocrine effects for candoxatril and frusemide in mild stable chronic heart failure. J Am Coll Cardiol 34:1794\u20131801","journal-title":"J Am Coll Cardiol"},{"key":"9771_CR82","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1016\/0002-9343(81)90755-5","volume":"70","author":"JR Wilson","year":"1981","unstructured":"Wilson JR, Reichek N, Dunkman WB, Goldberg S (1981) Effect of diuresis on the performance of the failing left ventricle in man. Am J Med 70:234\u2013239","journal-title":"Am J Med"},{"key":"9771_CR83","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1253\/circj.67.384","volume":"67","author":"M Yamato","year":"2003","unstructured":"Yamato M, Sasaki T, Honda K, Fukuda M, Akutagawa O, Okamoto M, Hayashi T (2003) Effects of torasemide on left ventricular function and neurohumoral factors in patients with chronic heart failure. Circ J 67:384\u2013390","journal-title":"Circ J"}],"container-title":["Heart Failure Reviews"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10741-019-09771-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10741-019-09771-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10741-019-09771-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,3,13]],"date-time":"2020-03-13T00:30:23Z","timestamp":1584059423000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10741-019-09771-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3,14]]},"references-count":83,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,7]]}},"alternative-id":["9771"],"URL":"https:\/\/doi.org\/10.1007\/s10741-019-09771-8","relation":{},"ISSN":["1382-4147","1573-7322"],"issn-type":[{"value":"1382-4147","type":"print"},{"value":"1573-7322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,3,14]]},"assertion":[{"value":"14 March 2019","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Tobias T\u00e4ger has nothing to disclose. Hanna Fr\u00f6hlich has nothing to disclose. Mirjam Seiz has nothing to disclose. H.A. Katus has nothing to disclose. L. Frankenstein has nothing to disclose.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclosure"}}]}}