{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T15:10:12Z","timestamp":1790781012516,"version":"4.1.0"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2020,11,16]],"date-time":"2020-11-16T00:00:00Z","timestamp":1605484800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,11,16]],"date-time":"2020-11-16T00:00:00Z","timestamp":1605484800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Heart Fail Rev"],"published-print":{"date-parts":[[2021,3]]},"DOI":"10.1007\/s10741-020-10037-x","type":"journal-article","created":{"date-parts":[[2020,11,15]],"date-time":"2020-11-15T21:03:53Z","timestamp":1605474233000},"page":"363-369","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":68,"title":["Mechanisms of COVID-19-induced heart failure: a short review"],"prefix":"10.1007","volume":"26","author":[{"given":"Ernest A.","family":"Adeghate","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nabil","family":"Eid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaipaul","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,11,16]]},"reference":[{"key":"10037_CR1","doi-asserted-by":"publisher","unstructured":"Bostanciklioglu M (2020) Severe acute respiratory syndrome coronavirus 2 is penetrating to dementia research. Curr Neurovasc Res. https:\/\/doi.org\/10.2174\/1567202617666200522220509 (Online)","DOI":"10.2174\/1567202617666200522220509"},{"key":"10037_CR2","unstructured":"Worldometers.info (2020). COVID-19 Coronavirus pandemic. Dover, Delaware, USA. https:\/\/www.worldometers.info\/coronavirus\/?utm_campaign=homeAdvegas1?(Accessed 24 October, 2020)"},{"key":"10037_CR3","unstructured":"Centers for Disease Control (2020). Coronavirus Disease 2019 (COVID-19). https:\/\/covid.cdc.gov\/covid-data-tracker\/#cases_casesper100klast7days (Accessed 24 October 2020)"},{"key":"10037_CR4","doi-asserted-by":"publisher","unstructured":"G\u00fcemes-Villahoz N, Burgos-Blasco B, Vidal-Villegas B et al (2020) Novel insights into the transmission of SARS-CoV-2 through the ocular surface and its detection in tears and conjunctival secretions: a review. Adv Ther, 1\u201310. Advance online publication. https:\/\/doi.org\/10.1007\/s12325-020-01442-7","DOI":"10.1007\/s12325-020-01442-7"},{"key":"10037_CR5","doi-asserted-by":"publisher","unstructured":"Le Guennec L, Devianne J, Jalin L et al (2020) Orbitofrontal involvement in a neuroCOVID-19 patient. Epilepsia. Jun 26.https:\/\/doi.org\/10.1111\/epi.16612\n(Online)","DOI":"10.1111\/epi.16612"},{"issue":"9","key":"10037_CR6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.5501\/wjv.v9.i1.1","volume":"25","author":"R Kant","year":"2020","unstructured":"Kant R, Chandra L, Antony MA, Verma V (2020) Case of COVID-19 presenting with gastrointestinal symptoms. World J Virol 25(9):1\u20134. https:\/\/doi.org\/10.5501\/wjv.v9.i1.1","journal-title":"World J Virol"},{"key":"10037_CR7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s00134-020-06153-9","volume":"12","author":"P Gabarre","year":"2020","unstructured":"Gabarre P, Dumas G, Dupont T, Darmon M, Azoulay E, Zafrani L (2020) Acute kidney injury in critically ill patients with COVID-19. Intensive Care Med 12:1\u201310. https:\/\/doi.org\/10.1007\/s00134-020-06153-9","journal-title":"Intensive Care Med"},{"issue":"7","key":"10037_CR8","doi-asserted-by":"publisher","first-page":"1421","DOI":"10.1007\/s00277-020-04103-5","volume":"99","author":"X Liu","year":"2020","unstructured":"Liu X, Zhang R, He G (2020) Hematological findings in coronavirus disease 2019: indications of progression of disease. Ann Hematol 99(7):1421\u20131428. https:\/\/doi.org\/10.1007\/s00277-020-04103-5","journal-title":"Ann Hematol"},{"issue":"5","key":"10037_CR9","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1038\/s41569-020-0360-5","volume":"17","author":"YY Zheng","year":"2020","unstructured":"Zheng YY, Ma YT, Zhang JY, Xie X (2020) COVID-19 and the cardiovascular system. Nat Rev Cardiology 17(5):259\u2013260. https:\/\/doi.org\/10.1038\/s41569-020-0360-5","journal-title":"Nat Rev Cardiology"},{"key":"10037_CR10","doi-asserted-by":"publisher","first-page":"1068","DOI":"10.1016\/j.cjca.2020.05.018","volume":"16","author":"M Boukhris","year":"2020","unstructured":"Boukhris M, Hillani A, Moroni F et al (2020) Cardiovascular Implications of the COVID-19 pandemic: a global perspective. Can J Cardiol 16:1068\u20131080","journal-title":"Can J Cardiol"},{"key":"10037_CR11","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1084\/jem.20050828","volume":"202","author":"J Gu","year":"2005","unstructured":"Gu J, Gong E, Zhang B, Zheng J, Gao Z, Zhong Y et al (2005) Multiple organ infection and the pathogenesis of SARS. J Exp Med 202:415\u2013424","journal-title":"J Exp Med"},{"key":"10037_CR12","doi-asserted-by":"publisher","unstructured":"Nicholls JM, Poon LLM, Lee KC, Ng WF, Lai ST, Leung CY et al (2003) Lung pathology of fatal severe acute respiratory syndrome. Lancet 361:1773\u20131778. https:\/\/doi.org\/10.1016\/S0140-6736(03)13413-7","DOI":"10.1016\/S0140-6736(03)13413-7"},{"key":"10037_CR13","doi-asserted-by":"publisher","first-page":"911","DOI":"10.1002\/ejhf.1828","volume":"22","author":"G Tavazzi","year":"2020","unstructured":"Tavazzi G, Pellegrini C, Maurelli M (2020) Myocardial localization of coronavirus in COVID-19 cardiogenic shock. Eur J Heart Fail 22:911\u2013915","journal-title":"Eur J Heart Fail"},{"key":"10037_CR14","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1002\/ejhf.1828","volume":"395","author":"C Huang","year":"2020","unstructured":"Huang C, Wang Y, Li X (2020) Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 395:497\u2013506. https:\/\/doi.org\/10.1002\/ejhf.1828","journal-title":"Lancet"},{"key":"10037_CR15","doi-asserted-by":"publisher","unstructured":"Colling ME, Kanthi Y (2020) COVID-19-associated coagulopathy: an exploration of mechanisms. Vasc Med 25(5):471-478\u00a019:1358863X20932640.\u00a0https:\/\/doi.org\/10.1177\/1358863X20932640. PMID: 32558620; PMCID: PMC7306998\u00a0(Online)","DOI":"10.1177\/1358863X20932640"},{"issue":"4","key":"10037_CR16","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1161\/CIRCRESAHA.120.317447","volume":"127","author":"JD McFadyen","year":"2020","unstructured":"McFadyen JD, Stevens H, Peter K (2020) The emerging threat of micro thrombosis in COVID-19 and its therapeutic implications. Circ Res 127(4):571\u2013587. https:\/\/doi.org\/10.1161\/CIRCRESAHA.120.317447","journal-title":"Circ Res"},{"key":"10037_CR17","doi-asserted-by":"publisher","first-page":"1054","DOI":"10.1016\/S0140-6736(20)30566-3","volume":"395","author":"F Zhou","year":"2020","unstructured":"Zhou F, Yu T, Du R (2020) Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet 395:1054\u20131062","journal-title":"Lancet"},{"key":"10037_CR18","doi-asserted-by":"publisher","unstructured":"Chen T, Wu D, Chen H et al (2020) Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study. BMJ Mar 26;368:m1091.\u00a0https:\/\/doi.org\/10.1136\/bmj.m1091. Erratum in: BMJ. 2020 Mar 31;368:m1295. PMID: 32217556; PMCID: PMC7190011 (Online)","DOI":"10.1136\/bmj.m1091"},{"key":"10037_CR19","doi-asserted-by":"publisher","unstructured":"Chen XB, Du SH, Lu JC, Tan XH, Li DR, Yue X, Wang Q, Wang HJ, Qiao DF (2020) Retrospective analysis of 61 cases of children died of viral pneumonia. Fa Yi Xue Za Zhi 36:164\u2013168. English, Chinese. https:\/\/doi.org\/10.12116\/j.issn.1004-5619.2020.02.003","DOI":"10.12116\/j.issn.1004-5619.2020.02.003"},{"key":"10037_CR20","doi-asserted-by":"publisher","unstructured":"Bavishi C, Bonow RO, Trivedi V, Abbott JD, Messerli FH, Bhatt DL (2020) Acute myocardial injury in patients hospitalized with COVID-19 infection: a review. Prog Cardiovasc Dis Jun 5:S0033\u20130620(20)30123\u20137.\u00a0https:\/\/doi.org\/10.1016\/j.pcad.2020.05.013 (Online)","DOI":"10.1016\/j.pcad.2020.05.013"},{"key":"10037_CR21","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/pin.12868","volume":"70","author":"K Imanaka-Yoshida","year":"2020","unstructured":"Imanaka-Yoshida K (2020) Inflammation in myocardial disease: From myocarditis to dilated cardiomyopathy. Pathol Int 70:1\u201311. https:\/\/doi.org\/10.1111\/pin.12868","journal-title":"Pathol Int"},{"key":"10037_CR22","first-page":"164","volume":"29","author":"HF Xu","year":"2013","unstructured":"Xu HF, Meng L, Yao J, Gu ZY, Liu GQ, Shen YW, Zhao ZQ (2013) Myocardial expression of Spry1 and MAPK proteins of viral myocarditis. Fa Yi Xue Za Zhi 29:164\u2013167","journal-title":"Fa Yi Xue Za Zhi"},{"key":"10037_CR23","doi-asserted-by":"publisher","unstructured":"Ka\u017eukauskien\u0117 I, Baltr\u016bnien\u0117 V, Jakubauskas A et al (2020) Prevalence and prognostic relevance of myocardial inflammation and cardiotropic viruses in non-ischemic dilated cardiomyopathy. Cardiol J Jun 22. https:\/\/doi.org\/10.5603\/CJ.a2020.0088\n(Online)","DOI":"10.5603\/CJ.a2020.0088"},{"issue":"10","key":"10037_CR24","doi-asserted-by":"publisher","first-page":"1443","DOI":"10.1161\/CIRCRESAHA.120.317055","volume":"126","author":"A Akhmerov","year":"2020","unstructured":"Akhmerov A, Marb\u00e1n E (2020) COVID-19 and the heart. Circ Res 126(10):1443\u20131455","journal-title":"Circ Res"},{"key":"10037_CR25","doi-asserted-by":"publisher","unstructured":"Guzik TJ, Mohiddin SA, Dimarco A et al (2020) COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options. Cardiovasc Res Apr 30:116(10):1666-1687 cvaa106.\u00a0https:\/\/doi.org\/10.1093\/cvr\/cvaa106\n(Online)","DOI":"10.1093\/cvr\/cvaa106"},{"key":"10037_CR26","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1089\/jir.2008.0027","volume":"29","author":"SL Deshmane","year":"2009","unstructured":"Deshmane SL, Kremlev S, Amini S, Sawaya BE (2009) Monocyte chemoattractant protein-1 (MCP-1): an overview. J Interferon Cytokine Res 29:313\u2013326. https:\/\/doi.org\/10.1089\/jir.2008.0027","journal-title":"J Interferon Cytokine Res"},{"key":"10037_CR27","doi-asserted-by":"publisher","unstructured":"Chen P, Zhao Y, Gao H, Huang J, Lu Y, Song J, Lin L, Lin Z, Ou C, Sun H, Li Y, Zeng C, Cooper DKC, Zhan Y, Deng X, Mou L (2019) Selective inhibition of cyclooxygenase-2 protects porcine aortic endothelial cells from human antibody-mediated complement-dependent cytotoxicity. Xenotransplantation 26(6):e12536. https:\/\/doi.org\/10.1111\/xen.12536 (Online)","DOI":"10.1111\/xen.12536"},{"issue":"11","key":"10037_CR28","doi-asserted-by":"publisher","first-page":"2494","DOI":"10.1097\/j.pain.0000000000002051","volume":"161","author":"S Shiers","year":"2020","unstructured":"Shiers S, Ray PR, Wangzhou A et al (2020) ACE2 and SCARF expression in human DRG nociceptors: implications for SARS-CoV-2 virus neurological effects. Pain.161(11):2494-2501 https:\/\/doi.org\/10.1097\/j.pain.0000000000002051","journal-title":"Pain."},{"key":"10037_CR29","doi-asserted-by":"publisher","unstructured":"Chen H, Wang C, Li J, Huandike M, Liu J, Huang Q, Li X, Zhang H, Zhou J, Chai L (2020) Chinese herbal formula, Huayu Tongbi Fang, Attenuates inflammatory proliferation of rat synoviocytes induced by IL-1\u03b2 by regulating proliferation and differentiation of T lymphocytes. Evid Based Complement Alternat Med 2020:1706837. https:\/\/doi.org\/10.1155\/2020\/1706837 (Online)","DOI":"10.1155\/2020\/1706837"},{"issue":"1","key":"10037_CR30","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1016\/j.yjmcc.2009.12.013","volume":"49","author":"Y Chen","year":"2010","unstructured":"Chen Y, Pat B, Zheng J (2010) Tumor necrosis factor-alpha produced in cardiomyocytes mediates a predominant myocardial inflammatory response to stretch in early volume overload. J Mol Cell Cardiol 49(1):70\u201378","journal-title":"J Mol Cell Cardiol"},{"issue":"10","key":"10037_CR31","doi-asserted-by":"publisher","first-page":"4220","DOI":"10.1073\/pnas.88.10.4220","volume":"88","author":"LJ Walsh","year":"1991","unstructured":"Walsh LJ, Trinchieri G, Waldorf HA, Whitaker D, Murphy GF (1991) Human dermal mast cells contain and release tumor necrosis factor alpha, which induces endothelial leukocyte adhesion molecule 1. Proc Natl Acad Sci USA 88(10):4220\u20134224. https:\/\/doi.org\/10.1073\/pnas.88.10.4220","journal-title":"Proc Natl Acad Sci USA"},{"key":"10037_CR32","doi-asserted-by":"publisher","unstructured":"Tuyen TT, Viet NT, Hang NT et al (2020) Pro-inflammatory cytokines are modulated in Vietnamese patients with dengue fever. Viral Immunol. May 22.\u00a033(7):514-520\u00a0https:\/\/doi.org\/10.1089\/vim.2020.0023","DOI":"10.1089\/vim.2020.0023"},{"key":"10037_CR33","doi-asserted-by":"publisher","unstructured":"Harikrishnan S, Mohanan PP, Chopra VK et al (2020) Cardiological society of India position statement on COVID-19 and heart failure. Version 2. Indian Heart J. 2020;72(2):75\u201381.https:\/\/doi.org\/10.1016\/j.ihj.2020.04.012","DOI":"10.1016\/j.ihj.2020.04.012"},{"key":"10037_CR34","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s40290-020-00342-z","volume":"13","author":"S Atal","year":"2020","unstructured":"Atal S, Fatima Z (2020) IL-6 inhibitors in the treatment of serious COVID-19: a promising therapy? Pharmaceut Med 13:1\u20139. https:\/\/doi.org\/10.1007\/s40290-020-00342-z","journal-title":"Pharmaceut Med"},{"issue":"3","key":"10037_CR35","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1007\/s00428-020-02881-x","volume":"477","author":"H B\u00f6sm\u00fcller","year":"2020","unstructured":"B\u00f6sm\u00fcller H, Traxler S, Bitzer M, H\u00e4berle H, Raiser W, Nann D, Frauenfeld L, Vogelsberg A, Klingel K, Fend F (2020) The evolution of pulmonary pathology in fatal COVID-19 disease: an autopsy study with clinical correlation. Virchows Arch 477(3):349\u2013357.https:\/\/doi.org\/10.1007\/s00428-020-02881-x","journal-title":"Virchows Arch"},{"issue":"7","key":"10037_CR36","doi-asserted-by":"publisher","first-page":"1652","DOI":"10.3390\/cells90716521","volume":"9","author":"R Amraei","year":"2020","unstructured":"Amraei R, Rahimi N (2020) COVID-19. Renin-angiotensin system and endothelial dysfunction. Cells 9(7):1652. https:\/\/doi.org\/10.3390\/cells90716521","journal-title":"Renin-angiotensin system and endothelial dysfunction. Cells"},{"key":"10037_CR37","doi-asserted-by":"publisher","unstructured":"Papamichalis P, Papadogoulas A, Katsiafylloudis P et al (2020) Combination of thrombolytic and immunosuppressive therapy for coronavirus disease 2019: a case report. Int J Infect Dis 97:90\u201393.\u00a0\u00a0hhttps:\/\/doi.org\/10.1016\/j.ijid.2020.05.118. Epub ahead of print. PMID: 32497796; PMCID: PMC7263262","DOI":"10.1016\/j.ijid.2020.05.118"},{"key":"10037_CR38","doi-asserted-by":"publisher","unstructured":"Mikami T, Miyashita H, Yamada T et al (2020) Risk factors for mortality in patients with COVID-19 in New York City. J Gen Intern Med. Jun 30. https:\/\/doi.org\/10.1007\/s11606-020-05983-z. Epub ahead of print. PMID: 32607928 (Online)","DOI":"10.1007\/s11606-020-05983-z"},{"key":"10037_CR39","doi-asserted-by":"publisher","first-page":"1733","DOI":"10.1161\/CIRCULATIONAHA.120.047008","volume":"141","author":"AR Chapman","year":"2020","unstructured":"Chapman AR, Bularga A, Mills NL (2020) High-sensitivity cardiac troponin can be an ally in the fight against COVID-19. Circulation 141:1733\u20131735. https:\/\/doi.org\/10.1161\/CIRCULATIONAHA.120.047008","journal-title":"Circulation"},{"key":"10037_CR40","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1023\/b:mcbi.0000028755.86521.11","volume":"261","author":"E Adeghate","year":"2004","unstructured":"Adeghate E (2004) Molecular and cellular basis of the aetiology and management of diabetic cardiomyopathy: a short review. Mol Cell Biochem 261:187\u2013191. https:\/\/doi.org\/10.1023\/b:mcbi.0000028755.86521.11","journal-title":"Mol Cell Biochem"},{"key":"10037_CR41","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1007\/s10741-013-9388-5","volume":"19","author":"E Adeghate","year":"2014","unstructured":"Adeghate E, Singh J (2014) Structural changes in the myocardium during diabetes-induced cardiomyopathy. Heart Fail Rev 19:15\u201323. https:\/\/doi.org\/10.1007\/s10741-013-9388-5","journal-title":"Heart Fail Rev"},{"key":"10037_CR42","doi-asserted-by":"publisher","unstructured":"Shi S, Qin M, Shen B et al (2020) Association of cardiac injury with mortality in hospitalized patients with COVID-19 in Wuhan, China. JAMA Cardiol. Mar 25:e200950. https:\/\/doi.org\/10.1001\/jamacardio.2020.0950\n(Online)","DOI":"10.1001\/jamacardio.2020.0950"}],"container-title":["Heart Failure Reviews"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10741-020-10037-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10741-020-10037-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10741-020-10037-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,2,20]],"date-time":"2021-02-20T13:00:05Z","timestamp":1613826005000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10741-020-10037-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,16]]},"references-count":42,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["10037"],"URL":"https:\/\/doi.org\/10.1007\/s10741-020-10037-x","relation":{},"ISSN":["1382-4147","1573-7322"],"issn-type":[{"value":"1382-4147","type":"print"},{"value":"1573-7322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,11,16]]},"assertion":[{"value":"5 October 2020","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 November 2020","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}