{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T21:20:53Z","timestamp":1776115253781,"version":"3.50.1"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2021,11,19]],"date-time":"2021-11-19T00:00:00Z","timestamp":1637280000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,11,19]],"date-time":"2021-11-19T00:00:00Z","timestamp":1637280000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Heart Fail Rev"],"published-print":{"date-parts":[[2022,9]]},"DOI":"10.1007\/s10741-021-10196-5","type":"journal-article","created":{"date-parts":[[2021,11,19]],"date-time":"2021-11-19T17:02:26Z","timestamp":1637341346000},"page":"1829-1836","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["New onset nonischemic cardiomyopathy post liver transplantation"],"prefix":"10.1007","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5746-3135","authenticated-orcid":false,"given":"Maya","family":"Guglin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kutaiba","family":"Nazif","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,11,19]]},"reference":[{"key":"10196_CR1","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1016\/j.cardfail.2018.10.013","volume":"25","author":"VA Eyvazian","year":"2019","unstructured":"Eyvazian VA, Gordin JS, Yang EH, Aksoy O, Honda HM, Busuttil RW et al (2019) Incidence, predictors, and outcomes of new-onset left ventricular systolic dysfunction after orthotopic liver transplantation. J Cardiac Fail 25:166\u2013172","journal-title":"J Cardiac Fail"},{"key":"10196_CR2","doi-asserted-by":"publisher","first-page":"1950","DOI":"10.1016\/j.transproceed.2019.04.063","volume":"51","author":"AE Sakr","year":"2019","unstructured":"Sakr AE, Fraser GE, Doctorian TP, Kim HB, Narasimha D, Abudayyeh I et al (2019) Predictors of systolic heart failure and mortality following orthotopic liver transplantation: a single-center cohort. Transpl Proc 51:1950\u20131955","journal-title":"Transpl Proc"},{"key":"10196_CR3","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1038\/nrgastro.2013.210","volume":"11","author":"S Wiese","year":"2014","unstructured":"Wiese S, Hove JD, Bendtsen F, M\u00f8ller S (2014) Cirrhotic cardiomyopathy: pathogenesis and clinical relevance. Nat Rev Gastroenterol Hepatol 11:177\u2013186","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"10196_CR4","doi-asserted-by":"publisher","first-page":"2019","DOI":"10.1002\/hep.29104","volume":"65","author":"R Yotti","year":"2017","unstructured":"Yotti R, Ripoll C, Benito Y, Catalina MV, Elizaga J, Rincon D et al (2017) Left ventricular systolic function is associated with sympathetic nervous activity and markers of inflammation in cirrhosis. Hepatology (Baltimore, MD) 65:2019\u20132030","journal-title":"Hepatology (Baltimore, MD)"},{"key":"10196_CR5","doi-asserted-by":"publisher","first-page":"701","DOI":"10.1002\/lt.23654","volume":"19","author":"W Qureshi","year":"2013","unstructured":"Qureshi W, Mittal C, Ahmad U, Alirhayim Z, Hassan S, Qureshi S et al (2013) Clinical predictors of post-liver transplant new-onset heart failure. Liver transplantation\u202f: official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 19:701\u2013710","journal-title":"Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society"},{"key":"10196_CR6","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1002\/lt.24846","volume":"24","author":"C Jansen","year":"2018","unstructured":"Jansen C, Cox A, Schueler R, Schneider M, Lehmann J, Praktiknjo M et al (2018) Increased myocardial contractility identifies patients with decompensated cirrhosis requiring liver transplantation. Liver transplantation\u202f: official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 24:15\u201325","journal-title":"Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society"},{"key":"10196_CR7","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1213\/00000539-198502000-00003","volume":"64","author":"FJ Carmichael","year":"1985","unstructured":"Carmichael FJ, Lindop MJ, Farman JV (1985) Anesthesia for hepatic transplantation: cardiovascular and metabolic alterations and their management. Anesth Analg 64:108\u2013116","journal-title":"Anesth Analg"},{"key":"10196_CR8","doi-asserted-by":"crossref","unstructured":"Bezinover D, Mukhtar A, Wagener G, Wray C, Blasi A, Kronish K et al (2021) Hemodynamic instability during liver transplantation in patients with end-stage liver disease: a consensus document from ILTS, LICAGE, and SATA. Transplantation","DOI":"10.1097\/TP.0000000000003642"},{"key":"10196_CR9","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1016\/0883-9441(93)90021-C","volume":"8","author":"S Aggarwal","year":"1993","unstructured":"Aggarwal S, Kang Y, Freeman JA, Fortunato FL Jr, Pinsky MR (1993) Postreperfusion syndrome: hypotension after reperfusion of the transplanted liver. J Crit Care 8:154\u2013160","journal-title":"J Crit Care"},{"key":"10196_CR10","doi-asserted-by":"publisher","first-page":"1204","DOI":"10.1111\/echo.14037","volume":"35","author":"L Vetrugno","year":"2018","unstructured":"Vetrugno L, Barnariol F, Bignami E, Centonze GD, De Flaviis A, Piccioni F et al (2018) Transesophageal ultrasonography during orthotopic liver transplantation: show me more. Echocardiography 35:1204\u20131215","journal-title":"Echocardiography"},{"key":"10196_CR11","doi-asserted-by":"publisher","first-page":"1815","DOI":"10.1053\/j.jvca.2018.02.033","volume":"32","author":"AA Dalia","year":"2018","unstructured":"Dalia AA, Flores A, Chitilian H, Fitzsimons MG (2018) A comprehensive review of transesophageal echocardiography during orthotopic liver transplantation. J Cardiothorac Vasc Anesth 32:1815\u20131824","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"10196_CR12","doi-asserted-by":"publisher","first-page":"26","DOI":"10.12659\/AOT.881861","volume":"16","author":"B Bukowicka","year":"2011","unstructured":"Bukowicka B, Akar RA, Olszewska A, Smoter P, Krawczyk M (2011) The occurrence of postreperfusion syndrome in orthotopic liver transplantation and its significance in terms of complications and short-term survival. Ann Transplant 16:26\u201330","journal-title":"Ann Transplant"},{"key":"10196_CR13","doi-asserted-by":"publisher","first-page":"1430","DOI":"10.1002\/lt.23511","volume":"18","author":"HG Ryu","year":"2012","unstructured":"Ryu HG, Jung CW, Lee HC, Cho YJ (2012) Epinephrine and phenylephrine pretreatments for preventing postreperfusion syndrome during adult liver transplantation. Liver transplantation\u202f: official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 18:1430\u20131439","journal-title":"Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society"},{"key":"10196_CR14","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/j.jacc.2011.03.026","volume":"58","author":"Z Raval","year":"2011","unstructured":"Raval Z, Harinstein ME, Skaro AI, Erdogan A, DeWolf AM, Shah SJ et al (2011) Cardiovascular risk assessment of the liver transplant candidate. J Am Coll Cardiol 58:223\u2013231","journal-title":"J Am Coll Cardiol"},{"key":"10196_CR15","doi-asserted-by":"crossref","unstructured":"El Hadi H, Di Vincenzo A, Vettor R, Rossato M (2020) Relationship between heart disease and liver disease: a two-way street. Cells 9","DOI":"10.3390\/cells9030567"},{"key":"10196_CR16","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1002\/hep.510270106","volume":"27","author":"M Bernardi","year":"1998","unstructured":"Bernardi M, Calandra S, Colantoni A, Trevisani F, Raimondo ML, Sica G et al (1998) Q-T interval prolongation in cirrhosis: prevalence, relationship with severity, and etiology of the disease and possible pathogenetic factors. Hepatology (Baltimore, MD) 27:28\u201334","journal-title":"Hepatology (Baltimore, MD)"},{"key":"10196_CR17","doi-asserted-by":"crossref","unstructured":"Genovesi S, Prata Pizzala DM, Pozzi M, Ratti L, Milanese M, Pieruzzi F et al (2009) QT interval prolongation and decreased heart rate variability in cirrhotic patients: relevance of hepatic venous pressure gradient and serum calcium. Clinical science (London, England : 1979) 116:851\u20139","DOI":"10.1042\/CS20080325"},{"key":"10196_CR18","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1177\/0003319707300368","volume":"58","author":"F Kosar","year":"2007","unstructured":"Kosar F, Ates F, Sahin I, Karincaoglu M, Yildirim B (2007) QT interval analysis in patients with chronic liver disease: a prospective study. Angiology 58:218\u2013224","journal-title":"Angiology"},{"key":"10196_CR19","first-page":"463","volume":"9","author":"GW Dec","year":"1995","unstructured":"Dec GW, Kondo N, Farrell ML, Dienstag J, Cosimi AB, Semigran MJ (1995) Cardiovascular complications following liver transplantation. Clin Transplant 9:463\u2013471","journal-title":"Clin Transplant"},{"key":"10196_CR20","first-page":"185","volume":"5","author":"XY Shi","year":"2006","unstructured":"Shi XY, Xu ZD, Xu HT, Jiang JJ, Liu G (2006) Cardiac arrest after graft reperfusion during liver transplantation. Hepatobiliary Pancreat Dis Int 5:185\u2013189","journal-title":"Hepatobiliary Pancreat Dis Int"},{"key":"10196_CR21","doi-asserted-by":"crossref","unstructured":"Aniskevich S, Chadha RM, Peiris P, Taner CB, Torp KL, Thomas CS et al (2017) Intra-operative predictors of postoperative Takotsubo syndrome in liver transplant recipients-an exploratory case-control study. Clinical trans 31","DOI":"10.1111\/ctr.13092"},{"key":"10196_CR22","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1016\/j.transproceed.2017.11.017","volume":"50","author":"AA Vitin","year":"2018","unstructured":"Vitin AA, Pennington MW, Bowdle TA, Rayhill SC, Sibulesky L, Reyes JD et al (2018) Stress (Takotsubo) cardiomyopathy during liver transplantation: case study and literature review. Transpl Proc 50:211\u2013216","journal-title":"Transpl Proc"},{"key":"10196_CR23","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1177\/1089253216652223","volume":"20","author":"S Kim","year":"2016","unstructured":"Kim S, DeMaria S Jr, Cohen E, Silvay G, Zerillo J (2016) Prolonged intraoperative cardiac resuscitation complicated by intracardiac thrombus in a patient undergoing orthotopic liver transplantation. Semin Cardiothorac Vasc Anesth 20:246\u2013251","journal-title":"Semin Cardiothorac Vasc Anesth"},{"key":"10196_CR24","doi-asserted-by":"publisher","first-page":"442","DOI":"10.1053\/j.jvca.2007.11.015","volume":"22","author":"AK Tiwari","year":"2008","unstructured":"Tiwari AK, D\u2019Attellis N (2008) Intraoperative left ventricular apical ballooning: transient Takotsubo cardiomyopathy during orthotopic liver transplantation. J Cardiothorac Vasc Anesth 22:442\u2013445","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"10196_CR25","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1053\/j.jvca.2009.07.021","volume":"24","author":"SS Eagle","year":"2010","unstructured":"Eagle SS, Thompson A, Fong PP, Pretorius M, Deegan RJ, Hairr JW et al (2010) Takotsubo cardiomyopathy and coronary vasospasm during orthotopic liver transplantation: separate entities or common mechanism? J Cardiothorac Vasc Anesth 24:629\u2013632","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"10196_CR26","doi-asserted-by":"publisher","first-page":"2497","DOI":"10.1016\/j.transproceed.2012.07.037","volume":"44","author":"LJ Tachotti Pires","year":"2012","unstructured":"Tachotti Pires LJ, Cardoso Curiati MN, Vissoci Reiche F, Silvestre OM, Mangini S, Carballo Afonso R et al (2012) Stress-induced cardiomyopathy (takotsubo cardiomyopathy) after liver transplantation-report of two cases. Transpl Proc 44:2497\u20132500","journal-title":"Transpl Proc"},{"key":"10196_CR27","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1053\/j.jvca.2016.04.030","volume":"31","author":"S Elapavaluru","year":"2017","unstructured":"Elapavaluru S, Gologorsky A, Thai N, Uemura T, Khalil R, Mareddy C et al (2017) Perioperative stress cardiomyopathy in simultaneous liver and kidney transplantation: a call for early consideration of mechanical circulatory support. J Cardiothorac Vasc Anesth 31:248\u2013253","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"10196_CR28","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1186\/s12871-018-0560-2","volume":"18","author":"S Sharma","year":"2018","unstructured":"Sharma S, Karamchandani K, Wilson R, Baskin S, Bezinover D (2018) Acute heart failure after orthotopic liver transplantation: a case series from one center. BMC Anesthesiol 18:102","journal-title":"BMC Anesthesiol"},{"key":"10196_CR29","doi-asserted-by":"publisher","first-page":"594","DOI":"10.1093\/bja\/aeu029","volume":"112","author":"R Harika","year":"2014","unstructured":"Harika R, Bermas K, Hughes C, Al-Khafaji A, Iyer M, Wallace DJ (2014) Cardiac arrest after liver transplantation in a patient with takotsubo cardiomyopathy. Br J Anaesth 112:594\u2013595","journal-title":"Br J Anaesth"},{"key":"10196_CR30","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1002\/lt.500040513","volume":"4","author":"P Sampathkumar","year":"1998","unstructured":"Sampathkumar P, Lerman A, Kim BY, Narr BJ, Poterucha JJ, Torsher LC et al (1998) Post-liver transplantation myocardial dysfunction. Liver Transpl Surg 4:399\u2013403","journal-title":"Liver Transpl Surg"},{"key":"10196_CR31","doi-asserted-by":"publisher","first-page":"e105","DOI":"10.1111\/liv.12501","volume":"34","author":"ML Yataco","year":"2014","unstructured":"Yataco ML, Difato T, Bargehr J, Rosser BG, Patel T, Trejo-Gutierrez JF et al (2014) Reversible non-ischaemic cardiomyopathy and left ventricular dysfunction after liver transplantation: a single-centre experience. Liver Int 34:e105\u2013e110","journal-title":"Liver Int"},{"key":"10196_CR32","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1016\/j.amjcard.2007.08.056","volume":"101","author":"MJ Eimer","year":"2008","unstructured":"Eimer MJ, Wright JM, Wang EC, Kulik L, Blei A, Flamm S et al (2008) Frequency and significance of acute heart failure following liver transplantation. Am J Cardiol 101:242\u2013244","journal-title":"Am J Cardiol"},{"key":"10196_CR33","doi-asserted-by":"publisher","first-page":"873","DOI":"10.1097\/TP.0000000000000387","volume":"99","author":"MS Mandell","year":"2015","unstructured":"Mandell MS, Seres T, Lindenfeld J, Biggins SW, Chascsa D, Ahlgren B et al (2015) Risk factors associated with acute heart failure during liver transplant surgery: a case control study. Transplantation 99:873\u2013878","journal-title":"Transplantation"},{"key":"10196_CR34","doi-asserted-by":"crossref","unstructured":"Sonny A, Govindarajan SR, Jaber WA, Cywinski JB (2018) Systolic heart failure after liver transplantation: incidence, predictors, and outcome. Clinical trans\u00a032:e13199","DOI":"10.1111\/ctr.13199"},{"key":"10196_CR35","doi-asserted-by":"publisher","first-page":"1296","DOI":"10.1002\/lt.21822","volume":"15","author":"F Schnell","year":"2009","unstructured":"Schnell F, Donal E, Lorho R, Lavoue S, Gacouin A, Compagnon P et al (2009) Severe left-sided heart failure early after liver transplantation. Liver transplantation\u202f: official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 15:1296\u20131305","journal-title":"Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society"},{"key":"10196_CR36","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1056\/NEJMoa043046","volume":"352","author":"IS Wittstein","year":"2005","unstructured":"Wittstein IS, Thiemann DR, Lima JA, Baughman KL, Schulman SP, Gerstenblith G et al (2005) Neurohumoral features of myocardial stunning due to sudden emotional stress. N Engl J Med 352:539\u2013548","journal-title":"N Engl J Med"},{"key":"10196_CR37","doi-asserted-by":"publisher","first-page":"342","DOI":"10.1002\/ccd.21338","volume":"71","author":"P Angelini","year":"2008","unstructured":"Angelini P (2008) Transient left ventricular apical ballooning: a unifying pathophysiologic theory at the edge of Prinzmetal angina. Catheterization and cardiovascular interventions\u202f: official journal of the Society for Cardiac Angiography & Interventions 71:342\u2013352","journal-title":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions"},{"key":"10196_CR38","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1016\/j.nuclcard.2008.02.032","volume":"15","author":"C Burgdorf","year":"2008","unstructured":"Burgdorf C, Bonnemeier H, von Hof K, Schunkert H, Kurowski V (2008) Coronary artery vasospasm or true transient left ventricular apical ballooning? Differentiation by nuclear imaging. Journal of nuclear cardiology\u202f: official publication of the American Society of Nuclear Cardiology 15:599\u2013603","journal-title":"Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology"},{"key":"10196_CR39","doi-asserted-by":"publisher","first-page":"408","DOI":"10.1016\/j.ahj.2007.11.008","volume":"155","author":"A Prasad","year":"2008","unstructured":"Prasad A, Lerman A, Rihal CS (2008) Apical ballooning syndrome (Tako-Tsubo or stress cardiomyopathy): a mimic of acute myocardial infarction. Am Heart J 155:408\u2013417","journal-title":"Am Heart J"},{"key":"10196_CR40","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1016\/j.jhep.2019.10.002","volume":"72","author":"V Giannelli","year":"2020","unstructured":"Giannelli V, Roux O, Laou\u00e9nan C, Manchon P, Ausloos F, Bachelet D et al (2020) Impact of cardiac function, refractory ascites and beta blockers on the outcome of patients with cirrhosis listed for liver transplantation. J Hepatol 72:463\u2013471","journal-title":"J Hepatol"},{"key":"10196_CR41","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1053\/j.jvca.2013.10.011","volume":"28","author":"W Soong","year":"2014","unstructured":"Soong W, Sherwani SS, Ault ML, Baudo AM, Herborn JC, De Wolf AM (2014) United States practice patterns in the use of transesophageal echocardiography during adult liver transplantation. J Cardiothorac Vasc Anesth 28:635\u2013639","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"10196_CR42","doi-asserted-by":"crossref","unstructured":"Hofer RE, Vogt MNP, Taner T, Findlay JY (2020) Influence of intraoperative transesophageal echocardiography and pulmonary artery catheter monitoring on outcomes in liver transplantation. Transplant Direct. 6:e525","DOI":"10.1097\/TXD.0000000000000972"},{"key":"10196_CR43","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1053\/j.jvca.2015.09.009","volume":"30","author":"SK Shillcutt","year":"2016","unstructured":"Shillcutt SK, Ringenberg KJ, Chacon MM, Brakke TR, Montzingo CR, Lyden ER et al (2016) Liver transplantation: intraoperative transesophageal echocardiography findings and relationship to major postoperative adverse cardiac events. J Cardiothorac Vasc Anesth 30:107\u2013114","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"10196_CR44","first-page":"306","volume":"58","author":"G de la Morena","year":"1994","unstructured":"de la Morena G, Acosta F, Villegas M, Bento M, Sansano T, Bueno FS et al (1994) Ventricular function during liver reperfusion in hepatic transplantation. A transesophageal echocardiographic study Transplantation 58:306\u2013310","journal-title":"A transesophageal echocardiographic study Transplantation"}],"container-title":["Heart Failure Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10741-021-10196-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10741-021-10196-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10741-021-10196-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,18]],"date-time":"2022-08-18T07:30:08Z","timestamp":1660807808000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10741-021-10196-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,19]]},"references-count":44,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["10196"],"URL":"https:\/\/doi.org\/10.1007\/s10741-021-10196-5","relation":{},"ISSN":["1382-4147","1573-7322"],"issn-type":[{"value":"1382-4147","type":"print"},{"value":"1573-7322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,19]]},"assertion":[{"value":"11 November 2021","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 November 2021","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}