{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,6,7]],"date-time":"2024-06-07T02:53:47Z","timestamp":1717728827765},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2013,4,13]],"date-time":"2013-04-13T00:00:00Z","timestamp":1365811200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Inflammation"],"published-print":{"date-parts":[[2013,10]]},"DOI":"10.1007\/s10753-013-9636-9","type":"journal-article","created":{"date-parts":[[2013,4,12]],"date-time":"2013-04-12T11:50:37Z","timestamp":1365767437000},"page":"1041-1054","source":"Crossref","is-referenced-by-count":8,"title":["RNA Interference Targeting p110\u03b2 Reduces Tumor Necrosis Factor-Alpha Production in Cellular Response to Wear Particles In vitro and Osteolysis In vivo"],"prefix":"10.1007","volume":"36","author":[{"given":"Jian-bin","family":"Huang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yue","family":"Ding","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong-sheng","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei-ke","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhi-ping","family":"Guan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mao-lin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2013,4,13]]},"reference":[{"issue":"5","key":"9636_CR1","doi-asserted-by":"crossref","first-page":"765","DOI":"10.2106\/00004623-199173050-00016","volume":"73","author":"I Wiklund","year":"1991","unstructured":"Wiklund, I., and B. Romanus. 1991. A comparison of quality of life before and after arthroplasty in patients who had arthrosis of the hip joint. The Journal of Bone and Joint Surgery American Volume 73(5): 765\u2013769.","journal-title":"The Journal of Bone and Joint Surgery American Volume"},{"key":"9636_CR2","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1097\/00003086-199203000-00003","volume":"276","author":"HC Amstutz","year":"1992","unstructured":"Amstutz, H.C., P. Campbell, N. Kossovsky, and I.C. Clarke. 1992. Mechanism and clinical significance of wear debris-induced osteolysis. Clinical Orthopaedics and Related Research 276: 7\u201318.","journal-title":"Clinical Orthopaedics and Related Research"},{"key":"9636_CR3","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1097\/00003086-197509000-00014","volume":"111","author":"J Charnley","year":"1975","unstructured":"Charnley, J. 1975. Fracture of femoral prostheses in total hip replacement. A clinical study. Clinical Orthopaedics and Related Research 111: 105\u2013120.","journal-title":"Clinical Orthopaedics and Related Research"},{"issue":"3","key":"9636_CR4","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1002\/jbm.1264","volume":"59","author":"T Akisue","year":"2002","unstructured":"Akisue, T., T.W. Bauer, C.F. Farver, and Y. Mochida. 2002. The effect of particle wear debris on NFkappaB activation and pro-inflammatory cytokine release in differentiated THP-1 cells. Journal of Biomedical Materials Research 59(3): 507\u2013515.","journal-title":"Journal of Biomedical Materials Research"},{"issue":"7","key":"9636_CR5","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1111\/j.1525-1594.2010.01175.x","volume":"35","author":"CQ Qin","year":"2011","unstructured":"Qin, C.Q., Y. Ding, D.S. Huang, J. Xu, R.F. Ma, and J.B. Huang. 2011. Down-regulation of TNF-alpha by small interfering RNA inhibits particle-induced inflammation in vitro. Artificial Organs 35(7): 706\u2013714.","journal-title":"Artificial Organs"},{"key":"9636_CR6","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1097\/01.blo.0000150311.33227.b1","volume":"433","author":"SP Zysk","year":"2005","unstructured":"Zysk, S.P., H.H. Gebhard, T. Kalteis, M. Schmitt-Sody, V. Jansson, K. Messmer, and A. Veihelmann. 2005. Particles of all sizes provoke inflammatory responses in vivo. Clinical Orthopaedics and Related Research 433: 258\u2013264.","journal-title":"Clinical Orthopaedics and Related Research"},{"issue":"1","key":"9636_CR7","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1182\/blood-2005-01-0023","volume":"106","author":"KD Puri","year":"2005","unstructured":"Puri, K.D., T.A. Doggett, C.Y. Huang, J. Douangpanya, J.S. Hayflick, M. Turner, J. Penninger, and T.G. Diacovo. 2005. The role of endothelial PI3Kgamma activity in neutrophil trafficking. Blood 106(1): 150\u2013157.","journal-title":"Blood"},{"issue":"1","key":"9636_CR8","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1182\/blood-2004-10-4041","volume":"106","author":"V Munugalavadla","year":"2005","unstructured":"Munugalavadla, V., J. Borneo, D.A. Ingram, and R. Kapur. 2005. p85alpha subunit of class IA PI-3 kinase is crucial for macrophage growth and migration. Blood 106(1): 103\u2013109.","journal-title":"Blood"},{"issue":"3","key":"9636_CR9","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1111\/j.1525-1594.2012.01568.x","volume":"37","author":"JB Huang","year":"2013","unstructured":"Huang, J.B., Y. Ding, D.S. Huang, A.J. Liang, W.K. Zeng, Z.P. Zeng, et al. 2013. Inhibition of the PI3K\/AKT pathway reduces tumor necrosis factor-alpha production in the cellular response to wear particles in vitro. Artificial Organs 37(3): 298\u2013307.","journal-title":"Artificial Organs"},{"issue":"3","key":"9636_CR10","doi-asserted-by":"crossref","first-page":"127","DOI":"10.2302\/kjm.54.127","volume":"54","author":"BF Boyce","year":"2005","unstructured":"Boyce, B.F., P. Li, Z. Yao, Q. Zhang, I.R. Badell, E.M. Schwarz, R.J. O\u2019Keefe, and L. Xing. 2005. TNF-alpha and pathologic bone resorption. The Keio Journal of Medicine 54(3): 127\u2013131.","journal-title":"The Keio Journal of Medicine"},{"issue":"1","key":"9636_CR11","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1042\/BJ20061489","volume":"404","author":"SI Gharbi","year":"2007","unstructured":"Gharbi, S.I., M.J. Zvelebil, S.J. Shuttleworth, T. Hancox, N. Saghir, J.F. Timms, and M.D. Waterfield. 2007. Exploring the specificity of the PI3K family inhibitor LY294002. Biochemical Journal 404(1): 15\u201321.","journal-title":"Biochemical Journal"},{"issue":"9","key":"9636_CR12","doi-asserted-by":"crossref","first-page":"1617","DOI":"10.1248\/bpb.30.1617","volume":"30","author":"K Hazeki","year":"2007","unstructured":"Hazeki, K., K. Nigorikawa, and O. Hazeki. 2007. Role of phosphoinositide 3-kinase in innate immunity. Biological and Pharmaceutical Bulletin 30(9): 1617\u20131623.","journal-title":"Biological and Pharmaceutical Bulletin"},{"issue":"6669","key":"9636_CR13","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1038\/35888","volume":"391","author":"A Fire","year":"1998","unstructured":"Fire, A., S. Xu, M.K. Montgomery, S.A. Kostas, S.E. Driver, and C.C. Mello. 1998. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391(6669): 806\u2013811.","journal-title":"Nature"},{"issue":"1","key":"9636_CR14","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.pharmthera.2007.08.004","volume":"117","author":"M Yang","year":"2008","unstructured":"Yang, M., and J. Mattes. 2008. Discovery, biology and therapeutic potential of RNA interference, microRNA and antagomirs. Pharmacology and Therapeutics 117(1): 94\u2013104.","journal-title":"Pharmacology and Therapeutics"},{"key":"9636_CR15","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/978-3-642-56114-6_11","volume":"261","author":"P Salmon","year":"2002","unstructured":"Salmon, P., and D. Trono. 2002. Lentiviral vectors for the gene therapy of lympho-hematological disorders. Current Topics in Microbiology and Immunology 261: 211\u2013227.","journal-title":"Current Topics in Microbiology and Immunology"},{"issue":"2","key":"9636_CR16","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.orthres.2003.08.013","volume":"22","author":"M Knoch von","year":"2004","unstructured":"von Knoch, M., D.E. Jewison, J.D. Sibonga, C. Sprecher, B.F. Morrey, F. Loer, D.J. Berry, and S.P. Scully. 2004. The effectiveness of polyethylene versus titanium particles in inducing osteolysis in vivo. Journal of Orthopaedic Research 22(2): 237\u2013243.","journal-title":"Journal of Orthopaedic Research"},{"issue":"1","key":"9636_CR17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0736-0266(01)00070-5","volume":"20","author":"EM Greenfield","year":"2002","unstructured":"Greenfield, E.M., Y. Bi, A.A. Ragab, V.M. Goldberg, and R.R. Van De Motter. 2002. The role of osteoclast differentiation in aseptic loosening. Journal of Orthopaedic Research 20(1): 1\u20138.","journal-title":"Journal of Orthopaedic Research"},{"key":"9636_CR18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0378-1119(03)00841-2","volume":"321","author":"MS Nanes","year":"2003","unstructured":"Nanes, M.S. 2003. Tumor necrosis factor-alpha: molecular and cellular mechanisms in skeletal pathology. Gene 321: 1\u201315.","journal-title":"Gene"},{"issue":"4","key":"9636_CR19","doi-asserted-by":"crossref","first-page":"2054","DOI":"10.4049\/jimmunol.180.4.2054","volume":"180","author":"K Tsukamoto","year":"2008","unstructured":"Tsukamoto, K., K. Hazeki, M. Hoshi, K. Nigorikawa, N. Inoue, T. Sasaki, and O. Hazeki. 2008. Critical roles of the p110 beta subtype of phosphoinositide 3-kinase in lipopolysaccharide-induced Akt activation and negative regulation of nitrite production in RAW 264.7 cells. Journal of Immunology 180(4): 2054\u20132061.","journal-title":"Journal of Immunology"},{"issue":"5","key":"9636_CR20","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.2106\/JBJS.F.00615","volume":"89","author":"MV Smith","year":"2007","unstructured":"Smith, M.V., M.J. Lee, A.S. Islam, J.L. Rohrer, V.M. Goldberg, M.A. Beidelschies, and E.M. Greenfield. 2007. Inhibition of the PI3K-Akt signaling pathway reduces tumor necrosis factor-alpha production in response to titanium particles in vitro. The Journal of Bone and Joint Surgery. American Volume 89(5): 1019\u20131027.","journal-title":"The Journal of Bone and Joint Surgery. American Volume"},{"key":"9636_CR21","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.bioeng.2006.01.002","volume":"23","author":"AL Gartel","year":"2006","unstructured":"Gartel, A.L., and E.S. Kandel. 2006. RNA interference in cancer. Biomolecular Engineering 23: 17\u201334.","journal-title":"Biomolecular Engineering"},{"issue":"1","key":"9636_CR22","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1261\/rna5160904","volume":"10","author":"SP Persengiev","year":"2004","unstructured":"Persengiev, S.P., X. Zhu, and M.R. Green. 2004. Nonspecific, concentration-dependent stimulation and repression of mammalian gene expression by small interfering RNAs (siRNAs). RNA 10(1): 12\u201318.","journal-title":"RNA"},{"key":"9636_CR23","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0167-7799(02)00042-2","volume":"21","author":"K Lundstrom","year":"2003","unstructured":"Lundstrom, K. 2003. Latest development in viral vectors for gene therapy. Trends in Biotechnology 21: 117\u2013122.","journal-title":"Trends in Biotechnology"},{"issue":"12","key":"9636_CR24","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1002\/iub.399","volume":"62","author":"C Rovira","year":"2010","unstructured":"Rovira, C., M.C. Guida, and A. Cayota. 2010. MicroRNAs and other small silencing RNAs in cancer. IUBMB Life 62(12): 859\u2013868.","journal-title":"IUBMB Life"},{"issue":"5","key":"9636_CR25","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1016\/j.coph.2010.06.007","volume":"10","author":"LB Couto","year":"2010","unstructured":"Couto, L.B., and K.A. High. 2010. Viral vector-mediated RNA interference. Current Opinion in Pharmacology 10(5): 534\u2013542.","journal-title":"Current Opinion in Pharmacology"},{"issue":"4","key":"9636_CR26","first-page":"274","volume":"11","author":"N Hokaiwado","year":"2008","unstructured":"Hokaiwado, N., F. Takeshita, A. Banas, and T. Ochiya. 2008. RNAi-based drug discovery and its application to therapeutics. IDrugs 11(4): 274\u2013278.","journal-title":"IDrugs"},{"key":"9636_CR27","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1007\/978-1-59745-191-8_8","volume":"442","author":"SQ Harper","year":"2008","unstructured":"Harper, S.Q., and P. Gonzalez-Alegre. 2008. Lentivirus-mediated RNA interference in mammalian neurons. Methods in Molecular Biology 442: 95\u2013112.","journal-title":"Methods in Molecular Biology"},{"key":"9636_CR28","doi-asserted-by":"crossref","first-page":"208","DOI":"10.3109\/08923970903420582","volume":"32","author":"S Froelich","year":"2010","unstructured":"Froelich, S., A. Tai, and P. Wang. 2010. Lentiviral vectors for immune cells targeting. Immunopharmacology and Immunotoxicology 32: 208\u2013218.","journal-title":"Immunopharmacology and Immunotoxicology"},{"issue":"10","key":"9636_CR29","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1002\/jor.20620","volume":"26","author":"R Tsutsumi","year":"2008","unstructured":"Tsutsumi, R., C. Hock, C.D. Bechtold, S.T. Proulx, S.V. Bukata, H. Ito, H.A. Awad, T. Nakamura, R.J. O\u2019Keefe, and E.M. Schwarz. 2008. Differential effects of biologic versus bisphosphonate inhibition of wear debris-induced osteolysis assessed by longitudinal micro-CT. Journal of Orthopaedic Research 26(10): 1340\u20131346.","journal-title":"Journal of Orthopaedic Research"},{"issue":"4","key":"9636_CR30","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1038\/sj.gt.3302202","volume":"11","author":"PH Wooley","year":"2004","unstructured":"Wooley, P.H., and E.M. Schwarz. 2004. Aseptic loosening. Gene Therapy 11(4): 402\u2013407.","journal-title":"Gene Therapy"}],"container-title":["Inflammation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10753-013-9636-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10753-013-9636-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10753-013-9636-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,13]],"date-time":"2022-02-13T17:04:37Z","timestamp":1644771877000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10753-013-9636-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,4,13]]},"references-count":30,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2013,10]]}},"alternative-id":["9636"],"URL":"https:\/\/doi.org\/10.1007\/s10753-013-9636-9","relation":{},"ISSN":["0360-3997","1573-2576"],"issn-type":[{"value":"0360-3997","type":"print"},{"value":"1573-2576","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,4,13]]}}}