{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T20:19:11Z","timestamp":1789935551213,"version":"4.0.1"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2014,6,11]],"date-time":"2014-06-11T00:00:00Z","timestamp":1402444800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Inflammation"],"published-print":{"date-parts":[[2014,12]]},"DOI":"10.1007\/s10753-014-9944-8","type":"journal-article","created":{"date-parts":[[2014,6,10]],"date-time":"2014-06-10T17:12:03Z","timestamp":1402420323000},"page":"2099-2105","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Interleukin-20 Promotes Airway Remodeling in Asthma"],"prefix":"10.1007","volume":"37","author":[{"given":"Wenbin","family":"Gong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuguo","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junqing","family":"Hao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunyan","family":"Xing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Chu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guicheng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiping","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junfei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tian","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanyuan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liang","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2014,6,11]]},"reference":[{"key":"9944_CR1","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/S0300-2896(11)70014-X","volume":"47","author":"D Ramos-Barb\u00f3n","year":"2011","unstructured":"Ramos-Barb\u00f3n, D., and A. Parra-Arrondo. 2011. Inflammation and remodeling of the distal airways: studies in humans and experimental models]. Archivos de Bronconeumolog\u00eda 47: 2.","journal-title":"Archivos de Bronconeumolog\u00eda"},{"key":"9944_CR2","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1016\/j.jaci.2007.06.031","volume":"120","author":"T Mauad","year":"2007","unstructured":"Mauad, T., E.H. Bel, and P.J. Sterk. 2007. Asthma therapy and airway remodeling. Journal of Allergy and Clinical Immunology 120: 997\u20131009.","journal-title":"Journal of Allergy and Clinical Immunology"},{"key":"9944_CR3","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1152\/physiol.00035.2004","volume":"20","author":"RJ Homer","year":"2005","unstructured":"Homer, R.J., and J.A. Elias. 2005. Airway remodeling in asthma: therapeutic implications of mechanisms. Physiology 20: 28\u201335.","journal-title":"Physiology"},{"key":"9944_CR4","doi-asserted-by":"crossref","unstructured":"Shifren A, Witt C, Christie C, Castro M. Mechanisms of remodeling in asthmatic airways. Journal of allergy 2012; 2012.","DOI":"10.1155\/2012\/316049"},{"key":"9944_CR5","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0092-8674(01)00187-8","volume":"104","author":"H Blumberg","year":"2001","unstructured":"Blumberg, H., D. Conklin, W. Xu, A. Grossmann, T. Brender, S. Carollo, et al. 2001. Interleukin 20: discovery, receptor identification, and role in epidermal function. Cell 104: 9\u201319.","journal-title":"Cell"},{"key":"9944_CR6","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1196\/annals.1423.039","volume":"1110","author":"K Stenderup","year":"2007","unstructured":"Stenderup, K., C. Rosada, A. Worsaae, J.T. Clausen, and D.T. Norman. 2007. Interleukin\u201020 as a target in psoriasis treatment. Annals of the New York Academy of Sciences 1110: 368\u2013381.","journal-title":"Annals of the New York Academy of Sciences"},{"key":"9944_CR7","doi-asserted-by":"crossref","first-page":"3545","DOI":"10.4049\/jimmunol.167.7.3545","volume":"167","author":"L Dumoutier","year":"2001","unstructured":"Dumoutier, L., C. Leemans, D. Lejeune, S.V. Kotenko, and J.-C. Renauld. 2001. Cutting edge: STAT activation by IL-19, IL-20 and mda-7 through IL-20 receptor complexes of two types. The Journal of Immunology 167: 3545\u20133549.","journal-title":"The Journal of Immunology"},{"key":"9944_CR8","doi-asserted-by":"crossref","first-page":"R531","DOI":"10.1016\/S0960-9822(01)00312-8","volume":"11","author":"BE Rich","year":"2001","unstructured":"Rich, B.E., and T.S. Kupper. 2001. Cytokines: IL-20\u2014a new effector in skin inflammation. Current Biology 11: R531\u2013R534.","journal-title":"Current Biology"},{"key":"9944_CR9","doi-asserted-by":"crossref","unstructured":"Fonseca-Camarillo G, Furuzawa-Carballeda J, Llorente L, Yamamoto-Furusho JK. IL-10\u2014and IL-20\u2014expressing epithelial and inflammatory cells are increased in patients with ulcerative colitis. Journal of clinical immunology 2012:1-9.","DOI":"10.1007\/s10875-012-9843-4"},{"key":"9944_CR10","doi-asserted-by":"crossref","first-page":"2229","DOI":"10.4049\/jimmunol.178.4.2229","volume":"178","author":"SM Sa","year":"2007","unstructured":"Sa, S.M., P.A. Valdez, J. Wu, K. Jung, F. Zhong, L. Hall, et al. 2007. The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis. The Journal of Immunology 178: 2229\u20132240.","journal-title":"The Journal of Immunology"},{"key":"9944_CR11","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.cyto.2007.10.004","volume":"41","author":"TW Kragstrup","year":"2008","unstructured":"Kragstrup, T.W., K. Otkjaer, C. Holm, A. J\u00f8rgensen, M. Hokland, L. Iversen, et al. 2008. The expression of IL-20 and IL-24 and their shared receptors are increased in rheumatoid arthritis and spondyloarthropathy. Cytokine 41: 16\u201323.","journal-title":"Cytokine"},{"key":"9944_CR12","doi-asserted-by":"crossref","first-page":"2090","DOI":"10.1161\/01.ATV.0000232502.88144.6f","volume":"26","author":"W-Y Chen","year":"2006","unstructured":"Chen, W.-Y., B.-C. Cheng, M.-J. Jiang, M.-Y. Hsieh, and M.-S. Chang. 2006. IL-20 Is expressed in atherosclerosis plaques and promotes atherosclerosis in apolipoprotein E\u2013deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology 26: 2090\u20132095.","journal-title":"Arteriosclerosis, Thrombosis, and Vascular Biology"},{"key":"9944_CR13","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1038\/gene.2008.61","volume":"9","author":"C-C Wei","year":"2008","unstructured":"Wei, C.-C., and M.-S. Chang. 2008. A novel transcript of mouse interleukin-20 receptor acts on glomerular mesangial cells as an aggravating factor in lupus nephritis. Genes and Immunity 9: 668\u2013679.","journal-title":"Genes and Immunity"},{"key":"9944_CR14","doi-asserted-by":"crossref","first-page":"2722","DOI":"10.1002\/art.22039","volume":"54","author":"YH Hsu","year":"2006","unstructured":"Hsu, Y.H., H.H. Li, M.Y. Hsieh, M.F. Liu, K.Y. Huang, L.S. Chin, et al. 2006. Function of interleukin\u201320 as a proinflammatory molecule in rheumatoid and experimental arthritis. Arthritis & Rheumatism 54: 2722\u20132733.","journal-title":"Arthritis & Rheumatism"},{"key":"9944_CR15","doi-asserted-by":"crossref","first-page":"e11","DOI":"10.2500\/ajra.2013.27.3853","volume":"27","author":"SJ Kim","year":"2013","unstructured":"Kim, S.J., J.-H. Shin, S.C. Kim, C.K. Park, and S.W. Kim. 2013. Preventive effects of oral tolerance on allergic inflammation and airway remodeling in a murine model. American Journal of Rhinology & Allergy 27: e11\u2013e16.","journal-title":"American Journal of Rhinology & Allergy"},{"key":"9944_CR16","doi-asserted-by":"crossref","unstructured":"Wu J, Liu F, Zhao J, Wei Y, Lv J, Dong F, et al. Thymic stromal lymphopoietin promotes asthmatic airway remodelling in human lung fibroblast cells through STAT3 signalling pathway. Cell biochemistry and function 2012.","DOI":"10.1002\/cbf.2926"},{"key":"9944_CR17","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1146\/annurev.immunol.22.012703.104622","volume":"22","author":"S Pestka","year":"2004","unstructured":"Pestka, S., C.D. Krause, D. Sarkar, M.R. Walter, Y. Shi, and P.B. Fisher. 2004. Interleukin-10 and related cytokines and receptors. Annual Review of Immunology 22: 929\u2013979.","journal-title":"Annual Review of Immunology"},{"key":"9944_CR18","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1146\/annurev-immunol-031210-101312","volume":"29","author":"W Ouyang","year":"2011","unstructured":"Ouyang, W., S. Rutz, N.K. Crellin, P.A. Valdez, and S.G. Hymowitz. 2011. Regulation and functions of the IL-10 family of cytokines in inflammation and disease. Annual Review of Immunology 29: 71\u2013109.","journal-title":"Annual Review of Immunology"},{"key":"9944_CR19","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1172\/JCI8124","volume":"104","author":"JA Elias","year":"1999","unstructured":"Elias, J.A., Z. Zhu, G. Chupp, and R.J. Homer. 1999. Airway remodeling in asthma. Journal of Clinical Investigation 104: 1001\u20131006.","journal-title":"Journal of Clinical Investigation"},{"key":"9944_CR20","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1186\/1465-9921-6-52","volume":"6","author":"AA Litonjua","year":"2005","unstructured":"Litonjua, A.A., K.G. Tantisira, S. Lake, R. Lazarus, B.G. Richter, S. Gabriel, et al. 2005. Polymorphisms in signal transducer and activator of transcription 3 and lung function in asthma. Respiratory Research 6: 52.","journal-title":"Respiratory Research"},{"key":"9944_CR21","doi-asserted-by":"crossref","first-page":"47517","DOI":"10.1074\/jbc.M205114200","volume":"277","author":"J Parrish-Novak","year":"2002","unstructured":"Parrish-Novak, J., W. Xu, T. Brender, L. Yao, C. Jones, J. West, et al. 2002. Interleukins 19, 20, and 24 signal through two distinct receptor complexes differences in receptor-ligand interactions mediate unique biological functions. Journal of Biological Chemistry 277: 47517\u201347523.","journal-title":"Journal of Biological Chemistry"}],"container-title":["Inflammation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10753-014-9944-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10753-014-9944-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10753-014-9944-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,11]],"date-time":"2019-08-11T11:34:08Z","timestamp":1565523248000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10753-014-9944-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,6,11]]},"references-count":21,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["9944"],"URL":"https:\/\/doi.org\/10.1007\/s10753-014-9944-8","relation":{},"ISSN":["0360-3997","1573-2576"],"issn-type":[{"value":"0360-3997","type":"print"},{"value":"1573-2576","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,6,11]]}}}