{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T12:21:28Z","timestamp":1765887688753},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2015,1,22]],"date-time":"2015-01-22T00:00:00Z","timestamp":1421884800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Inflammation"],"published-print":{"date-parts":[[2015,8]]},"DOI":"10.1007\/s10753-015-0116-2","type":"journal-article","created":{"date-parts":[[2015,1,21]],"date-time":"2015-01-21T03:18:31Z","timestamp":1421810311000},"page":"1415-1423","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Intensive Atorvastatin Therapy Attenuates the Inflammatory Responses in Monocytes of Patients with Unstable Angina Undergoing Percutaneous Coronary Intervention via Peroxisome Proliferator-Activated Receptor \u03b3 Activation"],"prefix":"10.1007","volume":"38","author":[{"given":"Jing","family":"Yang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Changqing","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linxia","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanhui","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aihua","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huiwu","family":"Shi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoxia","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2015,1,22]]},"reference":[{"key":"116_CR1","doi-asserted-by":"crossref","first-page":"579","DOI":"10.2217\/fca.10.77","volume":"6","author":"A Nusca","year":"2010","unstructured":"Nusca, A., R. Melfi, G. Patti, and G.D. Sciascio. 2010. Statin loading before percutaneous coronary intervention: proposed mechanisms and applications. Future Cardiology 6: 579\u201389.","journal-title":"Future Cardiology"},{"key":"116_CR2","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.ijcard.2011.01.033","volume":"158","author":"M Briel","year":"2012","unstructured":"Briel, M., N. Vale, G.G. Schwartz, J.A. de Lemos, F. Colivicchi, F.R. den Hartog, et al. 2012. Updated evidence on early statin therapy for acute coronary syndromes: meta-analysis of 18 randomized trials involving over 14,000 patients. International Journal of Cardiology 158: 93\u2013100.","journal-title":"International Journal of Cardiology"},{"key":"116_CR3","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1161\/01.CIR.0000137828.06205.87","volume":"110","author":"V Pasceri","year":"2004","unstructured":"Pasceri, V., G. Patti, A. Nusca, C. Pristipino, G. Richichi, G. Di Sciascio, et al. 2004. Randomized trial of atorvastatin for reduction of myocardial damage during coronary intervention: results from the ARMYDA (Atorvastatin for Reduction of MYocardial Damage during Angioplasty) study. Circulation 110: 674\u20138.","journal-title":"Circulation"},{"key":"116_CR4","doi-asserted-by":"crossref","first-page":"1560","DOI":"10.1016\/j.jacc.2006.06.061","volume":"48","author":"G Patti","year":"2006","unstructured":"Patti, G., M. Chello, V. Pasceri, D. Colonna, A. Nusca, M. Miglionico, et al. 2006. Protection from procedural myocardial injury by atorvastatin is associated with lower levels of adhesion molecules after percutaneous coronary intervention: results from the ARMYDA-CAMs (Atorvastatin for Reduction of MYocardial Damage during Angioplasty-Cell Adhesion Molecules) substudy. Journal of the American College of Cardiology 48: 1560\u20136.","journal-title":"Journal of the American College of Cardiology"},{"key":"116_CR5","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1016\/j.jacc.2007.02.025","volume":"49","author":"G Patti","year":"2007","unstructured":"Patti, G., V. Pasceri, G. Colonna, M. Miglionico, D. Fischetti, G. Sardella, et al. 2007. Atorvastatin pretreatment improves outcomes in patients with acute coronary syndromes undergoing early percutaneous coronary intervention: results of the ARMYDA-ACS randomized trial. Journal of the American College of Cardiology 49: 1272\u20138.","journal-title":"Journal of the American College of Cardiology"},{"key":"116_CR6","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1097\/CRD.0b013e31826db7ff","volume":"20","author":"DM Norris","year":"2012","unstructured":"Norris, D.M., and J.R. Anderson. 2012. Statin loading before percutaneous coronary intervention to reduce periprocedural myocardial infarction. Cardiology in Review 20: 319\u201324.","journal-title":"Cardiology in Review"},{"key":"116_CR7","doi-asserted-by":"crossref","first-page":"2157","DOI":"10.1016\/j.jacc.2009.07.005","volume":"54","author":"C Briguori","year":"2009","unstructured":"Briguori, C., G. Visconti, A. Focaccio, B. Golia, A. Chieffo, A. Castelli, et al. 2009. Novel approaches for preventing or limiting events (Naples) II trial: impact of a single high loading dose of atorvastatin on periprocedural myocardial infarction. Journal of the American College of Cardiology 54: 2157\u201363.","journal-title":"Journal of the American College of Cardiology"},{"key":"116_CR8","doi-asserted-by":"crossref","first-page":"1679","DOI":"10.1016\/j.ehj.2004.06.011","volume":"25","author":"K Toutouzas","year":"2004","unstructured":"Toutouzas, K., A. Colombo, and C. Stefanadis. 2004. Inflammation and restenosis after percutaneous coronary interventions. European Heart Journal 25: 1679\u201387.","journal-title":"European Heart Journal"},{"key":"116_CR9","doi-asserted-by":"crossref","first-page":"2370","DOI":"10.1161\/01.CIR.98.22.2370","volume":"98","author":"G Liuzzo","year":"1998","unstructured":"Liuzzo, G., A. Buffon, L.M. Biasucci, J.R. Gallimore, G. Caligiuri, A. Vitelli, et al. 1998. Enhanced inflammatory response to coronary angioplasty in patients with severe unstable angina. Circulation 98: 2370\u20136.","journal-title":"Circulation"},{"key":"116_CR10","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.jacc.2006.07.071","volume":"49","author":"G Liuzzo","year":"2007","unstructured":"Liuzzo, G., M. Santamaria, L.M. Biasucci, M. Narducci, V. Colafrancesco, A. Porto, et al. 2007. Persistent activation of nuclear factor kappa-B signaling pathway in patients with unstable angina and elevated levels of C-reactive protein evidence for a direct proinflammatory effect of azide and lipopolysaccharide-free C-reactive protein on human monocytes via nuclear factor kappa-B activation. Journal of the American College of Cardiology 49: 185\u201394.","journal-title":"Journal of the American College of Cardiology"},{"key":"116_CR11","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1111\/j.1365-2796.2005.01509.x","volume":"258","author":"GD Norata","year":"2005","unstructured":"Norata, G.D., K. Garlaschelli, M. Ongari, S. Raselli, L. Grigore, F. Benvenuto, et al. 2005. Effect of the Toll-like receptor 4 (TLR-4) variants on intima-media thickness and monocyte-derived macrophage response to LPS. Journal of Internal Medicine 258: 21\u20137.","journal-title":"Journal of Internal Medicine"},{"key":"116_CR12","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1196\/annals.1354.037","volume":"1067","author":"G Candore","year":"2006","unstructured":"Candore, G., A. Aquino, C.R. Balistreri, M. Bulati, D. Di Carlo, M.P. Grimaldi, et al. 2006. Inflammation, longevity, and cardiovascular diseases: role of polymorphisms of TLR4. Annals of the New York Academy of Sciences 1067: 282\u20137.","journal-title":"Annals of the New York Academy of Sciences"},{"key":"116_CR13","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1038\/nri1391","volume":"4","author":"S Akira","year":"2004","unstructured":"Akira, S., and K. Takeda. 2004. Toll-like receptor signalling. Nature Reviews Immunology 4: 499\u2013511.","journal-title":"Nature Reviews Immunology"},{"key":"116_CR14","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1189\/jlb.0305127","volume":"79","author":"N Sakai","year":"2006","unstructured":"Sakai, N., T. Wada, K. Furuichi, K. Shimizu, S. Kokubo, A. Hara, et al. 2006. MCP-1\/CCR2-dependent loop for fibrogenesis in human peripheral CD14-positive monocytes. Journal of Leukocyte Biology 79: 555\u201363.","journal-title":"Journal of Leukocyte Biology"},{"key":"116_CR15","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1161\/01.RES.0000149518.86865.3e","volume":"95","author":"A Schober","year":"2004","unstructured":"Schober, A., A. Zernecke, E.A. Liehn, P. von Hundelshausen, S. Knarren, W.A. Kuziel, et al. 2004. Crucial role of the CCL2\/CCR2 axis in neointimal hyperplasia after arterial injury in hyperlipidemic mice involves early monocyte recruitment and CCL2 presentation on platelets. Circulation Research 95: 1125\u201333.","journal-title":"Circulation Research"},{"key":"116_CR16","doi-asserted-by":"crossref","first-page":"193","DOI":"10.2174\/157489006777442441","volume":"1","author":"SK Das","year":"2006","unstructured":"Das, S.K., and R. Chakrabarti. 2006. Role of PPAR in cardiovascular diseases. Recent Patents on Cardiovascular Drug Discovery 1: 193\u2013209.","journal-title":"Recent Patents on Cardiovascular Drug Discovery"},{"key":"116_CR17","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/S1471-4892(03)00014-6","volume":"3","author":"GA Francis","year":"2003","unstructured":"Francis, G.A., J.S. Annicotte, and J. Auwerx. 2003. PPAR agonists in the treatment of atherosclerosis. Current Opinion in Pharmacology 3: 186\u201391.","journal-title":"Current Opinion in Pharmacology"},{"key":"116_CR18","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1007\/BF02684000","volume":"51","author":"O Grip","year":"2002","unstructured":"Grip, O., S. Janciauskiene, and S. Lindgren. 2002. Atorvastatin activates PPAR-gamma and attenuates the inflammatory response in human monocytes. Inflammation Research: Official Journal of the European Histamine Research Society [et al] 51: 58\u201362.","journal-title":"Inflammation Research: Official Journal of the European Histamine Research Society [et al]"},{"key":"116_CR19","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1161\/01.RES.0000268411.49545.9c","volume":"100","author":"M Yano","year":"2007","unstructured":"Yano, M., T. Matsumura, T. Senokuchi, N. Ishii, Y. Murata, K. Taketa, et al. 2007. Statins activate peroxisome proliferator-activated receptor gamma through extracellular signal-regulated kinase 1\/2 and p38 mitogen-activated protein kinase-dependent cyclooxygenase-2 expression in macrophages. Circulation Research 100: 1442\u201351.","journal-title":"Circulation Research"},{"key":"116_CR20","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1515\/CCLM.2002.132","volume":"40","author":"V Sanchez-Margalet","year":"2002","unstructured":"Sanchez-Margalet, V., J.M. Cubero, C. Martin-Romero, J. Cubero, J.M. Cruz-Fernandez, and R. Goberna. 2002. Inflammatory response to coronary stent implantation in patients with unstable angina. Clinical Chemistry and Laboratory Medicine: CCLM \/ FESCC 40: 769\u201374.","journal-title":"Clinical Chemistry and Laboratory Medicine: CCLM \/ FESCC"},{"key":"116_CR21","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1001\/archinternmed.2011.2275","volume":"172","author":"V Novack","year":"2012","unstructured":"Novack, V., M. Pencina, D.J. Cohen, N.S. Kleiman, C.H. Yen, J.F. Saucedo, et al. 2012. Troponin criteria for myocardial infarction after percutaneous coronary intervention. Archives of Internal Medicine 172: 502\u20138.","journal-title":"Archives of Internal Medicine"},{"key":"116_CR22","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1007\/s00011-011-0356-z","volume":"60","author":"TI Arefieva","year":"2011","unstructured":"Arefieva, T.I., T.L. Krasnikova, A.V. Potekhina, N.U. Ruleva, P.I. Nikitin, T.I. Ksenevich, et al. 2011. Synthetic peptide fragment (65-76) of monocyte chemotactic protein-1 (MCP-1) inhibits MCP-1 binding to heparin and possesses anti-inflammatory activity in stable angina patients after coronary stenting. Inflammation Research: Official Journal of the European Histamine Research Society [et al] 60: 955\u201364.","journal-title":"Inflammation Research: Official Journal of the European Histamine Research Society [et al]"},{"key":"116_CR23","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1161\/01.RES.0000163017.13772.3a","volume":"96","author":"O Dewald","year":"2005","unstructured":"Dewald, O., P. Zymek, K. Winkelmann, A. Koerting, G. Ren, T. Abou-Khamis, et al. 2005. CCL2\/Monocyte Chemoattractant Protein-1 regulates inflammatory responses critical to healing myocardial infarcts. Circulation Research 96: 881\u20139.","journal-title":"Circulation Research"},{"key":"116_CR24","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1161\/CIRCULATIONAHA.106.646091","volume":"115","author":"NG Frangogiannis","year":"2007","unstructured":"Frangogiannis, N.G., O. Dewald, Y. Xia, G. Ren, S. Haudek, T. Leucker, et al. 2007. Critical role of monocyte chemoattractant protein-1\/CC chemokine ligand 2 in the pathogenesis of ischemic cardiomyopathy. Circulation 115: 584\u201392.","journal-title":"Circulation"},{"key":"116_CR25","doi-asserted-by":"crossref","first-page":"e74","DOI":"10.1182\/blood-2010-02-258558","volume":"116","author":"L Ziegler-Heitbrock","year":"2010","unstructured":"Ziegler-Heitbrock, L., P. Ancuta, S. Crowe, M. Dalod, V. Grau, D.N. Hart, et al. 2010. Nomenclature of monocytes and dendritic cells in blood. Blood 116: e74\u201380.","journal-title":"Blood"}],"container-title":["Inflammation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10753-015-0116-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10753-015-0116-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10753-015-0116-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,30]],"date-time":"2019-05-30T23:42:41Z","timestamp":1559259761000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10753-015-0116-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1,22]]},"references-count":25,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,8]]}},"alternative-id":["116"],"URL":"https:\/\/doi.org\/10.1007\/s10753-015-0116-2","relation":{},"ISSN":["0360-3997","1573-2576"],"issn-type":[{"value":"0360-3997","type":"print"},{"value":"1573-2576","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,1,22]]}}}